M. Reddehase

M. Reddehase, J. Podlech, N. K. Grzimek, 2002, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Exogenous introduction of an immunodominant peptide from the non-structural IE1 protein of human cytomegalovirus into the MHC class I presentation pathway by recombinant dense bodies.

U. Wolfrum, K. Besold, B. Plachter, 2008, The Journal of general virology.

Cellular and molecular basis of the protective immune response to cytomegalovirus infection.

U. Koszinowski, M. Reddehase, M. D. Val, 1990, Current topics in microbiology and immunology.

CD8 T Cells Control Cytomegalovirus Latency by Epitope-Specific Sensing of Transcriptional Reactivation

D. Strand, Hanna-Mari Tervo, M. Reddehase, 2006, Journal of Virology.

Review article Mouse models of cytomegalovirus latency: overview

M. Reddehase, 2002 .

Focal Transcriptional Activity of Murine Cytomegalovirus during Latency in the Lungs

S. Kurz, M. Reddehase, H. Steffens, 1999, Journal of Virology.

The conditions of primary infection define the load of latent viral genome in organs and the risk of recurrent cytomegalovirus disease

S. Jonjić, U. Koszinowski, M. Balthesen, 1994, The Journal of experimental medicine.

Pathogenesis of classical swine fever: B-lymphocyte deficiency caused by hog cholera virus

A. Saalmüller, M. Šuša, H. Thiel, 1992, Journal of virology.

IL-33/ST2 pathway drives regulatory T cell dependent suppression of liver damage upon cytomegalovirus infection

S. Jonjić, A. Krmpotić, L. Čičin-Šain, 2017, PLoS pathogens.

Pediatric roots of cytomegalovirus recurrence and memory inflation in the elderly

M. Reddehase, S. Adler, 2019, Medical Microbiology and Immunology.

Pediatric roots of cytomegalovirus recurrence and memory inflation in the elderly

M. Reddehase, S. Adler, 2019, Medical Microbiology and Immunology.

Recent advances in CMV tropism, latency, and diagnosis during aging

F. Goodrum, S. Leng, J. Kamil, 2017, GeroScience.

Monoclonal antibodies reactive with swine lymphocytes. II. Detection of an antigen on resting T cells down-regulated after activation.

S. Jonjić, U. Koszinowski, A. Saalmüller, 1987, Journal of immunology.

Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity.

Gunther Hartmann, Linda Diehl, Andreas Limmer, 2010, Gastroenterology.

The cytolytic T lymphocyte response to the murine cytomegalovirus. II. Detection of virus replication stage‐specific antigens by separate populations of in vivo active cytolytic T lymphocyte precursors

U. Koszinowski, G. Keil, M. Reddehase, 1984, European journal of immunology.

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein

U. Koszinowski, H. Schlicht, T. Ruppert, 1991, Cell.

Mouse Model of Cytomegalovirus Disease and Immunotherapy in the Immunocompromised Host: Predictions for Medical Translation that Survived the “Test of Time”

M. Reddehase, N. Lemmermann, 2018, Viruses.

Refining human T-cell immunotherapy of cytomegalovirus disease: a mouse model with ‘humanized’ antigen presentation as a new preclinical study tool

M. Reddehase, N. Lemmermann, 2016, Medical Microbiology and Immunology.

Single cell detection of latent cytomegalovirus reactivation in host tissue.

S. Halle, R. Förster, M. Messerle, 2011, The Journal of general virology.

Transactivation of Cellular Genes Involved in Nucleotide Metabolism by the Regulatory IE1 Protein of Murine Cytomegalovirus Is Not Critical for Viral Replicative Fitness in Quiescent Cells and Host Tissues

D. Strand, Vanessa Wilhelmi, M. Reddehase, 2008, Journal of Virology.

Failure in generating hemopoietic stem cells is the primary cause of death from cytomegalovirus disease in the immunocompromised host

U. Koszinowski, H. Bühring, M. Reddehase, 1988, The Journal of experimental medicine.

Recent advances in CMV tropism, latency, and diagnosis during aging

F. Goodrum, S. Leng, J. Kamil, 2017, GeroScience.

Immune Surveillance of Cytomegalovirus Latency and Reactivation in Murine Models

A. Angulo, M. Messerle, M. Hummel, 2012 .

Liver Sinusoidal Endothelial Cells Are a Site of Murine Cytomegalovirus Latency and Reactivation

