M. Kajino

发表

BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression.

H. Oki, M. Takizawa, S. Tanida, 2010, Chemistry & biology.

High-Throughput Screening of Potassium-Competitive Acid Blockers

A. Hasuoka, M. Kajino, N. Inatomi, 2012, Journal of biomolecular screening.

BTZO-15, an ARE-Activator, Ameliorates DSS- and TNBS-Induced Colitis in Rats

M. Takizawa, Yoshimi Sato, T. Imaeda, 2011, PloS one.

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2).

Toshimasa Tanaka, T. Kawamoto, M. Yamaguchi, 2008, Bioorganic & medicinal chemistry.

1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438), a Novel and Potent Potassium-Competitive Acid Blocker for the Treatment of Acid-Related Diseases

M. Kajino, Y. Tsukimi, N. Inatomi, 2010, Journal of Pharmacology and Experimental Therapeutics.

Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB).

Terufumi Takagi, Terufumi Takagi, Teruki Hamada, 2012, Journal of medicinal chemistry.

The Hantzsch Synthesis with 6-Aminouracils: One Step Synthesis of Pyrido[2,3-d]pyrimidines

M. Kajino, K. Meguro, 1990 .

Synthesis and biological activities of new 2-substituted 1,4-benzoxazine derivatives.

M. Kajino, K. Meguro, Y. Shibouta, 1991, Chemical & pharmaceutical bulletin.

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-ones as potassium-competitive acid blockers.

Terufumi Takagi, T. Imaeda, F. Itoh, 2017, Bioorganic & medicinal chemistry.

Synthesis and biological activities of new 1,4-benzothiazine derivatives.

M. Kajino, K. Meguro, H. Tawada, 1991, Chemical & pharmaceutical bulletin.

Efficient Synthesis of Branched Propargyl- and Allylsilanes

L. Tietze, M. Kajino, T. Neumann, 1995 .

Synthesis and biological activities of optical isomers of 2-(4-diphenylmethyl-1-piperazinyl)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate (manidipine) dihydrochloride.

A. Nagaoka, M. Kajino, K. Meguro, 1989, Chemical & pharmaceutical bulletin.

Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers.

Terufumi Takagi, A. Hasuoka, M. Kajino, 2012, Bioorganic & medicinal chemistry.

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action.

Teruki Hamada, T. Imaeda, F. Itoh, 2017, Bioorganic & medicinal chemistry.

A Study Comparing the Antisecretory Effect of TAK-438, a Novel Potassium-Competitive Acid Blocker, with Lansoprazole in Animals

M. Kajino, T. Takeuchi, N. Inatomi, 2011, Journal of Pharmacology and Experimental Therapeutics.

BTZO-2, an antioxidant response element-activator, provides protection against lethal endotoxic shock in mice.

M. Takizawa, S. Tanida, Yoshimi Sato, 2013, European journal of pharmacology.

A comparative study on the modes of action of TAK-438, a novel potassium-competitive acid blocker, and lansoprazole in primary cultured rabbit gastric glands.

M. Kajino, N. Inatomi, Jun Matsukawa, 2011, Biochemical pharmacology.

monofumarate (TAK-438), A Novel and Potent Potassium-Competitive Acid Blocker for the Treatment of Acid-Related Diseases. Authors

M. Kajino, Y. Tsukimi, N. Inatomi, 2010 .

Synthetic studies of five-membered heteroaromatic derivatives as potassium-competitive acid blockers (P-CABs).

Terufumi Takagi, A. Hasuoka, F. Itoh, 2015, Bioorganic & medicinal chemistry letters.

, a novel P-CAB

M. Kajino, Y. Tsukimi, Nobuhiro Inatomi, 2010 .