K. Asin

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Studies on D1 and D2 dopamine receptor involvement in conditioned taste aversions

K. Asin, W. Montana, 1989, Pharmacology Biochemistry and Behavior.

Differential effects of serotonergic and catecholaminergic drugs on ingestive behavior

John D. Davis, L. Bednarz, K. Asin, 2005, Psychopharmacology.

A-69024: a non-benzazepine antagonist with selectivity for the dopamine D-1 receptor.

J. Kebabian, L. Bednarz, D. Kerkman, 1989, European journal of pharmacology.

Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa.

L. Bednarz, R. Perner, A. Nikkel, 1995, The Journal of pharmacology and experimental therapeutics.

Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats.

J. D. Davis, D. Brief, K. Asin, 1981, Science.

Lysine vasopressin attenuation of diethyldithiocarbamate-induced amnesia

K. Asin, 1980, Pharmacology Biochemistry and Behavior.

Tetrapeptide CCK-A agonists: effect of backbone N-methylations on in vitro and in vivo CCK activity.

L. Bednarz, B. Bianchi, M. Holladay, 1994, Journal of medicinal chemistry.

Synthesis and biological activity of CCK heptapeptide analogues. Effects of conformational constraints and standard modifications on receptor subtype selectivity, functional activity in vitro, and appetite suppression in vivo.

L. Bednarz, B. Bianchi, M. Holladay, 1992, Journal of medicinal chemistry.

Translational Development Strategies for TAK-063, a Phosphodiesterase 10A Inhibitor

H. Kimura, K. Asin, Kazunori Suzuki, 2020, International Journal of Neuropsychopharmacology.

Alterations in drug induced catalepsy and post-decapitation convulsions following brain and spinal cord depletion of norepinephrine by the neurotoxin DSP-4.

H. Fibiger, K. Asin, D. Wirtshafter, 1982, Life sciences.

Serotonin-immunoreactive projections to the hippocampus from the interpeduncular nucleus in the rat

S. Lorens, K. Asin, D. Wirtshafter, 1986, Neuroscience Letters.

A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey

L. Bednarz, P. A. Gore, A. Nadzan, 1992, Pharmacology Biochemistry and Behavior.

Effects of haloperidol and clozapine on Fos expression in the primate striatum

K. Asin, D. Wirtshafter, 2003, Neuroreport.

Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431.

L. Bednarz, L. Mahan, J. Mikusa, 1996, European journal of pharmacology.

Is dopamine involved in the hyperactivity produced by injections of muscimol into the median raphe nucleus?

K. Asin, D. Wirtshafter, M. Klitenick, 1988, Pharmacology Biochemistry and Behavior.

Behavioral effects of A71623, a highly selective CCK-A agonist tetrapeptide.

L. Bednarz, M. Cullen, P. A. Gore, 1992, The American journal of physiology.

Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo.

M. Michaelides, E. Bayburt, S. Didomenico, 1997, Journal of medicinal chemistry.

A comment on the practice of expressing food and water intake as a proportion of body weight

K. Asin, D. Wirtshafter, 1982, Physiology & Behavior.

Effects of selective CCK receptor agonists on food intake after central or peripheral administration in rats

L. Bednarz, P. A. Gore, M. Holladay, 1992, Brain Research.

Differential effects of CCK-JMV-180 on food intake in rats and mice

L. Bednarz, K. Asin, 1992, Pharmacology Biochemistry and Behavior.

Vortioxetine, a novel antidepressant with multimodal activity: review of preclinical and clinical data.

F. Artigas, C. Sánchez, K. Asin, 2015, Pharmacology & therapeutics.

Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor.

J. Kebabian, R. Mackenzie, R. Perner, 1991, Journal of medicinal chemistry.

Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor.

J. Kebabian, R. Mackenzie, R. Perner, 1991, Journal of medicinal chemistry.

(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist.

J. Kebabian, R. Mackenzie, R. Schoenleber, 1990, Journal of medicinal chemistry.

A68930: A potent agonist specific for the dopamine D1 receptor

J. Kebabian, R. Mackenzie, D. R. Britton, 1992, Neurochemistry International.

A68930: a potent agonist selective for the dopamine D1 receptor.

J. Kebabian, L. Bednarz, C. Briggs, 1991, European journal of pharmacology.

(1R,3S)-1-(Aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2- benzopyran: A Potent and Selective D1 Agonist.

