Chiara Bardella

发表

U. Pohl, C. Watts, Victoria Wykes, 2021, International journal of molecular sciences.

Cancer esearch cular and Cellular Pathobiology ression Profiling in Progressive Stages of Fumarate-ratase Deficiency : The Contribution of Metabolic R nges to Tumorigenesis

L. Aaltonen, E. Volpi, B. Spencer‐Dene, 2010 .

University of Birmingham Expression of Idh1(R132H) in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

M. Tomková, H. Lockstone, P. Ratcliffe, 2022 .

Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors

F. Armstrong, C. Schofield, J. McCullagh, 2022, Nature Communications.

Cells Lacking the Fumarase Tumor Suppressor Are Protected from Apoptosis through a Hypoxia-Inducible Factor-Independent, AMPK-Dependent Mechanism

I. Tomlinson, P. Rustin, P. Pollard, 2012, Molecular and Cellular Biology.

SDH mutations in cancer.

I. Tomlinson, P. Pollard, Patrick J. Pollard, 2011, Biochimica et biophysica acta.

ERα as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells

M. Rosenfeld, M. De Bortoli, L. Di Croce, 2009, Proceedings of the National Academy of Sciences.

Mouse Models of Diffuse Lower-Grade Gliomas of the Adult

E. Huillard, Chiara Bardella, Sandra E. Joppé, 2020 .

Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis

C. Ludwig, I. Tomlinson, Y. Mao, 2018, Cell reports.

Molecular and Cellular Pathobiology Expression Profiling in Progressive Stages of Fumarate- Hydratase Deficiency: the Contribution of Metabolic Changes to Tumorigenesis

Ian Tomlinson, Yuen-Li Chung, L. Aaltonen, 2022 .

Mutant IDH in Gliomas: Role in Cancer and Treatment Options

G. Solomou, A. Finch, Chiara Bardella, 2023, Cancers.

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

I. Tomlinson, P. Ratcliffe, V. Buckle, 2012, Nature Genetics.

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

I. Varela, S. Horswell, J. Larkin, 2015, Nature Communications.

p38 MAPK turns hepatocyte growth factor to a death signal that commits ovarian cancer cells to chemotherapy‐induced apoptosis

P. Comoglio, N. Coltella, N. Filigheddu, 2006, International journal of cancer.

Aberrant succination of proteins in fumarate hydratase‐deficient mice and HLRCC patients is a robust biomarker of mutation status

L. Aaltonen, A. Harris, Jennifer M. Taylor, 2011, The Journal of pathology.

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside of the crypt base stem cell niche

M. Bansal, R. Poulsom, I. Tomlinson, 2014, Nature Medicine.

Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells

C. Schofield, J. McCullagh, Elisabete Pires, 2020, Communications Biology.

Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells

C. Schofield, J. McCullagh, Elisabete Pires, 2020, Communications Biology.

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

I. Tomlinson, M. Tomková, H. Lockstone, 2016, Cancer cell.

The role of inflammation in subventricular zone cancer

I. Tomlinson, E. O’Neill, F. Szele, 2018, Progress in Neurobiology.

Truncated RON Tyrosine Kinase Drives Tumor Cell Progression and Abrogates Cell-Cell Adhesion Through E-Cadherin Transcriptional Repression

P. Comoglio, G. Ranzani, M. De Bortoli, 2004, Cancer Research.

Bone morphogenetic protein and Notch signalling crosstalk in poor‐prognosis, mesenchymal‐subtype colorectal cancer

M. Bansal, I. Tomlinson, A. Al Haj Zen, 2017, The Journal of pathology.

Fumarase tumor suppressor gene and MET oncogene cooperate in upholding transformation and tumorigenesis

P. Carmeliet, N. Coltella, M. Olivero, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

HOT mutation screening in human glioblastomas

I. Tomlinson, J. Stebbing, Chiara Bardella, 2015, Future science OA.

IDH mutations in tumorigenesis and their potential role as novel therapeutic targets.

J. Stebbing, A. Frampton, J. Krell, 2013, Future oncology.

The Therapeutic Potential of Hepatocyte Growth Factor to Sensitize Ovarian Cancer Cells to Cisplatin and Paclitaxel In vivo

N. Coltella, M. Mazzone, M. Olivero, 2007, Clinical Cancer Research.

Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH Mutations in Glioblastoma

I. Tomlinson, Chiara Bardella, P. Mulholland, 2011, PloS one.

University of Birmingham The role of inflammation in subventricular zone cancer

Chiara Bardella, Abeer R. Al-Shammari, Luana Soares, 2022 .

Serum- and Glucocorticoid-induced Kinase Sgk1 Directly Promotes the Differentiation of Colorectal Cancer Cells and Restrains Metastasis

I. Tomlinson, S. Irshad, S. Segditsas, 2018, Clinical Cancer Research.

Cells Lacking the Fumarase Tumor Suppressor Are Protected from Apoptosis through a Hypoxia-Inducible Factor-Independent, AMPK-Dependent Mechanism

I. Tomlinson, P. Rustin, Patrick J. Pollard, 2012, Molecular and Cellular Biology.

Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.

L. Aaltonen, B. Spencer‐Dene, K. Howarth, 2010, Cancer research.

CAN-10-1949 Cancer esearch cular and Cellular Pathobiology ression Profiling in Progressive Stages of Fumarate-ratase Deficiency : The Contribution of Metabolic R nges to Tumorigenesis

L. Aaltonen, E. Volpi, B. Spencer‐Dene, 2010 .