I. Mullaney

发表

The potential of metabolomic analysis techniques for the characterisation of α1-adrenergic receptors in cultured N1E-115 mouse neuroblastoma cells

P. Drummond, G. Maker, L. F. Dawson, 2016, Cytotechnology.

Regulation of Spontaneous Activity of the δ‐Opioid Receptor: Studies of Inverse Agonism in Intact Cells

G. Milligan, Z. Georgoussi, I. Mullaney, 1997, Journal of neurochemistry.

Immunological identification of the α subunit of G13, a novel guanine nucleotide binding protein

G. Milligan, I. Mullaney, F. Mitchell, 1992 .

Selective interactions of mu-opioid receptors with pertussis toxin-sensitive G proteins: involvement of the third intracellular loop and the c-terminal tail in coupling.

G. Milligan, C. Zioudrou, Z. Georgoussi, 1997, Biochimica et biophysica acta.

The Roles of Guanine Nucleotide Binding Proteins in Health and Disease

A. Ibegbu, I. Mullaney, L. Fyfe, 2011 .

Combined DNA, toxicological and heavy metal analyses provides an auditing toolkit to improve pharmacovigilance of traditional Chinese medicine (TCM)

Dáithí C. Murray, M. Bunce, M. Bellgard, 2015, Scientific Reports.

Repetitive low intensity magnetic field stimulation in a neuronal cell line: a metabolomics study

A. Garrett, G. Maker, J. Rodger, 2018, PeerJ.

OXIDATIVE STRESS -INDUCED EFFECTS ON PATTERN AND PATTERN FORMATION IN CORTICAL B50 NEURONAL CELLS IN CULTURE

A. Ibegbu, I. Mullaney, L. Fyfe, 2013 .

Oxidative Stress Does Not Predispose Neuronal Cells to Changes in G Protein Coupled (Opioid) Receptor Gene Expression in Cortical B50 Neurons in Culture

A. Ibegbu, I. Mullaney, L. Fyfe, 2012 .

The effects of hypoxia and opioid receptor agonists treatment in cortical B50 neuronal cells in culture

A. Ibegbu, I. Mullaney, L. Fyfe, 2012 .

Regulation of cellular Gsα levels and basal adenylyl cyclase activity by expression of the β2-adrenoceptor in neuroblastoma cell lines

G. Milligan, Gun-Do Kim, I. Mullaney, 1995, Molecular and Cellular Biochemistry.

Overexpression of Gsα in NG108‐15, neuroblastoma X glioma cells: effects on receptor regulation of the stimulatory adenylyl cyclase cascade

G. Milligan, I. Mullaney, I. Craig Carr, 1996 .

Guanine nucleotide binding proteins in neuroblastoma x glioma hybrid, NG108-15, cells. Regulation of expression and function.

G. Milligan, S. McClue, F. McKenzie, 1990, The International journal of biochemistry.

Elevated levels of the guanine nucleotide binding protein, Go, are associated with differentiation of neuroblastoma × glioma hybrid cells

G. Milligan, I. Mullaney, Ian Mullaney, 1989, FEBS letters.

The effect of hypoxia on G protein coupled (CB1) receptor gene expression in cortical B50 neurons in culture

I. Mullaney, L. Fyfe, D. Macbean, 2011 .

Regional modulation of cyclic nucleotides by endothelin‐1 in rat pulmonary arteries: direct activation of Gi2‐protein in the main pulmonary artery

M. Maclean, I. Mullaney, D. Vaughan, 2000, British journal of pharmacology.

Journal Pre-proof and DNA sequencing detects contamination and in regulated medicines and for diet,

I. Musgrave, R. Trengove, M. Coghlan, 2019 .

Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit of the G-protein Gq.

G. Milligan, N. Buckley, I. Mullaney, 1993, The Biochemical journal.

Morphological changes induced by opioid receptor agonist treatment of B50 neuronal cells cultured in hypoxia

A. Ibegbu, I. Mullaney, L. Fyfe, 2013 .

Analysis of inverse agonism at the delta opioid receptor after expression in Rat 1 fibroblasts.