J. Kebabian, R. Mackenzie, R. Schoenleber, 1991 .

The effects of electrolytic median raphe lesions on two measures of latent inhibition.

K. Asin, E. Kent, D. Wirtshafter, 1980, Behavioral and neural biology.

Serotonin depletion and inhibition: Running the rat race without any brakes?

K. Asin, D. Wirtshafter, 1986, Behavioral and Brain Sciences.

Nucleus accumbens lesions reduce amphetamine hyperthermia but not hyperactivity.

K. Asin, E. Kent, D. Wirtshafter, 1978, European journal of pharmacology.

Force requirements in lever-pressing and responding after haloperidol

H. Fibiger, K. Asin, 1984, Pharmacology Biochemistry and Behavior.

Straight alley acquisition and extinction and open field activity following discrete electrolytic lesions of the mesencephalic raphe nuclei.

K. Asin, E. Kent, D. Wirtshafter, 1979, Behavioral and neural biology.

Impaired patterned responding in rats with electrolytic median raphe lesions

K. Asin, E. Kent, D. Wirtshafter, 1979, Physiology & Behavior.

An analysis of neuronal elements within the median nucleus of the raphe that mediate lesion-induced increases in locomotor activity

H. Fibiger, H. C. Fibiger, Karen E. Asin, 1983, Brain Research.

New applications of disease genetics and pharmacogenetics to drug development.

A. Roses, A. Hariri, S. Brannan, 2014, Current opinion in pharmacology.

(5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1- ena[c]-phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431).

M. Michaelides, M. Williams, S. Didomenico, 1995, Journal of medicinal chemistry.

Effects of Low Doses of Pioglitazone on Resting-State Functional Connectivity in Conscious Rat Brain

Zhifeng Liang, Nanyin Zhang, Allen D. Roses, 2015, PloS one.

Spontaneous and delayed spatial alternation following damage to specific neuronal elements within the nucleus medianus raphe

H. Fibiger, K. Asin, 1984, Behavioural Brain Research.

Failure to establish a conditioned place preference with ethanol in rats

B. Tabakoff, K. Asin, D. Wirtshafter, 1985, Pharmacology Biochemistry and Behavior.

A68930: a potent and specific agonist for the D-1 dopamine receptor.

J. Kebabian, C. Briggs, J. McKelvy, 1990, American journal of hypertension.

Dopamine agonists and stress produce different patterns of Fos-like immunoreactivity in the lateral habenula

David Wirtshafter, M. Pitzer, Karen E. Asin, 1994, Brain Research.

Clonidine produces a conditioned place preference in rats

K. Asin, D. Wirtshafter, 2004, Psychopharmacology.

Pentobarbital-induced drinking does not rely on a renal dipsogen

B. Tabakoff, K. Asin, D. Wirtshafter, 1985, Physiology & Behavior.

Dopamine antagonists induce fos-like-immunoreactivity in the substantia nigra and entopeduncular nucleus of the rat

K. Asin, D. Wirtshafter, 1995, Brain Research.

Effects of repeated dopamine D1 receptor stimulation on rotation and c-fos expression.

K. Asin, D. Wirtshafter, 1993, European journal of pharmacology.

Haloperidol induces Fos expression in the globus pallidus and substantia nigra of cynomolgus monkeys

K. Asin, D. Wirtshafter, 1999, Brain Research.

The application of electrophysiological methods to characterize AMPA receptors in dissociated adult rat and non-human primate cerebellar neurons for use in neuronal safety pharmacology assessments of the central nervous system.

S. Authier, M. Curtis, M. Pugsley, 2020, Journal of pharmacological and toxicological methods.

ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease.

L. Mahan, M. Michaelides, P. Jenner, 1996, The Journal of pharmacology and experimental therapeutics.

Repeated D1 receptor agonist treatment blocks cocaine-induced locomotor activity and c-fos expression

A. Nikkel, K. Asin, D. Wirtshafter, 1994, Brain Research.

The selective dopamine D1 receptor agonist A-86929 maintains efficacy with repeated treatment in rodent and primate models of Parkinson's disease.

