A. S. Abu Lila

发表

Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.

M. Fukushima, H. Wada, C. Kato, 2016, International journal of oncology.

Sequential administration with oxaliplatin-containing PEG-coated cationic liposomes promotes a significant delivery of subsequent dose into murine solid tumor.

T. Ishida, H. Kiwada, Kazuya Nakamura, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Complement activation induced by PEG enhances humoral immune responses against antigens encapsulated in PEG-modified liposomes.

T. Ishida, Taro Shimizu, H. Ando, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer

Hisham A. Abbas, M. Safo, Hani Asfour, 2021, Applied Sciences.

Formulation, characterization, and cellular toxicity assessment of tamoxifen-loaded silk fibroin nanoparticles in breast cancer

H. Arab, H. Gangadharappa, A. Moin, 2021, Drug delivery.

Application of polyglycerol coating to plasmid DNA lipoplex for the evasion of the accelerated blood clearance phenomenon in nucleic acid delivery.

T. Ishida, H. Kiwada, Y. Uehara, 2014, Journal of pharmaceutical sciences.

The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage.

T. Ishida, H. Kiwada, A. S. Abu Lila, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration.

T. Ishida, H. Kiwada, Taro Shimizu, 2013, International journal of pharmaceutics.

Oxaliplatin encapsulated in PEG-coated cationic liposomes induces significant tumor growth suppression via a dual-targeting approach in a murine solid tumor model.

T. Ishida, H. Kiwada, S. Kizuki, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Abrogation of the accelerated blood clearance phenomenon by SOXL regimen: promise for clinical application.

T. Ishida, H. Kiwada, A. S. Abu Lila, 2013, International journal of pharmaceutics.

Co‐administration of liposomal l‐OHP and PEGylated TS shRNA‐lipoplex: A novel approach to enhance anti‐tumor efficacy and reduce the immunogenic response to RNAi molecules

M. Fukushima, H. Wada, T. Ishida, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model

M. Matsunaga, T. Ishida, H. Kiwada, 2012, Drug Delivery and Translational Research.

Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2016, International journal of nanomedicine.

I.p.-injected cationic liposomes are retained and accumulate in peritoneally disseminated tumors.

T. Ishida, Taro Shimizu, H. Ando, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Tumor-type-dependent vascular permeability constitutes a potential impediment to the therapeutic efficacy of liposomal oxaliplatin.

T. Ishida, H. Kiwada, A. S. Abu Lila, 2012, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Pulmonary Targeting of Levofloxacin Using Microsphere-Based Dry Powder Inhalation

D. V. Gowda, Turki Al Hagbani, A. Moin, 2022, Pharmaceuticals.

Multiple administration of PEG-coated liposomal oxaliplatin enhances its therapeutic efficacy: a possible mechanism and the potential for clinical application.

T. Ishida, H. Kiwada, Noha Essam Eldin, 2012, International journal of pharmaceutics.

Systemically Administered RNAi Molecule Sensitizes Malignant Pleural Mesotheliomal Cells to Pemetrexed Therapy.

M. Fukushima, H. Wada, T. Ishida, 2016, Molecular pharmaceutics.

Advanced therapeutic approach for the treatment of malignant pleural mesothelioma via the intrapleural administration of liposomal pemetrexed.

C. Kato, K. Kawazoe, T. Ishida, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice.

T. Ishida, Taro Shimizu, H. Ando, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Doxorubicin Expands in Vivo Secretion of Circulating Exosome in Mice.

T. Ishida, Taro Shimizu, H. Ando, 2018, Biological & pharmaceutical bulletin.

A Novel Platform for Cancer Vaccines: Antigen-Selective Delivery to Splenic Marginal Zone B Cells via Repeated Injections of PEGylated Liposomes

G. Storm, T. Ishida, Taro Shimizu, 2018, The Journal of Immunology.

The Co-Delivery of Oxaliplatin Abrogates the Immunogenic Response to PEGylated siRNA-Lipoplex

T. Ishida, H. Kiwada, Naoto Moriyoshi, 2013, Pharmaceutical Research.

Intratumoral Visualization of Oxaliplatin within a Liposomal Formulation Using X-ray Fluorescence Spectrometry.

N. Yagi, Y. Terada, T. Ishida, 2018, Molecular pharmaceutics.

Ex-vivo/in-vitro anti-polyethylene glycol (PEG) immunoglobulin M production from murine splenic B cells stimulated by PEGylated liposome.

