A. Lindner

发表

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer

J. Prehn, E. Kay, J. Fay, 2015, Radiation oncology.

Systems Analysis of Cancer Cell Heterogeneity in Caspase-dependent Apoptosis Subsequent to Mitochondrial Outer Membrane Permeabilization*

M. Rehm, J. Prehn, H. Huber, 2012, The Journal of Biological Chemistry.

Systems analysis of protein signatures predicting cetuximab responses in KRAS, NRAS, BRAF and PIK3CA wild‐type patient‐derived xenograft models of metastatic colorectal cancer

L. Trusolino, A. Bertotti, B. Hennessy, 2020, International journal of cancer.

ArticleImplementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-

P. Lambin, S. Keek, H. Woodruff, 2020 .

Bcl-xL Is a Key Mediator of Apoptosis Following KRASG12C Inhibition in KRASG12C-mutant Colorectal Cancer

A. Bardelli, S. McDade, M. LaBonte, 2022, bioRxiv.

Apoptotic and Necroptotic Mediators are Differentially Expressed in Mucinous and Non-Mucinous Colorectal Cancer

D. Longley, J. Prehn, Sanghee Cho, 2022, Frontiers in Oncology.

Stratification of Chemotherapy-Treated Stage III Colorectal Cancer Patients Using Multiplexed Imaging and Single Cell Analysis of T Cell Populations

D. Longley, P. Laurent-Puig, A. Corwin, 2021, bioRxiv.

Erratum to: Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer

J. Prehn, C. Concannon, E. Kay, 2016, Journal of Translational Medicine.

FLINO: a new method for immunofluorescence bioimage normalization

Fiona Ginty, Anup Sood, Xanthi Stachtea, 2021, Bioinform..

Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations

D. Longley, P. Laurent-Puig, A. Corwin, 2021, Modern Pathology.

Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer

D. Lambrechts, J. Tabernero, R. Dienstmann, 2021, Clinical Cancer Research.

BCL-2 system analysis identifies high-risk colorectal cancer patients

Manuel Salto-Tellez, Pierre Laurent-Puig, Jochen H M Prehn, 2016, Gut.

A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer

Mark Lawler, Manuel Salto-Tellez, Pierre Laurent-Puig, 2016, Clinical Cancer Research.

BCL2 protein signalling determines acute responses to neoadjuvant chemoradiotherapy in rectal cancer

B. Hennessy, J. Prehn, E. Kay, 2015, Journal of Molecular Medicine.

An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution

D. Longley, P. Laurent-Puig, P. Dunne, 2021, Cell Death & Differentiation.

Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers

A. Hill, J. Prehn, W. Gallagher, 2018, Journal of Molecular Medicine.

Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy.

Jochen H M Prehn, Deborah A McNamara, Elaine W Kay, 2013, Cancer research.

Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells

H. Düssmann, J. Prehn, Federico Lucantoni, 2018, Cell Death & Disease.

Systems biology analysis identifies molecular determinants of chemotherapy-induced diarrhoea

J. Burke, K. Sheahan, B. Hennessy, 2019, Journal of Molecular Medicine.

Caspase modelling to predict personalised risk in stage III colorectal cancer (CRC) patients.

M. Salto‐Tellez, D. Longley, P. Laurent-Puig, 2016 .

A systems model of BCL-2 dependent apoptosis to predict stage II CRC patients benefiting from adjuvant chemotherapy and as a prognostic tool for stage III CRC patients with increased risk of recurrence.

M. Salto‐Tellez, P. Johnston, P. Laurent-Puig, 2016 .

The indirect activation model of mitochondrial outer membrane permeabilisation (MOMP) initiation requires a trade-off between robustness in the absence of and sensitivity in the presence of stress.

Jochen H M Prehn, J. Prehn, H. Huber, 2013, Molecular bioSystems.

BCL(X)L and BCL2 increase the metabolic fitness of breast cancer cells: a single-cell imaging study

D. Lambrechts, H. Düssmann, J. Prehn, 2020, Cell Death & Differentiation.

Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models

P. Lambin, S. Keek, H. Woodruff, 2020, Cancers.

Multiplexed Immunofluorescence Imaging Reveals an Immune-Rich Tumor Microenvironment in Mucinous Rectal Cancer Characterized by Increased Lymphocyte Infiltration and Enhanced Programmed Cell Death Protein 1 Expression

D. Longley, J. Prehn, E. McDonough, 2022, Diseases of the colon and rectum.

Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer

J. Prehn, C. Concannon, E. Kay, 2016, Journal of Translational Medicine.

Systems biology analysis identifies molecular determinants of chemotherapy-induced diarrhoea

K. Sheahan, B. Hennessy, J. Prehn, 2019, Journal of Molecular Medicine.

Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer

G. Cagney, A. Letai, M. Hemann, 2021, Science Advances.

Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.

A. Vazquez, D. Green, R. McLendon, 2013, Cancer research.

The indirect activation model of mitochondrial outer membrane permeabilisation (MOMP) initiation requires a trade-off between robustness in the absence of and sensitivity in the presence of stress.

J. Prehn, H. Huber, A. Lindner, 2013, Molecular bioSystems.