Z. Zsengellér

发表

Macrophage Migration Inhibitory Factor as a Novel Biomarker of Portopulmonary Hypertension

R. Thadhani, S. Karumanchi, H. DuBrock, 2016, Pulmonary circulation.

Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice.

J. Whitsett, B. Trapnell, Xiaoyun Hu, 1995, Human gene therapy.

Indices of Apoptosis Activation After Blood Cardioplegia and Cardiopulmonary Bypass

F. Sellke, C. Szabó, R. Clements, 2006, Circulation.

Complement 7 Is Up-Regulated in Human Early Diabetic Kidney Disease.

T. Libermann, M. Selig, R. Thadhani, 2018, The American journal of pathology.

Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease

I. Stillman, D. Friedman, M. Pollak, 2021, Disease models & mechanisms.

Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia–reperfusion: Therapeutic potential of mitochondrially targeted antioxidants

K. Erdélyi, L. Liaudet, J. Joseph, 2012, Free radical biology & medicine.

Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst

J. Groves, C. Szabó, I. Obrosova, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Gender Differences in the Endotoxin-Induced Inflammatory and Vascular Responses: Potential Role of Poly(ADP-ribose) Polymerase Activation

K. Murthy, C. Szabó, M. Kollai, 2005, Journal of Pharmacology and Experimental Therapeutics.

Poly(ADP-Ribose) Polymerase Promotes Cardiac Remodeling, Contractile Failure, and Translocation of Apoptosis-Inducing Factor in a Murine Experimental Model of Aortic Banding and Heart Failure

C. Szabó, M. Kollai, L. Kiss, 2005, Journal of Pharmacology and Experimental Therapeutics.

Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.

C. Szabó, M. Yorek, M. Stevens, 2005, Diabetes.

Adenovirus infection increases iNOS and peroxynitrite production in the lung.

B. Trapnell, C. Szabó, J. Whitsett, 2001, American journal of physiology. Lung cellular and molecular physiology.

The oxidation state of cysteine thiols on the ectodomain of TLR2 and TLR4 influences intracellular signaling.

N. Gerard, Z. Zsengellér, 2019, Immunobiology.

with matrix metalloproteinase expression and emphysema colony-stimulating factor is spontaneously corrected with age and associated Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage

B. Trapnell, Y. Shibata, N. Palaniyar, 2013 .

Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema.

B. Trapnell, Y. Shibata, N. Palaniyar, 2001, Blood.

Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat

C. Szabó, V. Besson, M. Plotkine, 2005, Brain Research.

Inhibition of poly(ADP-ribose)polymerase (PARP) by INO-1001 attenuates ovine acute lung injury in an ovine model of sepsis following smoke inhalation injury

C. Szabó, L. Traber, D. Traber, 2003 .

Pharmacological Inhibition of CB 1 Cannabinoid Receptor Protects Against Doxorubicin-Induced Cardiotoxicity

L. Liaudet, G. Haskó, P. Pacher, 2007 .

Potential role of poly(adenosine 5′-diphosphate-ribose) polymerase activation in the pathogenesis of myocardial contractile dysfunction associated with human septic shock

P. Lotufo, C. Szabó, E. Caldini, 2006, Critical care medicine.

Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes

S. Ito, A. Fukamizu, Masayuki Yamamoto, 2017, Science Signaling.

Renal PGC1α May Be Associated with Recovery after Delayed Graft Function

M. Pavlakis, I. Stillman, S. Parikh, 2017, Nephron.

Excess placental secreted frizzled-related protein 1 in maternal smokers impairs fetal growth.

S. Salahuddin, S. Karumanchi, J. Hecht, 2015, The Journal of clinical investigation.

Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia.

Christopher D. Clark, P. Kang, S. Karumanchi, 2016, The Journal of clinical investigation.

Alveolar Macrophages by GM-CSF and PU.1 Organization Are Coordinately Regulated in Nonspecific Phagocytosis, and Cytoskeletal Endocytic Internalization of Adenovirus,

J. Whitsett, B. Trapnell, Y. Shibata, 2002 .

Adenovirus-mediated granulocyte-macrophage colony-stimulating factor improves lung pathology of pulmonary alveolar proteinosis in granulocyte-macrophage colony-stimulating factor-deficient mice.

