T. Ochiai

发表

Acid sphingomyelinase inhibition suppresses lipopolysaccharide‐mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium‐induced colitis in mice

R. Eyanagi, S. Shibuya, S. Soeda, 2007, Immunology.

Inhibition of lipopolysaccharide-induced release of interleukin-8 from intestinal epithelial cells by SMA, a novel inhibitor of sphingomyelinase and its therapeutic effect on dextran sulphate sodium-induced colitis in mice.

S. Shibuya, S. Soeda, A. Sakata, 2007, Cellular immunology.

Olefin polymerization behavior of titanium(IV) pyridine-2-phenolate-6- (σ-aryl) catalysts: Impact of "py-adjacent" and phenolate substituents

K. Lau, T. Ochiai, Po-Kam Lo, 2013 .

Plasminogen activator inhibitor-1 aids survival of neurites on neurons derived from pheochromocytoma (PC-12) cells

S. Koyanagi, T. Imatoh, S. Soeda, 2004, Neuroreport.

Release of plasminogen activator inhibitor‐1 from human astrocytes is regulated by intracellular ceramide

S. Soeda, T. Ochiai, H. Shimeno, 2000, Journal of neuroscience research.

Pharmacological studies on (4S)-1-methyl-3-[(2S)-2-[N-((1S)-1-ethoxycarbonyl-3-phenylpropyl)amino] propionyl]-2-oxo-imidazolidine-4-carboxylic acid hydrochloride (TA-6366), a new ACE inhibitor: I. ACE inhibitory and anti-hypertensive activities.

R. Ishida, T. Ochiai, M. Kubo, 1990, Japanese journal of pharmacology.

Chromatographic separation of oxy- and met-myoglobin on a DEAE-cellulose column.

K. Shikama, T. Ochiai, T. Gotoh, 1971, Journal of chromatography.

Molecular mechanism for neuro-protective effect of prosaposin against oxidative stress: its regulation of dimeric transcription factor formation.

R. Misasi, S. Soeda, M. Hiraiwa, 2008, Biochimica et biophysica acta.

Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of α-tocopherol

Y. Shoyama, Hiroyuki Tanaka, S. Soeda, 2004, Neuroscience Letters.

Studies on biologically active halogenated compounds. II. Chemical modifications of 6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone and the CNS depressant activities of related compounds.

Y. Yamada, R. Ishida, I. Inoue, 1979, Chemical & pharmaceutical bulletin.

Synthesis of telechelic olefin polymers via catalyzed chain growth on multinuclear alkylene zinc compounds.

Y. Usui, Jun-ichi Mohri, T. Shimazaki, 2013, Journal of the American Chemical Society.

FI Catalysts: A Molecular Zeolite for Olefin Polymerization

T. Ochiai, T. Fujita, H. Makio, 2010 .

Pharmacological studies on 6-amino-2-fluoromethyl-3-(O-tolyl)-4(3H)-quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity.

R. Ishida, T. Ochiai, 1982, Japanese journal of pharmacology.

Concise Synthesis of Fully-Substituted Furan, Pyrrole, Butenolide, and 2-Butene-4-lactam Esters

N. Iwasawa, T. Ochiai, K. Maeyama, 1998 .

Studies on biologically active halogenated compounds. 1. Synthesis and central nervous system depressant activity of 2-(fluoromethyl)-3-aryl-4(3H)-quinazolinone derivatives.

Y. Yamada, R. Ishida, I. Inoue, 1979, Journal of medicinal chemistry.

Effects of 1-morpholinoacetyl-2-methyl-3-phenyl-4-oxo-1,2,3,4-tetrahydro quinazoline hydrochloride (HQ-275) on alpha-naphtyl isothio-cyanate- and/or thioacetamide-induced liver damage in rats.

T. Ochiai, 1974, Japanese journal of pharmacology.

Effects of 1-morpholinoacetyl-2-methyl-3-phenyl-4-oxo-1, 2, 3, 4-tetrahydroquinazoline hydrochloride (HQ-275) on acute experimental hepatic injury induced by carbon tetrachloride in rats.

T. Ochiai, M. Hori, Y. Kowa, 1973, Japanese journal of pharmacology.

Relationship of HQ-275 to biliary excretion and portal blood flow in dogs.

T. Nagao, K. Yoshimoto, T. Ochiai, 1973, Japanese journal of pharmacology.

4-Oxo-1,2,3,4-tetrahydroquinazolines. 3. Synthesis and choleretic activity of quinazoline derivatives.

Y. Yamada, T. Ochiai, J. Tani, 1972, Journal of medicinal chemistry.

Pharmacology of a new hypnotic drug: HQ-355.

