P. Kourounakis

发表

Effect of a novel NSAID derivative with antioxidant moiety on oxidative damage caused by liver and cerebral ischaemia‐reperfusion in rats

K. Tsiakitzis, K. Kotzampassi, A. Kourounakis, 2002, The Journal of pharmacy and pharmacology.

Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis.

V. Manolopoulos, A. Tavridou, A. Papalois, 2006, European journal of pharmacology.

Liver ultrastructure during acute stress.

P. Kourounakis, B. Tuchweber, M. Salas, 1980, Pathology, research and practice.

Lipid-lowering (hetero)aromatic tetrahydro-1,4-oxazine derivatives with antioxidant and squalene synthase inhibitory activity.

A. Kourounakis, P. Kourounakis, E. Rekka, 2008, Journal of medicinal chemistry.

Novel piperidine derivatives: inhibitory properties towards cytochrome P450 isoforms, and cytoprotective and cytotoxic characteristics.

N. Vermeulen, J. Commandeur, P. Kourounakis, 1996, Environmental toxicology and pharmacology.

Stress and Active Oxygen Species – Effect of α‐Tocopherol on Stress Response

K. Tsiakitzis, A. Kourounakis, P. Kourounakis, 2005 .

Structural features and protective activity of dexamethasone and pregnenolone‐16α‐carbonitrile

T. Theophanides, P. Kourounakis, A. Terzis, 1976 .

Influence of steroids and stress on toxicity and disposition of tetraethylammonium bromide.

H. Selye, P. Kourounakis, 1976, Journal of pharmaceutical sciences.

Influence of adrenocorticotropic hormone, somatotrophic hormone and pregnenolone-16alpha-carbonitrile on drug response and metabolism.

S. Szabó, H. Selye, P. Kourounakis, 1975, Biochemical pharmacology.

Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats.

S. Szabó, H. Selye, P. Kourounakis, 1974, Biochemical pharmacology.

Effect of various steroids and ACTH on distribution of zoxazolamine in rats.

S. Szabó, H. Selye, P. Kourounakis, 1973, Journal of pharmaceutical sciences.

Effect of various steroids and ACTH on plasma levels of zoxazolamine and dicumarol.

S. Szabó, H. Selye, P. Kourounakis, 1973, Journal of pharmaceutical sciences.

Effect of various steroids and ACTH on methyprylon plasma levels and sleeping time in rats

S. Szabó, H. Selye, P. Kourounakis, 1973, The Journal of pharmacy and pharmacology.

Protection against phenylisothiocyanate by various steroids, phenobarbitone and diphenylhydantoin

S. Szabó, H. Selye, P. Kourounakis, 1972, The Journal of pharmacy and pharmacology.

Novel 1,4 Substituted Piperidine Derivatives. Synthesis and Correlation of Antioxidant Activity with Structure and Lipophilicity

V. Demopoulos, P. Kourounakis, E. Rekka, 1995, The Journal of pharmacy and pharmacology.

Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.

P. Kourounakis, E. Rekka, Malamati Kourti, 2015, Bioorganic & medicinal chemistry letters.

Antioxidant Serine-(NSAID) Hybrids with Anti-Inflammatory and Hypolipidemic Potency

P. Kourounakis, E. Rekka, P. Theodosis-Nobelos, 2021, Molecules.

Design, Synthesis and Study of Nitrogen Monoxide Donors as Potent Hypolipidaemic and Anti-Inflammatory Agents

M. Pantelidou, P. Kourounakis, C. Athanasekou, 2019, Molecules.

Novel polyfunctional esters of ibuprofen and ketoprofen with hypolipidemic, lipoxygenase inhibitory and enhanced anti-inflammatory activity

P. Kourounakis, C. Athanasekou, E. Rekka, 2016, Medicinal Chemistry Research.

Antioxidant potential of natural and synthesised polyprenylated hydroquinones.

V. Roussis, L. Tziveleka, C. Vagias, 2002, Bioorganic & medicinal chemistry.

Novel N-substituted 3-aminosteroids which exhibit anti-inflammatory properties and influence free radical processes

V. Demopoulos, P. Kourounakis, E. Rekka, 1993 .

Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias.

