M. Lakshman

发表

A Rapid, High-Yield Method for 5′-Hydroxyl Protection in Very Reactive and Amino Group Modified Nucleosides Using Dimethoxytrityl Tetrafluoroborate

M. Lakshman, B. Zajc, 1996 .

The Disappearing Director: The Case of Directed N-Arylation via a Removable Hydroxyl Group.

Michelle C. Neary, P. Pradhan, M. Lakshman, 2018, Advanced synthesis & catalysis.

Mild and General Access to Diverse 1H-Benzotriazoles via Diboron-Mediated N-OH Deoxygenation and Palladium-Catalyzed C-C and C-N Bond Formation.

M. Lakshman, Narender Pottabathini, V. Gurram, 2015, Advanced synthesis & catalysis.

Direct arylation of 6-phenylpurine and 6-arylpurine nucleosides by ruthenium-catalyzed C-H bond activation.

R. Pratap, P. Pradhan, Raghu Ram Chamala, 2011, Angewandte Chemie.

Facile Pd-catalyzed cross-coupling of 2'-deoxyguanosine O6-arylsulfonates with arylboronic acids.

M. Lakshman, Bill Boggess, Paul F. Thomson, 2002, Organic letters.

Synthesis of deuterated 1,2,3-triazoles.

M. Lakshman, H. Akula, 2012, The Journal of organic chemistry.

Synthesis and biological properties of C-2 triazolylinosine derivatives.

J. Balzarini, B. Day, G. Andrei, 2012, The Journal of organic chemistry.

Structure/reactivity relationships in the benzo[c]phenanthrene skeleton: stable ion and electrophilic substitution (nitration, bromination) study of substituted analogues, novel carbocations and substituted derivatives.

K. Laali, C. Brulé, T. Okazaki, 2007, The Journal of organic chemistry.

Influence of biaryl phosphine structure on C-N and C-C bond formation.

D. Venkataraman, R. Pratap, Padma Gunda, 2009, Journal of the American Chemical Society.

Pd-catalyzed amination of nucleoside arylsulfonates to yield N6-aryl-2,6-diaminopurine nucleosides.

L. Russon, Padma Gunda, M. Lakshman, 2004, Angewandte Chemie.

Cross-dehydrogenative coupling and oxidative-amination reactions of ethers and alcohols with aromatics and heteroaromatics

M. Lakshman, Prasanna K. Vuram, 2017, Chemical science.

A novel bis(pinacolato)diboron-mediated N-O bond deoxygenative route to C6 benzotriazolyl purine nucleoside derivatives.

P. Pradhan, M. Lakshman, Lijia Yang, 2016, Organic & biomolecular chemistry.

Palladium-catalyzed C–N and C–C cross-couplings as versatile, new avenues for modifications of purine 2′-deoxynucleosides

M. Lakshman, 2002 .

Cycloaddition of Arynes and Cyclic Enol Ethers as a Platform for Access to Stereochemically Defined 1,2-Disubstituted Benzocyclobutenes.

P. Pradhan, M. Lakshman, Lijia Yang, 2015, European journal of organic chemistry.

Purinyl N1-directed aromatic C-H oxidation in 6-arylpurines and 6-arylpurine nucleosides.

P. Pradhan, Raghu Ram Chamala, M. Lakshman, 2013, The Journal of organic chemistry.

General Approach to N6,C5'-Difunctionalization of Adenosine.

P. Pradhan, M. Lakshman, Lijia Yang, 2021, The Journal of organic chemistry.

Reduction of amine N-oxides by diboron reagents.

H. Kokatla, M. Lakshman, Venkata Ramana Doddi, 2011, The Journal of organic chemistry.

Simple Synthesis of Amides and Weinreb Amides via Use of PPh3 or Polymer-Supported PPh3 and Iodine.

Amit Kumar, M. Lakshman, H. Akula, 2010, European journal of organic chemistry.

Diarylmethanes through an Unprecedented Palladium‐Catalyzed C−C Cross‐Coupling of 1‐(Aryl)methoxy‐1 H‐Benzotriazoles with Arylboronic Acids

M. Lakshman, Manish K. Singh, 2015, ChemCatChem.

A simple synthesis of nitriles from aldoximes.

M. Singh, M. Lakshman, 2009, The Journal of organic chemistry.

Stable ion study of benzo[a]pyrene (BaP) derivatives: 7,8-dihydro-BaP, 9,10-dihydro-BaP and its 6-halo derivatives, 1- and 3-methoxy-9,10-dihydro-BaP-7(8H)-one, as well as the proximate carcinogen BaP 7,8-dihydrodiol and its dibenzoate, combined with a comparative DNA binding study of regioisomeric

Subodh Kumar, W. Baird, K. Laali, 2003, Organic & biomolecular chemistry.