T. Ishida, H. Kiwada, Taro Shimizu, 2013, Biological & pharmaceutical bulletin.

A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research.

T. Ishida, Taro Shimizu, H. Ando, 2018, Biological & pharmaceutical bulletin.

Elevated Levels of IL-33, IL-17 and IL-25 Indicate the Progression from Chronicity to Hepatocellular Carcinoma in Hepatitis C Virus Patients

Hisham A. Abbas, T. Ibrahim, W. Abdulaal, 2022, Pathogens.

Mebeverine Hydrochloride Loaded Chitosan Microspheres as Potential Treatment Targeting Irritable Bowel Syndrome: Box-Behnken Design Optimization

Azza A. Hasan, A. S. Abu Lila, A. Lila, 2020 .

Immunological responses to PEGylated proteins

T. Ishida, A. S. Abu Lila, Nehal E. Elsadek, 2020 .

Anti-ulcer properties, cytokines, and apoptosis regulatory effects of Olea europaea leaves from Hail Province, Saudi Arabia

Marwa H. Abdallah, Rahamat Unissa, S. Abdelwahab, 2022, Notulae Botanicae Horti Agrobotanici Cluj-Napoca.

Phytosomes as a Plausible Nano-Delivery System for Enhanced Oral Bioavailability and Improved Hepatoprotective Activity of Silymarin

A. Moin, El-Sayed Khafagy, R. G. Shriram, 2022, Pharmaceuticals.

Cytotoxic and Apoptotic Effect of Rubus chingii Leaf Extract against Non-Small Cell Lung Carcinoma A549 Cells

El-Sayed Khafagy, A. S. Abu Lila, Ahmed Al Saqr, 2022, Processes.

Design, in vitro/in vivo evaluation of meclizine HCl-loaded floating microspheres targeting pregnancy-related nausea and vomiting

Marwa H. Abdallah, A. S. Abu Lila, H. El-ghamry, 2018, Journal of Drug Delivery Science and Technology.

A simplified method for manufacturing RNAi therapeutics for local administration.

M. Fukushima, H. Wada, T. Ishida, 2019, International journal of pharmaceutics.

A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes.

T. Ishida, Taro Shimizu, H. Ando, 2022, International journal of pharmaceutics.

Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model

T. Ishida, Taro Shimizu, H. Ando, 2017, Cancer science.

Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model.

M. Fukushima, H. Wada, T. Ishida, 2017, Cancer letters.

Development and optimization of dual drug-loaded nanoparticles for the potent anticancer effect on renal carcinoma

D. V. Gowda, M. Soliman, A. Moin, 2020 .

Pegfilgrastim (PEG-G-CSF) Induces Anti-polyethylene Glycol (PEG) IgM via a T Cell-Dependent Mechanism.

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2020, Biological & pharmaceutical bulletin.

Experimental Design and Optimization of Nano-Transfersomal Gel to Enhance the Hypoglycemic Activity of Silymarin

El-Sayed Khafagy, Khaled Almansour, A. S. Abu Lila, 2022, Polymers.

Preparation, characterization and evaluation of anti-inflammatory and anti-nociceptive effects of brucine-loaded nanoemulgel.

M. Soliman, Heba S. Elsewedy, Rahamat Unissa, 2021, Colloids and surfaces. B, Biointerfaces.

Tailoring of Novel Bile Salt Stabilized Vesicles for Enhanced Transdermal Delivery of Simvastatin: A New Therapeutic Approach against Inflammation

El-Sayed Khafagy, B. Almutairy, A. S. Abu Lila, 2023, Polymers.

Development and Evaluation of Clove and Cinnamon Supercritical Fluid Extracts-Loaded Emulgel for Antifungal Activity in Denture Stomatitis

D. V. Gowda, M. Iyer, H. Arab, 2022, Gels.

Anti-diabetics and antimicrobials: Harmony of mutual interplay

Hisham A. Abbas, A. S. Abu Lila, W. Hegazy, 2021, World Journal of Diabetes.

Liposomal Delivery Systems: Design Optimization and Current Applications.

T. Ishida, A. S. Abu Lila, 2017, Biological & pharmaceutical bulletin.

Revitalizing the local anesthetic effect of Mebeverine hydrochloride via encapsulation within ethosomal vesicular system.

