Y. Yamashita

发表

Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists.

T. Nishimaki-Mogami, K. Gohda, N. Teno, 2017, Bioorganic & medicinal chemistry.

Multiple Molecular Forms of Acetylcholine Receptors in Cultured Skeletal Muscle Cells: Subcellular Localization and Characterization

H. Sugiyama, Y. Yamashita, F. Murakami, 1982, Journal of neurochemistry.

Discovery of Orally Active and Nonsteroidal Farnesoid X Receptor (FXR) Antagonist with Propensity for Accumulation and Responsiveness in Ileum.

K. Fujimori, K. Oda, Arisa Masuda, 2021, ACS medicinal chemistry letters.

2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease.

N. Asano, S. Nakagawa, A. Kato, 2010, Bioorganic & medicinal chemistry.

Identification of potent farnesoid X receptor (FXR) antagonist showing favorable PK profile and distribution toward target tissues: Comprehensive understanding of structure-activity relationship of FXR antagonists.

K. Fujimori, T. Nishimaki-Mogami, K. Oda, 2019, Bioorganic & medicinal chemistry.

Synthesis of Novel Farnesoid X Receptor Agonists and Validation of Their Efficacy in Activating Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells into Osteoblasts

K. Fujimori, K. Gohda, N. Teno, 2019, Molecules.

Dual Agonist of Farnesoid X Receptor and Takeda G Protein‐Coupled Receptor 5 Inhibits Hepatitis B Virus Infection In Vitro and In Vivo

K. Umezawa, T. Wakita, K. Watashi, 2021, Hepatology.

5-Alkylresorcinol glucosides from the leaves of Grevillea robusta Allan Cunningham

Y. Takeda, H. Otsuka, K. Matsunami, 2010, Journal of Natural Medicines.

Palladium-catalyzed Mizoroki–Heck-type reactions of chalcogenonium trifluoromethanesulfonates

Toshio Shimizu, Y. Yamashita, K. Hirabayashi, 2009 .

Nonacidic Chemotype Possessing N-Acylated Piperidine Moiety as Potent Farnesoid X Receptor (FXR) Antagonists.

K. Fujimori, T. Nishimaki-Mogami, K. Gohda, 2018, ACS medicinal chemistry letters.

Synthesis of novel ferrocenyl sugars and their antimalarial activities.

Y. Wataya, H. S. Kim, Y. Yamashita, 2000, Bioorganic & medicinal chemistry letters.

Synthesis of (-)-trolline, (-)-crispine A and (-)-crispine E

Y. Yamashita, T. Kanemitsu, T. Itoh, 2007 .

L-DMDP, L-homoDMDP and their C-3 fluorinated derivatives: synthesis and glycosidase-inhibition.

G. Fleet, A. Kato, Y. Yamashita, 2011, Organic & biomolecular chemistry.

Synthesis of phenylalkyl-substituted polyhydroxypiperidines as potent inhibitors for α-l-fucosidase

Y. Tezuka, N. Toyooka, Kenji Sugimoto, 2013 .

Nanosized starlike molecules. Synthesis and optical properties of 2,4,6-tris(disilanylenebithienylene)-1,3,5-triazine derivatives

J. Ohshita, Y. Ooyama, Y. Yamashita, 2012 .

Total synthesis of the antibiotic BE-43472B.

Keisuke Suzuki, Y. Hirano, H. Takikawa, 2013, Angewandte Chemie.

Total Synthesis of Bis-anthraquinone Antibiotic BE-43472B

Keisuke Suzuki, Y. Hirano, H. Takikawa, 2018 .

Mutagenic Activity of Autoxidized Linolenic and Linoleic Acid

Y. Yamashita, Tsutomu Yamaguchi, 1979 .

Grevillosides A-F: glucosides of 5-alkylresorcinol derivatives from leaves of Grevillea robusta.

Y. Takeda, H. Otsuka, K. Matsunami, 2008, Phytochemistry.

N1-Substituted benzimidazole scaffold for farnesoid X receptor (FXR) agonists accompanying prominent selectivity against vitamin D receptor (VDR).

K. Fujimori, K. Oda, Arisa Masuda, 2020, Bioorganic & medicinal chemistry.

Mutagenicity of Hydroperoxides of Fatty Acids and Some Hydrocarbons

Y. Yamashita, Tsutomu Yamaguchi, 1980 .

Novel type of plasmin inhibitors: providing insight into P4 moiety and alternative scaffold to pyrrolopyrimidine.

Y. Tsuda, Arisa Masuda, T. Otsubo, 2015, Bioorganic & medicinal chemistry.

Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin.

Y. Tsuda, T. Otsubo, K. Gohda, 2014, Bioorganic & medicinal chemistry.

Protective effects of dietary 1,5-anhydro-D-glucitol as a blood glucose regulator in diabetes and metabolic syndrome.

F. Ishikawa, K. Takeshita, A. Kato, 2013, Journal of agricultural and food chemistry.

Concentration of mRNA for the natriuretic peptide receptor-C in hypertrophic chondrocytes of the fetal mouse tibia.

S. Hirose, H. Hagiwara, Y. Yamashita, 2000, Journal of biochemistry.

Proteolytic Enzymes in Green Asparagus, Kiwi Fruit and Miut: Occurrence and Partial Characterization

Y. Yamashita, Tsutomu Yamaguchi, Imao Takeda, 1982 .

Association of Phosphatidylcholine with Soybean 7S Globulin and Its Effect on The Protein Conformation

M. Kito, Y. Yamashita, R. Kanamoto, 1979 .

Design and identification of a new farnesoid X receptor (FXR) partial agonist by computational structure-activity analysis: Ligand-induced H8 helix fluctuation in the ligand-binding domain of FXR may lead to partial agonism.

K. Fujimori, Arisa Masuda, K. Gohda, 2021, Bioorganic & medicinal chemistry letters.

MULTIPLE FORMS OF INTRACELLULAR α-BUNGAROTOXIN BINDING COMPONENTS WITH DIFFERENT MOLECULAR SIZES IN CULTURED SKELETAL MUSCLE CELLS

H. Sugiyama, Y. Yamashita, S. Yamagishi, 1983 .

Discovery of FXR/PPARγ dual partial agonist.

K. Fujimori, K. Oda, Arisa Masuda, 2023, Bioorganic & medicinal chemistry.

Activating Effect of Several Enzyme-Proteins on the Mutagenicity of Amino-thiol Compounds

Y. Yamashita, Tsutomu Yamaguchi, 1981 .

Characterization of putative nicotinic acetylcholine receptors solubilized from rat brains

H. Sugiyama, Y. Yamashita, 1986, Brain Research.

Tritium labeling of alpha-neurotoxins with N-succinimidyl[3H]propionate.

H. Sugiyama, Y. Yamashita, 1981, Journal of biochemistry.