G. Gupta

发表

N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition.

Mala Singh, P. Shukla, Shagun Krishna, 2015, European journal of medicinal chemistry.

Increased DNA methylation in the spermatogenesis‐associated (SPATA) genes correlates with infertility

Kiran Singh, S. Mohanty, S. Trivedi, 2019, Andrology.

Sexually Transmitted Infections and Male Infertility: Old Enigma, New Insights

B. Kushwaha, G. Gupta, 2017 .

Innovative Disulfide Esters of Dithiocarbamic Acid as Women‐Controlled Contraceptive Microbicides: A Bioisosterism Approach

S. Sankhwar, P. Shukla, Nidhi Singh, 2015, ChemMedChem.

Inflammation driven tumor‐like signaling in prostatic epithelial cells by sexually transmitted Trichomonas vaginalis

B. Kushwaha, J. P. Maikhuri, G. Gupta, 2020, International journal of urology : official journal of the Japanese Urological Association.

Labda‐8(17),12,14‐trien‐19‐oic Acid Contained in Fruits of Cupressus sempervirens Suppresses Benign Prostatic Hyperplasia in Rat and In Vitro Human Models Through Inhibition of Androgen and STAT‐3 Signaling

K. Arya, Vishal Singh, M. F. Khan, 2014, Phytotherapy research : PTR.

Designed modulation of sex steroid signaling inhibits telomerase activity and proliferation of human prostate cancer cells.

Atul Kumar, A. Dwivedi, Siddhartha Sharma, 2014, Toxicology and applied pharmacology.

Novel metronidazole-chalcone conjugates with potential to counter drug resistance in Trichomonas vaginalis.

D. Rawat, U. C. Rajesh, B. Kushwaha, 2014, European journal of medicinal chemistry.

Changes in uterine ornithine decarboxylase activity and steroid receptor levels during decidualization in the rat induced by CDRI-85/287.

A. Dwivedi, G. Gupta, J. D. Dhar, 1999, European journal of endocrinology.

Gr/gr deletions on Y-chromosome correlate with male infertility: an original study, meta-analyses, and trial sequential analyses

R. Dada, Kiran Singh, S. Sankhwar, 2016, Scientific Reports.

Y chromosome b2/b3 deletions and male infertility: A comprehensive meta-analysis, trial sequential analysis and systematic review.

G. Gupta, S. Rajender, S. K. Bansal, 2016, Mutation research. Reviews in mutation research.

Array-based DNA methylation profiling reveals peripheral blood differential methylation in male infertility.

R. Pandey, Kiran Singh, S. Trivedi, 2019, Fertility and sterility.

Azoospermic infertility is associated with altered expression of DNA repair genes.

N. Agrawal, Kanhaiya Kumar Singh, Kiran Singh, 2019, DNA repair.

Selective estrogen receptor modulators regulate stromal proliferation in human benign prostatic hyperplasia by multiple beneficial mechanisms—action of two new agents

Rajeev Kumar, Ashish Jain, V. Verma, 2012, Investigational New Drugs.

2-Methyl-4/5-nitroimidazole derivatives potentiated against sexually transmitted Trichomonas: Design, synthesis, biology and 3D-QSAR study.

Nidhi Singh, M. Siddiqi, Sonal Gupta, 2016, European journal of medicinal chemistry.

Sperm Maturation in Epididymis

G. Gupta, 2005 .

Combining a synthetic spermicide with a natural trichomonacide for safe, prophylactic contraception.

L. Kumar, Ashish Jain, Vishal Singh, 2014, Human reproduction.

Design, synthesis and biological profiling of aryl piperazine based scaffolds for the management of androgen sensitive prostatic disorders

Nidhi Singh, S. Yadav, S. Jaiswal, 2016 .

Arylpiperazines for management of benign prostatic hyperplasia: design, synthesis, quantitative structure-activity relationships, and pharmacokinetic studies.

Kirti, Y. S. Prabhakar, Ashish Jain, 2011, Journal of medicinal chemistry.

Studies on mechanism(s) of antifertility action of gossypol in rat and hamster.

B. S. Setty, G. Gupta, A. Srivastava, 1989, Contraception.

Designed Chemical Intervention with Thiols for Prophylactic Contraception

Vikas K. Sharma, Lokesh Kumar, L. Kumar, 2013, PloS one.