J. Whitsett, A. Levine, C. Bachurski, 1998, Human gene therapy.

GM-CSF enhances lung growth and causes alveolar type II epithelial cell hyperplasia in transgenic mice.

G. Dranoff, J. Whitsett, S. Wert, 1997, American journal of physiology. Lung cellular and molecular physiology.

GM-CSF enhances lung growth and causes alveolar type II epithelial cell hyperplasia in transgenic mice.

G. Dranoff, J. Whitsett, S. Wert, 1997, American journal of physiology. Lung cellular and molecular physiology.

AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis.

S. Salahuddin, S. Karumanchi, K. Gray, 2019, The American journal of pathology.

Placental lesions of vascular insufficiency are associated with anti-angiogenic state in women with preeclampsia

S. Salahuddin, R. Thadhani, S. Karumanchi, 2014, Hypertension in pregnancy.

Transcriptionally Active Syncytial Aggregates in the Maternal Circulation May Contribute to Circulating Soluble Fms-Like Tyrosine Kinase 1 in Preeclampsia

S. Karumanchi, A. Jeyabalan, C. Hubel, 2012, Hypertension.

PGC 1 α-dependent NAD biosynthesis links oxidative metabolism to renal protection Citation

C. Clish, A. Berg, E. Rhee, 2022 .

Total Versus Free Placental Growth Factor Levels in the Pathogenesis of Preeclampsia

S. Salahuddin, R. Thadhani, S. Karumanchi, 2020, Hypertension.

Trophoblast mitochondrial function is impaired in preeclampsia and correlates negatively with the expression of soluble fms-like tyrosine kinase 1.

S. Salahuddin, I. Stillman, S. Rana, 2016, Pregnancy hypertension.

Hydrogen sulfide attenuates sFlt1-induced hypertension and renal damage by upregulating vascular endothelial growth factor.

P. Kang, H. van Goor, S. Karumanchi, 2014, Journal of the American Society of Nephrology : JASN.

Cisplatin Nephrotoxicity Involves Mitochondrial Injury with Impaired Tubular Mitochondrial Enzyme Activity

S. Karumanchi, B. Kalyanaraman, I. Stillman, 2012, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.

G. Seigel, C. Szabó, M. Stevens, 2004, International journal of molecular medicine.

Internalization of Adenovirus by Alveolar Macrophages Initiates Early Proinflammatory Signaling during Acute Respiratory Tract Infection

B. Trapnell, Z. Zsengellér, P. Berclaz, 2000, Journal of Virology.

Recombinant adenoviral vector disrupts surfactant homeostasis in mouse lung.

B. Trapnell, J. Whitsett, C. Bachurski, 1997, Human gene therapy.

ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor-Induced Thrombotic Microangiopathy.

D. Wagner, S. Karumanchi, I. Stillman, 2016, Journal of the American Society of Nephrology : JASN.

Poly(ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation.

S. Hagl, C. Flechtenmacher, C. Szabó, 2005, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Activation of Poly(ADP-Ribose) Polymerase by Myocardial Ischemia and Coronary Reperfusion in Human Circulating Leukocytes

I. Préda, K. Murthy, C. Szabó, 2006, Molecular medicine.

Soluble fms-Like Tyrosine Kinase 1 Localization in Renal Biopsies of CKD

S. Karumanchi, S. Rosen, M. Tavasoli, 2019, Kidney international reports.

Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes.

S. Salahuddin, S. Karumanchi, J. Hecht, 2017, Placenta.

PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model

D. Wagner, S. Karumanchi, L. Erpenbeck, 2016, Biology of reproduction.

[56-OR]: Placental lesions of vascular insufficiency are associated with anti-angiogenic state in women with preeclampsia

S. Salahuddin, R. Thadhani, S. Karumanchi, 2015 .

Placental Origins of Angiogenic Dysfunction in Mirror Syndrome

K. Lim, I. Stillman, C. Zelop, 2012, Hypertension in pregnancy.

Placental expression of angiogenic factors in Trisomy 13.

