A. Kolbanovskiy

发表

The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion

S. Broyde, J. Min, N. Geacintov, 2020, bioRxiv.

The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion

S. Broyde, J. Min, N. Geacintov, 2020, bioRxiv.

Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair.

N. Geacintov, O. Lavrik, N. Rechkunova, 2012, DNA repair.

Nuclear Magnetic Resonance Studies of an N2-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations

S. Broyde, S. Amin, N. Geacintov, 2014, Biochemistry.

Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes.

S. Amin, N. Geacintov, Q. Ruan, 2002, Chemical research in toxicology.

Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context

D. Patel, S. Broyde, S. Amin, 2007, Nucleic acids research.

Determination of absolute configurations of 4-hydroxyequilenin-cytosine and -adenine adducts by optical rotatory dispersion, electronic circular dichroism, density functional theory calculations, and mass spectrometry.

S. Broyde, J. Bolton, R. V. van Breemen, 2008, Chemical research in toxicology.

The stereochemistry of benzo[a]pyrene‐2′‐deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases

D. Maltseva, S. Klimašauskas, N. Geacintov, 2007, The FEBS journal.

Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not.

S. Broyde, S. Amin, N. Geacintov, 2013, Chemical research in toxicology.

Probing murine methyltransfease Dnmt3a interactions with benzo[a]pyrene‐modified DNA by fluorescence methods

N. Geacintov, A. Kolbanovskiy, N. Cherepanova, 2012, The FEBS journal.

Oxidative generation of guanine radicals by carbonate radicals and their reactions with nitrogen dioxide to form site specific 5-guanidino-4-nitroimidazole lesions in oligodeoxynucleotides.

N. Geacintov, V. Shafirovich, B. Yun, 2003, Chemical research in toxicology.

The decomposition of peroxynitrite to nitroxyl anion (NO-) and singlet oxygen in aqueous solution.

N. Geacintov, K. Frenkel, A. U. Khan, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Mirror image stereoisomers of the major benzo[a]pyrene N2-dG adduct are bypassed by different lesion-bypass DNA polymerases in E. coli.

Jun Yin, A. Nagalingam, E. Loechler, 2006, DNA repair.

Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra.

S. Broyde, L. Jia, N. Geacintov, 2009, Chemical research in toxicology.

Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods.

S. Broyde, L. Jia, N. Geacintov, 2006, Chemical research in toxicology.

Mechanism of error-free and semi-targeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4

L. Malinina, D. Patel, S. Broyde, 2010, Nature Structural &Molecular Biology.

Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene.

S. Amin, N. Geacintov, Marina Kolbanovskiy, 2011, Chemical research in toxicology.

Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin.

J. Bolton, N. Geacintov, A. Shastry, 2005, Chemical research in toxicology.

Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies

S. Broyde, Marina Kolbanovskiy, K. Kropachev, 2012, Nucleic acids research.

Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro.

S. Broyde, B. Van Houten, J. Bolton, 2011, DNA repair.

Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion–base stacking interactions

D. Patel, S. Broyde, S. Amin, 2011, Nucleic acids research.

NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms.

D. Patel, S. Broyde, J. Bolton, 2009, Biochemistry.

Absolute configurations of DNA lesions determined by comparisons of experimental ECD and ORD spectra with DFT calculations.

S. Broyde, N. Geacintov, V. Shafirovich, 2009, Chirality.

Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.

D. Patel, B. Hingerty, S. Broyde, 1994, Biochemistry.

Recognition and Removal of Bulky DNA Lesions by the Nucleotide Excision Repair System

D. Patel, S. Broyde, N. Geacintov, 2010 .

Impact of benzo[a]pyrene-2'-deoxyguanosine lesions on methylation of DNA by SssI and HhaI DNA methyltransferases.

D. Maltseva, N. Geacintov, F. Johnson, 2006, Biochemistry.

Photoinduced electron transfer and strand cleavage in pyrenyl–DNA complexes and adducts

K. Solntsev, N. Geacintov, V. Shafirovich, 1998 .

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

A. Grollman, N. Geacintov, S. Shibutani, 2002, Biochemistry.

Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide.

N. Geacintov, V. Shafirovich, A. Kolbanovskiy, 2002, Chemical research in toxicology.

Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.

Yanbin Zhang, Xiaohua Wu, Zhigang Wang, 2003, Biochemistry.

Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase

A. Aggarwal, N. Geacintov, O. Rechkoblit, 2017, Nature Communications.

Human DNA polymerases catalyze lesion bypass across benzo[a]pyrene-derived DNA adduct clustered with an abasic site.

N. Geacintov, O. Lavrik, N. Rechkunova, 2014, DNA repair.

The human DNA repair factor XPC‐HR23B distinguishes stereoisomeric benzo[a]pyrenyl‐DNA lesions

S. Broyde, J. Egly, N. Geacintov, 2007, The EMBO journal.

Effects of benzo[a]pyrene-deoxyguanosine lesions on DNA methylation catalyzed by EcoRII DNA methyltransferase and on DNA cleavage effected by EcoRII restriction endonuclease.

S. Eremin, F. Subach, N. Geacintov, 2005, Biochemistry.

Dnmt3a-CD is less susceptible to bulky benzo[a]pyrene diol epoxide-derived DNA lesions than prokaryotic DNA methyltransferases.

A. Baykov, A. Kolbanovskiy, E. Gromova, 2011, Biochemistry.

Novel Enzymatic Function of DNA Polymerase ν in Translesion DNA Synthesis Past Major Groove DNA−Peptide and DNA−DNA Cross-Links

R. Wood, K. Takata, I. Minko, 2010, Chemical research in toxicology.

Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove.

D. Patel, B. Hingerty, S. Broyde, 2000, Journal of molecular biology.

Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins.

B. Van Houten, S. Amin, Y. Zou, 2007, Biochemistry.

Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase

A. Aggarwal, N. Geacintov, O. Rechkoblit, 2017, Nature Communications.