Azza A. Hasan, A. S. Abu Lila, R. Samir, 2020, Colloids and surfaces. B, Biointerfaces.

Nano-Conversion of Ineffective Cephalosporins into Potent One against Resistant Clinical Uro-Pathogens via Gold Nanoparticles

A. Moin, El-Sayed Khafagy, T. Hussain, 2023, Nanomaterials.

PEGylated liposomes: immunological responses

J. Szebeni, T. Ishida, Taro Shimizu, 2019, Science and technology of advanced materials.

Impact of pre-existing or induced anti-PEG IgM on the pharmacokinetics of peginterferon alfa-2a (Pegasys®) in mice.

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2020, Molecular pharmaceutics.

A double-modulation strategy in cancer treatment with a chemotherapeutic agent and siRNA.

M. Matsunaga, T. Ishida, H. Kiwada, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Ganetespib with Methotrexate Acts Synergistically to Impede NF-κB/p65 Signaling in Human Lung Cancer A549 Cells

Turki Al Hagbani, H. Gangadharappa, El-Sayed Khafagy, 2023, Pharmaceuticals.

Metronomic chemotherapy and nanocarrier platforms.

T. Ishida, A. S. Abu Lila, 2017, Cancer letters.

Secnidazole Is a Promising Imidazole Mitigator of Serratia marcescens Virulence

Hisham A. Abbas, Hani Asfour, El-Sayed Khafagy, 2021, Microorganisms.

Preparation and characterization of intravaginal vardenafil suppositories targeting a complementary treatment to boost in vitro fertilization process

Azza A. Hasan, E. Gomaa, A. S. Abu Lila, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Recent advances in tumor vasculature targeting using liposomal drug delivery systems

T. Ishida, H. Kiwada, A. S. Abu Lila, 2009, Expert opinion on drug delivery.

Modulation of Drug Release from Natural Polymer Matrices by Response Surface Methodology: in vitro and in vivo Evaluation

H. Gangadharappa, A. Moin, S. A. Ashraf, 2020, Drug design, development and therapy.

Inflammation targeted nanomedicines: patents and applications in cancer therapy.

H. Gangadharappa, A. Moin, S. Shakil, 2022, Seminars in cancer biology.

Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Pulmonary Targeting of Inhalable Moxifloxacin Microspheres for Effective Management of Tuberculosis

D. V. Gowda, A. Moin, El-Sayed Khafagy, 2021, Pharmaceutics.

Sequential treatment of oxaliplatin-containing PEGylated liposome together with S-1 improves intratumor distribution of subsequent doses of oxaliplatin-containing PEGylated liposome.

T. Ishida, H. Kiwada, A. S. Abu Lila, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Targeting Anticancer Drugs to Tumor Vasculature Using Cationic Liposomes

T. Ishida, H. Kiwada, A. S. Abu Lila, 2010, Pharmaceutical Research.

Preparation and Characterization of a Novel Mucoadhesive Carvedilol Nanosponge: A Promising Platform for Buccal Anti-Hypertensive Delivery

S. Alshahrani, A. Alshetaili, Mohammed F. Aldawsari, 2022, Gels.

Vardenafil-Loaded Bilosomal Mucoadhesive Sponge for Buccal Delivery: Optimization, Characterization, and In Vivo Evaluation

Mohammed F. Aldawsari, El-Sayed Khafagy, A. S. Abu Lila, 2022, Polymers.

Delafloxacin-Capped Gold Nanoparticles (DFX-AuNPs): An Effective Antibacterial Nano-Formulation of Fluoroquinolone Antibiotic

Turki Al Hagbani, A. Moin, T. Hussain, 2022, Materials.

Relationship between the concentration of anti-polyethylene glycol (PEG) immunoglobulin M (IgM) and the intensity of the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes in mice.

T. Ishida, H. Kiwada, Taro Shimizu, 2015, Biological & pharmaceutical bulletin.

Encapsulation in a rapid-release liposomal formulation enhances the anti-tumor efficacy of pemetrexed in a murine solid mesothelioma-xenograft model.

