D. Chaudhary

发表

Natural killer cells from protein kinase C θ−/− mice stimulated with interleukin‐12 are deficient in production of interferon‐γ

K. Page, S. Goldman, K. Page, 2008, Journal of leukocyte biology.

First generation 5-vinyl-3-pyridinecarbonitrile PKCtheta inhibitors.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and PKCtheta inhibitory activity of a series of 5-vinyl phenyl sulfonamide-3-pyridinecarbonitriles.

D. Boschelli, C. Eid, Julie Lee, 2009, Bioorganic & medicinal chemistry letters.

Recent advances in the discovery of small molecule inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4) as a therapeutic target for inflammation and oncology disorders.

S. Robinson, D. Romero, D. Chaudhary, 2015, Journal of medicinal chemistry.

MYD88 L265P mutations identify a prognostic gene expression signature and a pathway for targeted inhibition in CLL

S. Kasar, S. Fernandes, Jennifer R. Brown, 2018, British journal of haematology.

Synthesis and PKCtheta inhibitory activity of a series of 4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2008, Bioorganic & medicinal chemistry letters.

Mitigation of Septic Signs by Pravastatin during LPS Co-Administered Hen-Egg White Lysozyme Immunization in Mice

K. Dhama, M. Wani, Rajendra Singh, 2014 .

Targeting protein kinase C-θ for asthma

D. Boschelli, M. Kasaian, D. Chaudhary, 2010 .

IL-33 synergizes with IgE-dependent and IgE-independent agents to promote mast cell and basophil activation

A. Margulis, S. Goldman, M. Kasaian, 2010, Inflammation Research.

Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma.

Carissa M Krane, S. Goldman, C. Krane, 2009, Cytokine.

Synthesis of 3-Farnesyl Salicylic Acid a Novel Antimicrobial from Piper multiplinervium

F. Liu, G. Phillips, G. Kraus, 2013, Natural product communications.

Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCtheta inhibitors.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and PKCtheta inhibitory activity of a series of 4-indolylamino-5-phenyl-3-pyridinecarbonitriles.

D. Boschelli, A. Wissner, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

Second generation 4-(4-methyl-1H-indol-5-ylamino)-2-phenylthieno[2,3-b]pyridine-5-carbonitrile PKCtheta inhibitors.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

2-Alkenylthieno[2,3-b]pyridine-5-carbonitriles: Potent and selective inhibitors of PKCtheta.

D. Boschelli, Julie Lee, D. Chaudhary, 2008, Bioorganic & medicinal chemistry letters.

Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitors.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2010, Bioorganic & medicinal chemistry letters.

C-5 Substituted heteroaryl 3-pyridinecarbonitriles as PKCtheta inhibitors: Part I.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

Purification and characterization of Cyclophilin: a protein associated with protein folding in Salmonella Typhimurium

M. Kumawat, S. Shubham, D. K. Sarma, 2021, Archives of Microbiology.

A Flexible Synthesisof Indoles from ortho-Substituted Anilines: ADirect Synthesis of Isocryptolepine

Haitao Guo, G. Kraus, D. Chaudhary, 2010 .

PD‐1 inhibits T‐cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθ

K. Sheppard, J. Jussif, L. Fitz, 2004 .

Nitromethyl benzoate annulation reactions: a rapid construction of the stealthin skeleton

G. Kraus, D. Chaudhary, Yi Yuan, 2012 .

An alternate use of Calotropis gigantea: biomethanation.

D. Chaudhary, P. Shilpkar, M. Shah, 2007 .

PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta.

K. Sheppard, L. Carter, J. Jussif, 2004, FEBS letters.

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

G. Freeman, T. Okazaki, T. Honjo, 2001, Nature Immunology.

Proteome Organization of COVID-19: Illustrating Targets for Vaccine Development

A. Bharadwaj, D. Chaudhary, A. Saxena, 2020 .

Role of CED-4 in the activation of CED-3

E. Koonin, A. Chinnaiyan, V. Dixit, 1997, Nature.

Catalytic Domain Crystal Structure of Protein Kinase C-θ (PKCθ)*♦

Rita Greco, Diane Joseph-McCarthy, L. Mosyak, 2004, Journal of Biological Chemistry.

Clinical Outcome in Patient Undergoing LSCS via ERAS Pathway versus Traditional Pathway: A Prospective Observational Study

D. Chaudhary, Bhamini Jakhetiya, A. Gupta, 2022, The Journal of Obstetrics and Gynecology of India.

Selective interleukin-1 receptor–associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy

L. Staudt, A. Shaffer, L. Rui, 2015, The Journal of experimental medicine.

The Death Inhibitory Molecules CED-9 and CED-4L Use a Common Mechanism to Inhibit the CED-3 Death Protease*

A. Chinnaiyan, V. Dixit, K. O'rourke, 1998, The Journal of Biological Chemistry.

Root-Knot Nematode, Meloidogyne incognita and Salicyclic Acid Induce Production of PR-Proteins in Tomato

Pankaj, A. Sirohi, D. Chaudhary, 2008 .

IRAK4 Kinase As A Novel Therapeutic Target in the ABC Subtype of Diffuse Large B Cell Lymphoma

L. Staudt, K. Lim, S. Robinson, 2012 .

Characterization of protein kinase C theta activation loop autophosphorylation and the kinase domain catalytic mechanism.

R. Kriz, M. Stahl, A. Aulabaugh, 2005, Biochemistry.

The c-myc promoter binding protein (MBP-1) and TBP bind simultaneously in the minor groove of the c-myc P2 promoter.

D. Chaudhary, D. Miller, 1995, Biochemistry.

In vitro And In vivo Immunomodulating Properties of Mesenchymal Stem Cells.

R. Khandia, T. Goswami, A. Munjal, 2018, Recent patents on inflammation & allergy drug discovery.

PKCtheta: A potential therapeutic target for T-cell-mediated diseases.

M. Kasaian, D. Chaudhary, 2006, Current opinion in investigational drugs.

Effect Of MYD88 Mutation In CLL On IRAK4 and BTK Inhibition In Vitro

N. Pochet, D. Neuberg, R. Improgo, 2013 .

Conversion of substituted benzyl ethers to diarylmethanes. A direct synthesis of diarylbenzofurans

G. Kraus, D. Chaudhary, 2012 .

Structure-based optimization of PKCθ inhibitors

L. Mosyak, D. Joseph-McCarthy, W. Somers, 2007 .

Identification, characterization and initial hit-to-lead optimization of a series of 4-arylamino-3-pyridinecarbonitrile as protein kinase C theta (PKCtheta) inhibitors.

D. Joseph-McCarthy, A. Wissner, J. Ellingboe, 2008, Journal of medicinal chemistry.

Structure-based optimization of PKCtheta inhibitors.

L. Mosyak, D. Joseph-McCarthy, W. Somers, 2007, Biochemical Society Transactions.