J. R. Morphy

发表

Medicinal Chemistry Strategies to Prevent Compound Attrition

J. R. Morphy, 2015 .

Towards tumour targeting with copper-radiolabelled macrocycle–antibody conjugates: synthesis, antibody linkage, and complexation behaviour

M. Eaton, R. Kataky, C. Walker, 1990 .

Reagent concentration effects in the REM resin solid phase synthesis of tertiary amines

Z. Rankovic, J. R. Morphy, M. York, 2003 .

Fluorocarbon accelerated supported transformations (FAST) on REM resin

Z. Rankovic, J. R. Morphy, M. York, 2001 .

Antibody labelling with functionalised cyclam macrocycles

R. Titmas, M. Eaton, A. Millican, 1988 .

Matrix Metalloproteinase Inhibitors: Current Status

J. R. Porter, J. R. Morphy, T. Millican, 1995, Current Medicinal Chemistry.

Review Oncologic, Endocrine & Metabolic: Recent developments in matrix metalloproteinase inhibitors

J. R. Porter, J. R. Morphy, T. Millican, 1995 .

Implementation of macrocycle conjugated antibodies for tumour-targetting

J. P. Cox, K. Jankowski, D. Parker, 1989 .

Towards tumour targeting with copper-radiolabelled macrocycle–antibody conjugates

M. Eaton, R. Kataky, C. Walker, 1989 .

Identification and optimisation of novel sulfonamide, selective vasopressin V1B receptor antagonists.

F. Thomson, M. Craighead, R. Blackburn-Munro, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.

D. Auld, M. Webb, M. Ohlmeyer, 2011, Bioorganic & medicinal chemistry letters.

Gelatinase inhibitors and tumour metastasis

S. Chander, B. Mason, I. Hart, 1995 .

Potent and selective inhibitors of gelatinase-a 1. hydroxamic acid derivatives

B. Mason, N. Beeley, J. O'Connell, 1994 .

Potent, selective inhibitors of human gelatinase and their potential in the treatment of tumour metastases

S. Chander, B. Mason, I. Hart, 1994 .

The first potent and selective inhibitors of the glycine transporter type 2.

R. McGuire, Z. Rankovic, R. Dickins, 2001, Journal of medicinal chemistry.

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis

R. Paton, John M. Brown, K. Christensen, 2018, Science.

The dual role of thiourea in the thiotrifluoromethylation of alkenes

M. Médebielle, J. R. Morphy, Tanatorn Khotavivattana, 2016, Chemical science.

Synthesis of an array of amides by aluminium chloride assisted cleavage of resin-bound esters

D. Rees, J. R. Morphy, D. Barn, 1996 .

Low dilution procedures in solid-phase organic synthesis: Diels-Alder and Heck reactions

Z. Rankovic, J. R. Morphy, M. York, 2002 .

Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis.

A. Bom, J. R. Morphy, D. Barn, 1999, Bioorganic & medicinal chemistry letters.

General routes for the synthesis of mono, di and tri-n-substituted derivatives of cyclam

D. Parker, J. R. Morphy, I. Helps, 1989 .

A NOVEL LINKER STRATEGY FOR SOLID-PHASE SYNTHESIS

Z. Rankovic, D. Rees, J. R. Morphy, 1996 .

Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist.

Mark A. Weston, M. Ohlmeyer, F. Thomson, 2011, Bioorganic & medicinal chemistry letters.

Synthesis of Tertiary Amines Using a Polystyrene (REM) Resin

D. Rees, Angus R. Brown, J. R. Morphy, 1997 .

Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase.

Morphy, J. Reynolds, J. O'Connell, 1995, The Biochemical journal.

Optimization of reaction conditions for REM resin-bound quaternization reactions.

Z. Rankovic, K. Cameron, J. R. Morphy, 2002, Journal of combinatorial chemistry.

Designing multi-target drugs

J. Richard Morphy, C. Harris, C John Harris, 2012 .

ChEMBLSpace - a graphical explorer of the chemogenomic space covered by the ChEMBL database

George Papadatos, David A. Evans, David A. Thorner, 2013, Bioinform..

General Routes for the Synthesis of Mono‐, Di‐ and Tri‐N‐Substituted Derivatives of Cyclam.

D. Parker, J. R. Morphy, I. Helps, 1989 .

Linkers for solid-phase organic synthesis.

J. R. Morphy, 1998, Current opinion in drug discovery & development.

Design and synthesis of a maximally diverse and druglike screening library using REM resin methodology.

R. McGuire, Z. Rankovic, R. Dickins, 2001, Journal of combinatorial chemistry.

Potent and selective inhibitors of gelatinase-A 2. carboxylic and phosphonic acid derivatives

B. Mason, N. Beeley, B. Boyce, 1994 .