R. Ishida, T. Ochiai, Y. Kowa, 1972, Japanese journal of pharmacology.

Choleretic activities of 1-morpholinoacetyl-2-methyl-3-phenyl-4-oxo-1, 2, 3, 4-tetrahydro quinazoline hydrochloride (HQ-275).

T. Ochiai, K. Okumura, Y. Kowa, 1972, Japanese journal of pharmacology.

PHARMACOLOGICAL STUDIES ON 6-AMINO-2-FLUOROMETHYL-3-(O-TOLYL)-4(3H)-QUINAZOLINONE (AFLOQUALONE), A NEW CENTRALLY ACTING MUSCLE RELAXANT (I)

R. Ishida, T. Ochiai, 1981 .

Observation and Iodine Oxidation of the Protonated Anionic Propargyltungsten Species Formed in the Reaction of Fischer-Type Carbene Complexes with Alkynyllithiums

N. Iwasawa, T. Ochiai, K. Maeyama, 1997 .

Total Synthesis of the Furaquinocins

Keisuke Suzuki, Takeshi Saito, T. Ochiai, 1998 .

Crocin suppresses tumor necrosis factor-alpha-induced cell death of neuronally differentiated PC-12 cells.

Y. Shoyama, S. Soeda, H. Tanaka, 2001, Life sciences.

Pharmacological activities of crocin in saffron

K. Abe, H. Saito, Y. Shoyama, 2007, Journal of Natural Medicines.

Pharmacological studies on TA-6366, a new ACE inhibitor: II. Effect of long-term administration from the pre-hypertensive stage on blood pressure, relative heart weight and ACE activity of various tissues in spontaneously hypertensive rats (SHRs).

R. Ishida, T. Ochiai, M. Kubo, 1991, Japanese journal of pharmacology.

Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo.

Y. Shoyama, Hiroyuki Tanaka, R. Eyanagi, 2007, Biochimica et biophysica acta.

Studies on angiotensin converting enzyme inhibitors. 4. Synthesis and angiotensin converting enzyme inhibitory activities of 3-acyl-1-alkyl-2-oxoimidazolidine-4-carboxylic acid derivatives.

R. Ishida, T. Ochiai, M. Kubo, 1989, Journal of medicinal chemistry.

Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress

Y. Tsuji, S. Shibuya, S. Soeda, 2004, Neurochemistry International.

Studies on Angiotensin‐Converting Enzyme Inhibitors. Part 4. Synthesis and Angiotensin‐Converting Enzyme Inhibitory Activities of 3‐Acyl‐1‐alkyl‐2‐oxoimidazolidine‐4‐carboxylic Acid Derivatives.

R. Ishida, T. Ochiai, M. Kubo, 1989 .

Effects of psychotropic drugs on emotional behavior: exploratory behavior of naive rats in holed open field.

T. Ochiai, M. Nakama, Y. Kowa, 1972, Japanese journal of pharmacology.

CHOLESTEROL-INDEPENDENT, MAPK/ERK SIGNAL-MEDIATED SIMVASTATIN POTENTIATION OF NERVE GROWTH FACTOR-INDUCED NEURITE OUTGROWTH IN PC-12 CELLS

T. Ochiai, K. Fukuda, Masakazu Kasuya, 2008 .

Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis

Y. Shoyama, Hiroyuki Tanaka, S. Soeda, 2004, Neurochemistry International.

Promising pharmacological actions of croon in crocus sativus on the central nervous system

H. Saito, S. Morimoto, Y. Shoyama, 2003 .

Plasminogen activator inhibitor-1 aids nerve growth factor-induced differentiation and survival of pheochromocytoma cells by activating both the extracellular signal-regulated kinase and c-Jun pathways

S. Koyanagi, R. Eyanagi, S. Soeda, 2006, Neuroscience.

A behavioral pharmacological study of mafoprazine, a new phenylpiperazine derivative.

M. Yamamura, R. Ishida, T. Ochiai, 1988, Japanese journal of pharmacology.

Screening of an α-Amylase Inhibitor Peptide by Photolinker–Peptide Array

M. Okochi, Ryuji Kato, H. Honda, 2012, Bioscience, biotechnology, and biochemistry.

[Effects of afloqualone, a new centrally acting muscle relaxant, on DRL response and CER in rats (author's transl)].

M. Yamamura, R. Ishida, T. Ochiai, 1981, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Deficient release of plasminogen activator inhibitor-1 from astrocytes triggers apoptosis in neuronal cells.

S. Soeda, T. Ochiai, H. Shimeno, 2001, Brain research. Molecular brain research.