P. Deegen, Hanna-Mari Tervo, M. Reddehase, 2009, Journal of Virology.

Cellular reservoirs of latent cytomegaloviruses

M. Reddehase, N. Lemmermann, 2019, Medical Microbiology and Immunology.

Role of antibodies in confining cytomegalovirus after reactivation from latency: three decades’ résumé

S. Jonjić, W. Britt, A. Krmpotić, 2019, Medical Microbiology and Immunology.

Structure of the gene of tum− transplantation antigen P91A: The mutated exon encodes a peptide recognized with Ld by cytolytic T cells

T. Boon, C. Lurquin, E. Plaen, 1989, Cell.

Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors

K. Freitag, M. Reddehase, N. Lemmermann, 2020, Vaccines.

Expression of subregion and haplotype preference for H-2Kk restricted cytotoxic t-cell responses in vivi and at the level of the precursor frequencies.

W. Dröge, M. Wolf, M. Reddehase, 1981, Cellular immunology.

Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase

U. Koszinowski, Ulrich H. Koszinowski, Margarita Del Val, 1989, Cell.

Reverse Genetics Modification of Cytomegalovirus Antigenicity and Immunogenicity by CD8 T-Cell Epitope Deletion and Insertion

Kai A. Kropp, M. Reddehase, N. Lemmermann, 2010, Journal of biomedicine & biotechnology.

Immune Evasion Proteins of Murine Cytomegalovirus Preferentially Affect Cell Surface Display of Recently Generated Peptide Presentation Complexes

P. Deegen, M. Reddehase, N. Lemmermann, 2009, Journal of Virology.

Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein

D Rognan, G Folkers, D. Rognan, 1992, Proteins.

The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription

S. Jonjić, Markus Stempel, Melanie M. Brinkmann, 2017, PLoS pathogens.

Cytomegalovirus-Associated Inhibition of Hematopoiesis Is Preventable by Cytoimmunotherapy With Antiviral CD8 T Cells

M. Reddehase, N. Lemmermann, J. Podlech, 2020, Frontiers in Cellular and Infection Microbiology.

Frequency analysis of cytolytic T lymphocyte precursors (CTL‐P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL‐P

U. Koszinowski, M. Reddehase, J. Cox, 1984, European journal of immunology.

Two Antigenic Peptides from Genes m123 and m164 of Murine Cytomegalovirus Quantitatively Dominate CD8 T-Cell Memory in the H-2d Haplotype

M. Reddehase, J. Podlech, R. Holtappels, 2002, Journal of Virology.

Non-cognate bystander cytolysis by clonal epitope-specific CTL lines through CD28-CD80 interaction inhibits antibody production: A potential caveat to CD8 T-cell immunotherapy.

E. Schmitt, M. Reddehase, N. Lemmermann, 2016, Cellular immunology.

Impairment of TGF-beta signaling in T cells increases susceptibility to experimental autoimmune hepatitis in mice.

P. Schirmacher, P. Galle, M. Blessing, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Evidence against a key role for transforming growth factor-beta1 in cytomegalovirus-induced bone marrow aplasia.

M. Reddehase, J. Podlech, H. Steffens, 1998, The Journal of general virology.

Generation of cytotoxic T lymphocytes against TNP-haptenated syngeneic cells in microcultures: the effect of nude spleen cells as accessory cells.

M. Wolf, M. Reddehase, W. Droege, 1981, Cellular immunology.

Noncanonical Expression of a Murine Cytomegalovirus Early Protein CD8 T-Cell Epitope as an Immediate Early Epitope Based on Transcription from an Upstream Gene

M. Reddehase, N. Lemmermann, R. Holtappels, 2014, Viruses.

A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum.

S. Tenzer, Judith M. Müller, D. Strand, 2010, The Journal of general virology.

Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice

B. Plachter, P. Hoffmann, M. Theobald, 2015, PLoS pathogens.

Quantitative Analysis of Activated Cytolytic T Lymphocytes Present in Vivo After Infection with the Murine Cytomegalovirus

U. Koszinowski, G. Keil, M. Reddehase, 1984 .

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection

U. Koszinowski, M. Reddehase, 1984, Nature.

Interleukin 2 is not sufficient as helper component for the activation of cytotoxic T lymphocytes but synergizes with a late helper effect that is provided by irradiated I-region-incompatible stimulator cells.

W. Falk, M. Reddehase, W. Droege, 1982, Journal of immunology.

Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection

Steffi Krauter, B. Plachter, K. Freitag, 2021, Frontiers in Immunology.