Novel Trichomonacidal Spermicides

S. K. Jain, Vishal Singh, N. Lal, 2011, Antimicrobial Agents and Chemotherapy.

Imidazole derivatives as possible microbicides with dual protection.

P. Shukla, Ashish Jain, N. Lal, 2010, European journal of medicinal chemistry.

Synthesis of benzenepropanamine analogues as non-detergent spermicides with antitrichomonas and anticandida activities.

M. Singh, P. Shukla, P. Tiwari, 2006, Bioorganic & medicinal chemistry.

The spermicidal and antitrichomonas activities of SSRI antidepressants.

M. Singh, Vinay V. Kumar, P. Tiwari, 2006, Bioorganic & medicinal chemistry letters.

miRNA Profiling of Major Testicular Germ Cells Identifies Stage-Specific Regulators of Spermatogenesis

S. Sethi, G. Gupta, S. Rajender, 2022, Reproductive Sciences.

Activities and androgenic regulation of kreb cycle enzymes in the epididymis and vas deferens of rhesus monkey.

B. S. Setty, G. Gupta, A. Srivastava, 1994, Endocrine research.

Sensitization of androgen refractory prostate cancer cells to anti-androgens through re-expression of epigenetically repressed androgen receptor – Synergistic action of quercetin and curcumin

L. Kumar, S. Mohanty, J. P. Maikhuri, 2016, Molecular and Cellular Endocrinology.

Seasonal variations in daily sperm production rate of rhesus and bonnet monkeys

B. S. Setty, J. P. Maikhuri, G. Gupta, 2000, Journal of medical primatology.

Design of folic acid conjugated chitosan nano-cur–bioenhancers to attenuate the hormone-refractory metastatic prostate carcinoma by augmenting oral bioavailability

Shweta Sharma, P. Dwivedi, P. Mishra, 2016 .

In search of new chemical entities with spermicidal and anti-HIV activities.

S. Batra, A. Bhaduri, S. Srivastava, 1999, Bioorganic & medicinal chemistry.

Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology.

P. Shukla, Lokesh Kumar, L. Kumar, 2016, European journal of medicinal chemistry.

Ammonium salts of carbamodithioic acid as potent vaginal trichomonacides and fungicides.

P. Shukla, S. Yadav, L. Kumar, 2016, International journal of antimicrobial agents.

Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies.

Shagun Krishna, M. Siddiqi, N. Lal, 2015, Bioorganic & medicinal chemistry letters.

Design and synthesis of substituted morpholin/piperidin-1-yl-carbamodithioates as promising vaginal microbicides with spermicidal potential.

Vikas Kumar, P. Shukla, Sonal Gupta, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents.

Ashish Jain, A. Dwivedi, S. Paliwal, 2012, Bioorganic & medicinal chemistry letters.

Potentiating Metronidazole Scaffold against Resistant Trichomonas: Design, Synthesis, Biology and 3D-QSAR Analysis.

S. Jain, Lokesh Kumar, L. Kumar, 2012, ACS medicinal chemistry letters.

Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception.

Sumit Kumar, P. Shukla, Ashish Jain, 2011, Bioorganic & medicinal chemistry letters.

Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides.

P. Shukla, Ashish Jain, L. Kumar, 2008, European journal of medicinal chemistry.

Design and synthesis of γ-butyrolactone derivatives as potential spermicidal agents.

G. Pandey, L. Kumar, A. Dwivedi, 2014, Bioorganic & medicinal chemistry letters.

Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies.

Vikas Kumar, P. Shukla, L. Kumar, 2013, European journal of medicinal chemistry.

The dynamics of gene expression during and post meiosis sets the sperm agenda

S. Yadav, J. P. Maikhuri, G. Gupta, 2019, Molecular reproduction and development.

Androgenic regulation of glycolytic and HMP pathway in epididymis and vas deferens of rhesus monkey.

B. S. Setty, G. Gupta, A. Srivastava, 1993, Indian journal of experimental biology.

Design and synthesis of coumarin–glyoxal hybrids for spermicidal and antimicrobial actions: a dual approach to contraception

A. Dwivedi, Swati Gupta, S. Sankhwar, 2016 .

Role of energy metabolism in the pregnancy interceptive action of Ferula assafoetida and Melia azedarach extracts in rat.

B. S. Setty, M. Bajpai, V. Lakshmi, 2004, Contraception.

Mechanism of action of some acrylophenones, quinolines and dithiocarbamate as potent, non-detergent spermicidal agents.

