J. R. Brashler

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Inhibition of the leukotriene synthetase of rat basophil leukemia cells by diethylcarbamazine, and synergism between diethylcarbamazine and piriprost, a 5-lipoxygenase inhibitor.

M. K. Bach, J. R. Brashler, 1986, Biochemical pharmacology.

Inhibition by sulfasalazine of LTC synthetase and of rat liver glutathione S-transferases.

M. K. Bach, M. Johnson, J. R. Brashler, 1985, Biochemical pharmacology.

Solubilization and characterization of the leukotriene C4 synthetase of rat basophil leukemia cells: a novel, particulate glutathione S-transferase.

M. K. Bach, D. R. Morton, J. R. Brashler, 1984, Archives of biochemistry and biophysics.

Leukotriene C synthetase, a special glutathione S-transferase: properties of the enzyme and inhibitor studies with special reference to the mode of action of U-60,257, a selective inhibitor of leukotriene synthesis.

M. K. Bach, D. R. Morton, J. R. Brashler, 1984, The Journal of allergy and clinical immunology.

Superoxide production by human eosinophils can be inhibited in an agonist-selective manner

M. K. Bach, M. Sanders, M. E. Sanders, 2005, Agents and Actions.

Pitfalls in the quantitative estimation of the secretion of granule proteins by eosinophils.

M. K. Bach, M. Sanders, M. Bienkowski, 1991, Journal of immunological methods.

Evidence that granulocyte/macrophage-colony-stimulating factor and interferon-gamma maintain the viability of human peripheral blood monocytes in part by their suppression of IL-10 production.

M. K. Bach, J. R. Brashler, 1995, International archives of allergy and immunology.

IgE immune complexes induce immediate and prolonged release of leukotriene C4 (LTC4) from rat alveolar macrophages.

P. Askenase, M. K. Bach, J. Rankin, 1984, Journal of immunology.

IgE-dependent release of leukotriene C4 from alveolar macrophages

P. Askenase, M. K. Bach, J. Rankin, 1982, Nature.

Airway recruitment of leukocytes in mice is dependent on alpha4-integrins and vascular cell adhesion molecule-1.

J. Chin, G. Winterrowd, R. Krzesicki, 1997, The American journal of physiology.

On the structure of slow reacting substance of anaphylaxis: evidence of biosynthesis from arachidonic acid.

M. K. Bach, R. Gorman, J. R. Brashler, 1977, Prostaglandins.

Determination of leukotriene C4 by radioimmunoassay with a specific antiserum generated from a synthetic hapten mimic.

M. K. Bach, F. Fitzpatrick, D. R. Morton, 1984, Analytical chemistry.

Slow reacting substances: comparison of some properties of human lung SRS-A and two distinct fractions from ionophore-induced rat mononuclear cell SRS.

M. K. Bach, J. R. Brashler, C. D. Brooks, 1979, Journal of immunology.

Identification of leukotriene C-1 as a major component of slow-reacting substance from rat mononuclear cells.

B. Samuelsson, M. K. Bach, J. R. Brashler, 1980, Journal of immunology.

Identification of a component of rat mononuclear cell SRS as leukotriene D.

B. Samuelsson, M. K. Bach, J. R. Brashler, 1980, Biochemical and biophysical research communications.

Ionophore A 23187-induced production of slow reacting substance of anaphylaxis (SRS-A) by rat peritoneal cells in vitro: evidence for production by mononuclear cells.

M. K. Bach, J. R. Brashler, 1978, Journal of immunology.

Preparation of large numbers of highly purified normodense human eosinophils from leukapheresis.

M. K. Bach, M. Sanders, J. R. Brashler, 1990, Journal of immunological methods.

Phenotypic analysis of airway eosinophils and lymphocytes in a Th-2-driven murine model of pulmonary inflammation.

S. Holgate, J. Chin, G. Winterrowd, 1996, American journal of respiratory cell and molecular biology.

Generation of lipoxygenase metabolites of arachidonic acid by monolayer cultures of tracheal epithelial cells and intact tracheal segments from rabbits.

M. K. Bach, J. R. Brashler, S. Alpert, 1990, Experimental lung research.

6,9-deepoxy-6,9,-(phenylimino)-delta 6,8-prostaglandin I1, (U-60,257), a new inhibitor of leukotriene C and D synthesis: in vitro studies.

M. K. Bach, F. Fitzpatrick, F. Sun, 1982, Prostaglandins.

Intercellular adhesion molecule-1-deficient mice have antibody responses but impaired leukocyte recruitment.

J. Chin, G. Winterrowd, J. R. Brashler, 1997, The American journal of physiology.

On the nature of the presumed receptor for IgE on mast cells. I. The effect of sialidase and phospholipase C treatment on the capacity of rat peritoneal cells to participate in IgE-mediated, antigen-induced histamine release in vitro.

M. K. Bach, J. R. Brashler, 1973, Journal of immunology.

Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer’s disease

D. D. McKinley, J. Chin, R. Krzesicki, 2001, Brain Research Bulletin.

Experiments on the mode of action of piriprost (U-60,257), an inhibitor of leukotriene formation in cloned mouse mast cells and in rat basophil leukemia cells.

S. Galli, M. K. Bach, J. R. Brashler, 1987, Biochemical pharmacology.

In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis.

M. K. Bach, F. Fitzpatrick, F. Sun, 1983, Advances in prostaglandin, thromboxane, and leukotriene research.

Two rat mononuclear cell-derived slow reacting substances: kinetic evidence that the peripheral airways-selective spasmogen is derived from a nonselectively acting precursor.

J. Drazen, M. K. Bach, M. Johnson, 1980, Immunopharmacology.

A family of calcium ionophore-induced slow reacting substances produced by rat mononuclear cells: enhancement of production with different mercaptans results in formation of different products.