Base Modifications of Nucleosides via the Use of Peptide‐Coupling Agents, and Beyond

M. Lakshman, 2022, Chemical record.

Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine.

Wei Wei, M. Lakshman, B. Zajc, 2019, Advanced synthesis & catalysis.

Unusual deoxygenation and reactivity studies related to O6-(benzotriazol-1-yl)inosine derivatives.

M. Lakshman, Suyeal Bae, 2008, The Journal of organic chemistry.

A simple method for C-6 modification of guanine nucleosides.

M. Lakshman, J. Frank, 2009, Organic and biomolecular chemistry.

Synthesis of N6,N6‐Dialkyladenine Nucleosides Using Hexaalkylphosphorus Triamides Produced in Situ

Amit Kumar, P. Pradhan, M. Lakshman, 2008 .

Palladium-Catalyzed C−N Bond Formation: Facile and General Synthesis of N6-Aryl 2‘-Deoxyadenosine Analogues

J. Keeler, M. Lakshman, J. Hilmer, 1999 .

A general synthesis of C6-azolyl purine nucleosides.

L. Russon, M. Lakshman, P. Lagisetty, 2006, Angewandte Chemie.

Azide-tetrazole equilibrium of C-6 azidopurine nucleosides and their ligation reactions with alkynes.

B. Day, M. Singh, R. Balachandran, 2010, The Journal of organic chemistry.

Synthetic, crystallographic, computational, and biological studies of 1,4-difluorobenzo[c]phenanthrene and its metabolites.

H. L. Carrell, J. Glusker, A. K. Katz, 2007, The Journal of organic chemistry.

Synthesis of Biologically Important Nucleoside Analogs by Palladium- Catalyzed C-N Bond-Formation

M. Lakshman, 2005 .

1,1,3,6‐Tetrabromonaphthalen‐2(1H)‐one

M. Singh, M. Lakshman, 2010 .

ACYL MIGRATION IN ANIONS DERIVED FROM NONENOLIZABLE ESTERS OF POLYCYCLIC AROMATIC HYDROCARBONS

M. Lakshman, B. Zajc, 1995 .

Regioselective ring opening of polycyclic aromatic hydrocarbon epoxides by polymer-supported azide anion

M. Lakshman, D. Nadkarni, R. Lehr, 1990 .

Modular, Metal-Catalyzed Cycloisomerization Approach to Angularly Fused Polycyclic Aromatic Hydrocarbons and Their Oxidized Derivatives.

P. Pradhan, M. Lakshman, Paul F. Thomson, 2015, The Journal of organic chemistry.

Cladribine Analogues via O⁶-(Benzotriazolyl) Derivatives of Guanine Nucleosides.

R. Kreitman, M. Lakshman, Lijia Yang, 2015, Molecules.

Epoxide and diol epoxide adducts of polycyclic aromatic hydrocarbons at the exocyclic amino group of deoxyguanosine

D. Jerina, J. M. Sayer, M. Lakshman, 1992 .

C-C cross-coupling reactions of O6-alkyl-2-haloinosine derivatives and a one-pot cross-coupling/O6-deprotection procedure.

B. Patro, M. Lakshman, Narender Pottabathini, 2012, Chemistry, an Asian journal.

Regio and stereocontrolled synthesis of aryl cis aminoalcohols from cis glycols

M. Lakshman, B. Zajc, 1996 .

Palladium-catalyzed synthesis of carcinogenic polycyclic aromatic hydrocarbon epoxide-nucleoside adducts: the first amination of a chloro nucleoside.

Padma Gunda, M. Lakshman, 2003, Organic letters.

Pd-Xantphos-catalyzed direct arylation of nucleosides.

M. Lakshman, F. Ngassa, Kyle A Dekorver, 2006, Organic letters.

Cladribine Analogues via O6-(Benzotriazolyl) Derivatives of Guanine Nucleosides

R. Kreitman, M. Lakshman, Lijia Yang, 2015, Molecules.

A novel polymer supported approach to nucleoside modification.

M. Lakshman, Suyeal Bae, 2008, The Journal of organic chemistry.

O6-(benzotriazol-1-yl)inosine derivatives: easily synthesized, reactive nucleosides.

M. Lakshman, Suyeal Bae, 2007, Journal of the American Chemical Society.

Site-specific modification of the human N-ras proto-oncogene with each diol epoxide metabolite of benzo[a]pyrene and thermal denaturation studies of the adducted duplexes.