B. S. Setty, A. Dwivedi, J. P. Maikhuri, 2003, Contraception.

Activities and androgenic regulation of lysosomal enzymes in the epididymis of rhesus monkey.

B. S. Setty, G. Gupta, 1995, Endocrine research.

Mutations in the prostate specific antigen (PSA/KLK3) correlate with male infertility

K. Thangaraj, S. Sankhwar, G. Gupta, 2017, Scientific Reports.

Genome-wide differential methylation analyses identifies methylation signatures of male infertility

N. Agrawal, R. Pandey, Kiran Singh, 2018, Human reproduction.

Disulfiram and its novel derivative sensitize prostate cancer cells to the growth regulatory mechanisms of the cell by re‐expressing the epigenetically repressed tumor suppressor—estrogen receptor β

S. Yadav, N. Lal, V. Verma, 2016, Molecular carcinogenesis.

Rat testicular germ cell type(s) targeted by anti-spermatogenic agents in vivo and their recovery on withdrawal of treatment--a flow cytometric study.

A. Dwivedi, P. Ojha, G. Gupta, 2008, Animal reproduction science.

Oleanolic-bioenhancer coloaded chitosan modified nanocarriers attenuate breast cancer cells by multimode mechanism and preserve female fertility.

Shweta Sharma, P. Dwivedi, P. Mishra, 2017, International journal of biological macromolecules.

A unique dithiocarbamate chemistry during design & synthesis of novel sperm-immobilizing agents.

P. Shukla, Lokesh Kumar, N. Lal, 2014, Organic and biomolecular chemistry.

Substituted carbamothioic amine-1-carbothioic thioanhydrides as novel trichomonicidal fungicides: Design, synthesis, and biology.

P. Shukla, N. Srivastava, Shagun Krishna, 2018, European journal of medicinal chemistry.

Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents.

P. Srivastava, P. Shukla, A. Dwivedi, 2007, Bioorganic & medicinal chemistry.

Novel disulphide esters of carbothioic acid as potent, non-detergent spermicides with low toxicity to Lactobacillus and HeLa cells in vitro.

A. Dwivedi, V. K. Bajpai, K. Mitra, 2007, Human reproduction.

In vitro testing of rationally designed spermicides for selectively targeting human sperm in vagina to ensure safe contraception.

Ashish Jain, A. Dwivedi, V. K. Bajpai, 2009, Human reproduction.

Discovery of substituted isoxazolecarbaldehydes as potent spermicides, acrosin inhibitors and mild anti-fungal agents.

S. Batra, P. Shukla, V. Singh, 2005, Human reproduction.

Effect of spermicides on Lactobacillus acidophilus in vitro-nonoxynol-9 vs. Sapindus saponins.

P. Ojha, J. P. Maikhuri, G. Gupta, 2003, Contraception.

Androgen-estrogen synergy in the regulation of energy metabolism in epididymis and vas deferens of rhesus monkey.

B. S. Setty, G. Gupta, A. Srivastava, 1991, Endocrine research.

Histone Methylation Regulates Gene Expression in the Round Spermatids to Set the RNA Payloads of Sperm

S. Yadav, G. Gupta, S. Rajender, 2022, Reproductive Sciences.

Synergistic chemoprotective mechanisms of dietary phytoestrogens in a select combination against prostate cancer.

Ashish Jain, Rajeev Kumar, V. Verma, 2011, The Journal of nutritional biochemistry.

Functional attenuation of human sperm by novel, non-surfactant spermicides: precise targeting of membrane physiology without affecting structure.

S. Batra, Rajeev Kumar, Ashish Jain, 2010, Human reproduction.

Substituted acrylophenones and related mannich bases as possible spermicides and inhibitors of HIV envelope glycoprotein-CD4 interaction.

A. Dwivedi, S. Habib, Satyawan Singh, 2002, European journal of medicinal chemistry.

Chemical and medicinal versatility of dithiocarbamates: an overview.

V. Bala, G. Gupta, V. L. Sharma, 2014, Mini reviews in medicinal chemistry.

Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines.

R. Konwar, Hamidullah, Sonal Gupta, 2016, Bioorganic & medicinal chemistry letters.

Microbicidal spermicide or spermicidal microbicide?

G. Gupta, 2005, The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception.

Experimental dapsone administration induces infertility in male Wistar rats: Mechanisms and clinical implications.