M. K. Bach, J. R. Brashler, 1979, International journal of immunopharmacology.

M. K. Bach, M. Sanders, T. Ishizaka, 1990, International archives of allergy and applied immunology.

On the nature of the presumed receptor for IgE on mast cells. V. Enhanced binding of 125I-labeled IgE to cell-free particulate fractions in the presence of protease inhibitors.

M. K. Bach, K. Ishizaka, T. Ishizaka, 1973, International archives of allergy and applied immunology.

Solubilization and characterization of the leukotriene C4 synthetase of rat basophil leukemia cells: a novel, particulate glutathione S-transferase.

M. K. Bach, D. R. Morton, J. R. Brashler, 1984, Archives of biochemistry and biophysics.

Inhibition of rat liver glutathione S-transferases by piriprost: kinetics of the inhibition and preliminary evidence that piriprost may be a poor alternative substrate for these enzymes.

M. K. Bach, M. Johnson, J. O'Brien, 1985, Research communications in chemical pathology and pharmacology.

Preclinical evaluation of anti-inflammatory activities of the novel pyrrolopyrimidine PNU-142731A, a potential treatment for asthma.

J. Chin, G. Winterrowd, R. Krzesicki, 1999, The Journal of pharmacology and experimental therapeutics.

1,4-Dihydronaphthoquinones, hydroindoloquinones, benzofurans, and benzothiophenes as inhibitors of 5-lipoxygenase. Synthesis and structure-activity studies.

M. K. Bach, R. Schaub, M. Holm, 1990, Journal of medicinal chemistry.

Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

Alfredo G. Tomasselli, Mark E. Gurney, Allen E. Buhl, 1999, Nature.

Isolation of subpopulations of lymphocytic cells by the use of isotonically balanced solutions of Ficoll. I. Development of methods and demonstration of the existence of a large but finite number of subpopulations.

M. K. Bach, J. R. Brashler, 1970, Experimental Cell Research.

Subpopulations within "short-lived" and "long-lived" lymphocytes resolved by isopycnic sedimentation in Ficoll solutions coupled with a double radioisotopic labeling technique.

M. K. Bach, J. R. Brashler, 1970, Experimental cell research.

Inhibition of IgE and compound 48/80-induced histamine release by lectins.

M. K. Bach, J. R. Brashler, 1975, Immunology.

Activity of mouse reaginic antibodies in the rat: passive cutaneous anaphylaxis and in vitro passive histamine release.

M. K. Bach, J. R. Brashler, 1973, Immunological communications.

Identification of cytokine and adhesion molecule mRNA in murine lung tissue and isolated T cells and eosinophils by semi-quantitative reverse transcriptase-polymerase chain reaction.

J. Chin, G. Winterrowd, R. Krzesicki, 1997, American journal of respiratory cell and molecular biology.

Role of very late activation antigen-4 in the antigen-induced accumulation of eosinophils and lymphocytes in the lungs and airway lumen of sensitized brown Norway rats.

J. Chin, G. Winterrowd, R. Krzesicki, 1996, American journal of respiratory cell and molecular biology.

Involvement of intercellular adhesion molecule-1 in the antigen-induced infiltration of eosinophils and lymphocytes into the airways in a murine model of pulmonary inflammation.

J. Chin, G. Winterrowd, R. Krzesicki, 1998, American journal of respiratory cell and molecular biology.

1,4-Dihydronaphthoquinones as water-soluble inhibitors of 5-lipoxygenase.

M. K. Bach, R. Schaub, M. Holm, 1990, Prostaglandins, leukotrienes, and essential fatty acids.

SEL‐10 interacts with presenilin 1, facilitates its ubiquitination, and alters A‐beta peptide production

M. Gurney, C. Ruble, Jinhe Li, 2002, Journal of neurochemistry.

Activation of human eosinophils by platelet-derived growth factor.

M. K. Bach, M. Sanders, M. Bienkowski, 1992, International archives of allergy and immunology.

Platelet-derived growth factor can activate purified primate, phorbol myristate acetate-primed eosinophils.

M. K. Bach, M. Sanders, H. G. Johnson, 1991, International archives of allergy and applied immunology.

Formation of leukotrienes C and D and Pharmacologic modulation of their synthesis.

M. Kaliner, M. K. Bach, T. Hugli, 1982, Advances in prostaglandin, thromboxane, and leukotriene research.

A comparison of the leukotriene synthesizing ability of subfractions of rat liver glutathione S-transferases.

M. K. Bach, J. R. Brashler, 1985, Prostaglandins Leukotrienes and Medicine.

In vivo and in vitro production of a slow reacting substance in the rat upon treatment with calcium ionophores.

M. K. Bach, J. R. Brashler, 1974, Journal of immunology.

Stimulated production of slow reacting substances by mercaptans from ionophore A 23187-induced mononuclear cells: mercaptan structure-activity studies.

M. K. Bach, J. R. Brashler, 1978, Life sciences.

Isolation of hapten-specific antibodies from reagin-rich rat sera and their use for the preparation of rat peritoneal cells for antigen-mediated histamine release.

M. K. Bach, D. Stechschulte, J. R. Brashler, 1973, Immunochemistry.

Role of intercellular adhesion molecule-1 in antigen-induced lung inflammation in brown Norway rats.

D. Anderson, J. Chin, G. Winterrowd, 1996, The American journal of physiology.

On the nature of the presumed receptor for IgE on mast cells. II. Demonstration of the specific binding of IgE to cell-free particulate preparations from rat peritoneal mast cells.

M. K. Bach, J. R. Brashler, 1973, Journal of immunology.