K. Kawazoe, T. Ishida, Noha Essam Eldin, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection

K. Tajima, T. Ishida, Taro Shimizu, 2021, Nanomaterials.

Ganglioside inserted into PEGylated liposome attenuates anti‐PEG immunity

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Tamoxifen-loaded functionalized graphene nanoribbons for breast cancer therapy

M. Soliman, H. Gangadharappa, Tamer M. Shehata, 2021 .

A hydroxyl PEG version of PEGylated liposomes and its impact on anti‐PEG IgM induction and on the accelerated clearance of PEGylated liposomes

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Screening of Apoptosis Pathway-Mediated Anti-Proliferative Activity of the Phytochemical Compound Furanodienone against Human Non-Small Lung Cancer A-549 Cells

Mohammed F. Aldawsari, El-Sayed Khafagy, Khaled Almansour, 2022, Life.

Clinical Resistant Strains of Enterococci and Their Correlation to Reduced Susceptibility to Biocides: Phenotypic and Genotypic Analysis of Macrolides, Lincosamides, and Streptogramins

Jowaher S Alanazi, A. Moin, S. Tabrez, 2023, Antibiotics.

Efficacy of SPG-ODN 1826 Nanovehicles in Inducing M1 Phenotype through TLR-9 Activation in Murine Alveolar J774A.1 Cells: Plausible Nano-Immunotherapy for Lung Carcinoma

S. Alshahrani, Mohammed F. Aldawsari, El-Sayed Khafagy, 2021, International journal of molecular sciences.

B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice.

T. Ishida, H. Kiwada, Taro Shimizu, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon.

T. Ishida, Taro Shimizu, H. Sarhan, 2020, Journal of controlled release : official journal of the Controlled Release Society.

A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2018, Pharmaceutical Research.

Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs.

T. Ishida, H. Kiwada, Taro Shimizu, 2014, Toxicology and applied pharmacology.

Optimization of Potential Nanoemulgels for Boosting Transdermal Glimepiride Delivery and Upgrading Its Anti-Diabetic Activity

A. S. Abu Lila, Tarek M. Ibrahim, M. Abdallah, 2023, Gels.

Ocular Delivery of Bimatoprost-Loaded Solid Lipid Nanoparticles for Effective Management of Glaucoma

A. Moin, El-Sayed Khafagy, Ahmad J. Obaidullah, 2023, Pharmaceuticals.

The Co-Delivery of Oxaliplatin Abrogates the Immunogenic Response to PEGylated siRNA-Lipoplex

T. Ishida, H. Kiwada, Naoto Moriyoshi, 2013, Pharmaceutical Research.

Piperine-Loaded In Situ Gel: Formulation, In Vitro Characterization, and Clinical Evaluation against Periodontitis

A. Moin, El-Sayed Khafagy, Ahmad J. Obaidullah, 2023, Gels.

Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model

M. Matsunaga, T. Ishida, H. Kiwada, 2012, Drug Delivery and Translational Research.

Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.

M. Fukushima, H. Wada, C. Kato, 2016, International journal of oncology.

Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model: synergy or antagonism?

T. Ishida, H. Kiwada, A. S. Abu Lila, 2012, International journal of pharmaceutics.

Poly ε-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model

R. Banerjee, H. Arab, R. Osmani, 2022, Pharmaceutics.

Dual targeting multiwalled carbon nanotubes for improved neratinib delivery in breast cancer

Turki Al Hagbani, H. Gangadharappa, A. Moin, 2023, RSC advances.

Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing

T. Ishida, Taro Shimizu, A. S. Abu Lila, 2016, International journal of nanomedicine.

An Update on Emergent Nano-Therapeutic Strategies against Pediatric Brain Tumors

Asha P. Johnson, H. Gangadharappa, R. Osmani, 2024, Brain sciences.

Cefotaxime Mediated Synthesis of Gold Nanoparticles: Characterization and Antibacterial Activity

Turki Al Hagbani, A. Moin, El-Sayed Khafagy, 2022, Polymers.

The Anti-Virulence Activities of the Antihypertensive Drug Propranolol in Light of Its Anti-Quorum Sensing Effects against Pseudomonas aeruginosa and Serratia marcescens

S. Alshawwa, El-Sayed Khafagy, A. S. Abu Lila, 2023, Biomedicines.

Intra-tumor distribution of PEGylated liposome upon repeated injection: No possession by prior dose.

T. Ishida, H. Kiwada, A. S. Abu Lila, 2015, Journal of controlled release : official journal of the Controlled Release Society.