Q. Fang

发表

Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines

N. Zhang, Ting Zhang, Run Zhang, 2018, Journal of Neuroinflammation.

Spinal microglia-derived TNF promotes the astrocytic JNK/CXCL1 pathway activation in a mouse model of burn pain

Run Zhang, Biao Xu, Meng-na Zhang, 2022, Brain, Behavior, and Immunity.

GpTx‐1 and [Ala5, Phe6, Leu26, Arg28]GpTx‐1, two peptide NaV1.7 inhibitors: analgesic and tolerance properties at the spinal level

Ting Zhang, Run Zhang, Weidong Zhao, 2018, British journal of pharmacology.

Pharmacological characterization of rat VD-hemopressin(α), an α-hemoglobin-derived peptide exhibiting cannabinoid agonist-like effects in mice

Rui Wang, Zi-long Wang, Ting Zhang, 2017, Neuropeptides.

TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor

P. Parekh, Fan Wang, R. Gereau, 2014, PAIN®.

OFP011 Cyclic Peptide as a Multifunctional Agonist for Opioid/Neuropeptide FF Receptors with Improved Blood-Brain Barrier Penetration.

S. F. Rizvi, Run Zhang, Biao Xu, 2022, ACS chemical neuroscience.

Effects of neuropeptide FF and related peptides on the antinociceptive activities of VD-hemopressin(α) in naive and cannabinoid-tolerant mice.

N. Zhang, Rui Wang, Zi-long Wang, 2015, European journal of pharmacology.

The anti-inflammatory potential of neuropeptide FF in vitro and in vivo

N. He, Rui Wang, Q. Fang, 2013, Peptides.

Inhibitory effects of antibiotic-induced gut microbiota depletion on acute itch behavior in mice

Jie Feng, Run Zhang, Meng-na Zhang, 2022, Brain Research Bulletin.

VF-13, a chimeric peptide of VD-hemopressin(α) and neuropeptide VF, produces potent antinociception with reduced cannabinoid-related side effects

Run Zhang, Biao Xu, Meng-na Zhang, 2020, Neuropharmacology.

Central and peripheral modulation of gastrointestinal transit in mice by DN‐9, a multifunctional opioid/NPFF receptor agonist

Yu Qiu, Run Zhang, Biao Xu, 2020, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Antinociceptive effects of the endogenous cannabinoid peptide agonist VD-hemopressin(β) in mice

Ting Zhang, Run Zhang, Weidong Zhao, 2018, Brain Research Bulletin.

Activation of NPFF2 receptor stimulates neurite outgrowth in Neuro 2A cells through activation of ERK signaling pathway

N. Zhang, Rui Wang, Zi-long Wang, 2016, Peptides.

The hypotensive effect of intrathecally injected (m)VD-hemopressin(α) in urethane-anesthetized rats

Rui Wang, Zi-long Wang, Q. Fang, 2014, Peptides.

Development of Multifunctional and Orally Active Cyclic Peptide Agonists of Opioid/Neuropeptide FF Receptors that Produce Potent, Long-Lasting, and Peripherally Restricted Antinociception with Diminished Side Effects.

Run Zhang, Biao Xu, Meng-na Zhang, 2021, Journal of medicinal chemistry.

Central administrations of hemopressin and related peptides inhibit gastrointestinal motility in mice

N. Li, Q. Fang, R. Wang, 2016, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Structure-Based Optimization of Multifunctional Agonists for Opioid and Neuropeptide FF Receptors with Potent Nontolerance Forming Analgesic Activities.

Rui Wang, Zi-long Wang, Hong Yu, 2016, Journal of medicinal chemistry.

Neuropeptide FF activates ERK and NF kappa B signal pathways in differentiated SH-SY5Y cells

Y. Zhuang, Kairong Wang, N. He, 2012, Peptides.

Peripheral and central sites of action for anti‐allodynic activity induced by the bifunctional opioid/NPFF receptors agonist BN‐9 in inflammatory pain model

Rui Wang, Zi-long Wang, Ting Zhang, 2017, European journal of pharmacology.

Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch*

Jennifer Y. Zhang, A. MacLeod, W. Liedtke, 2016, The Journal of Biological Chemistry.