Y. Raji, G. Gupta, O. S. Akinsomisoye, 2019, Pathophysiology : the official journal of the International Society for Pathophysiology.

Spermicidal activity of bivittoside D from Bohadschia vitiensis.

M. N. Srivastava, S. Mishra, V. Lakshmi, 2008, Archives of medical research.

Quantitative determination of microbicidal spermicide 'nonoxynol-9' in rabbit plasma and vaginal fluid using LC-ESI-MS/MS: application to pharmacokinetic study.

L. Kumar, R. Bhatta, V. Bala, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Coding and regulatory transcriptome comparisons between fertile and infertile spermatozoa identify RNA signatures of male infertility

G. Gupta, Vertika Singh, S. Rajender, 2022, Andrologia.

SPATA16 promoter hypermethylation and downregulation in male infertility

S. Sankhwar, S. Trivedi, G. Gupta, 2022, Andrologia.

The thermo-sensitive gene expression signatures of spermatogenesis

S. Yadav, L. Kumar, B. Kushwaha, 2018, Reproductive Biology and Endocrinology.

SNPs in ERCC1, ERCC2, and XRCC1 genes of the DNA repair pathway and risk of male infertility in the Asian populations: association study, meta-analysis, and trial sequential analysis

Neelabh, K. Thangaraj, Kiran Singh, 2018, Journal of Assisted Reproduction and Genetics.

Changes in carbohydrate metabolism of testicular germ cells during meiosis in the rat.

B. S. Setty, M. Bajpai, G. Gupta, 1998, European journal of endocrinology.

Lipid metabolising enzymes in isolated rat testicular germ cells and changes associated with meiosis

M. Bajpai, S. K. Jain, G. Gupta, 1998, Andrologia.

Energy Utilization for Survival and Fertilization—Parsimonious Quiescent Sperm Turn Extravagant on Motility Activation in Rat1

S. Yadav, L. Kumar, V. Verma, 2016, Biology of reproduction.

Apigenin manipulates the ubiquitin–proteasome system to rescue estrogen receptor-β from degradation and induce apoptosis in prostate cancer cells

S. Yadav, Vishal Singh, V. Verma, 2015, European Journal of Nutrition.

Polymorphisms in the XPC gene affect urinary bladder cancer risk: a case-control study, meta-analyses and trial sequential analyses

S. Sankhwar, G. Gupta, S. Rajender, 2016, Scientific Reports.

Effect of antiandrogens on some key enzymes of glycolysis in epididymis and ventral prostate of rat.

B. S. Setty, G. Gupta, A. Srivastava, 1989, Indian journal of experimental biology.

Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression.

Nidhi Singh, S. Yadav, M. Siddiqi, 2017, European journal of medicinal chemistry.

Effect of antispermatogenic agents on cell marker enzymes of rat Sertoli cells in vitro.

A. Dwivedi, P. Ojha, G. Gupta, 2006, Contraception.

Changes in daily sperm production rate in rats under the influence of a potent antispermatogenic agent, CDRI 84/35.

B. S. Setty, A. Dwivedi, J. P. Maikhuri, 1999, Contraception.

Spermicidal activity of marine sponge Xestospongia officinalis var. Ceylonensis Dendy Full Paper

V. Lakshmi, G. Gupta, 2015 .

Coenzyme Q10 effect on semen parameters: Profound or meagre?

A. Alahmar, G. Gupta, S. Rajender, 2020, Andrologia.

A precisely substituted benzopyran targets androgen refractory prostate cancer cells through selective modulation of estrogen receptors.

Ashish Jain, Vishal Singh, V. Verma, 2015, Toxicology and applied pharmacology.

Novel alkylphospholipid-DTC hybrids as promising agents against endocrine related cancers acting via modulation of Akt-pathway.

R. Konwar, Hamidullah, N. Lal, 2014, European journal of medicinal chemistry.

Effect of antispermatogenic compound CDRI-84/35 on marker enzymes of rat testis cells. A study on site of action.

A. Dwivedi, J. P. Maikhuri, G. Gupta, 1997, Contraception.

K. Arya, Vishal Singh, M. F. Khan, 2014, Phytotherapy research : PTR.

SNPs in ERCC1, ERCC2, and XRCC1 genes of the DNA repair pathway and risk of male infertility in the Asian populations: association study, meta-analysis, and trial sequential analysis

Neelabh, K. Thangaraj, Kiran Singh, 2018, Journal of Assisted Reproduction and Genetics.