G. Milligan, I. Mullaney, I. C. Carr, 1996, The Biochemical journal.

Agonist-dependent, cholera toxin-catalyzed ADP-ribosylation of pertussis toxin-sensitive G-proteins following transfection of the human alpha 2-C10 adrenergic receptor into rat 1 fibroblasts. Evidence for the direct interaction of a single receptor with two pertussis toxin-sensitive G-proteins, Gi2

G. Milligan, G. Gould, C. Carr, 1991, The Journal of biological chemistry.

Activation, cellular redistribution and enhanced degradation of the G proteins Gq and G11 by endogenously expressed and transfected phospholipase C-coupled muscarinic m1 acetylcholine receptors.

G. Milligan, P. Svoboda, M. Caulfield, 1996, Progress in brain research.

Endothelin-1 modulation of cAMP in rat pulmonary arteries: effect of chronic hypoxia.

I. Mullaney, D. Vaughan, M. Maclean, 1998, Journal of cardiovascular pharmacology.

Endothelial Function In Mesenteric Resistance Arteries From The Genetically Hypertensive Rat

Hanzhong Liu, J. Ledingham, R. Laverty, 2002, Clinical and experimental pharmacology & physiology.

Kainate receptor agonists and antagonists mediate tolerance to kainic acid and reduce high‐affinity GTPase activity in young, but not aged, rat hippocampus

D. Kerr, Blair R Hesp, I. Mullaney, 2004, Journal of neurochemistry.

GTP analogues cause release of the alpha subunit of the GTP binding protein, GO, from the plasma membrane of NG108-15 cells.

G. Milligan, A. Magee, C. Unson, 1988, Biochemical and biophysical research communications.

GTP-binding proteins in brain and neutrophil are tethered to the plasma membrane via their amino termini.

G. Milligan, P. Gierschik, A. Spiegel, 1987, Biochemical and biophysical research communications.

Specificity of interactions of receptors and effectors with GTP-binding proteins in native membranes.

G. Milligan, F. McKenzie, I. Mullaney, 1990, Biochemical Society symposium.

Agonist-mediated tyrosine phosphorylation of isoforms of the shc adapter protein by the delta opioid receptor.

G. Milligan, N. Anderson, I. Mullaney, 1997, Cellular signalling.

Cyclic AMP production in rat mammary gland: influence of β-adrenergic agents on acini in vitro

R. Clegg, I. Mullaney, 1985 .

Acute change in the cyclic AMP content of rat mammary acini in vitro. Influence of physiological and pharmacological agents.

R. Clegg, I. Mullaney, 1985, The Biochemical journal.

Distribution and relative levels of expression of the phosphoinositidase-C-linked G-proteins Gqα and G11α: Absence of G11α in human platelets and haemopoietically derived cell lines

G. Milligan, I. Mullaney, J. F. McCALLUM, 1993 .

Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture

H P Rang, H. Rang, P M Dunn, 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

The roles of G-protein coupled receptors in health and disease conditions

A. Ibegbu, I. Mullaney, L. Fyfe, 2012 .

Untargeted Metabolomic Analysis of Rat Neuroblastoma Cells as a Model System to Study the Biochemical Effects of the Acute Administration of Methamphetamine

R. Trengove, G. Maker, I. Mullaney, 2018, Metabolites.

The application of metabolomics for herbal medicine pharmacovigilance: a case study on ginseng.

M. Bunce, R. Trengove, G. Maker, 2016, Essays in biochemistry.

Drugs affecting blood

I. Mullaney, 2012 .

Quantitative assay of urinary hepcidin using MALDI-TOF mass spectrometry.

J. Olynyk, R. Trengove, D. Trinder, 2010 .

The human muscarinic M1 acetylcholine receptor, when expressed in CHO cells, activates and downregulates both Gqα and G11α equally and non‐selectively

G. Milligan, N. Buckley, I. Mullaney, 1993 .

Antibodies to the GTP binding protein, Go, antagonize noradrenaline-induced calcium current inhibition in NG108-15 hybrid cells

D. A. Brown, G. Milligan, I. McFadzean, 1989, Neuron.

Therapeutic Potentials and uses of Cannabinoid Agonists in Health and Disease Conditions

A. Ibegbu, I. Mullaney, L. Fyfe, 2012 .

Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat.