M. Lakshman, S. Chaturvedi, 1996, Carcinogenesis.

Synthesis of polycyclic aromatic hydrocarbon 2′-deoxyadenosine analogs

M. Lakshman, R. Lehr, 1990 .

Cladribine Analogues via O 6 -(Benzotriazolyl) Derivatives of

R. Kreitman, M. Lakshman, Lijia Yang, 2015 .

Facile synthesis of 1-alkoxy-1H-benzo- and 7-azabenzotriazoles from peptide coupling agents, mechanistic studies, and synthetic applications

M. Singh, Mukesh Kumar, Raghu Ram Chamala, 2014, Beilstein journal of organic chemistry.

Synthesis and Evaluations of “1,4‐Triazolyl Combretacoumarins” and Desmethoxy Analogs

D. Schols, G. Andrei, R. Snoeck, 2019, European journal of organic chemistry.

Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H‐Benzotriazol‐1‐yloxy‐tris(dimethyl‐amino)phosphonium Hexafluorophosphate

M. Lakshman, H. Akula, 2019, Current protocols in nucleic acid chemistry.

Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products.

J. Balzarini, D. Schols, G. Andrei, 2017, Organic & biomolecular chemistry.

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

H. Kokatla, M. Lakshman, 2012, Current protocols in nucleic acid chemistry.

Synthetic utility of an isolable nucleoside phosphonium salt.

M. Lakshman, Suyeal Bae, 2008, Organic letters.

Mild and room temperature C-C bond forming reactions of nucleoside C-6 arylsulfonates.

Padma Gunda, P. Pradhan, M. Lakshman, 2005, The Journal of organic chemistry.

Palladium‐Catalyzed Aryl Amination Reactions of 6‐Bromo‐ and 6‐Chloropurine Nucleosides

J. Balzarini, Erik de Clercq, M. Lakshman, 2010, Advanced synthesis & catalysis.

O6‐(Benzotriazol‐1‐yl)inosine Derivatives for C6 Modification of Purine Nucleosides

M. Lakshman, Suyeal Bae, S. Chaturvedi, 2009, Current protocols in nucleic acid chemistry.

Palladium‐Catalyzed C—N Bond Formation: Facile and General Synthesis of N6‐Aryl 2′‐Deoxyadenosine Analogues.

J. Keeler, M. Lakshman, J. Hilmer, 1999 .

Gross pathology in female wistar rats due to hexavalent chromium toxicity

A. Reddy, M. Lakshman, Anand Kumar, 2020 .

Cutaneous mycotic granuloma (dermatomycosis) in fowl: a pathomorphological observations.

M. Lakshman, C. Balachandran, Y. Nagamalleswari, 2009 .

Qualitative and quantitative changes of fried fish steaks and fish steak curry of catla (Catla catla) during frozen storage.

A. D. Reddy, S. K. Udgata, M. Lakshman, 2015 .

Highly diastereoselective synthesis of nucleoside adducts from the carcinogenic benzo[a]pyrene diol epoxide and a computational analysis.

P. Pradhan, J. Keeler, M. Lakshman, 2007, Journal of the American Chemical Society.

Palladium catalysis for the synthesis of hydrophobic C-6 and C-2 aryl 2'-deoxynucleosides. Comparison of C-C versus C-N bond formation as well as C-6 versus C-2 reactivity.

L. Russon, J. Keeler, M. Lakshman, 2001, Journal of the American Chemical Society.

Effects of Polycyclic Aromatic Hydrocarbon Adducts with Deoxyguanosine and Deoxyadenosine in vivo and in vitro

D. Jerina, A. Dipple, R. Agarwal, 1996 .

Primer extension by various polymerases using oligonucleotide templates containing stereoisomeric benzo[a]pyrene-deoxyadenosine adducts.

D. Jerina, A. Dipple, J. M. Sayer, 1994, Biochemistry.

Solvent Dependent Changes in the Proton NMR Spectra of 2′-Deoxyadenosine and Its Derivatives

M. Lakshman, R. Lehr, 1992 .

Chemical synthesis of a bay-region polycyclic aromatic hydrocarbon tetrahydroepoxide-deoxyadenosine adduct and its site-specific incorporation into a DNA oligomer

D. Jerina, J. M. Sayer, M. Lakshman, 1991 .

Sequence context profoundly influences the mutagenic potency of trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-purine nucleoside adducts in site-specific mutation studies.

D. Jerina, A. Dipple, J. M. Sayer, 1998, Biochemistry.

Synthesis of 1,2-Epoxy-1,2,3,4-Tetrahydrobenzo[g]chrysene: The First Synthesis of a FJORD-Region Tetrahydroepoxide

M. Lakshman, R. Lehr, 1994 .

Synthesis of deoxyadenosine adducts from the highly carcinogenic fjord region diol epoxide of benzo[c]phenanthrene

D. Jerina, H. Yeh, H. Yagi, 1992 .

Synthesis and duplex-forming properties of a nonanucleotide containing an N6-deoxyadenosine adduct of a bay-region diol epoxide

D. Jerina, J. M. Sayer, H. Yagi, 1992 .

Simple Methodology for Heck Arylation at C‐8 of Adenine Nucleosides

Li Zhang, M. Lakshman, P. Lagisetty, 2008 .

