P. Raposinho

发表

99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation.

A. Abrantes, M. Botelho, I. Santos, 2012, European journal of medicinal chemistry.

99 mTc ( I ) / Re ( I ) tricarbonyl complexes for in vivo targeting of melanotic melanoma : Synthesis and biological evaluation

A. Abrantes, M. Botelho, I. Santos, 2012 .

Radiometallated peptides for molecular imaging and targeted therapy.

J. Correia, P. Raposinho, A. Paulo, 2011, Dalton transactions.

The Melanocortin Agonist Melanotan‐II Reduces the Orexigenic and Adipogenic Effects of Neuropeptide Y (NPY) but Does not Affect the NPY‐Driven Suppressive Effects on the Gonadotropic and Somatotropic Axes in the Male Rat

M. Aubert, R. B. White, P. Raposinho, 2003, Journal of neuroendocrinology.

Stimulation of the Gonadotropic Axis by the Neuropeptide Y Receptor Y1 Antagonist/ Y4 Agonist 1229U91 in the Male Rat

A. Hayward, M. Aubert, J. Junien, 2000, Neuroendocrinology.

Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism

T. Pedrazzini, M. Aubert, D. Pierroz, 2001, Molecular and Cellular Endocrinology.

Obesity and the reproductive axis.

M. Aubert, F. Pralong, R. Gaillard, 2002, Annales d'endocrinologie.

Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression.

R. Palmiter, T. Pedrazzini, M. Aubert, 2004, Endocrinology.

Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes.

M. Aubert, F. Pralong, P. Raposinho, 2000, Endocrinology.

Evidence That the Inhibition of Luteinizing Hormone Secretion Exerted by Central Administration of Neuropeptide Y (NPY) in the Rat Is Predominantly Mediated by the NPY-Y5 Receptor Subtype1.

R. Quirion, A. Hayward, M. Aubert, 1999, Endocrinology.

Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.

António E. N. Ferreira, B. Oliveira, J. Correia, 2010, Bioconjugate chemistry.

The [(Cp)M(CO)3] (M=Re, 99mTc) Building Block for Imaging Agents and Bioinorganic Probes: Perspectives and Limitations

B. Spingler, R. Alberto, I. Santos, 2012, Chemistry & biodiversity.

Anticancer Activity and Mode of Action of Copper(II)‐Bis(thiosemicarbazonato) Complexes with Pendant Nitrogen Heterocycles

J. Guerreiro, A. Abrunhosa, F. Mendes, 2021 .

Influence of the bifunctional chelator on the pharmacokinetic properties of 99mTc(CO)3-labeled cyclic α-melanocyte stimulating hormone analog.

B. Oliveira, J. Correia, M. C. Oliveira, 2013, Journal of medicinal chemistry.

[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX.

C. Supuran, A. Innocenti, B. Spingler, 2012, Angewandte Chemie.

NMR structural analysis of MC1R-targeted rhenium(I) metallopeptides and biological evaluation of 99mTc(I) congeners

J. Correia, D. Pantoja-Uceda, M. C. Oliveira, 2012 .

A 99mTc(CO)3-labeled pyrazolyl–α-melanocyte-stimulating hormone analog conjugate for melanoma targeting

J. Correia, M. Botelho, P. Raposinho, 2008 .

Pt(IV)/Re(I) Chitosan Conjugates as a Flexible Platform for the Transport of Therapeutic and/or Diagnostic Anticancer Agents

E. Gabano, M. Ravera, E. Perin, 2017 .

Evaluation of novel 99mTc(I)-labeled homobivalent α-melanocyte-stimulating hormone analogs for melanocortin-1 receptor targeting

J. Correia, M. Morais, P. Raposinho, 2012, JBIC Journal of Biological Inorganic Chemistry.

Searching for a Paradigm Shift in Auger-Electron Cancer Therapy with Tumor-Specific Radiopeptides Targeting the Mitochondria and/or the Cell Nucleus

Hugo M. Botelho, J. Guerreiro, A. Belchior, 2022, International journal of molecular sciences.

Radiolabeled Gold Nanoseeds Decorated with Substance P Peptides: Synthesis, Characterization and In Vitro Evaluation in Glioblastoma Cellular Models

Josué Carvalho, C. Cruz, A. Belchior, 2022, International journal of molecular sciences.

Melanoma targeting with α-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: effect of cyclization on tumor-seeking properties

J. Correia, S. Falcão, C. Xavier, 2008, JBIC Journal of Biological Inorganic Chemistry.

Thiosemicarbazonate complexes with affinity for amyloid-β fibers: synthesis, characterization and biological studies.

