J. McCarthy

发表

RIP2 Is a Novel NF-κB-activating and Cell Death-inducing Kinase*

V. Dixit, J. Ni, J. McCarthy, 1998, The Journal of Biological Chemistry.

Apoptosis Induced by Drosophila Reaper and Grim in a Human System

V. Dixit, J. McCarthy, 1998, The Journal of Biological Chemistry.

Cell shrinkage and apoptosis: a role for potassium and sodium ion efflux

T. Cotter, J. McCarthy, 1997, Cell Death and Differentiation.

Apoptosis and development.

J. McCarthy, 2003, Essays in biochemistry.

Regulated intramembrane proteolysis: emergent role in cell signalling pathways.

J. McCarthy, Aonghus J McCarthy, Caroline Coleman-Vaughan, 2017, Biochemical Society transactions.

Association between Presenilin‐1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor

James C. Powell, J. McCarthy, C. Twomey, 2009, Journal of neurochemistry.

Involvement of presenilins in cell-survival signalling pathways.

J. McCarthy, Justin V. McCarthy, 2005, Biochemical Society transactions.

Beyond γ-secretase activity: The multifunctional nature of presenilins in cell signalling pathways.

J. McCarthy, Stephen P Duggan, Stephen Duggan, 2016, Cellular signalling.

Loss of Presenilin 2 Function Is Associated with Defective LPS-Mediated Innate Immune Responsiveness

V. Agrawal, N. Sawhney, J. McCarthy, 2016, Molecular Neurobiology.

Pathways of apoptosis and importance in developement

J. McCarthy, C. Twomey, Justin V. McCarthy, 2005, Journal of cellular and molecular medicine.

Glycogen Synthase Kinase-3β Regulates Presenilin 1 C-terminal Fragment Levels*

S. Hsu, F. Kirschenbaum, J. McCarthy, 2001, The Journal of Biological Chemistry.

Presenilins are novel substrates for TRAF6-mediated ubiquitination.

J. McCarthy, Run Yan, Sean Farrelly, 2013, Cellular signalling.

Metalloprotease-Dependent S2 (cid:48) -Activation Promotes Cell–Cell Fusion and Syncytiation of SARS-CoV-2

Andrew J. Lindsay, J. McCarthy, Caroline Coleman-Vaughan, 2022 .

Metalloprotease-Dependent S2′-Activation Promotes Cell–Cell Fusion and Syncytiation of SARS-CoV-2

Andrew J. Lindsay, J. McCarthy, Caroline Coleman-Vaughan, 2022, Viruses.

Cell Death in the Myeloid Lineage

T. Cotter, J. McCarthy, R. S. Fernandes, 1994, Immunological reviews.

TRAF6 promotes ubiquitination and regulated intramembrane proteolysis of IL-1R1.

J. McCarthy, C. Twomey, Si Qian, 2009, Biochemical and biophysical research communications.

RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.

V. Dixit, J. Ni, J. McCarthy, 1998, The Journal of biological chemistry.

Substitution of a Glycogen Synthase Kinase-3β Phosphorylation Site in Presenilin 1 Separates Presenilin Function from β-Catenin Signaling*

S. Hsu, F. Kirschenbaum, J. McCarthy, 2001, The Journal of Biological Chemistry.

The γ-Secretase Protease Complexes in Neurodegeneration, Cancer and Immunity

A. De, J. McCarthy, Caroline Coleman-Vaughan, 2017 .

Loss of Presenilin 2 Function Is Associated with Defective LPS-Mediated Innate Immune Responsiveness

V. Agrawal, N. Sawhney, J. McCarthy, 2016, Molecular Neurobiology.

Presenilin-dependent regulated intramembrane proteolysis and γ-secretase activity

J. McCarthy, C. Twomey, P. Wujek, 2009, Cellular and Molecular Life Sciences.

Regulated intramembrane proteolysis, innate immunity and therapeutic targets in Alzheimer's disease

J. McCarthy, Caroline Coleman-Vaughan, Tara Hurst, 2016 .

In Silico Identification of Potential Phosphorylation in the Cytoplasmic Domain of Epithelial Cell Adhesion Molecule

A. De, J. McCarthy, Arjun Ray, 2020, ACS omega.

Increased resistance to apoptosis associated with HL-60 myeloid differentiation status.

J. McCarthy, R. S. Fernandes, T. G. Gotter, 1994, Anticancer Research.

Gamma-secretase-independent role for cadherin-11 in neurotrophin receptor p75 (p75NTR) mediated glioblastoma cell migration

John Macsharry, Janina Berghoff, Anirudh Vinay Jaisimha, 2015, Molecular and Cellular Neuroscience.

Presenilin‐1 is an unprimed glycogen synthase kinase‐3β substrate

J. McCarthy, C. Twomey, 2006, FEBS letters.

γ-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling*

James C. Powell, V. Agrawal, Jyoti Chhibber-Goel, 2016, The Journal of Biological Chemistry.

Structural and functional characterization of the upstream regulatory region of the human gene encoding prostate apoptosis response factor-4.

S. Hsu, F. Kirschenbaum, J. McCarthy, 2002, Gene.

The insulin-like growth factor 1 (IGF-1) receptor is a substrate for gamma-secretase-mediated intramembrane proteolysis.

James C. Powell, J. McCarthy, Brian McElroy, 2007, Biochemical and biophysical research communications.

Semagacestat, a γ‐secretase inhibitor, activates the growth hormone secretagogue (GHS‐R1a) receptor

T. Dinan, J. Cryan, H. Schellekens, 2013, The Journal of pharmacy and pharmacology.

Oxygen-18 isotope exchange and equilibration processes over preoxidised and promoted ceria. Part I. 15N18O(g) or (18O2+16O2(g))

J. McCarthy, C. Gibson, J. Cunningham, 1999 .

A ubiquitin‐binding CUE domain in presenilin‐1 enables interaction with K63‐linked polyubiquitin chains

J. McCarthy, Run Yan, Stephen Duggan, 2015, FEBS letters.

Interleukin-1 Receptor Type 1 Is a Substrate for γ-Secretase-dependent Regulated Intramembrane Proteolysis*

James C. Powell, Baukje M. Elzinga, J. McCarthy, 2009, Journal of Biological Chemistry.

Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.

S. Hsu, F. Kirschenbaum, J. McCarthy, 2001, The Journal of biological chemistry.

Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels.

F. Kirschenbaum, J. McCarthy, B. Cordell, 2001, Journal of Biological Chemistry.