K. Lim, B. Cohen, S. Karumanchi, 2011, American journal of obstetrics and gynecology.

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance

M. Bhasin, C. Brooks, T. Finkel, 2019, JCI insight.

The Use of Cytochrome C Oxidase Enzyme Activity and Immunohistochemistry in Defining Mitochondrial Injury in Kidney Disease

S. Rosen, Z. Zsengellér, 2016, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The pathology of eclampsia: An autopsy series

J. Ordi, S. Karumanchi, S. Rosen, 2017, Hypertension in pregnancy.

Hypertensive Disorders of Pregnancy : Effects on Mother and Baby Exposure to placental ischemia impairs postpartum maternal renal and cardiac function in rats

A. Franx, M. Verhaar, J. Granger, 2017 .

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance

M. Bhasin, C. Brooks, T. Finkel, 2020, JCI insight.

University of Groningen Hydrogen Sulfide in Preeclampsia

P. Kang, S. Karumanchi, I. Stillman, 2015 .

Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly(ADP-ribose) polymerase-1.

C. Szabó, Z. Zsengellér, Chunyang Xiao, 2004, Cardiovascular research.

Role of poly(ADP-ribose) polymerase activation in the pathogenesis of cardiopulmonary dysfunction in a canine model of cardiopulmonary bypass.

S. Hagl, C. Flechtenmacher, C. Szabó, 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Down-regulation of soluble fms-like tyrosine kinase 1 expression in invasive placentation

S. Karumanchi, J. Hecht, M. Hacker, 2017, Archives of Gynecology and Obstetrics.

Methylmalonic acidemia: A megamitochondrial disorder affecting the kidney

C. Venditti, L. Teot, G. Berry, 2014, Pediatric Nephrology.

Congenital chloride-losing diarrhea in a Mexican child with the novel homozygous SLC26A3 mutation G393W

Bai-Lin Wu, S. Alper, W. Lencer, 2015, Front. Physiol..

Inhibition of Poly (ADP-ribose) Polymerase Attenuates Acute Lung Injury in an Ovine Model of Sepsis

C. Szabó, L. Traber, D. Traber, 2004, Shock.

Mesenteric injury after cardiopulmonary bypass: Role of poly(adenosine 5′-diphosphate-ribose) polymerase*

S. Hagl, C. Flechtenmacher, C. Szabó, 2004, Critical care medicine.

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice.

M. Bhasin, D. Burstein, A. Kher, 2011, The Journal of clinical investigation.

PGC1α-dependent NAD biosynthesis links oxidative metabolism to renal protection

M. Bhasin, C. Clish, A. Berg, 2016, Nature.

Mitochondrial‐targeted antioxidants represent a promising approach for prevention of cisplatin‐induced nephropathy

J. Joseph, B. Kalyanaraman, I. Stillman, 2012, Free radical biology & medicine.

RNAi Modulation of Placental sFLT1 for the Treatment of Preeclampsia.

M. Moore, A. Khvorova, Andrew H Coles, 2018, Nature Biotechnology.

Keratinocyte growth factor stimulates transduction of the respiratory epithelium by retroviral vectors.

C. Halbert, A. Miller, J. Whitsett, 1999, Human gene therapy.

Transcriptional Patterns in Peritoneal Tissue of Encapsulating Peritoneal Sclerosis, a Complication of Chronic Peritoneal Dialysis

N. Braun, M. Bhasin, S. Alper, 2013, PloS one.

Loss of kAE1 expression in collecting ducts of end-stage kidneys from a family with SLC4A1 G609R-associated distal renal tubular acidosis

S. Alper, B. Shmukler, Z. Zsengellér, 2016, Clinical kidney journal.

Loss of kAE 1 expression in collecting ducts of end-stage kidneys from a family with SLC 4 A 1 G 609 R-associated distal renal tubular acidosis

S. Alper, B. Shmukler, Z. Zsengellér, 2016 .

Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity.

