P. Gao

发表

Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA

M. Ascano, T. Tuschl, D. Patel, 2014, Cell reports.

Creatine promotes cancer metastasis through activation of Smad2/3.

D. Hsu, Pengcheng Bu, Fei Zhang, 2021, Cell metabolism.

Crystal structure of a putative methylmalonyl‐coenzyme a epimerase from Thermoanaerobacter tengcongensis at 2.0 Å resolution

D. Liang, Liang Shi, P. Gao, 2009, Proteins.

Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2

Jincun Zhao, yang-xin fu, Haidong Tang, 2021, Cell Research.

Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein.

Yina Gao, G. Gao, Xinlu Wang, 2020, Cell reports.

Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors

G. Gao, Yong Wang, Xinlu Wang, 2020, Nature Communications.

Viral tegument proteins restrict cGAS-DNA phase separation to mediate immune evasion.

H. Deng, Yina Gao, Yun Feng, 2021, Molecular cell.

Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems

Yina Gao, Yong Wang, P. Gao, 2022, Nature Communications.

The selectivity of Mannich-reaction-based modification on amino acid residues in silk fibroin

Jinhuan Zheng, P. Gao, Wei‐guo Chen, 2022, Dyes and Pigments.

The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS

P. Gao, Dandan Lin, Zhi-Dong Zhang, 2022, Nature Communications.

Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments

H. Deng, P. Xu, P. Gao, 2022, The Journal of cell biology.

V-cGAPs: attenuators of 3′3′-cGAMP signaling

D. Patel, P. Gao, 2015, Cell Research.

Binding-Pocket and Lid-Regi on Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA Graphical

M. Ascano, T. Tuschl, D. Patel, 2014 .

Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage

Pu Gao, R. Micura, D. Patel, 2016, Nature chemical biology.

DNA sensor cGAS-mediated immune recognition

G. Gao, Shuo Wang, P. Xia, 2016, Protein & Cell.

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

Roger A. Jones, M. Ascano, T. Tuschl, 2013, Cell.

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Roger A. Jones, M. Ascano, T. Tuschl, 2013, Cell.

Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed -1 Ribosomal Frameshifting

S. Goff, Fuquan Yang, Xiang Ding, 2019, Cell.

Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome

Hao Wu, R. Negro, R. Flavell, 2021, Cell.

PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease

D. Patel, K. Rajashankar, Hui Yang, 2016, Cell.

Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition

D. Patel, K. Rajashankar, Hui Yang, 2016, Cell Research.

Structural basis underlying complex assembly and conformational transition of the type I R-M system

P. Gao, Xiao-Xue Yan, L. Tian, 2017, Proceedings of the National Academy of Sciences.

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

T. Tuschl, D. Patel, A. Stamford, 2019, Nature Communications.

Molecular basis of RADAR anti-phage supramolecular assemblies

Yina Gao, F. Ye, P. Gao, 2023, Cell.

Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.

A. Serganov, G. Gao, Ang Gao, 2019, Molecular cell.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

T. Tuschl, D. Patel, A. Stamford, 2019, Nature Communications.

Structure of HsdS Subunit from Thermoanaerobacter tengcongensis Sheds Lights on Mechanism of Dynamic Opening and Closing of Type I Methyltransferase

Xiaoxue Yan, X. An, D. Liang, 2011, PloS one.

Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors

G. Gao, Yong Wang, Xinlu Wang, 2020, Nature Communications.

Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE

Ang Gao, Yong Wang, P. Gao, 2018, Cell.

SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action

P. Greengard, B. Chait, D. Patel, 2013, Cell.

Structural insights into assembly, operation and inhibition of a type I restriction–modification system

Yina Gao, Xinzheng Zhang, P. Gao, 2020, Nature Microbiology.

RecOR complex including RecR N-N dimer and RecO monomer displays a high affinity for ssDNA

X. An, D. Liang, A. Gao, 2012, Nucleic acids research.

Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10

H. Deng, Yang Yu, Yong Wang, 2020, Proceedings of the National Academy of Sciences.

Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes

Yong Wang, P. Gao, Han Feng, 2017, Protein & Cell.

GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3

S. Singh, H. Cai, J. Lou, 2023, The Journal of cell biology.

Recognition of cyclic dinucleotides and folates by human SLC19A1

Jun Ma, Yina Gao, J. Lou, 2022, Nature.

Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

Lactate modulates iron metabolism by binding soluble adenylyl cyclase.

T. Ganz, Shuping Zhang, Wei Liu, 2023, Cell metabolism.

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

The GxcM-Fbp17/RacC-WASP signaling cascade regulates polarized cortex assembly in migrating cells

S. Singh, H. Cai, J. Lou, 2022, bioRxiv.

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Roger A. Jones, M. Ascano, T. Tuschl, 2013, Cell.

Crystal structure of a putative methylmalonyl‐coenzyme a epimerase from Thermoanaerobacter tengcongensis at 2.0 Å resolution

D. Liang, Liang Shi, P. Gao, 2009, Proteins.