Marco Mottinelli

发表

Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue

D. Mann, M. Kassiou, A. Jacobs, 2020, Theranostics.

Efficient preparation of an N-aryl β-amino acid via asymmetric hydrogenation and direct asymmetric reductive amination en route to Ezetimibe

J. G. Vries, L. Lefort, K. Matsumura, 2010 .

Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain

T. Cirino, Amy R Alleyne, S. Eans, 2022, Molecules.

Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.

C. McCurdy, Clinton E. Canal, T. Hiranita, 2021, Journal of medicinal chemistry.

Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats

Tobias Braun, J. Wilkerson, J. Fortner, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5.

G. Giannaccini, A. Lucacchini, T. Tuccinardi, 2011, Bioorganic & medicinal chemistry letters.

Accessing simply-substituted 4-hydroxytetrahydroisoquinolines via Pomeranz–Fritsch–Bobbitt reaction with non-activated and moderately-activated systems

B. Potter, M. Leese, Marco Mottinelli, 2017, Beilstein journal of organic chemistry.

Highly Specific Sigma Receptor Ligands Exhibit Anti-Viral Properties in SARS-CoV-2 Infected Cells

F. Vizeacoumar, Kalpana K Bhanumathy, D. Falzarano, 2021, Pathogens.

Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives

W. Bowen, C. McCurdy, C. Mesangeau, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain

T. Cirino, S. Eans, J. M. Medina, 2019, Front. Pharmacol..

Identification and characterization of MAM03055A: a novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity.

W. Bowen, C. McCurdy, Hilary E. Nicholson, 2021, European journal of pharmacology.

In Vitro and In Vivo Pharmacological Comparison of Mu‐Opioid Receptor Activity of the Kratom (Mitragyna speciosa) Alkaloid Mitragynine and its Metabolite 7‐Hydroxymitragynine

C. McCurdy, T. Hiranita, L. McMahon, 2021, Alzheimer's & Dementia.

Metabolism of Speciociliatine, an Overlooked Kratom Alkaloid for its Potential Pharmacological Effects

Abhisheak Sharma, L. McMahon, Marco Mottinelli, 2022, The AAPS Journal.

The Lack of Contribution of 7-Hydroxymitragynine to the Antinociceptive Effects of Mitragynine in Mice: A Pharmacokinetic and Pharmacodynamic Study

C. McCurdy, T. Hiranita, Abhisheak Sharma, 2021, Drug Metabolism and Disposition.

Directed Biosynthesis of Mitragynine Stereoisomers

S. O’Connor, Thu-Thuy T. Dang, Yindi Jiang, 2022, bioRxiv.

Bioanalytical method development and validation of MES207, a neuropeptide FF receptor antagonist, and its application in preclinical pharmacokinetics.

B. Avery, C. McCurdy, C. Mesangeau, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

N‐Phenyl‐1,2,3,4‐tetrahydroisoquinoline: An Alternative Scaffold for the Design of 17β‐Hydroxysteroid Dehydrogenase 1 Inhibitors

B. Potter, T. Rižner, M. Leese, 2020, ChemMedChem.

Cannabidiol and mitragynine exhibit differential interactive effects in the attenuation of paclitaxel-induced mechanical allodynia, acute antinociception, and schedule-controlled responding in mice

J. Wilkerson, L. McMahon, Marco Mottinelli, 2023, Pharmacological Reports.