Yanwu Yang

发表

“Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution

Brian J. Smith, F. Ismail-Beigi, P. Arvan, 2020, The Journal of Biological Chemistry.

Human Sex Determination at the Edge of Ambiguity

M. Weiss, N. Phillips, Yen-Shan Chen, 2016, The Journal of Biological Chemistry.

Structural Basis of Focal Adhesion Localization of LIM-only Adaptor PINCH by Integrin-linked Kinase*

N. Tjandra, Yun-Xing Wang, J. Qin, 2009, Journal of Biological Chemistry.

Tenuous transcriptional threshold of human sex determination. II. SRY exploits water-mediated clamp at the edge of ambiguity

E. Haas, M. Georgiadis, M. Weiss, 2022, Frontiers in Endocrinology.

Protective hinge in insulin opens to enable its receptor engagement

Brian J. Smith, Virander S. Chauhan, J. Menting, 2014, Proceedings of the National Academy of Sciences.

Genetic, Genomic and Biophysical Case Study: Familial 46, XY Sex Reversal due to a Novel Inherited Mutation in Human Testis-Determining Factor SRY

M. Weiss, A. Belgorosky, Deepak Chatterjee, 2021, bioRxiv.

Disease-causing Mutations in the Cellular Retinaldehyde Binding Protein Tighten and Abolish Ligand Interactions* 210

J. Qin, G. Holmgren, O. Sandgren, 2003, The Journal of Biological Chemistry.

Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding

Brian J. Smith, F. Ismail-Beigi, M. Lawrence, 2017, The Journal of Biological Chemistry.

Doublesex and the Regulation of Sexual Dimorphism in Drosophila melanogaster

M. Weiss, Wei Zhang, Yanwu Yang, 2008, Journal of Biological Chemistry.

Structure of the double‐stranded RNA‐binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA‐mediated activation

B. Williams, S. Nanduri, B. Carpick, 1998, The EMBO journal.

An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein

F. Ismail-Beigi, M. Lawrence, M. Weiss, 2017, The Journal of Biological Chemistry.

An Achilles' Heel in an Amyloidogenic Protein and Its Repair

R. Tycko, F. Ismail-Beigi, M. Weiss, 2010, The Journal of Biological Chemistry.

Human Sex Determination at the Edge of Ambiguity

M. Weiss, N. Phillips, Yen-Shan Chen, 2016, The Journal of Biological Chemistry.

Peptide Model of the Mutant Proinsulin Syndrome. II. Nascent Structure and Biological Implications

R. DiMarchi, M. Weiss, Michael D. Glidden, 2022, Frontiers in Endocrinology.

Peptide Model of the Mutant Proinsulin Syndrome. I. Design and Clinical Correlation

F. Ismail-Beigi, R. DiMarchi, M. Weiss, 2022, Frontiers in Endocrinology.

Evolution of insulin at the edge of foldability and its medical implications

F. Ismail-Beigi, P. Arvan, M. Weiss, 2020, Proceedings of the National Academy of Sciences.

Insertion of a Synthetic Switch Into Insulin Provides Metabolite-Dependent Regulation of Hormone-Receptor Activation

M. Lawrence, Yule Liu, T. Hattier, 2021, Proceedings of the National Academy of Sciences.

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

J. Qin, A. Vėlyvis, Y. Tu, 2002, Journal of Cell Science.

Biophysical Optimization of a Therapeutic Protein by Nonstandard Mutagenesis

F. Ismail-Beigi, M. Weiss, N. Phillips, 2014, The Journal of Biological Chemistry.

Mechanism of magnesium activation of calcium-activated potassium channels

J. Qin, Lei Hu, Jingyi Shi, 2002, Nature.

Structural and functional insights into PINCH LIM4 domain–mediated integrin signaling

J. Qin, A. Vėlyvis, O. Vinogradova, 2003, Nature Structural Biology.

Age of diabetes onset in the mutant proinsulin syndrome correlates with mutational impairment of protein foldability and stability

F. Ismail-Beigi, P. Arvan, M. Weiss, 2021, bioRxiv.

Solution Structure of the Focal Adhesion Adaptor PINCH LIM1 Domain and Characterization of Its Interaction with the Integrin-linked Kinase Ankyrin Repeat Domain*

A. Vėlyvis, J Qin, A Velyvis, 2001, The Journal of Biological Chemistry.

1H, 13C, 15N Resonance Assignment of the 20 kDa Double Stranded RNA Binding Domain of PKR

S. Nanduri, B. Carpick, B. Williams, 1998, Journal of biomolecular NMR.

Deciphering the Hidden Informational Content of Protein Sequences

P. Arvan, M. Weiss, Ming Liu, 2010, The Journal of Biological Chemistry.

Solution Structure of Proinsulin

M. Weiss, Q. Hua, Yanwu Yang, 2010, The Journal of Biological Chemistry.

Se-Glargine II. Native Function of a Basal Insulin Analog Stabilized by an Internal Diselenide Bridge

M. Weiss, Yen-Shan Chen, Balamurugan Dhayalan, 2023, bioRxiv.

Mapping the Ligand Binding Pocket in the Cellular Retinaldehyde Binding Protein* 210

J. Qin, S. Bhattacharya, N. Noy, 2003, The Journal of Biological Chemistry.

Doublesex and the Regulation of Sexual Dimorphism in Drosophila melanogaster

M. Weiss, Wei Zhang, Yanwu Yang, 2008, Journal of Biological Chemistry.

An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein

F. Ismail-Beigi, M. Lawrence, M. Weiss, 2017, The Journal of Biological Chemistry.

A corollary discharge maintains auditory sensitivity during sound production

Lei Hu, G. Krishnamoorthy, Yanwu Yang, 2022 .