E. Vázquez-López, Arantxa Pino-Cuevas, R. Carballo, 2019, Future medicinal chemistry.

Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes.

A. Abrunhosa, I. Correia, F. Mendes, 2017, Journal of inorganic biochemistry.

Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies

Hugo M. Botelho, A. Belchior, I. Correia, 2018, JBIC Journal of Biological Inorganic Chemistry.

Tricarbonyl M(I) (M = Re, (99m)Tc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting.

G. Viola, J. Rino, J. Pessoa, 2010, Organic & biomolecular chemistry.

A pyrazolylamine‐phosphonate monoester chelator for the fac‐[M(CO)3]+ core (M = Re, 99mTc): synthesis, coordination properties and biological assessment

B. Oliveira, J. Correia, P. Raposinho, 2007 .

Synthesis, characterization and biological evaluation of tricarbonyl M(I) (M = Re, 99mTc) complexes functionalized with melanin-binding pharmacophores

I. Santos, L. Gano, C. Moura, 2010 .

NMR Insights into the Structure-Function Relationships in the Binding of Melanocortin Analogues to the MC1R Receptor

J. Correia, D. Pantoja-Uceda, M. Jiménez, 2017, Molecules.

Preparation and biological evaluation of cyclopentadienyl-based 99mTc-complexes [(Cp-R)99mTc(CO)3] mimicking benzamides for malignant melanoma targeting.

Célia Fernandes, Isabel Santos, Paul Schmutz, 2010, Nuclear medicine and biology.

Towards (99m)Tc-based imaging agents with effective doxorubicin mimetics: a molecular and cellular study.

G. Gasser, T. Fox, R. Alberto, 2016, Dalton transactions.

Leptin, Growth and Reproduction

F. Pralong, M. Aubert, D. Pierroz, 2002 .

Leptin and human reproduction

N. Gruaz-Gumowski, F. Pralong, M. Aubert, 2000 .

Evidence that the inhibition of luteinizing hormone secretion exerted by central administration of neuropeptide Y (NPY) in the rat is predominantly mediated by the NPY-Y5 receptor subtype.

R. Quirion, A. Hayward, M. Aubert, 1999, Endocrinology.

Nuclear Targeting with an Auger Electron Emitter Potentiates the Action of a Widely Used Antineoplastic Drug.

R. Freudenberg, G. Gasser, T. Fox, 2015, Bioconjugate chemistry.

Radiobiological and dosimetric assessment of DNA-intercalated 99mTc-complexes bearing acridine orange derivatives

P. Vaz, A. Belchior, P. Raposinho, 2020, EJNMMI Research.

Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNA

P. Vaz, J. Lavrado, A. Belchior, 2017, Scientific Reports.

Melanocortin-1 receptor-targeting with radiolabeled cyclic α-melanocyte-stimulating hormone analogs for melanoma imaging.

J. Correia, P. Raposinho, I. Santos, 2010, Biopolymers.

Re and (99m)Tc organometallic complexes containing pendant l-arginine derivatives as potential probes of inducible nitric oxide synthase.

B. Oliveira, J. Correia, C. Cordeiro, 2009, Dalton transactions.

Combining imaging and anticancer properties with new heterobimetallic Pt(ii)/M(i) (M = Re, 99mTc) complexes.

G. Gasser, R. Rubbiani, H. Chao, 2017, Dalton transactions.

Comparative Study of Chemical Approaches to the Solid-Phase Synthesis of a Tumor-Seeking α-MSH Analogue

J. Correia, C. Xavier, Paula Gomes, 2008, International Journal of Peptide Research and Therapeutics.

Technetium-99m complexes of l-arginine derivatives for targeting amino acid transporters.

B. Oliveira, J. Correia, I. Santos, 2017, Dalton transactions.

(99m)Tc-tricarbonyl complexes functionalized with anthracenyl fragments: synthesis, characterization, and evaluation of their radiotoxic effects in murine melanoma cells.

S. Casimiro, L. Costa, I. Santos, 2009, Cancer biotherapy & radiopharmaceuticals.

Targeting nitric oxide synthase with 99mTc/Re-tricarbonyl complexes containing pendant guanidino or isothiourea moieties

Isabel M. Santos, António E. N. Ferreira, B. Oliveira, 2011 .

Synthesis and Biological Evaluation of 99mTc(I) Tricarbonyl Complexes Dual-Targeted at Tumoral Mitochondria

P. Vaz, A. Belchior, P. Raposinho, 2021, Molecules.

Nuclear Targeting with an Auger Electron Emitter Potentiates the Action of a Widely Used Antineoplastic Drug.

R. Freudenberg, G. Gasser, T. Fox, 2015, Bioconjugate chemistry.