Palladium Catalysis for the Synthesis of Hydrophobic C-6 and C-2 Aryl 2′-Deoxynucleosides. Comparison of C-C versus C-N Bond Formation as well as C-6 versus C-2 Reactivity.

L. Russon, J. Keeler, M. Lakshman, 2001 .

Palladium-catalyzed synthesis of nucleoside adducts from bay- and fjord-region diol epoxides.

P. Pradhan, M. Lakshman, Elise Champeil, 2007, The Journal of organic chemistry.

Ruthenium-Catalyzed C-H Bond Activation Approach to Azolyl Aminals and Hemiaminal Ethers, Mechanistic Evaluations, and Isomer Interconversion.

M. Singh, M. Lakshman, L. Stahl, 2016, ACS catalysis.

NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10R adduct derived from trans addition of a deoxyadenosine N6-amino group to (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene.

D. Gorenstein, D. Jerina, H. Yeh, 1995, Biochemistry.

NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10S adduct derived from trans addition of a deoxyadenosine N6-amino group to (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene: an unusual syn glycosidic torsion angle at the modified dA.

D. Gorenstein, D. Jerina, A. Altieri, 1995, Biochemistry.

Synthesis and site-specific incorporation of a bay-region cis ring-opened tetrahydro epoxide-deoxyadenosine adduct into a DNA oligomer

D. Jerina, J. M. Sayer, M. Lakshman, 1992 .

Facile Synthesis of O6‐Alkyl‐, O6‐Aryl‐, and Diaminopurine Nucleosides from 2′‐Deoxyguanosine.

L. Russon, J. Keeler, M. Lakshman, 2000 .

Testicular Toxicity Induced by Glyphosate (GLP) and Ameliorative Effect of Vitamin C in Wistar Rats

M. Lakshman, Anil Kumar, M. Jeevanalatha, 2020 .

Haematobiochemical changes in Jatropha deoiled seed cake (Jatropha curcas) induced toxicity in broiler chicken and their amelioration.

B. Padmaja, P. Sirisha, M. Lakshman, 2008 .

Methyl Group-Induced Helicity in 1,4-Dimethylbenzo[c]phenanthrene and Its Metabolites: Synthesis, Physical, and Biological Properties

H. L. Carrell, J. Glusker, C. Afshar, 2000 .

KHF2: A Mild and Selective Desilylating Agent for Phenol tert-Butyldimethylsilyl (TBDMS) Ethers

M. Lakshman, B. Zajc, Michael S A Benavidez, 2016, Synlett.

Synthesis and Assignment of Absolute Configuration to the N6-Deoxyadenosine Adducts Resulting from Cis and Trans Ring-Opening of Phenanthrene 9,10-Oxide

D. Jerina, J. M. Sayer, W. Xiao, 1994 .

Pd‐Catalyzed versus Uncatalyzed, PhI(OAc)2‐Mediated Cyclization Reactions of N6‐([1,1′‐Biaryl]‐2‐yl)Adenine Nucleosides

P. Pradhan, M. Lakshman, Lijia Yang, 2017, ChemCatChem.

Benzimidazopurine nucleosides from N6-aryl adenosine derivatives by PhI(OAc)2-mediated C-N bond formation, no metal needed.

M. Lakshman, Sakilam Satishkumar, 2017, Chemical communications.

A General Chemoenzymatic Synthesis of Enantiopure cis β-Amino Alcohols from Microbially Derived cis-Glycols

D. Gibson, M. Lakshman, B. Zajc, 1998 .

Multiple fluorescence lifetimes for oligonucleotides containing single, site-specific modifications at guanine and adenine corresponding to trans addition of exocyclic amino groups to (+)-(7R,8S,9S,10R)- and (+)-(7S,8R,9R,10S) -7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

D. Jerina, J. M. Sayer, H. Fernando, 1995, Chemical Research in Toxicology.

Resolution of polycyclic aromatic hydrocarbon dihydrodiols via diastereomeric formaldehyde acetals

M. B. Myers, M. Lakshman, P. Kole, 1997 .

Pd-catalyzed C-C bond-forming reactions of thymidine mesitylene sulfonate.

E. De Clercq, M. Lakshman, S. B. Kang, 2007, The Journal of organic chemistry.

C-C cross-coupling reactions of O6-alkyl-2-haloinosine derivatives and a one-pot cross-coupling/O6-deprotection procedure.

B. Patro, M. Lakshman, Narender Pottabathini, 2012, Chemistry, an Asian journal.

Improved High-Yield Synthesis of Polycyclic Aromatic Hydrocarbon Amino Tribenzoates, Nucleophilic Components for Synthesis of Diol Epoxide-Nucleoside Adducts

M. Lakshman, R. Lehr, S. Chaturvedi, 1994 .