G. Honda

发表

The fifth epidermal growth factor like region of thrombomodulin alleviates LPS-induced sepsis through interacting with GPR15

T. Ikezoe, C. Nishioka, A. Yokoyama, 2017, Thrombosis and Haemostasis.

Thrombomodulin enhances the antifibrinolytic and antileukemic effects of all-trans retinoic acid in acute promyelocytic leukemia cells.

T. Ikezoe, Jing Yang, C. Nishioka, 2012, Experimental hematology.

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

S. Sugano, Yutaka Suzuki, E. Nishida, 2003, Oncogene.

A case of thrombomodulin mutation causing defective thrombin binding with absence of protein C and TAFI activation.

Tatsuya Hayashi, J. Nishioka, N. Akita, 2020, Blood advances.

Hypofibrinogenemia is Associated With a High Degree of Risk in Infectious and Hematological Diseases: A Post-Hoc Analysis of Post-Marketing Surveillance of Patients With Disseminated Intravascular Coagulation Treated With Thrombomodulin Alfa

S. Madoiwa, T. Ikezoe, T. Iba, 2020 .

LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin.

M. Shimaoka, Koji Suzuki, H. Imai, 2016, Biochemical and biophysical research communications.

The Fifth Epidermal Growth Factor-like Region of Thrombomodulin Alleviates Murine Graft-versus-Host Disease in a G-Protein Coupled Receptor 15 Dependent Manner.

T. Ikezoe, C. Nishioka, A. Yokoyama, 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Thrombomodulin alfa treatment in patients with acute promyelocytic leukemia and disseminated intravascular coagulation: a retrospective analysis of an open-label, multicenter, post-marketing surveillance study cohort.

J. Mimuro, Y. Sakata, I. Kitajima, 2014, Thrombosis research.

Effects of thrombomodulin alfa on hemostatic parameters in disseminated intravascular coagulation: Post hoc analysis of a phase 3 randomized controlled trial

Takashi Ito, I. Maruyama, N. Aikawa, 2020, Research and practice in thrombosis and haemostasis.

Large-scale identification and characterization of human genes that activate NF-κB and MAPK signaling pathways

S. Sugano, Yutaka Suzuki, E. Nishida, 2003, Oncogene.

Human soluble thrombomodulin-induced blockade of peripheral HMGB1-dependent allodynia in mice requires both the lectin-like and EGF-like domains.

R. Tsujita, A. Kawabata, F. Sekiguchi, 2018, Biochemical and biophysical research communications.

Hypofibrinogenemia is associated with a high degree of risk in infectious diseases: a post-hoc analysis of post-marketing surveillance of patients with disseminated intravascular coagulation treated with thrombomodulin alfa

S. Madoiwa, T. Ikezoe, T. Iba, 2021, Thrombosis Journal.

Severe Antithrombin Deficiency May be Associated With a High Risk of Pathological Progression of DIC With Suppressed Fibrinolysis

S. Madoiwa, T. Ikezoe, T. Iba, 2020, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Post-marketing surveillance of thrombomodulin alfa, a novel treatment of disseminated intravascular coagulation - safety and efficacy in 1,032 patients with hematologic malignancy.

J. Mimuro, Y. Sakata, I. Kitajima, 2014, Thrombosis research.

The fifth epidermal growth factor-like region of thrombomodulin exerts cytoprotective function and prevents SOS in a murine model

M. Furihata, T. Ikezoe, C. Nishioka, 2017, Bone Marrow Transplantation.

An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells

Tatsuya Hayashi, Koji Suzuki, G. Honda, 1992 .

G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin

T. Ikezoe, C. Nishioka, A. Yokoyama, 2017, Scientific Reports.

Sepsis-Associated DIC with Decreased Levels of Antithrombin and Fibrinogen is the Target for Combination Therapy with Thrombomodulin Alfa and Antithrombin

S. Madoiwa, T. Ikezoe, T. Iba, 2022, TH Open.

Specific detection of high mobility group box 1 degradation product with a novel ELISA

S. Yamada, Takashi Ito, I. Maruyama, 2021, Molecular medicine.

Clinical Features of Disseminated Intravascular Coagulation According to the French-American-British Classification in Patients With Acute Leukemia and Thrombomodulin Alfa Treatment—A Cohort Study Using a Postmarketing Surveillance Database

S. Madoiwa, K. Kawasugi, G. Honda, 2021, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Postmarketing Surveillance of Recombinant Human Soluble Thrombomodulin (Thrombomodulin α) in Pediatric Patients With Disseminated Intravascular Coagulation

J. Mimuro, Y. Sakata, A. Shirahata, 2014, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Pediatric Patients With Disseminated Intravascular Coagulation ) in α Postmarketing Surveillance of Recombinant Human Soluble Thrombomodulin ( Thrombomodulin

J. Mimuro, Y. Sakata, A. Shirahata, 2014 .

Recombinant soluble human thrombomodulin (thrombomodulin alfa) in the treatment of neonatal disseminated intravascular coagulation

J. Mimuro, Y. Sakata, A. Shirahata, 2014, European Journal of Pediatrics.

Surveillance of the safety and efficacy of recombinant human soluble thrombomodulin in patients with obstetrical disseminated intravascular coagulation.

M. Kajiki, G. Honda, Takao Kobayashi, 2017, Thrombosis Research.

An evaluation of the Japanese Society on Thrombosis and Hemostasis criteria for disseminated intravascular coagulation as a predictor of prognosis in patients with infection

S. Madoiwa, T. Ikezoe, H. Wada, 2021, International journal of laboratory hematology.

Thrombomodulin-induced differentiation of acute myelomonocytic leukemia cells via JNK signaling.

T. Ikezoe, Jing Yang, C. Nishioka, 2012, Leukemia research.

Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain

T. Ikezoe, Kailin Xu, L. Zeng, 2018, Haematologica.

Thrombomodulin Protects Endothelial Cells From a Calcineurin Inhibitor–Induced Cytotoxicity by Upregulation of Extracellular Signal–Regulated Kinase/Myeloid Leukemia Cell-1 Signaling

M. Furihata, T. Ikezoe, Jing Yang, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Benefit Profile of Thrombomodulin Alfa Combined with Antithrombin Concentrate in Patients with Sepsis-Induced Disseminated Intravascular Coagulation

T. Yamane, Y. Eguchi, G. Honda, 2022, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

A Thrombomodulin Promoter Gene Polymorphism, rs2239562, Influences Both Susceptibility to and Outcome of Sepsis

M. Hatano, Teruo Sakamoto, O. Takasu, 2022, Frontiers in Medicine.

A Japanese Family Meeting the Clinical Diagnostic Criteria for MEN1 with a MEN1 Variant of Uncertain Significance

K. Nakashima, S. Nishimura, H. Ishiwatari, 2023, Internal medicine.

G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin

T. Ikezoe, C. Nishioka, A. Yokoyama, 2017, Scientific Reports.