David J. Matye

发表

Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice

Tiangang Li, Cheng Chen, Jibiao Li, 2019, Journal of Lipid Research.

Sortilin 1 knockout alters basal adipose glucose metabolism but not diet‐induced obesity in mice

Tiangang Li, Jibiao Li, David J. Matye, 2017, FEBS letters.

Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1*

Tiangang Li, P. Krishnamurthy, Feng Li, 2016, The Journal of Biological Chemistry.

Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes.

Tiangang Li, W. Ding, Yuan Li, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Cullin neddylation inhibitor attenuates hyperglycemia by enhancing hepatic insulin signaling through insulin receptor substrate stabilization

J. Friedman, Tiangang Li, M. N. Hasan, 2022, Proceedings of the National Academy of Sciences.

Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1–AKT–mTOR Axis in Mice

J. Chiang, Tiangang Li, W. Ding, 2016, Cellular and molecular gastroenterology and hepatology.

Insulin Resistance Induces Posttranslational Hepatic Sortilin 1 Degradation in Mice*

Tiangang Li, Jibiao Li, David J. Matye, 2015, The Journal of Biological Chemistry.

HNF4α Regulates CSAD to Couple Hepatic Taurine Production to Bile Acid Synthesis in Mice.

Tiangang Li, Nga T. Nguyen, Yuxia Zhang, 2018, Gene expression.

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Tiangang Li, W. Ding, S. Gunewardena, 2020, Nature Communications.

Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated Mice

H. Jaeschke, Tiangang Li, B. Woolbright, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic Steatohepatitis

Huaiwen Wang, J. Friedman, Tiangang Li, 2021, Cellular and molecular gastroenterology and hepatology.

Effects of apical sodium-bile acid transporter inhibitor and obeticholic acid co-treatment in experimental non-alcoholic steatohepatitis.

Tiangang Li, M. N. Hasan, Xuan Qin, 2022, Liver research.

TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis

Shelly C. Lu, Huaiwen Wang, Yanhong Du, 2022, Nature Communications.

Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury.

Tiangang Li, W. Ding, Katie Dennis, 2018, JCI insight.

Liver-specific microRNA-185 knockout promotes cholesterol dysregulation in mice

Tiangang Li, Cheng Chen, David J. Matye, 2020, Liver research.

Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice

Huaiwen Wang, Yanhong Du, Tiangang Li, 2023, Journal of lipid research.

Gut-restricted apical sodium-dependent bile acid transporter inhibitor attenuates alcohol-induced liver steatosis and injury in mice.

Huaiwen Wang, Tiangang Li, W. Ding, 2021, Alcoholism, clinical and experimental research.

Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury.

Tiangang Li, W. Ding, Katie Dennis, 2018, JCI insight.

Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity.

Yanhong Du, David J. Matye, Lijie Gu, 2024, Biochemical pharmacology.