D. Weng

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Small Molecule Therapeutics Birinapant ( TL 32711 ) , a Bivalent SMAC Mimetic , Targets TRAF 2-Associated cIAPs , Abrogates TNF-Induced NFk B Activation , and Is Active in Patient-Derived Xenograft Models

Yigong Shi, G. Kapoor, Y. Mitsuuchi, 2014 .

Discrete Signaling Pathways Dendritic Cell-Like Characteristics Through Cells Results in Acquisition of Individual Calcium Mobilization in Human Myeloid

B. Czerniecki, R. Gress, C. Carter, 1999 .

Differential gene expression in fetal mouse germ cells.

J. Gearhart, J. McCarrey, D. Weng, 1993, Biology of reproduction.

A phase I clinical trial of a ribozyme-based angiogenesis inhibitor targeting vascular endothelial growth factor receptor-1 for patients with refractory solid tumors

E. Borden, J. Cowens, R. Ganapathi, 2005, Molecular Cancer Therapeutics.

T-Cell Adoptive Immunotherapy

G. Plautz, P. Cohen, S. Shu, 2004 .

A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma

A. Adjei, M. Levin, R. Amaravadi, 2015, Molecular Cancer Therapeutics.

Status, or Sensitivity to Biologic Agents Characteristics Independent of Prior Differentiation State, Transformation Calcium Ionophore-Treated Myeloid Cells Acquire Many Dendritic Cell

B. Czerniecki, R. Gress, P. Cohen, 2013 .

Calcium ionophore-treated myeloid cells acquire many dendritic cell characteristics independent of prior differentiation state, transformation status, or sensitivity to biologic agents.

B. Czerniecki, M. Tsokos, R. Gress, 1999, Blood.

Progression Naturally Sensitized During Tumor Cells with Broad Anti-Tumor Efficacy Are T + CD 8 lowHelper-Independent , L-Selectin

G. Plautz, P. Cohen, J. Kjaergaard, 2000 .

Estimates of mRNA abundance in the mouse blastocyst based on cDNA library analysis

R. Morgan, J. Gearhart, D. Weng, 1989, Molecular reproduction and development.

Calcium ionophore-treated peripheral blood monocytes and dendritic cells rapidly display characteristics of activated dendritic cells.

B. Czerniecki, S. Rosenberg, L. Rivoltini, 1997, Journal of immunology.

CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection.

G. Plautz, P. Cohen, J. Kim, 2000, Critical reviews in immunology.

Inhibition of the conversion of 3T3 fibroblast clones to adipocytes by dehydroepiandrosterone and related anticarcinogenic steroids.

G. Gordon, L. Shantz, P. Talalay, 1986, Cancer research.

Detection of circulating tumor cells and micrometastases in Stage II, III, and IV breast cancer patients utilizing cytology and immunocytochemistry

K. Cowan, P. Fetsch, A. Abati, 2000, Diagnostic cytopathology.

Loss of expression of the uvomorulin gene in compaction-defective embryonal carcinoma cells

J. Littlefield, D. Weng, 1991, Somatic cell and molecular genetics.

Inhibition of the conversion of 3T3 fibroblast clones to adipocytes by dehydroepiandrosterone and related anticarcinogenic steroids.

G. Gordon, L. Shantz, P. Talalay, 1986, Cancer research.

Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2–positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib

D. Jackson, S. Coats, B. Jallal, 2009, Molecular Cancer Therapeutics.

Birinapant (TL32711), a Bivalent SMAC Mimetic, Targets TRAF2-Associated cIAPs, Abrogates TNF-Induced NF-κB Activation, and Is Active in Patient-Derived Xenograft Models

Yigong Shi, G. Kapoor, Y. Mitsuuchi, 2014, Molecular Cancer Therapeutics.

Calcium mobilization in human myeloid cells results in acquisition of individual dendritic cell-like characteristics through discrete signaling pathways.

B. Czerniecki, R. Gress, P. Cohen, 1999, Journal of immunology.

A phase I study of birinapant (TL32711) combined with multiple chemotherapies evaluating tolerability and clinical activity for solid tumor patients.

N. Senzer, P. LoRusso, K. Papadopoulos, 2013 .

Abstract A25: Phase 1 PK/PD analysis of the Smac-mimetic TL32711 demonstrates potent and sustained cIAP1 suppression in patient PBMCs and tumor biopsies.

A. Tolcher, P. LoRusso, K. Papadopoulos, 2011 .

An open‐label, phase 2 trial of RPI.4610 (angiozyme) in the treatment of metastatic breast cancer

G. Hortobagyi, H. Rugo, W. Urba, 2012, Cancer.

Identification of elf1, a beta-spectrin, in early mouse liver development.

Ariel J. Levine, J. Gearhart, L. Mishra, 1998, The International journal of developmental biology.

Phase II clinical activity and tolerability of the SMAC-mimetic birinapant (TL32711) plus irinotecan in irinotecan-relapsed/refractory metastatic colorectal cancer.

N. Senzer, P. LoRusso, K. Papadopoulos, 2013 .

Pharmacodynamic biomarkers from phase II study of the SMAC (Second Mitochondrial-Derived Activator of Caspases)-mimetic birinapant (TL32711; NSC 756502) in relapsed platinum-resistant epithelial ovarian cancer (EOC), primary peritoneal cancer (PPC), or fallopian tube cancer (FTC) (NCT01681368).

E. Kohn, Jung-Min Lee, C. Annunziata, 2014 .

Successful medical management of isolated renal zygomycosis: case report and review.

W. Wilson, T. Walsh, R. Little, 1998, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.