Zhimei Li

发表

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma.

Swe Swe Myint, P. Tan, Qiang Yu, 2017, Cancer discovery.

1 VHL deficiency drives enhancer activation of oncogenes in clear cell renal cell carcinoma

Swe Swe Myint, P. Tan, Qiang Yu, 2017 .

Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia

Rosmin Elsa Mohan, H. Ong, B. Teh, 2016, Nature Medicine.

Identification of mangiferin as a potential Glucokinase activator by structure-based virtual ligand screening

Hua Li, Weiguang Sun, Luosheng Wan, 2017, Scientific Reports.

Genomic landscapes of breast fibroepithelial tumors

Swe Swe Myint, P. Tan, Dachuan Huang, 2015, Nature Genetics.

The Multi-Dimensional Biomarker Landscape in Cancer Immunotherapy

C. Ng, J. Chan, T. Ko, 2022, International journal of molecular sciences.

Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities

Michael A. Beer, M. Teh, M. Beer, 2022, Gut.

Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers.

Qiang Yu, Y. Liou, P. Guan, 2011, Molecular cell.

8-Chrysoeriol, as a potential BCL-2 inhibitor triggers apoptosis of SW1990 pancreatic cancer cells.

Lixia Chen, Hua Li, Zhimei Li, 2018, Bioorganic chemistry.

Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma.

Arnoud Boot, K. Soo, Dachuan Huang, 2020, The Journal of clinical investigation.

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

Qiang Yu, Xiaojing Yang, Qiang Yu, 2009, Genes & development.

RASAL2 activates RAC1 to promote triple-negative breast cancer progression.

Qiang Yu, E. Tan, Jinhua Wang, 2014, The Journal of clinical investigation.

RASAL 2 activates RAC 1 to promote triple-negative breast cancer progression

Qiang Yu, E. Tan, Jinhua Wang, 2022 .

B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.

Qiang Yu, S. Hooi, Jing Tan, 2010, Cancer cell.

PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.

Qiang Yu, Jing Tan, Puay Leng Lee, 2013, Cancer discovery.

HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer

B. Teh, Ting-dong Yan, Shang Li, 2019, Gut.

Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML)

Qiang Yu, Jianbiao Zhou, W. Chng, 2015, PloS one.

Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma.

Dachuan Huang, C. Ong, B. Teh, 2017, Blood.

Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis

Qiang Yu, Peiyong Guan, Qiang Yu, 2013, Proceedings of the National Academy of Sciences.

Aberrant JAK-STAT signaling-mediated chromatin remodeling impairs the sensitivity of NK/T-cell lymphoma to chidamide

Dachuan Huang, C. Ong, B. Teh, 2023, Clinical Epigenetics.

EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-driven prostate cancer.

Qiang Yu, Y. Lim, Puay Leng Lee, 2014, Cell reports.

Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.

Michael A. Beer, K. White, H. Grabsch, 2020, The Journal of clinical investigation.

lncRNA TUG 1 promotes cell growth and epithelial-mesenchymal transition in human cervical cancer

Yuxia Gao, Caixia Chen, Zhimei Li, 2016 .

Protein arginine N-methyltransferase 2 reverses tamoxifen resistance in breast cancer cells through suppression of ER-α36

Jing Zhong, Yingying Shen, Xuyu Zu, 2018, Oncology reports.

Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor

P. Tan, B. Teh, Shun-Jie Li, 2022, npj Breast Cancer.

The dietary compound luteolin inhibits pancreatic cancer growth by targeting BCL-2.

Hua Li, Lixia Chen, Zhimei Li, 2018, Food & function.

Effects of breast fibroepithelial tumor associated retinoic acid receptor alpha ligand binding domain mutations on receptor function and retinoid signaling

P. Tan, B. Teh, D. Rhodes, 2022, bioRxiv.

Multiomic analysis and immunoprofiling

Arnoud Boot, K. Soo, Dachuan Huang, 2020 .

Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2

Weiguang Sun, Lixia Chen, Meng-zhu Zheng, 2017, Journal of experimental & clinical cancer research : CR.

P1-25-3INHIBITION OF RECTAL CANCER GROWTH BY A NEW HERBAL EXTRACT COMBINATIONS(FUO-C4) IN VIVO

W. Yin, Hong Liu, Ya-Chung Tian, 2014 .

An amphiphilic tetraphenylethylene-based photosensitizer for cancer cell ablation and bacteria killing

Yong Chen, Zhimei Li, Shixian Wen, 2022, Dyes and pigments.

Oncogenic activation of JAK3-STAT signaling confers clinical sensitivity to PRN371, a novel selective and potent JAK3 inhibitor, in natural killer/T-cell lymphoma

J. M. Bradshaw, Dachuan Huang, C. Ong, 2018, Leukemia.

Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2

Weiguang Sun, Lixia Chen, Meng-zhu Zheng, 2017, Journal of Experimental & Clinical Cancer Research.

Myc/miR-378/TOB2/cyclin D1 functional module regulates oncogenic transformation

Qiang Yu, Mengling Feng, Q. Yu, 2011, Oncogene.

PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma

W. Tam, Dachuan Huang, B. Teh, 2023, Nature Cell Biology.

Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia

Rosmin Elsa Mohan, H. Ong, B. Teh, 2016, Nature Medicine.

RASAL2 activates RAC1 to promote triple-negative breast cancer progression.

Qiang Yu, E. Tan, Jinhua Wang, 2014, The Journal of clinical investigation.

Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies

S. Dima, C. Yong, C. Pairojkul, 2023, Gut.