P. Papazafiri, A. Detsi, T. Calogeropoulou, 2001, Journal of medicinal chemistry.

An approach to QSAR of 16-substituted pregnenolones as microsomal enzyme inducers

P. Kourounakis, E. Rekka, 2010, European Journal of Drug Metabolism and Pharmacokinetics.

Cu(II) complex of an estradiol derivative with potent anti‐inflammatory properties

V. Demopoulos, P. Kourounakis, E. Rekka, 1991, Archiv der Pharmazie.

Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.

D. Galanakis, A. Kourounakis, P. Kourounakis, 2004, Bioorganic & medicinal chemistry letters.

Reduction of gastrointestinal toxicity of NSAIDs via molecular modifications leading to antioxidant anti-inflammatory drugs.

K. Tsiakitzis, D. Galanakis, A. Kourounakis, 2000, Toxicology.

Synthesis and pharmacological evaluation of novel derivatives of anti‐inflammatory drugs with increased antioxidant and anti‐inflammatory activities

D. Galanakis, A. Kourounakis, P. Kourounakis, 1999 .

Hypocholesterolemic and hypolipidemic activity of some novel morpholine derivatives with antioxidant activity.

P. Kourounakis, E. Rekka, M. Chrysselis, 2000, Journal of medicinal chemistry.

Solid and solution behavior of sulphonylurea complexes with ions of IIA group metals. Molecular modeling of K[Zn(ClCH4SO2NCONHC3H7)3] and action of zinc-sulphonylurea complexes as hypoglycemic agents.

G. Manoussakis, D. Kessissoglou, P. Kourounakis, 1990, Journal of inorganic biochemistry.

Interactions of platinum(II) with adenosine and its acetyl derivatives

T. Theophanides, N. Hadjiliadis, P. Kourounakis, 1973 .

Synthesis and antiinflammatory activity of some new thiazole derivatives.

A. Geronikaki, P. Kourounakis, R. Mgonzo, 1995, Die Pharmazie.

Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile.

P. Eleftheriou, P. Kourounakis, E. Rekka, 2005, Bioorganic & medicinal chemistry.

Mercury and cadmium thiosteroid complexes

T. Theophanides, P. Kourounakis, G. Pouskouleli, 1977 .

Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias.

P. Papazafiri, A. Detsi, T. Calogeropoulou, 2004, Bioorganic & medicinal chemistry.

Medicinal chemistry of 2,2,4-substituted morpholines.

P. Kourounakis, E. Rekka, 2010, Current medicinal chemistry.

A novel antioxidant non-steroidal anti-inflammatory agent protects rat liver against ischemia-reperfusion injury.

D. Hadjipavlou-Litina, V. Gorgoulis, I. Andreadou, 2004, In vivo.

Platinum compounds in cancer chemotherapy.

P. Kourounakis, G. Pouskouleli, 1980, Biochemistry and experimental biology.

Antiatherosclerotic Properties of EP2302, a Novel Squalene Synthase Inhibitor, in the Cholesterol-fed Rabbit

V. Manolopoulos, A. Tavridou, A. Papalois, 2008, Journal of cardiovascular pharmacology.

EP2306 [2-(4-Biphenyl)-4-methyl-octahydro-1,4-benzoxazin-2-ol, hydrobromide], A Novel Squalene Synthase Inhibitor, Reduces Atherosclerosis in the Cholesterol-Fed Rabbit

V. Manolopoulos, A. Tavridou, A. Papalois, 2007, Journal of Pharmacology and Experimental Therapeutics.

Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties.

A. Kourounakis, P. Kourounakis, E. Rekka, 2007, Bioorganic & medicinal chemistry.

New analogues of butylated hydroxytoluene as anti-inflammatory and antioxidant agents.

P. Eleftheriou, P. Kourounakis, E. Rekka, 2006, Bioorganic & medicinal chemistry.

Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties.

K. Tsiakitzis, P. Eleftheriou, D. Galanakis, 2006, Bioorganic & medicinal chemistry letters.

Experimental hyperlipidemia and the effect of NSAIDs.