L. Liaudet, P. Pacher, S. Batkai, 2007, Journal of the American College of Cardiology.

Angiotensin II-Mediated Endothelial Dysfunction: Role of Poly(ADP-ribose) Polymerase Activation

C. Szabó, M. Kollai, P. Pacher, 2004, Molecular medicine.

Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle.

P. Rustin, L. Goodyear, M. Hirshman, 2013, Cell reports.

Poly(Adenosine diphosphate-ribose) polymerase inhibition preserves erectile function in rats after cavernous nerve injury.

W. Hellstrom, C. Szabó, T. Bivalacqua, 2005, The Journal of urology.

Endocytic Internalization of Adenovirus, Nonspecific Phagocytosis, and Cytoskeletal Organization Are Coordinately Regulated in Alveolar Macrophages by GM-CSF and PU.11

J. Whitsett, B. Trapnell, Y. Shibata, 2002, The Journal of Immunology.

Placental sFLT1 is associated with complement activation and syncytiotrophoblast damage in preeclampsia

S. Salahuddin, S. Karumanchi, Z. Zsengellér, 2019, Hypertension in pregnancy.

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells.

L. Rossetti, T. Matsumura, M. Brownlee, 2003, The Journal of clinical investigation.

A paradoxical protective role for the proinflammatory peptide substance P receptor (NK1R) in acute hyperoxic lung injury.

A. Mitsialis, B. Lu, C. Gerard, 2009, American journal of physiology. Lung cellular and molecular physiology.

Revisiting decidual vasculopathy.

S. Karumanchi, S. Rosen, J. Hecht, 2016, Placenta.

production in the lung Adenovirus infection increases iNOS and peroxynitrite

B. Trapnell, C. Szabó, G. Ross, 2013 .

Disruption of Renal Arginine Metabolism Promotes Kidney Injury in Hepatorenal Syndrome in Mice

K. Erdélyi, I. Stillman, B. Németh, 2018, Hepatology.

Anti-T cell receptor antibody prolongs transgene expression and reduces lung inflammation after adenovirus-mediated gene transfer.

G. Boivin, B. Trapnell, J. Whitsett, 1997, Human gene therapy.

Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase.

S. Cuzzocrea, B. Zingarelli, C. Szabó, 1997, Cardiovascular research.

Quantification of PARP activity in human tissues: ex vivo assays in blood cells and immunohistochemistry in human biopsies.

C. Szabó, E. Horváth, Z. Zsengellér, 2011, Methods in molecular biology.

HNF4α mediated QPRT expression in the kidney facilitates resilience against acute kidney injury

A. Takakura, Huihui Huang, Vamsidhara Vemireddy, 2023, bioRxiv.

Poly(ADP-Ribose) Polymerase Contributes to the Development of Myocardial Infarction in Diabetic Rats and Regulates the Nuclear Translocation of Apoptosis-Inducing Factor

C. Szabó, Z. Zsengellér, Min Chen, 2004, Journal of Pharmacology and Experimental Therapeutics.

A mouse model of placenta accreta spectrum.

S. Karumanchi, Z. Zsengellér, S. Burke, 2020, Placenta.

Smooth Muscle Mineralocorticoid Receptor Promotes Hypertension After Preeclampsia

Nicholas D. Camarda, E. Seely, I. Jaffe, 2023, Circulation research.

Poly-ADP-Ribose Polymerase Inhibition Reduces Mesenteric Injury after Cardiopulmonary Bypass*

S. Hagl, C. Flechtenmacher, C. Szabó, 2004, The Thoracic and cardiovascular surgeon.

864 Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury

H. Denk, R. Zenz, M. Trauner, 2003 .

Nitroxide—HMP—Protects Human Trophoblast HTR-8/SVneo Cells from H2O2-Induced Oxidative Stress by Reducing the HIF1A Signaling Pathway

S. Salahuddin, Z. Zsengellér, M. Török, 2023, Antioxidants.

Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies.

C. Szabó, E. Horváth, Z. Zsengellér, 2017, Methods in molecular biology.

Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy.

J. Joseph, B. Kalyanaraman, P. Pacher, 2012, Free radical biology & medicine.