J. P. Maikhuri

发表

N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition.

Mala Singh, P. Shukla, Shagun Krishna, 2015, European journal of medicinal chemistry.

Innovative Disulfide Esters of Dithiocarbamic Acid as Women‐Controlled Contraceptive Microbicides: A Bioisosterism Approach

S. Sankhwar, P. Shukla, Nidhi Singh, 2015, ChemMedChem.

Inflammation driven tumor‐like signaling in prostatic epithelial cells by sexually transmitted Trichomonas vaginalis

B. Kushwaha, J. P. Maikhuri, G. Gupta, 2020, International journal of urology : official journal of the Japanese Urological Association.

Labda‐8(17),12,14‐trien‐19‐oic Acid Contained in Fruits of Cupressus sempervirens Suppresses Benign Prostatic Hyperplasia in Rat and In Vitro Human Models Through Inhibition of Androgen and STAT‐3 Signaling

K. Arya, Vishal Singh, M. F. Khan, 2014, Phytotherapy research : PTR.

Designed modulation of sex steroid signaling inhibits telomerase activity and proliferation of human prostate cancer cells.

Atul Kumar, A. Dwivedi, Siddhartha Sharma, 2014, Toxicology and applied pharmacology.

Novel metronidazole-chalcone conjugates with potential to counter drug resistance in Trichomonas vaginalis.

D. Rawat, U. C. Rajesh, B. Kushwaha, 2014, European journal of medicinal chemistry.

Selective estrogen receptor modulators regulate stromal proliferation in human benign prostatic hyperplasia by multiple beneficial mechanisms—action of two new agents

Rajeev Kumar, Ashish Jain, V. Verma, 2012, Investigational New Drugs.

Evaluation of STS-557 as an oral contraceptive in male rat.

B. S. Setty, J. P. Maikhuri, A. Srivastava, 1987, Contraception.

2-Methyl-4/5-nitroimidazole derivatives potentiated against sexually transmitted Trichomonas: Design, synthesis, biology and 3D-QSAR study.

Nidhi Singh, M. Siddiqi, Sonal Gupta, 2016, European journal of medicinal chemistry.

Combining a synthetic spermicide with a natural trichomonacide for safe, prophylactic contraception.

L. Kumar, Ashish Jain, Vishal Singh, 2014, Human reproduction.

Design, synthesis and biological profiling of aryl piperazine based scaffolds for the management of androgen sensitive prostatic disorders

Nidhi Singh, S. Yadav, S. Jaiswal, 2016 .

Arylpiperazines for management of benign prostatic hyperplasia: design, synthesis, quantitative structure-activity relationships, and pharmacokinetic studies.

Kirti, Y. S. Prabhakar, Ashish Jain, 2011, Journal of medicinal chemistry.

Designed Chemical Intervention with Thiols for Prophylactic Contraception

Vikas K. Sharma, Lokesh Kumar, L. Kumar, 2013, PloS one.

Novel Trichomonacidal Spermicides

S. K. Jain, Vishal Singh, N. Lal, 2011, Antimicrobial Agents and Chemotherapy.

Imidazole derivatives as possible microbicides with dual protection.

P. Shukla, Ashish Jain, N. Lal, 2010, European journal of medicinal chemistry.

Synthesis of benzenepropanamine analogues as non-detergent spermicides with antitrichomonas and anticandida activities.

M. Singh, P. Shukla, P. Tiwari, 2006, Bioorganic & medicinal chemistry.

The spermicidal and antitrichomonas activities of SSRI antidepressants.

M. Singh, Vinay V. Kumar, P. Tiwari, 2006, Bioorganic & medicinal chemistry letters.

Sensitization of androgen refractory prostate cancer cells to anti-androgens through re-expression of epigenetically repressed androgen receptor – Synergistic action of quercetin and curcumin

L. Kumar, S. Mohanty, J. P. Maikhuri, 2016, Molecular and Cellular Endocrinology.

Seasonal variations in daily sperm production rate of rhesus and bonnet monkeys

B. S. Setty, J. P. Maikhuri, G. Gupta, 2000, Journal of medical primatology.

In search of new chemical entities with spermicidal and anti-HIV activities.

S. Batra, A. Bhaduri, S. Srivastava, 1999, Bioorganic & medicinal chemistry.

Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology.

P. Shukla, Lokesh Kumar, L. Kumar, 2016, European journal of medicinal chemistry.

Ammonium salts of carbamodithioic acid as potent vaginal trichomonacides and fungicides.

P. Shukla, S. Yadav, L. Kumar, 2016, International journal of antimicrobial agents.

Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies.

Shagun Krishna, M. Siddiqi, N. Lal, 2015, Bioorganic & medicinal chemistry letters.

Design and synthesis of substituted morpholin/piperidin-1-yl-carbamodithioates as promising vaginal microbicides with spermicidal potential.

Vikas Kumar, P. Shukla, Sonal Gupta, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents.

Ashish Jain, A. Dwivedi, S. Paliwal, 2012, Bioorganic & medicinal chemistry letters.

Potentiating Metronidazole Scaffold against Resistant Trichomonas: Design, Synthesis, Biology and 3D-QSAR Analysis.

S. Jain, Lokesh Kumar, L. Kumar, 2012, ACS medicinal chemistry letters.

Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception.

Sumit Kumar, P. Shukla, Ashish Jain, 2011, Bioorganic & medicinal chemistry letters.

Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides.

P. Shukla, Ashish Jain, L. Kumar, 2008, European journal of medicinal chemistry.

Design and synthesis of γ-butyrolactone derivatives as potential spermicidal agents.

G. Pandey, L. Kumar, A. Dwivedi, 2014, Bioorganic & medicinal chemistry letters.

Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies.