Immunodominant Cytomegalovirus Epitopes Suppress Subdominant Epitopes in the Generation of High-Avidity CD8 T Cells

K. Freitag, M. Reddehase, R. Holtappels, 2021, Pathogens.

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors

Jennifer D. Oduro, P. Klenerman, A. Riemer, 2016, PLoS pathogens.

Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance

M. Reddehase, N. Lemmermann, J. Podlech, 2016, Front. Immunol..

Identification of an atypical CD8 T cell epitope encoded by murine cytomegalovirus ORF-M54 gaining dominance after deletion of the immunodominant antiviral CD8 T cell specificities

M. Reddehase, N. Lemmermann, R. Holtappels, 2015, Medical Microbiology and Immunology.

Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection

K. Freitag, M. Reddehase, J. Podlech, 2012, Medical Microbiology and Immunology.

Subdominant CD8 T-Cell Epitopes Account for Protection against Cytomegalovirus Independent of Immunodomination

M. Munks, P. Deegen, A. Hill, 2008, Journal of Virology.

Immune Evasion Proteins Enhance Cytomegalovirus Latency in the Lungs

M. Reddehase, R. Holtappels, C. Simon, 2009, Journal of Virology.

Processing and Presentation of Murine Cytomegalovirus pORFm164-Derived Peptide in Fibroblasts in the Face of All Viral Immunosubversive Early Gene Functions

M. Reddehase, R. Holtappels, C. Simon, 2002, Journal of Virology.

The Putative Natural Killer Decoy Early Genem04 (gp34) of Murine Cytomegalovirus Encodes an Antigenic Peptide Recognized by Protective Antiviral CD8 T Cells

G. Geginat, M. Reddehase, J. Podlech, 2000, Journal of Virology.

Preemptive CD8 T-Cell Immunotherapy of Acute Cytomegalovirus Infection Prevents Lethal Disease, Limits the Burden of Latent Viral Genomes, and Reduces the Risk of Virus Recurrence

S. Kurz, M. Reddehase, R. Holtappels, 1998, Journal of Virology.

Cytomegalovirus Disease: Hemopoietic Recovery and Immune Control of Pulmonary Infection After Bone Marrow Transplantation

M. Reddehase, 1996 .

Principles for studying in vivo attenuation of virus mutants: defining the role of the cytomegalovirus gH/gL/gO complex as a paradigm

B. Adler, M. Reddehase, N. Lemmermann, 2015, Medical Microbiology and Immunology.

The immunogenicity of human and murine cytomegaloviruses.

M. Reddehase, 2000, Current opinion in immunology.

Rescue of myeloid lineage-committed preprogenitor cells from cytomegalovirus-infected bone marrow stroma

U. Koszinowski, M. Reddehase, F. Busch, 1991, Journal of virology.

Positive Role of the MHC Class-I Antigen Presentation Regulator m04/gp34 of Murine Cytomegalovirus in Antiviral Protection by CD8 T Cells

Thomas Bukur, M. Reddehase, N. Lemmermann, 2020, Frontiers in Cellular and Infection Microbiology.

Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection

K. Freitag, M. Reddehase, J. Podlech, 2012, Medical Microbiology and Immunology.

Murine cytomegalovirus immune evasion proteins operative in the MHC class I pathway of antigen processing and presentation: state of knowledge, revisions, and questions

Vanessa Wilhelmi, M. Reddehase, N. Lemmermann, 2012, Medical Microbiology and Immunology.

Epitope-specific in vivo protection against cytomegalovirus disease by CD8 T cells in the murine model of preemptive immunotherapy

P. Deegen, M. Reddehase, N. Lemmermann, 2008, Medical Microbiology and Immunology.

Cytomegalovirus Misleads Its Host by Priming of CD8 T Cells Specific for an Epitope Not Presented in Infected Tissues

M. Wagner, M. Reddehase, J. Podlech, 2004, The Journal of experimental medicine.

Principles of cytomegalovirus antigen presentation in vitro and in vivo.

U. Koszinowski, M. Reddehase, M. Del Val, 1992, Seminars in Immunology.

Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus Spread

K. Freitag, M. Reddehase, N. Lemmermann, 2022, Viruses.

The major virus-producing cell type during murine cytomegalovirus infection, the hepatocyte, is not the source of virus dissemination in the host.

