P. Abraham

发表

Structure-activity relationship of trihexyphenidyl analogs with respect to the dopamine transporter in the on going search for a cocaine inhibitor.

G. Uhl, F. Carroll, A. Gamliel, 2005, European journal of medicinal chemistry.

Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.

J. L. Howard, M. Kuhar, G. T. Pollard, 2004, Journal of medicinal chemistry.

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction.

H. Navarro, F. Carroll, B. Blough, 2009, Journal of medicinal chemistry.

Selective labeling of the dopamine transporter by the high affinity ligand 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester.

J. Cadet, F. Carroll, A. Lewin, 1995, Molecular pharmacology.

Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.

N. Volkow, J. Fowler, M. Kuhar, 1997, Journal of medicinal chemistry.

Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product.

J. Deschamps, J. Flippen-Anderson, M. Kuhar, 2005, Bioorganic & medicinal chemistry.

Synthesis of mercapto-(+)-methamphetamine haptens and their use for obtaining improved epitope density on (+)-methamphetamine conjugate vaccines.

S. M. Owens, J. Lay, F. Carroll, 2011, Journal of medicinal chemistry.

Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.

M. Kuhar, F. Carroll, B. Blough, 1996, Journal of medicinal chemistry.

Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.

M. Kuhar, F. Carroll, A. Lewin, 1994, Journal of medicinal chemistry.

Generation of anti-(+)methamphetamine antibodies is not impeded by (+)methamphetamine administration during active immunization of rats.

S. M. Owens, F. Carroll, K. Byrnes-Blake, 2001, International immunopharmacology.

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues.

L. Brieaddy, H. Navarro, F. Carroll, 2001, Journal of medicinal chemistry.

Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.

F. Ivy Carroll, H. Navarro, M. Damaj, 2007, Bioorganic & medicinal chemistry.

Synthesis of 2-(3-Substituted-1,2,4-oxadiazol-5-yl)-8-methyl-8-azabicyclo[3.2.1]octanes and 2α-(3-Substituted-1,2,4-oxadiazol-5-yl)-8-methyl-8-azabicyclo[3.2.1]oct-2-enes as Potential Muscarinic Agonists

Yong Wha Kwon, D. Triggle, F. Carroll, 1992, Pharmaceutical Research.

Isopropyl and phenyl esters of 3 beta-(4-substituted phenyl)tropan-2 beta-carboxylic acids. Potent and selective compounds for the dopamine transporter.

M. Kuhar, F. Carroll, A. Lewin, 1992, Journal of medicinal chemistry.

[123/125I]RTI‐55, an in vivo label for the serotonin transporter

M. Kuhar, R. Dannals, G. Ricaurte, 1992, Synapse.

Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.

M. Kuhar, H. Navarro, F. Carroll, 2005, Journal of medicinal chemistry.

Synthesis and transporter binding properties of ( R)-2 ,3 - and ( R)-2 a,3 a-diaryltropanes

M. Kuhar, F. Carroll, Songchun Jiang, 1998 .

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues.

L. Brieaddy, H. Navarro, F. Carroll, 2001, Journal of medicinal chemistry.

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist.

L. Brieaddy, H. Navarro, F. Carroll, 2001, Journal of medicinal chemistry.

Enantiomeric N-substituted N-normetazocines: a comparative study of affinities at sigma, PCP, and mu opioid receptors.

S. Mascarella, F. Carroll, B. Martin, 1992, Journal of medicinal chemistry.

Selective dopamine transporter inhibition by cocaine analogs.

M. Kuhar, F. Carroll, A. Lewin, 1992, Neuroreport.

3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogues of cocaine: affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters.

M. Kuhar, F. Carroll, A. Lewin, 1993, Journal of medicinal chemistry.

Synthesis and muscarinic receptor activity of ester derivatives of 2-substituted 2-azabicyclo[2.2.1]heptan-5-ol and -6-ol.

