Ajit K. Parhi

发表

Phenyl substituted 3-hydroxypyridin-2(1H)-ones: inhibitors of influenza A endonuclease.

E. Arnold, E. LaVoie, K. Das, 2013, Bioorganic & medicinal chemistry.

3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease.

E. Arnold, E. LaVoie, K. Das, 2013, ACS medicinal chemistry letters.

In vivo studies of the SERT-selective [18F]FPBM and VMAT2-selective [18F]AV-133 radiotracers in a rat model of Parkinson's disease.

H. Kung, C. Hou, B. Lieberman, 2010, Nuclear medicine and biology.

TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus

M. Weinstein, E. LaVoie, D. S. Pilch, 2015, Antimicrobial Agents and Chemotherapy.

In Vivo Pharmacodynamic Evaluation of an FtsZ Inhibitor, TXA-709, and Its Active Metabolite, TXA-707, in a Murine Neutropenic Thigh Infection Model

D. Andes, K. Marchillo, A. Lepak, 2015, Antimicrobial Agents and Chemotherapy.

Inhibition of RND-type efflux pumps confers the FtsZ-directed prodrug TXY436 with activity against Gram-negative bacteria.

E. LaVoie, D. S. Pilch, M. Kaul, 2014, Biochemical pharmacology.

Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes.

E. LaVoie, D. S. Pilch, Songfeng Lu, 2013, European journal of medicinal chemistry.

An FtsZ-Targeting Prodrug with Oral Antistaphylococcal Efficacy In Vivo

E. LaVoie, D. S. Pilch, M. Kaul, 2013, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and in vivo antistaphylococcal efficacy of TXY541, a 1-methylpiperidine-4-carboxamide prodrug of PC190723.

E. LaVoie, D. S. Pilch, M. Kaul, 2013, Biochemical pharmacology.

Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines.

E. LaVoie, D. S. Pilch, M. Kaul, 2013, Bioorganic & medicinal chemistry letters.

Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents.

E. LaVoie, D. S. Pilch, M. Kaul, 2013, Bioorganic & medicinal chemistry letters.

Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives.

E. LaVoie, D. S. Pilch, Songfeng Lu, 2012, Bioorganic & medicinal chemistry letters.

3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents.

E. LaVoie, D. S. Pilch, M. Kaul, 2012, Bioorganic & medicinal chemistry.

TXA497 as a topical antibacterial agent: comparative antistaphylococcal, skin deposition, and skin permeation studies with mupirocin.

E. LaVoie, D. S. Pilch, M. Kaul, 2014, International journal of pharmaceutics.

Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in Pseudomonas aeruginosa

P. Datta, Yanlu Cao, Yongzhen Zhang, 2022, Antibiotics.

2-(2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)-phenylthio)benzenamine derivatives as serotonin transporter imaging agents.

H. Kung, M. Kung, S. Choi, 2007, Journal of medicinal chemistry.

Novel MreB inhibitors with antibacterial activity against Gram (-) bacteria

E. LaVoie, D. S. Pilch, Yanlu Cao, 2022, Medicinal Chemistry Research.

Medium effects on the reactions of coordination complexes: Base hydrolysisof(αβS)(p-hydroxybenzoato)(tetraethylenepentamine) cobalt(III) in iso-propanol–water, tert-butanol–water and dimethyl sulfoxide–water media

Ajit K. Parhi, G. Pradhan, 1998 .

Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives.

E. LaVoie, D. S. Pilch, M. Kaul, 2012, Bioorganic & medicinal chemistry letters.

A Weinreb nitrile oxide and nitrone for cycloaddition.

R. Franck, Ajit K. Parhi, 2004, Organic letters.

Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ.

E. LaVoie, D. S. Pilch, E. Mizohata, 2017, ACS chemical biology.

Medium effect on the reactions of complexes: kinetics and mechanism of the base hydrolysis of cis-[(salicylato)(amine)bis(ethylenediamine)cobalt(III)] compounds in methanol-water

Ajit K. Parhi, G. Pradhan, P. Mohanty, 1996 .

Combination with a FtsZ inhibitor potentiates the in vivo efficacy of oxacillin against methicillin-resistant Staphylococcus aureus

E. LaVoie, D. S. Pilch, M. Kaul, 2022, Medicinal Chemistry Research.

Synthesis of the Mixed Acetal Segment of S-Glyceroplasmalopsychosine.

D. R. Mootoo, R. Franck, Ajit K. Parhi, 2008, Tetrahedron.

Structure-activity relationships of potentiators of the antibiotic activity of clarithromycin against Escherichia coli.

E. LaVoie, D. S. Pilch, M. Kaul, 2019, European journal of medicinal chemistry.

Advances in the structural studies of antibiotic potentiators against Escherichia coli.

E. LaVoie, D. S. Pilch, M. Kaul, 2019, Bioorganic & medicinal chemistry.

Evaluation of Heterocyclic Carboxamides as Potential Efflux Pump Inhibitors in Pseudomonas aeruginosa

P. Datta, Yanlu Cao, Yongzhen Zhang, 2021, Antibiotics.

A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization.

S. Tuske, E. Arnold, E. LaVoie, 2012, Journal of medicinal chemistry.

Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors.

Steven F. Baker, E. Arnold, E. LaVoie, 2013, ACS chemical biology.

Synthesis of Fluorescent Probes based on Stilbenes and Diphenylacetylenes targeting β-Amyloid Plaques.

H. Kung, M. Kung, Ajit K. Parhi, 2008, Tetrahedron letters.

Combining the FtsZ-Targeting Prodrug TXA709 and the Cephalosporin Cefdinir Confers Synergy and Reduces the Frequency of Resistance in Methicillin-Resistant Staphylococcus aureus

E. LaVoie, D. S. Pilch, M. Kaul, 2016, Antimicrobial Agents and Chemotherapy.

Enterococcal and streptococcal resistance to PC190723 and related compounds: molecular insights from a FtsZ mutational analysis.

S. Tuske, E. Arnold, E. LaVoie, 2013, Biochimie.

Evaluation of 2,6-difluoro-3-(oxazol-2-ylmethoxy)benzamide chemotypes as Gram-negative FtsZ inhibitors

P. Datta, Yanlu Cao, Yongzhen Zhang, 2022, The Journal of Antibiotics.

TXH11106: A Third-Generation MreB Inhibitor with Enhanced Activity against a Broad Range of Gram-Negative Bacterial Pathogens

J. Y. Roberge, E. LaVoie, D. S. Pilch, 2022, Antibiotics.

2-(2'-((Dimethylamino)methyl)-4'-(3-[(18)F]fluoropropoxy)-phenylthio)benzenamine for positron emission tomography imaging of serotonin transporters.

H. Kung, M. Kung, B. Lieberman, 2008, Nuclear medicine and biology.

β-Lactam Antibiotics with a High Affinity for PBP2 Act Synergistically with the FtsZ-Targeting Agent TXA707 against Methicillin-Resistant Staphylococcus aureus

E. LaVoie, D. S. Pilch, M. Kaul, 2017, Antimicrobial Agents and Chemotherapy.

In Vivo Characterization of a Series of 18F-Diaryl Sulfides (18F-2-(2′-((Dimethylamino)Methyl)-4′-(Fluoroalkoxy)Phenylthio)Benzenamine) for PET Imaging of the Serotonin Transporter

H. Kung, B. Lieberman, Ajit K. Parhi, 2009, Journal of Nuclear Medicine.