Effects of nociceptin (13–17) in pain modulation at supraspinal level in mice

Rui Wang, Huaping Wu, Q. Fang, 2002, Neuroscience Letters.

Study in vitro and in vivo of nociceptin/orphanin FQ(1–13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3

Rui Wang, Q. Fang, Qiang Chen, 2004, Peptides.

Spinal administration of the multi-functional opioid/neuropeptide FF agonist BN-9 produced potent antinociception without development of tolerance and opioid-induced hyperalgesia.

Run Zhang, Biao Xu, Qinqin Zhang, 2020, European journal of pharmacology.

The multifunctional peptide DN‐9 produced peripherally acting antinociception in inflammatory and neuropathic pain via μ‐ and κ‐opioid receptors

Yu Qiu, W. Liedtke, Rui Wang, 2020, British journal of pharmacology.

BN‐9, a chimeric peptide with mixed opioid and neuropeptide FF receptor agonistic properties, produces nontolerance‐forming antinociception in mice

Yu-Long Sun, Rui Wang, Zi-long Wang, 2016, British journal of pharmacology.

Systemic administration of the bifunctional opioid/neuropeptide FF receptors agonist BN‐9 produced peripheral antinociception in preclinical mouse models of pain

Ting Zhang, Weidong Zhao, Biao Xu, 2018, European journal of pharmacology.

Neuropeptide FF receptor antagonist, RF9, attenuates the fever induced by central injection of LPS in mice

Rui Wang, Q. Fang, Jing Ma, 2011, Peptides.

Neuropeptide FF receptors antagonist, RF9, attenuates opioid-evoked hypothermia in mice

Rui Wang, Q. Fang, Feng He, 2008, Peptides.

Neuropeptide FF receptors exert contractile activity via inhibition of nitric oxide release in the mouse distal colon

Min Chang, Rui Wang, Q. Fang, 2005, Peptides.

Inhibition of neuropeptide FF (NPFF)-induced hypothermia and anti-morphine analgesia by RF9, a new selective NPFF receptors antagonist

Rui Wang, Q. Fang, Feng He, 2008, Regulatory Peptides.

Pharmacological effects of the dansylated neuropeptide FF analogues on body temperature and morphine analgesia

Rui Wang, Bang-zhi Zhang, Q. Fang, 2007, Neuropeptides.

In vivo inhibition of neuropeptide FF agonism by BIBP3226, an NPY Y1 receptor antagonist

Ya-li Peng, Min Chang, Rui Wang, 2006, Peptides.

Neuropeptide FF attenuates the acquisition and the expression of conditioned place aversion to endomorphin-2 in mice

Rui Wang, Zi-long Wang, Q. Fang, 2013, Behavioural Brain Research.

In vitro and in vivo studies of dansylated compounds, the putative agonists and antagonists on neuropeptide FF receptors

Ya-li Peng, Min Chang, Rui Wang, 2006, Peptides.

Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance

Rui Wang, Zi-long Wang, Hong Yu, 2016, Neuropharmacology.

Opposite Effects of Neuropeptide FF on Central Antinociception Induced by Endomorphin-1 and Endomorphin-2 in Mice

Rui Wang, Zi-long Wang, Q. Fang, 2014, PloS one.

Synthesis and Biological Characterization of Cyclic Disulfide-Containing Peptide Analogs of the Multifunctional Opioid/Neuropeptide FF Receptor Agonists That Produce Long-Lasting and Nontolerant Antinociception.

Yulong Sun, Ting Zhang, Run Zhang, 2020, Journal of medicinal chemistry.

NaV1.7 Channel Blocker [Ala5, Phe6, Leu26, Arg28]GpTx-1 Attenuates CFA-induced Inflammatory Hypersensitivity in Rats via Endogenous Enkephalin Mechanism.

Run Zhang, Biao Xu, Qinqin Zhang, 2022, The journal of pain.

Spinal DN-9, a peptidic multifunctional opioid/neuropeptide FF agonist produced potent nontolerance forming analgesia with limited side effects.

Changyu Jiang, Ting Zhang, Zilong Wang, 2020, The journal of pain : official journal of the American Pain Society.