D J Triggle, F I Carroll, P Abraham, 1992, Journal of medicinal chemistry.

Synthesis and stereoselective reduction of (±)-, (+)- and (-)-6-substituted-6-azabicyclo[3.2.1]octan-3-one

David J. Triggle, Philip Abraham, J. Bruce Pitner, 1991 .

The synthesis of haptens and their use for the development of monoclonal antibodies for treating methamphetamine abuse.

S. M. Owens, J. Lay, F. Carroll, 2009, Journal of medicinal chemistry.

Synthesis, molecular modeling studies, and muscarinic receptor activity of azaprophen analogues.

J. B. Pitner, D. Triggle, S. Mascarella, 1991, Journal of medicinal chemistry.

6-Methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agent.

P. Chiang, F. Carroll, R. Griffith, 1987, Journal of medicinal chemistry.

New synthesis of 7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]hept-2-ene. A key intermediate in the synthesis of epibatidine and analogs

L. Brieaddy, F. Carroll, Jeffrey R. Lee, 1998 .

5-ETHYL-5-(1-METHYL-3-CARBOXYPROPYL)-BARBITURIC ACID

F. Carroll, P. Abraham, 1970 .

Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3β-(4-[125I]iodophenyl) tropan-2β-carboxylic acid isopropyl ester ([125I]RTM-21)

M. Kuhar, F. Carroll, B. Thomas, 1996 .

2 beta-substituted analogues of cocaine. Synthesis and inhibition of binding to the cocaine receptor.

M. Kuhar, F. Carroll, A. Lewin, 1992, Journal of medicinal chemistry.

3α-(4‘-Substituted phenyl)tropane- 2β-carboxylic Acid Methyl Esters: Novel Ligands with High Affinity and Selectivity at the Dopamine Transporter

M. Kuhar, F. Carroll, P. Abraham, 1996 .

Synthesis, Ligand Binding, and Quantitative Structure−Activity Relationship Study of 3β-(4‘-Substituted phenyl)-2β-heterocyclic Tropanes: Evidence for an Electrostatic Interaction at the 2β-Position

M. Kuhar, S. Mascarella, F. Carroll, 1996 .

Synthesis and Ligand Binding Study of 3β-(4′-Substituted phenyl)- 2β-(heterocyclic)tropanes.

M. Kuhar, S. Mascarella, F. Carroll, 1995 .

Synthesis and ligand binding study of 3 beta-(4'-substituted phenyl)-2 beta-(heterocyclic)tropanes.

M. Kuhar, S. Mascarella, F. Carroll, 1995, Journal of medicinal chemistry.

Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.

M. Kuhar, F. Carroll, A. Dehghani, 1995, Journal of medicinal chemistry.

Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.

F I Carroll, P Abraham, S W Mascarella, 1994, Journal of medicinal chemistry.

3b-(4'-Chlorophenyl)tropan-2b-carboxamides and Cocaine Amide Analogues: New High Affinity and Selective Compounds for the Dopamine Transporter

M. Kuhar, F. Carroll, A. Lewin, 1992 .

Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.

M. Kuhar, R. Lew, F. Carroll, 1992, Journal of medicinal chemistry.

N-modified analogues of cocaine: synthesis and inhibition of binding to the cocaine receptor.

J. B. Pitner, M. Kuhar, F. Carroll, 1992, Journal of medicinal chemistry.

Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters.

F I Carroll, P Abraham, M. Kuhar, 1991, Journal of medicinal chemistry.

Synthesis and ligand binding of cocaine isomers at the cocaine receptor.

F I Carroll, P Abraham, M. Kuhar, 1991, Journal of medicinal chemistry.