Vikas Kumar, P. Shukla, L. Kumar, 2013, European journal of medicinal chemistry.

The dynamics of gene expression during and post meiosis sets the sperm agenda

S. Yadav, J. P. Maikhuri, G. Gupta, 2019, Molecular reproduction and development.

Design and synthesis of coumarin–glyoxal hybrids for spermicidal and antimicrobial actions: a dual approach to contraception

A. Dwivedi, Swati Gupta, S. Sankhwar, 2016 .

Mechanism of action of some acrylophenones, quinolines and dithiocarbamate as potent, non-detergent spermicidal agents.

B. S. Setty, A. Dwivedi, J. P. Maikhuri, 2003, Contraception.

Disulfiram and its novel derivative sensitize prostate cancer cells to the growth regulatory mechanisms of the cell by re‐expressing the epigenetically repressed tumor suppressor—estrogen receptor β

S. Yadav, N. Lal, V. Verma, 2016, Molecular carcinogenesis.

Oleanolic-bioenhancer coloaded chitosan modified nanocarriers attenuate breast cancer cells by multimode mechanism and preserve female fertility.

Shweta Sharma, P. Dwivedi, P. Mishra, 2017, International journal of biological macromolecules.

A unique dithiocarbamate chemistry during design & synthesis of novel sperm-immobilizing agents.

P. Shukla, Lokesh Kumar, N. Lal, 2014, Organic and biomolecular chemistry.

Substituted carbamothioic amine-1-carbothioic thioanhydrides as novel trichomonicidal fungicides: Design, synthesis, and biology.

P. Shukla, N. Srivastava, Shagun Krishna, 2018, European journal of medicinal chemistry.

Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents.

P. Srivastava, P. Shukla, A. Dwivedi, 2007, Bioorganic & medicinal chemistry.

Novel disulphide esters of carbothioic acid as potent, non-detergent spermicides with low toxicity to Lactobacillus and HeLa cells in vitro.

A. Dwivedi, V. K. Bajpai, K. Mitra, 2007, Human reproduction.

In vitro testing of rationally designed spermicides for selectively targeting human sperm in vagina to ensure safe contraception.

Ashish Jain, A. Dwivedi, V. K. Bajpai, 2009, Human reproduction.

Discovery of substituted isoxazolecarbaldehydes as potent spermicides, acrosin inhibitors and mild anti-fungal agents.

S. Batra, P. Shukla, V. Singh, 2005, Human reproduction.

Effect of spermicides on Lactobacillus acidophilus in vitro-nonoxynol-9 vs. Sapindus saponins.

P. Ojha, J. P. Maikhuri, G. Gupta, 2003, Contraception.

Synergistic chemoprotective mechanisms of dietary phytoestrogens in a select combination against prostate cancer.

Ashish Jain, Rajeev Kumar, V. Verma, 2011, The Journal of nutritional biochemistry.

Functional attenuation of human sperm by novel, non-surfactant spermicides: precise targeting of membrane physiology without affecting structure.

S. Batra, Rajeev Kumar, Ashish Jain, 2010, Human reproduction.

Substituted acrylophenones and related mannich bases as possible spermicides and inhibitors of HIV envelope glycoprotein-CD4 interaction.

A. Dwivedi, S. Habib, Satyawan Singh, 2002, European journal of medicinal chemistry.

Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines.

R. Konwar, Hamidullah, Sonal Gupta, 2016, Bioorganic & medicinal chemistry letters.

Spermicidal activity of bivittoside D from Bohadschia vitiensis.

M. N. Srivastava, S. Mishra, V. Lakshmi, 2008, Archives of medical research.

The thermo-sensitive gene expression signatures of spermatogenesis

S. Yadav, L. Kumar, B. Kushwaha, 2018, Reproductive Biology and Endocrinology.

Energy Utilization for Survival and Fertilization—Parsimonious Quiescent Sperm Turn Extravagant on Motility Activation in Rat1

S. Yadav, L. Kumar, V. Verma, 2016, Biology of reproduction.

Apigenin manipulates the ubiquitin–proteasome system to rescue estrogen receptor-β from degradation and induce apoptosis in prostate cancer cells

S. Yadav, Vishal Singh, V. Verma, 2015, European Journal of Nutrition.

Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression.

Nidhi Singh, S. Yadav, M. Siddiqi, 2017, European journal of medicinal chemistry.

Changes in daily sperm production rate in rats under the influence of a potent antispermatogenic agent, CDRI 84/35.

B. S. Setty, A. Dwivedi, J. P. Maikhuri, 1999, Contraception.

Biodegradable nanoparticles in the murine vagina: trans-cervical retrograde transport and induction of proinflammatory cytokines.

Ritu Malik, A. Misra, J. P. Maikhuri, 2011, Journal of biomedical nanotechnology.

A precisely substituted benzopyran targets androgen refractory prostate cancer cells through selective modulation of estrogen receptors.

Ashish Jain, Vishal Singh, V. Verma, 2015, Toxicology and applied pharmacology.

Novel alkylphospholipid-DTC hybrids as promising agents against endocrine related cancers acting via modulation of Akt-pathway.

R. Konwar, Hamidullah, N. Lal, 2014, European journal of medicinal chemistry.

Effect of antispermatogenic compound CDRI-84/35 on marker enzymes of rat testis cells. A study on site of action.

A. Dwivedi, J. P. Maikhuri, G. Gupta, 1997, Contraception.

Quantitative analysis of spermatogenesis in rats made azoospermic with compound CDRI 84/35

A. Dwivedi, J. P. Maikhuri, S. R. Chowdhury, 1998 .

K. Arya, Vishal Singh, M. F. Khan, 2014, Phytotherapy research : PTR.