Involvement of Sensory Neurone-TRPV4 in Acute and Chronic Itch Behaviours

Yong Chen, Zilong Wang, Q. Fang, 2022, Acta dermato-venereologica.

Discovery of two novel branched peptidomimetics containing endomorphin-2 and RF9 pharmacophores: Synthesis and neuropharmacological evaluation.

Ting Zhang, Run Zhang, Weidong Zhao, 2019, Bioorganic & medicinal chemistry.

Analgesic tolerance and cross-tolerance to the cannabinoid receptors ligands hemopressin, VD-hemopressin(α) and WIN55,212-2 at the supraspinal level in mice

Rui Wang, Zi-long Wang, Q. Fang, 2014, Neuroscience Letters.

Antinociceptive Effects of Central Administration of the Endogenous Cannabinoid Receptor Type 1 Agonist VDPVNFKLLSH-OH [(m)VD-hemopressin(α)], an N-Terminally Extended Hemopressin Peptide

Rui Wang, Zi-long Wang, Q. Fang, 2014, Journal of Pharmacology and Experimental Therapeutics.

Effects of neuropeptide FF system on CB1 and CB2 receptors mediated antinociception in mice

N. He, Rui Wang, Zi-long Wang, 2012, Neuropharmacology.

OCP002, a Mixed Agonist of Opioid and Cannabinoid Receptors, Produces Potent Antinociception With Minimized Side Effects

Run Zhang, Weidong Zhao, Biao Xu, 2022, Anesthesia and analgesia.

CB1 cannabinoid receptor agonist mouse VD-hemopressin(α) produced supraspinal analgesic activity in the preclinical models of pain

Rui Wang, Ting Zhang, Run Zhang, 2018, Brain Research.

Pressor and tachycardic responses to intrathecal administration of neuropeptide FF in anesthetized rats

Rui Wang, Q. Fang, Ning Li, 2010, Peptides.

Cardiovascular effects of intravenous administered 26RFa, a novel RFamide peptide ligand for GPR103, in anaesthetised rats.

Rui Wang, Q. Fang, Ning Li, 2009, European journal of pharmacology.

NOP01, a NOP receptor agonist, produced potent and peripherally restricted antinociception in a formalin-induced mouse orofacial pain model

Run Zhang, Biao Xu, Qinqin Zhang, 2021, Neuropeptides.

Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice

Rui Wang, Zi-long Wang, Q. Fang, 2012, Behavioural Brain Research.

Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptor.

Yu Qiu, Ting Zhang, Run Zhang, 2021, European journal of pharmacology.

Development and validation of a reversed phase liquid chromatographic method with fluorescence detection for the pharmacokinetic study of a new chimeric peptide

Lin Li, Chencheng Fan, Rui Wang, 2016 .

Synergistic interaction between DAMGO-NH2 and NOP01 in peripherally acting antinociception in two mouse models of formalin pain

Qinqin Zhang, Jian Xiao, Dan Chen, 2023, Peptides.

Analgesic activities of the mixed opioid and NPFF receptors agonist DN-9 in a mouse model of formalin-induced orofacial inflammatory pain

Ting Zhang, Weidong Zhao, Biao Xu, 2018, Peptides.

Single Nucleotide Polymorphisms and Haplotype of Four Genes Encoding Cardiac Ion Channels in Chinese and their Association with Arrhythmia

Songnian Hu, M. Qi, Yu Zhang, 2008, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

Identification of a pH-Responsive Peptide-Paclitaxel Conjugate as a Novel Drug with Improved Therapeutic Potential.

Haixia Zhang, S. F. Rizvi, Q. Fang, 2023, Journal of medicinal chemistry.

Neuropeptide VF Enhances Cannabinoid Agonist WIN55,212-2-Induced Antinociception in Mice

Rui Wang, Zi-long Wang, Q. Fang, 2015, Anesthesia and analgesia.

Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines

N. Zhang, Ting Zhang, Run Zhang, 2018, Journal of neuroinflammation.

NPFF2 receptor is involved in the modulatory effects of neuropeptide FF for macrophage cell line.

Y. Zhuang, Kairong Wang, N. He, 2014, Protein and peptide letters.