Synthesis and Ligand Binding of 3b-(3-Substituted Phenyl)- and 3b-(3,4-Disubstituted Phenyl)Tropane-2b-Carboxylic Acid Methyl Esters

M. Kuhar, F. Carroll, A. Lewin, 1990 .

Synthesis and cocaine receptor affinities of 3-phenyl-2-(3′-methyl-1,2,4-oxadiazole-5′-yl)tropane isomers

M. Kuhar, F. Carroll, A. Lewin, 1993 .

(3S)-3-Hydroxyquinidine, the major biotransformation product of quinidine, synthesis and conformational studies. X-ray molecular structure of (3S)-3-hydroxyquinidine methanesulphonate

S. Mascarella, F. Carroll, P. Abraham, 1991 .

Pharmacodynamic mechanisms of monoclonal antibody-based antagonism of (+)-methamphetamine in rats.

S. M. Owens, R. Landes, F. Carroll, 2003, European journal of pharmacology.

Effects of Murine-Derived Anti-Methamphetamine Monoclonal Antibodies on (+)-Methamphetamine Self-Administration in the Rat

F. Carroll, D. McMillan, M. Gunnell, 2004, Journal of Pharmacology and Experimental Therapeutics.

Synthesis of the 2β,3α- and 2β,3β-isomers of 3-(p-substituted phenyl)tropane-2-carboxylic acid methyl esters

F. Carroll, A. Lewin, P. Abraham, 1995 .

Synthesis of the isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester. A new class of ligands for the dopamine transporter

M. Kuhar, F. Carroll, M. Thiruvazhi, 1997 .

Synthesis of the 2β,3α‐ and 2β,3β‐Isomers of 3‐(p‐ Substituted phenyl)tropane‐2‐carboxylic Acid Methyl Esters

F. Carroll, A. Lewin, P. Abraham, 1995 .

3 Beta-(4-ethyl-3-iodophenyl)nortropane-2 beta-carboxylic acid methyl ester as a high-affinity selective ligand for the serotonin transporter.

M. Kuhar, F. Carroll, B. Blough, 1997, Journal of medicinal chemistry.

In vitro and in vivo characterization of [125I]iodomethyllycaconitine in the rat

H. Navarro, F. Carroll, P. Abraham, 2002, Synapse.

Synthesis and pharmacological characterization of [(125)I]iodomethyllycaconitine ([(125)I]iodo-MLA). A new ligand for the alpha(7) nicotinic acetylcholine receptor.

H. Navarro, F. Carroll, P. Abraham, 2000, Journal of medicinal chemistry.

High‐affinity binding of [125I]RTI‐55 to dopamine and serotonin transporters in rat brain

F I Carroll, P Abraham, M. Kuhar, 1992, Synapse.

Mapping dopamine transporters in the human brain with novel selective cocaine analog [125I]RTI‐121

F I Carroll, P Abraham, D. Mash, 1995, Synapse.

Radiosynthesis of a photoaffinity probe for the cocaine receptor of the dopamine transporter : 3β-(p-chlorophenyl)tropan-2β-carboxylic acid m-([125I]-iodo)-p-azidophenethyl ester ([125I]-RTI-82)

R. Lew, F. Carroll, A. Lewin, 1993 .

N‐substituted phenyltropanes as in vivo binding ligands for rapid imaging studies of the dopamine transporter

F I Carroll, P Abraham, M. Kuhar, 1997, Synapse.

In vivo binding of [125I] RTI‐55 to dopamine transporters: Pharmacology and regional distribution with autoradiography

F I Carroll, P Abraham, M. Kuhar, 1992, Synapse.

Synthesis of [3H]win 35,065-2; A new radioligand for cocaine receptors

M. Kuhar, F. Carroll, A. Lewin, 1990 .

[125I]3b-(4-Iodophenyl)tropan-2b-carboxylic Acid Methyl Ester (RTI-55), A Unique Cocaine Receptor Ligand for Imaging the Dopamine and Serotonin Transporters in Vivo

D. Wong, M. Kuhar, R. Dannals, 1990 .

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation.

R. Lukas, S. Mascarella, H. Navarro, 2009, Journal of medicinal chemistry.