P. Sheard, A. Zimmermann, P. Hessian, 2004, Journal of hepatology.

Identification of Two Distinct Isoforms of the Guanine Nucleotide Binding Protein Go in Neuroblastoma × Glioma Hybrid Cells: Independent Regulation During Cyclic AMP‐Induced Differentiation

G. Milligan, I. Mullaney, 1990, Journal of neurochemistry.

Differential regulation of amounts of the guanine-nucleotide-binding proteins Gi and Go in neuroblastoma x glioma hybrid cells in response to dibutyryl cyclic AMP.

G. Milligan, A. Magee, C. Unson, 1988, The Biochemical journal.

The Roles of Opioid Receptors and Agonists in Health and Disease Conditions

A. Ibegbu, I. Mullaney, L. Fyfe, 2011 .

Expression of Two Isoforms of the Guanine Nucleotide Binding Protein,G o , IN NG108–15 Neuroglioma Cells

G. Milligan, I. Mullaney, 1991 .

Biochemical approaches to examine the specificity of interactions between receptors and guanine nuclotide binding proteins.

B. H. Shah, G. Milligan, I. Mullaney, 1995, Journal of receptor and signal transduction research.

Inverse agonism at adrenergic and opioid receptors: studies with wild type and constitutively active mutant receptors.

G. Milligan, D. MacEwan, I. Mullaney, 1997, Receptors & channels.

Agonist activation of p42 and p44 mitogen-activated protein kinases following expression of the mouse delta opioid receptor in Rat-1 fibroblasts: effects of receptor expression levels and comparisons with G-protein activation.

G. Milligan, N. Anderson, I. Mullaney, 1996, The Biochemical journal.

Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.

G. Milligan, F. McKenzie, I. Mullaney, 1992, The Biochemical journal.

Equivalent regulation of wild type and an epitope‐tagged variant of Gsα by the IP prostanoid receptor following expression in neuroblastoma × glioma hybrid, NG108‐15, cells

G. Milligan, I. Mullaney, 1994, FEBS Letters.

Regulation of the stoichiometry of protein components of the stimulatory adenylyl cyclase cascade.

G. Milligan, D. MacEwan, I. Mullaney, 1998, Advances in pharmacology.

Experimental design and reporting standards for metabolomics studies of mammalian cell lines

R. Trengove, G. Maker, Sarah R. Hayton, 2017, Cellular and Molecular Life Sciences.

Activation of Guanylate Cyclase by Bradykinin in Rat Sensory Neurones Is Mediated by Calcium Influx: Possible Role of the Increase in Cyclic GMP

J. Wood, G. Burgess, M. McNeill, 1989, Journal of neurochemistry.

Untargeted metabolomics of neuronal cell culture: A model system for the toxicity testing of insecticide chemical exposure

R. Trengove, G. Maker, Sarah R. Hayton, 2017, Journal of applied toxicology : JAT.

Capsaicin‐Induced Ion Fluxes Increase Cyclic GMP but Not Cyclic AMP Levels in Rat Sensory Neurones in Culture

G. Burgess, M. McNeill, I. Mullaney, 1989, Journal of neurochemistry.

Widespread distribution of Gq alpha/G11 alpha detected immunologically by an antipeptide antiserum directed against the predicted C-terminal decapeptide.

G. Milligan, S. Arkinstall, M. Wakelam, 1991, FEBS letters.

GTP analogues promote release of the alpha subunit of the guanine nucleotide binding protein, Gi2, from membranes of rat glioma C6 BU1 cells.

G. Milligan, L. Marshall, A. Spiegel, 1988, The Biochemical journal.

Identification and Quantitation of G Protein α-Subunits

G. Milligan, I. Mullaney, 1997 .

Expression of the Human β2‐Adrenoceptor in NCB20 Cells Results in Agonist Activation of Adenylyl Cyclase and Agonist‐Mediated Selective Down‐Regulation of Gsα

B. H. Shah, G. Milligan, A. Wise, 1995 .

Br. J. Pharmacol. Toxicol

A. Ibegbu, I. Mullaney, L. Fyfe, 2011 .

Role of Hepatic Stellate Cells in the Early Phase of Liver Regeneration in Rat: Formation of Tight Adhesion to Parenchymal Cells

P. Sheard, A. Zimmermann, P. Hessian, 2004, Comparative hepatology.