U. Koszinowski, Z. Ruzsics, Stefan Jordan, 2008, Cell host & microbe.

Hematopoietic stem cell deficiency resulting from cytomegalovirus infection of bone marrow stroma

P. Angele, M. Šuša, M. Balthesen, 2005, Annals of Hematology.

[Recommendations for the diagnosis and therapy of cytomegalovirus infection after stem-cell transplantation. The Research Alliance on the Complications of Organ Transplantation due to Herpes Viruses].

H. Einsele, C. Schmidt, B. Fleckenstein, 1999, Deutsche medizinische Wochenschrift.

Stalemating a clever opportunist: lessons from murine cytomegalovirus.

M. Reddehase, J. Podlech, R. Holtappels, 2004, Human immunology.

Mast cells: innate attractors recruiting protective CD8 T cells to sites of cytomegalovirus infection

M. Becker, M. Stassen, M. Reddehase, 2015, Medical Microbiology and Immunology.

Adoptive CD8 T cell control of pathogens cannot be improved by combining protective epitope specificities.

G. Geginat, J. Janda, M. Reddehase, 2008, The Journal of infectious diseases.

Early gene m18, a novel player in the immune response to murine cytomegalovirus.

M. Reddehase, R. Holtappels, N. K. Grzimek, 2002, The Journal of general virology.

Identification of a K(d)-restricted antigenic peptide encoded by murine cytomegalovirus early gene M84.

D. Thomas, M. Reddehase, R. Holtappels, 2000, The Journal of general virology.

Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune Evasion

M. Reddehase, N. Lemmermann, J. Podlech, 2022, Viruses.

Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells

M. Reddehase, N. Lemmermann, R. Holtappels, 2012, Medical Microbiology and Immunology.

Identification of a Kd-restricted antigenic peptide encoded by murine cytomegalovirus early gene M 84

M. Reddehase, R. Holtappels, Doris Thomas, 2022 .

Stable expression of clonal specificity in murine cytomegalovirus-specific large granular lymphoblast lines propagated long-term in recombinant interleukin 2.

U. Koszinowski, R. Zawatzky, F. Weiland, 1987, Immunobiology.

Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells

M. Reddehase, N. Lemmermann, R. Holtappels, 2012, Medical Microbiology and Immunology.

Murine cytomegalovirus immune evasion proteins operative in the MHC class I pathway of antigen processing and presentation: state of knowledge, revisions, and questions

Vanessa Wilhelmi, M. Reddehase, N. Lemmermann, 2012, Medical Microbiology and Immunology.

Consequence of Histoincompatibility beyond GvH-Reaction in Cytomegalovirus Disease Associated with Allogeneic Hematopoietic Cell Transplantation: Change of Paradigm

M. Reddehase, N. Lemmermann, R. Holtappels, 2021, Viruses.

TGF-β Regulates Airway Responses Via T Cells 1

P. Galle, M. Blessing, A. Lohse, 2003, The Journal of Immunology.

Immune system of swine: dissection of mononuclear leucocyte subpopulations by means of two-colour cytofluorometric analysis.

A. Saalmüller, M. Reddehase, 1988, Research in veterinary science.

Explorer Ablation of the Regulatory IE 1 Protein of Murine Cytomegalovirus Alters In Vivo Pro-inflammatory TNF-alpha Production during Acute Infection

I. Fraser, P. Ghazal, S. Jonjić, 2017 .

K. Reifenberg, K. Freitag, Vanessa Wilhelmi, 2012, Medical Microbiology and Immmunology.

γ/δT-Lymphocyte Subsets in Swine

A. Saalmüller, M. Reddehase, W. Hirt, 1991 .

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection

M. Reddehase, N. Lemmermann, 2021, Pathogens.

The cytolytic T lymphocyte response to the murine cytomegalovirus. I. Distinct maturation stages of cytolytic T lymphocytes constitute the cellular immune response during acute infection of mice with the murine cytomegalovirus.

U. Koszinowski, G. Keil, M. Reddehase, 1984, Journal of immunology.

Cytomegaloviruses : from molecular pathogenesis to intervention

M. Reddehase, 2013 .

Mechanism of tumor remission by cytomegalovirus in a murine lymphoma model: evidence for involvement of virally induced cellular interleukin-15

M. Reddehase, J. Podlech, Katja C. Erlach, 2015, Medical Microbiology and Immunology.

An endocytic YXXΦ (YRRF) cargo sorting motif in the cytoplasmic tail of murine cytomegalovirus AP2 ‘adapter adapter’ protein m04/gp34 antagonizes virus evasion of natural killer cells

M. Reddehase, N. Lemmermann, S. Ebert, 2015, Medical Microbiology and Immunology.

Immunity to viruses.