P. Victoratos, A. Kourounakis, P. Kourounakis, 2002, Experimental and molecular pathology.

Chemistry and Molecular Aspects of Drug Design and Action

P. Kourounakis, E. Rekka, 2008 .

Medicinal Chemistry: Synthesis and Pharmacochemical Investigation of Some Novel 1, 2, 4‐4H‐triazoles with Potential Antiviral Activity

E. Clercq, P. Kourounakis, E. Tani, 1998, The Journal of pharmacy and pharmacology.

Synthesis, physicochemical properties and biological studies of some substituted 2-alkoxy-4-methyl-morpholines☆

P. Kourounakis, E. Rekka, 1989 .

Alkannin and Shikonin: Effect on Free Radical Processes and on Inflammation ‐ A Preliminary Pharmacochemical Investigation

A. Assimopoulou, V. Papageorgiou, A. Gavalas, 2002, Archiv der Pharmazie.

Xenobiotic Metabolising Enzymes: Impact on Pathologic Conditions, Drug Interactions and Drug Design.

M. Pantelidou, P. Kourounakis, E. Rekka, 2019, Current topics in medicinal chemistry.

Effect of phenobarbital or pregnenolone-16alpha-carbonitrile (PCN) pretreatment on acute carbon tetrachloride hepatotoxicity in rats.

P. Kourounakis, B. Tuchweber, J. Werringloer, 1974, Biochemical pharmacology.

Effect of fluorosteroids on drug response and metabolism.

S. Szabó, H. Selye, P. Kourounakis, 1976, Biochemical pharmacology.

Estrogen-cis-dichloroethylenediamineplatinum (II) complexes: synthesis and evaluation of binding affinity for estrogen receptors and the effect on breast cancer MCF-7 cells

D. Kouretas, V. Demopoulos, A. Kortsaris, 1992 .

Synthesis and activity on free radical processes and inflammation of 9,10-dihydro-5,8-dimethoxy-triptycene-quinones.

A. Kourounakis, P. Kourounakis, S. Spyroudis, 2003, European journal of medicinal chemistry.

Protective effect of a novel antioxidant non-steroidal anti-inflammatory agent (compound IA) on intestinal viability after acute mesenteric ischemia and reperfusion.

I. Andreadou, M. Sechas, A. Papalois, 2003, European journal of pharmacology.

Effect of Guaiazulene on Some Cytochrome P450 Activities. Implication in the Metabolic Activation and Hepatotoxicity of Paracetamol

A. Kourounakis, P. Kourounakis, E. Rekka, 1997, Archiv der Pharmazie.

Temperature-dependence of stress-induced hepatic autophagy

H. Selye, P. Kourounakis, B. Tuchweber, 1977, Experientia.

Prevention of organomercurial intoxication by thyroid deficiency in the rat

S. Szabó, K. Kovács, P. Kourounakis, 1974 .

Enhanced maze performance and reduced oxidative stress by combined extracts of zingiber officinale and ginkgo biloba in the aged rat

C. Mattern, J. Huston, B. Topic, 2002, Neurobiology of Aging.

The impact of α-tocopherol on radiation-induced liver injury

K. Kotzampassi, D. Paramythiotis, N. Harlaftis, 2003 .

Effect of benzopyrone derivatives on drug activity and metabolism

P. Kourounakis, E. Rekka, 1986, European Journal of Drug Metabolism and Pharmacokinetics.

Effect of thymectomy on zoxazolamine paralysis and metabolism in untreated and (PCN) pregnenolone-16alpha-carbonitril- or ACTH-pretreated rats.

S. Szabó, P. Kourounakis, B. Garg, 1975, Archives internationales de pharmacodynamie et de therapie.

Biologic Stress, Oxidative Stress, and Resistance to Drugs: What Is Hidden Behind

K. Tsiakitzis, M. Pantelidou, P. Kourounakis, 2017, Molecules.

Beneficial effect of a novel non-steroidal anti-inflammatory agent with basic character and antioxidant properties on experimental colitis in rats.

I. Andreadou, J. Triantafillidis, A. Papalois, 2002, European journal of pharmacology.

Nitric oxide releasing morpholine derivatives as hypolipidemic and antioxidant agents.

P. Kourounakis, E. Rekka, M. Chrysselis, 2002, Journal of medicinal chemistry.

Protection by catatoxic steroids, phenobarbital and diphenylhydantoin against methaqualone intoxication.

S. Szabó, H. Selye, P. Kourounakis, 1972, Steroids and lipids research.

Effect on active oxygen species of alliin and Allium sativum (garlic) powder.

