J. Simons

发表

Correction of the neuropathogenic human apolipoprotein E4 (APOE4) gene to APOE3 in vitro using synthetic RNA/DNA oligonucleotides (chimeraplasts)

J. S. Owen, A. Tagalakis, J. Dickson, 2007, Journal of Molecular Neuroscience.

Correction of the neuropathogenic human apolipoprotein E 4 gene ( APOE 4 ) to APOE 3 in vitro using synthetic RNA / DNA oligonucleotides ( chimeraplasts )

J. S. Owen, A. Tagalakis, J. Simons, 2005 .

Transgenic livestock.

J. Simons, R. B. Land, 2019, Journal of reproduction and fertility. Supplement.

Production of pharmaceutical proteins in milk

A. Archibald, I. Wilmut, A. Clark, 1991, Experientia.

Genetic manipulation of mammals and its application in reproductive biology.

I. Wilmut, M. Hooper, J. Simons, 1991, Journal of reproduction and fertility.

Developmental regulation of the sheep beta-lactoglobulin gene in the mammary gland of transgenic mice.

J. Simons, M. McClenaghan, A. Clark, 1991, Developmental genetics.

Milk composition and lactation of beta-casein-deficient mice.

Shylendra Kumar, A. Clarke, A. Law, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Manipulation of the Repertoire of Digestive Enzymes Secreted into the Gastrointestinal Tract of Transgenic Mice

M. Surani, Judith Hall, B. Hirst, 1993, Bio/Technology.

Linkage of adult α- and β-globin genes in X. laevis and gene duplication by tetraploidization

A. Jeffreys, Jeffrey G. Williams, V. Wilson, 1980, Cell.

Alteration of the quality of milk by expression of sheep β-lactoglobulin in transgenic mice

A. Clark, J. Simons, M. McClenaghan, 1987, Nature.

High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice.

A. Archibald, V. Hornsey, J. Simons, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Expression of Human Anti-Hemophilic Factor IX in the Milk of Transgenic Sheep

R. Lathe, C. Prowse, I. Wilmut, 1989, Bio/Technology.

Production of Human α 1 -Antitrypsin in The Milk of Transgenic Sheep and Mice: Targeting Expression of cDNA Sequences to The Mammary Gland

A. Archibald, I. Wilmut, A. Clark, 1991 .

Targeting expression to the mammary gland: intronic sequences can enhance the efficiency of gene expression in transgenic mice

A. Archibald, A. Clark, C. Whitelaw, 1991, Transgenic Research.

Rescuing Transgene Expression by Co-Integration

A. Clark, R. Wallace, J. Simons, 1992, Bio/Technology.

Gene Transfer into Sheep

R. Lathe, A. Archibald, I. Wilmut, 1988, Bio/Technology.

Lack of RNA–DNA oligonucleotide (chimeraplast) mutagenic activity in mouse embryos

A. Tagalakis, J. Simons, J. Owen, 2005, Molecular reproduction and development.

Gene expression in the mammary gland.

J. Simons, M. McClenaghan, A. Clark, 1990, Journal of reproduction and fertility.

Position-independent expression of the ovine beta-lactoglobulin gene in transgenic mice.

C. Whitelaw, J. Simons, M. McClenaghan, 1992, The Biochemical journal.

Enhancing the efficiency of transgene expression.

A. Archibald, A. Clark, C. Whitelaw, 1993, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Methods of gene transfer and their potential use to modify milk composition

A. Archibald, I. Wilmut, A. Clark, 1990 .

The germline manipulation of livestock: progress during the past five years.

A. Archibald, I. Wilmut, B. Whitelaw, 1990 .

Autocrine regulation of milk protein secretion

A. Clark, C. Addey, C. Wilde, 1994 .

The secretory pathway for milk protein secretion and its regulation

C. Wilde, M. D. Turner, R. Burgoyne, 1995 .

Oligonucleotide-directed gene-editing technology: mechanisms and future prospects

Ioannis Papaioannou, James S Owen, J Paul Simons, 2012, Expert opinion on biological therapy.

Validation of oligonucleotide-mediated gene editing

P. Disterer, J. Simons, J. Owen, 2009, Gene Therapy.

Exon skipping of hepatic APOB pre-mRNA with splice-switching oligonucleotides reduces LDL cholesterol in vivo.

P. Disterer, B. Khoo, S. Waddington, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein

J. Simons, I. Papaioannou, J. Owen, 2012, Cardiology research and practice.

Linkage of adult alpha- and beta-globin genes in X. laevis and gene duplication by tetraploidization.

J. Williams, V. Wilson, J. Simons, 1980, Cell.

LINKAGE OF ADULT ALPHA-GLOBIN AND BETA-GLOBIN GENES IN X-LAEVIS AND GENE DUPLICATION BY TETRAPLOIDIZATION

J. Simons, Wilson, A. Jeffreys, 1980 .

Cloning and molecular characterization of a cross-homologous zinc finger locus ZNF204.

M. Fox, J. Dooley, A. Walker, 1998, Genomics.

Modification of milk composition.

A. Archibald, I. Wilmut, A. Clark, 1990, Journal of reproduction and fertility. Supplement.

Structural Diversity Despite Strong Evolutionary Conservation in the 5′-Untranslated Region of the P-Type Dystrophin Transcript

N. Noro, E. Barnard, D. Górecki, 2001, Molecular and Cellular Neuroscience.

The molecular manipulation of milk

C. Watson, A. Archibald, I. Wilmut, 1990 .

The molecular manipulation of milk composition.

C. Prowse, A. Archibald, A. Clark, 1989, Genome.

Characterisation of the alleles encoding ovine ß-lactoglobulins A and B

J. Simons, M. McClenaghan, A. Clark, 1990 .

The effects of terminal heterologies on gene targeting by insertion vectors in embryonic stem cells.

Satish Kumar, J. P. Simons, J. Simons, 1993, Nucleic acids research.

Mammary development and milk secretion in transgenic mice expressing the sheep beta-lactoglobulin gene.

M. Kerr, A. Clark, C. Knight, 1992, The Biochemical journal.

Modification of Milk by Gene Transfer

J. Paul Simons, J. Simons, 1989 .