M. Reddehase, 1989, Immunology today.

Localization of Viral Epitope-Specific CD8 T Cells during Cytomegalovirus Latency in the Lungs and Recruitment to Lung Parenchyma by Airway Challenge Infection

D. Lukas, M. Reddehase, N. Lemmermann, 2021, Life.

‘Checks and balances’ in cytomegalovirus-host cohabitation

M. Reddehase, 2019, Medical Microbiology and Immmunology.

‘Checks and balances’ in cytomegalovirus-host cohabitation

M. Reddehase, 2019, Medical Microbiology and Immmunology.

Viral latency drives ‘memory inflation’: a unifying hypothesis linking two hallmarks of cytomegalovirus infection

Kai A. Kropp, Marion Griessl, M. Reddehase, 2012, Medical Microbiology and Immunology.

Infection of phagocytic cells.

S. Kaufmann, M. Reddehase, Stefan H. E. Kaufmann, 1989, Current Opinion in Immunology.

Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes

S. Jonjić, F. Weiland, M. Reddehase, 1989, The Journal of experimental medicine.

A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum.

S. Tenzer, Judith M. Müller, D. Strand, 2010, The Journal of general virology.

TLR3-independent activation of mast cells by cytomegalovirus contributes to control of pulmonary infection

M. Reddehase, N. Lemmermann, 2017, Cellular &Molecular Immunology.

Single cell detection of latent cytomegalovirus reactivation in host tissue.

R. Förster, M. Messerle, U. Maus, 2011, The Journal of general virology.

In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection

U. Koszinowski, M. Reddehase, W. Mutter, 1987, The Journal of experimental medicine.

TCR-Ligand koff Rate Correlates with the Protective Capacity of Antigen-Specific CD8+ T Cells for Adoptive Transfer

M. Neuenhahn, D. Busch, S. Riddell, 2013, Science Translational Medicine.

Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency.

K. Freitag, M. Reddehase, J. Podlech, 2011, The Journal of general virology.

Zeitschrift Für Immunitätsforschung Editors Editor-in-chief Gustav Fischer Verlag @bullet Stuttgart @bullet New York @bullet 1993 Tumor-induced Macrophage Tumor Necrosis Factor-oc Production Suppresses Autoreactive T Cell Proliferation 430 Induction of Ige and Iggl in Human B Cell Cultures with Stap

R. Brezinschek, G. Vanham, S. Euvrard, 2011 .

Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response

M. Reddehase, N. Lemmermann, R. Holtappels, 2023, Frontiers in immunology.

Direct Antigen Presentation is the Canonical Pathway of Cytomegalovirus CD8 T-cell Priming Regulated by Balanced Immune Evasion Mounting a Strong Antiviral Response

Melanie M. Brinkmann, M. Reddehase, N. Lemmermann, 2023, bioRxiv.

Latency versus persistence or intermittent recurrences: evidence for a latent state of murine cytomegalovirus in the lungs

M. Reddehase, H. Steffens, S. Kurz, 1997, Journal of virology.

Synergism between the components of the bipartite major immediate-early transcriptional enhancer of murine cytomegalovirus does not accelerate virus replication in cell culture and host tissues.

Kai A. Kropp, M. Reddehase, J. Podlech, 2009, The Journal of general virology.

Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation

K. Freitag, M. Reddehase, N. Lemmermann, 2024, Frontiers in immunology.

Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells

K. Freitag, M. Reddehase, N. Lemmermann, 2023, bioRxiv.

In vivo impact of cytomegalovirus evasion of CD8 T-cell immunity: facts and thoughts based on murine models.

M. Reddehase, N. Lemmermann, R. Holtappels, 2011, Virus research.

Cytomegalovirus Misleads Its Host by Priming of CD8 T Cells Specific for an Epitope Not Presented in Infected Tissues

M. Wagner, M. Reddehase, J. Podlech, 2004, The Journal of experimental medicine.

Margaret Gladys Smith, mother of cytomegalovirus: 60th anniversary of cytomegalovirus isolation

M. Reddehase, 2015, Medical Microbiology and Immunology.

Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells

M. Reddehase, N. Lemmermann, R. Holtappels, 2024, PLoS pathogens.

Frequency analysis of cytolytic T cell precursors (CTL‐P) generated in vivo during lethal rabies infection of mice. I. Distinction of CTL‐P with different interleukin 2 sensitivity

M. Reddehase, J. Cox, Ulrich H. Koszinowski, 1982, European journal of immunology.