E. Cansby

发表

Silencing of STE20‐type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet‐induced nonalcoholic fatty liver disease

J. Borén, M. Mahlapuu, S. Booten, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained

U. Smith, M. Mahlapuu, A. Nerstedt, 2014, Molecular and Cellular Endocrinology.

Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective

Jonathan L. Robinson, M. Mahlapuu, L. Svensson, 2022, Communications Biology.

Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

F. Bäckhed, J. Borén, U. Smith, 2015, Diabetes.

Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH

J. Borén, U. Smith, M. Mahlapuu, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease.

J. Borén, M. Mahlapuu, J. Nyström, 2020, JCI insight.

GCKIII kinases in lipotoxicity: Roles in NAFLD and beyond

M. Mahlapuu, Mara Caputo, E. Cansby, 2022, Hepatology communications.

Inhibition of MAP4K4 signaling initiates metabolic reprogramming to protect hepatocytes from lipotoxic damage

M. Blüher, M. Mahlapuu, J. Höög, 2022, Journal of lipid research.

Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle

U. Smith, M. Laakso, A. Stančáková, 2012, Diabetologia.

Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice

M. Mahlapuu, Joana Real, H. Marschall, 2017, The Journal of endocrinology.

Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver[S]

J. Borén, D. Mashek, M. Mahlapuu, 2019, Journal of Lipid Research.

Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes

U. Smith, M. Mahlapuu, A. Nerstedt, 2013, Molecular and Cellular Endocrinology.

Silencing of STE20-type kinase TAOK1 confers protection against hepatocellular lipotoxicity through metabolic rewiring

M. Mahlapuu, K. Kilk, S. Kumari, 2023, Hepatology communications.

STE20-type kinase TAOK3 regulates hepatic lipid partitioning

M. Blüher, M. Mahlapuu, H. Marschall, 2021, Molecular metabolism.

STE20‐Type Protein Kinase MST4 Controls NAFLD Progression by Regulating Lipid Droplet Dynamics and Metabolic Stress in Hepatocytes

J. Borén, M. Blüher, M. Mahlapuu, 2021, Hepatology communications.

Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high‐fat diet

J. Borén, U. Smith, P. Carlsson, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)

U. Smith, M. Mahlapuu, A. Nerstedt, 2010, Diabetologia.

Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans

J. Borén, M. Blüher, C. Sihlbom, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans

J. Borén, M. Blüher, M. Mahlapuu, 2016, Diabetologia.

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

F. Bäckhed, J. Borén, B. Johansson, 2016, Diabetologia.

Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease

J. Borén, M. Mahlapuu, L. Svensson, 2018, Cellular and molecular gastroenterology and hepatology.

Regulation of metabolism and inflammation by two protein kinases - AMPK and STK25

E. Cansby, 2014 .

STK25 regulates oxidative capacity and metabolic efficiency in adipose tissue.

J. Borén, S. Enerbäck, M. Mahlapuu, 2018, The Journal of endocrinology.

STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia

J. Borén, M. Mahlapuu, P. Parini, 2018, Arteriosclerosis, thrombosis, and vascular biology.

STE20‐type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies

M. Mahlapuu, H. Marschall, Ying Xia, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways

M. Mahlapuu, S. Kumari, H. Marschall, 2021, Cellular and molecular gastroenterology and hepatology.

Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice

M. Mahlapuu, H. Marschall, E. Cansby, 2023, Molecular Medicine.

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice

J. Borén, N. Stefan, M. Mahlapuu, 2017, Hepatology Communications.

Genetic Ablation of STE20-Type Kinase MST4 Does Not Alleviate Diet-Induced MASLD Susceptibility in Mice

M. Mahlapuu, E. Cansby, M. Amrutkar, 2024, International journal of molecular sciences.