E. Domino, K. Shiosaki, A. Nikkel, 1997, The Journal of pharmacology and experimental therapeutics.

The Selective Dopamine D 1 Receptor Agonist A-86929 Maintains Efficacy with Repeated Treatment in Rodent and Primate Models of Parkinson ’ s Disease

E. Domino, K. Shiosaki, A. Nikkel, 1997 .

Ingestive behaviors of rats with electrolytic median raphe lesions maintained on a food deprivation schedule

K. Asin, D. Wirtshafter, 1982, Physiology & Behavior.

Impaired radial maze performance in rats with electrolytic median raphe lesions

K. Asin, D. Wirtshafter, 1983, Experimental Neurology.

Simple technique for midline stereotaxic surgery in the rat

K. Asin, E. Kent, D. Wirtshafter, 1979, Physiology & Behavior.

Unilateral dopamine depletion paradoxically enhances amphetamine-induced Fos expression in basal ganglia output structures

K. Asin, D. Wirtshafter, 1999, Brain Research.

Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D1 dopamine receptors in the rat

K. Asin, D. Wirtshafter, 2001, Brain Research.

Haloperidol and nonreinforcement produce different patterns of response slowing in a food reinforced runway task

K. Asin, D. Wirtshafter, 1985, Pharmacology Biochemistry and Behavior.

Development of non-sulfated tetrapeptides as potent and selective CCK-A receptor agonists

B. Bianchi, A. Nadzan, K. Shiosaki, 1991 .

Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636.

L. Bednarz, P. Curzon, B. Bianchi, 1996, The Journal of pharmacology and experimental therapeutics.

Rotation following intranigral injections of a selective D1 or a selective D2 dopamine receptor agonist in rats

K. Asin, W. Montana, 1988, Pharmacology Biochemistry and Behavior.

Evidence for dopamine involvement in reinforcement obtained using a latent extinction paradigm

K. Asin, D. Wirtshafter, 1990, Pharmacology Biochemistry and Behavior.

Behavioral and biochemical studies of the substrates of median raphe lesion induced hyperactivity

K. Asin, W. Montana, D. Wirtshafter, 1986, Physiology & Behavior.

Evidence against serotonin involvement in the hyperactivity produced by injections of muscimol into the median raphe nucleus

M. A. Klitenick, K. Asin, D. Wirtshafter, 1987, Pharmacology Biochemistry and Behavior.

Discrimination learning and reversal following electrolytic lesions of the median raphe nucleus

K. Asin, D. Wirtshafter, 1986, Physiology & Behavior.

Evidence that electrolytic median raphe lesions increase locomotion but not exploration

K. Asin, D. Wirtshafter, 1982, Physiology & Behavior.

Vortioxetine, a novel antidepressant with multimodal activity: review of preclinical and clinical data.

F. Artigas, C. Sánchez, K. Asin, 2015, Pharmacology & therapeutics.

Regional cerebellar choline acetyltransferase activity following peduncular lesions

H. Fibiger, K. Satoh, K. Asin, 2004, Experimental Brain Research.

Dissociation of haloperidol-induced “anhedonia” and catalepsy by lesions of the dorsal raphe nucleus

K. Asin, D. Wirtshafter, 1991, Pharmacology Biochemistry and Behavior.

Shock-induced suppression of drinking following electrolytic median raphe lesions

K. Asin, D. Wirtshafter, 1981 .

Interactive effects of stimulation of D1 and D2 dopamine receptors on fos-like immunoreactivity in the normosensitive rat striatum

K. Asin, D. Wirtshafter, 1994, Brain Research Bulletin.

Evidence that serotonergic projections to the substantia nigra in the rat arise in the dorsal, but not the median, raphe nucleus

T. R. Stratford, K. Asin, D. Wirtshafter, 1987, Neuroscience Letters.

Electrolytic, but not 5,7-dihydroxytryptamine, lesions of the nucleus medianus raphe impair acquisition of a radial maze task.

H. Fibiger, K. Asin, D. Wirtshafter, 1985, Behavioral and neural biology.

Compartmentally specific effects of quinpirole on the striatal Fos expression induced by stimulation of D1-dopamine receptors in intact rats

K. Asin, D. Wirtshafter, G. Schardt, 1997, Brain Research.

Amphetamine induces Fos-like immunoreactivity in the striatum of primates

A. Nikkel, K. Asin, D. Wirtshafter, 1996, Brain Research.