P. Kourounakis, E. Rekka, 1991, Research communications in chemical pathology and pharmacology.

Investigation of the effect of chamazulene on lipid peroxidation and free radical processes.

A. Kourounakis, P. Kourounakis, E. Rekka, 1996, Research Communications in Molecular Pathology and Pharmacology.

Laser Raman spectra of some representative hormonal steroids

I. Butler, P. Kourounakis, G. Pouskouleli, 1983 .

Preparation and characterization of metal-thiosteroid complexes

T. Theophanides, P. Kourounakis, G. Pouskouleli, 1976 .

Synthesis and Antifungal and Antioxidant Properties of some New 5-Substituted-4-amino(or aryl)-3-mercapto-4(H)-1,2,4-triazoles

P. Marakos, P. Kourounakis, George Athanasiou, 2002, Arzneimittelforschung.

Synthesis of some thiazole derivatives with prospective local anaesthetic activity.

A. Geronikaki, P. Kourounakis, E. Sotiropoulou, 1989, Die Pharmazie.

Pharmacochemistry of Novel Aminoketone Phthalimide, Δ4‐Tetrahydrophthalimide, and Arylsuccinimide Derivatives with Local Anaesthetic Activity

P. Kourounakis, E. Sotiropoulou, Panos N. Kourounakis, 1994, Archiv der Pharmazie.

Compounds against inflammation and oxidative insult as potential agents for neurodegenerative disorders

P. Eleftheriou, P. Kourounakis, E. Rekka, 2012, Medicinal Chemistry Research.

Effect of steroids and diethylstilbestrol on cocaine toxicity, plasma concentrations and urinary excretion.

H. Selye, P. Kourounakis, U. Rapp, 1979, Arzneimittel-Forschung.

Ionization constants, lipophilicity and biological studies of some novel aryl-(amino or hydroxy)ethyl amino ketones with anti-inflammatory activity

D. Hadjipavlou-Litina, P. Kourounakis, E. Rekka, 1992 .

Synthesis and pharmacological action of some N‐alkyl morpholines and their salts

P. Kourounakis, A. Beckett, W. Hunter, 1968, The Journal of pharmacy and pharmacology.

Synthesis and biological studies of some novel antiinflammatory aryl-hydroxy-amino-ketones

D. Hadjipavlou-Litina, P. Kourounakis, E. Rekka, 1991 .

Stress and active oxygen species--effect of alpha-tocopherol on stress response.

K. Tsiakitzis, A. Kourounakis, P. Kourounakis, 2005, Archiv der Pharmazie.

Active Anti-Inflammatory and Hypolipidemic Derivatives of Lorazepam

P. Kourounakis, E. Rekka, P. Theodosis-Nobelos, 2019, Molecules.

Synthesis and Biological Studies of Some Novel Antiinflammatory Aryl- hydroxy-amino-ketones.

D. Hadjipavlou-Litina, P. Kourounakis, E. Rekka, 1991 .

Gabapentin Antioxidant Derivatives with Anti-Inflammatory and Neuroprotective Potency

P. Kourounakis, E. Rekka, A. Gavalas, 2021, Letters in Drug Design & Discovery.

Anti-inflammatory and Hypolipidemic Effect of Novel Conjugates with Trolox and Other Antioxidant Acids.

P. Kourounakis, E. Rekka, P. Theodosis-Nobelos, 2017, Medicinal chemistry (Shariqah (United Arab Emirates)).

Effect of Hydroxyethyl Rutosides and Related Compounds on Lipid Peroxidation and Free Radical Scavenging Activity. Some Structural Aspects

P. Kourounakis, E. Rekka, P. Kourounakis, 1991, The Journal of pharmacy and pharmacology.

Synthesis of Novel Derivatives of Aroylaminoalcohols and 3‐Amino‐substituted 1‐Phenylpropanols with Potential Anti‐inflammatory and Immunomodulating Activities

A. Gavalas, P. Kourounakis, L. Hadjipetrou, 1998, The Journal of pharmacy and pharmacology.

Antioxidant Activity of Guaiazulene and Protection Against Paracetamol Hepatotoxicity in Rats

A. Kourounakis, P. Kourounakis, E. Rekka, 1997, The Journal of pharmacy and pharmacology.