D. Souza

发表

CCR1 Plays a Critical Role in Modulating Pain through Hematopoietic and Non-Hematopoietic Cells

C. Grimaldi, M. Brown, R. Fryer, 2014, PloS one.

The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function.

R. Wasti, S. Lukas, G. W. Peet, 2013, American journal of clinical and experimental immunology.

BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells

J. Swantek, A. Schnapp, D. White, 2016, The Journal of Pharmacology and Experimental Therapeutics.

OP0160 Gut-derived tnf as risk factor for the development of sacroiliac inflammation

M. Brown, D. Elewaut, A. Klimowicz, 2017 .

Discovery of a Series of Pyrazinone RORγ Antagonists and Identification of the Clinical Candidate BI 730357.

S. Brunette, R. Fryer, R. Sibley, 2021, ACS medicinal chemistry letters.

Optimization of drug-like properties of nonsteroidal glucocorticoid mimetics and identification of a clinical candidate.

U. Patel, Yancey D. Ward, Alison J Kukulka, 2014, ACS medicinal chemistry letters.

Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.

M. Emmanuel, Alison J Kukulka, G. Nabozny, 2014, Journal of medicinal chemistry.

Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores.

T. Gilmore, J. Regan, C. Torcellini, 2011, Bioorganic & medicinal chemistry letters.

Nonsteroidal dissociated glucocorticoid agonists containing azaindoles as steroid A-ring mimetics.

T. Gilmore, C. Torcellini, Alison J Kukulka, 2010, Journal of medicinal chemistry.

Identification of novel azaindazole CCR1 antagonist clinical candidates.

Qiang Zhang, M. Brown, D. Skow, 2019, Bioorganic & medicinal chemistry letters.

NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes

S. Chanda, M. Mbow, A. Gounder, 2022, Frontiers in Immunology.

BTK inhibition ameliorates kidney disease in spontaneous lupus nephritis.

C. Putterman, L. Herlitz, G. Nabozny, 2018, Clinical immunology.

Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease

M. Mbow, J. Garnett, Jun Li, 2021, EBioMedicine.

A GPBAR1 (TGR5) Small Molecule Agonist Shows Specific Inhibitory Effects on Myeloid Cell Activation In Vitro and Reduces Experimental Autoimmune Encephalitis (EAE) In Vivo

S. Kauschke, E. Hickey, Andre Broermann, 2014, PloS one.

Kcnn4 Is a Regulator of Macrophage Multinucleation in Bone Homeostasis and Inflammatory Disease

Jun Li, Enrico Petretto, Prashant K. Srivastava, 2014, Cell reports.

Indole Inhibitors of MMP-13 for Arthritic Disorders

Qiang Zhang, I. Muegge, J. Proudfoot, 2021, ACS omega.

The role of leukocyte function-associated antigen-1 in animal models of inflammation.

P. Reilly, G. Nabozny, M. Panzenbeck, 2001, European journal of pharmacology.

Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore.

J. Proudfoot, C. Torcellini, Alison J Kukulka, 2014, Bioorganic & medicinal chemistry letters.

Function-regulating pharmacophores in a sulfonamide class of glucocorticoid receptor agonists.

Alison J Kukulka, G. Nabozny, D. Kuzmich, 2013, Bioorganic & medicinal chemistry letters.