S. Townson

发表

Evaluation of drugs against Onchocerca microfiliariae in an inbred mouse model.

A. E. Bianco, M. Nwachukwu, S. Townson, 1986, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro

A. Hoerauf, Alexandra Ehrens, M. Hübner, 2020, PLoS neglected tropical diseases.

Challenges in drug discovery for novel antifilarials

S. Nwaka, S. Townson, Bernadette Ramirez, 2007, Expert opinion on drug discovery.

Onchocerca parasites and Wolbachia endosymbionts: evaluation of a spectrum of antibiotic types for activity against Onchocerca gutturosa in vitro

Mark J. Taylor, Helen F. McGarry, S. Townson, 2006, Filaria journal.

Integrated Dataset of Screening Hits against Multiple Neglected Disease Pathogens

Simon Townson, Timothy Geary, Jean-Marc Paris, 2011, PLoS neglected tropical diseases.

Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Citation

Alessandro, Serge, Tyler B. Hughes, 2016 .

Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside

A. Hoerauf, G. Verocai, A. Wolstenholme, 2021, International journal for parasitology. Drugs and drug resistance.

Host strain, H-2 genotype and immunocompetence do not affect the survival or development of Onchocerca lienalis infective larvae implanted within micropore chambers into mice or rats

M. Taylor, A. E. Bianco, S. Townson, 1992, Parasitology.

Immunity to Onchocerca lienalis microfilariae in mice

G. Nelson, A. E. Bianco, S. Townson, 1985, Journal of Helminthology.

Enterprise Architecture and Business Transformation: The Difference and Synergy Potential.

Robert Winter, Axel Uhl, Nils Labusch, 2012 .

Antiparasitic properties of medicinal plants and other naturally occurring products.

S. Townson, S. Tagboto, 2001, Advances in parasitology.

Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization

A. Hoerauf, J. Siekierka, Alexandra Ehrens, 2022, International journal for parasitology. Drugs and drug resistance.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Manuel Llinás, George Papadatos, Sundari Suresh, 2016, PLoS pathogens.

Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections

A. Hoerauf, S. Menon, Alexandra Ehrens, 2022, Journal of medicinal chemistry.

2-acetylpyridine thiosemicarbazones. 13. Derivatives with antifilarial activity.

S. Y. Wang, K. Kinnamon, J. Mccall, 1991, Journal of medicinal chemistry.

Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration

J. Keiser, L. Holden-Dye, S. Hahnel, 2021, PLoS pathogens.

Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside

J. Keiser, A. Jex, R. Gasser, 2014, PLoS neglected tropical diseases.

Comparison of the sensitivity of different geographical isolates of Onchocerca volvulus microfilariae to ivermectin: effects of exposure to drug on development in the blackfly Simulium ornatum.

V. Titanji, K. Awadzi, S. Townson, 1994, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Immune responses of the argasid tick Ornithodoros moubata moubata induced by infection with the filarial worm Acanthocheilonema viteae

A. Reid, S. Townson, D. Hutton, 2000, Journal of Helminthology.

An improved technique for the cryopreservation of Onchocerca microfilariae

E. James, S. Townson, P. Ham, 1981, Parasitology.

Developmentally regulated expression and secretion of a polymorphic antigen by Onchocerca infective-stage larvae.

B. Robertson, Y. Kuo, S. Townson, 1990, Molecular and biochemical parasitology.

Comparison of the sensitivity of different geographical races of Onchocerca volvulus microfilariae to ivermectin: studies in vitro.

A. Lujan, V. Titanji, K. Awadzi, 1994, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Whence river blindness? The domestication of mammals and host-parasite co-evolution in the nematode genus Onchocerca.

G. Verocai, D. Otranto, B. Makepeace, 2017, International journal for parasitology.

Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis

B. Slatko, A. Hoerauf, S. Ward, 2013, Parasitology.

Study on the activity of antiparasitic agents against Onchocerca lienalis third stage larvae in vitro.

S. Townson, E. Friedheim, P. Ham, 1985, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi

M. Taylor, L. Hollick, S. Townson, 2000 .

Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi.

M. Taylor, L. Hollick, S. Townson, 2000, Annals of tropical medicine and parasitology.

Onchocerca volvulus and O. lienalis: the microfilaricidal activity of moxidectin compared with that of ivermectin in vitro and in vivo.

S Townson, S K Tagboto, S. Townson, 1996, Annals of tropical medicine and parasitology.

Onchocerca lienalis: comparison of techniques for the cryopreservation of microfilariae within skin-snips or free of host tissues

S. Townson, S. Tagboto, 1991, Journal of Helminthology.

The effects of ivermectin on the viability of Onchocerca lienalis microfilariae in vitro and on their subsequent development in the blackfly vector, Simulium ornatum.

S. Townson, S. Tagboto, 1991, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

Optimization of culture conditions for the maintenance of Onchocerca gutturosa adult worms in vitro

C. Connelly, S. Townson, R. Muller, 1986, Journal of Helminthology.

Artificial feeding and successful reproduction inOrnithodoros moubata moubata (Murray, 1877) (Acarina: Argasidae)

S. Townson, D. Hutton, E. Schwan, 1991, Experimental & Applied Acarology.

Drug activity against Onchocerca gutturosa males in vitro: a model for chemotherapeutic research on onchocerciasis

C. Connelly, S. Townson, R. Muller, 1987, Journal of Helminthology.

Immunization of calves against the microfilariae of Onchocerca lienalis

S. Townson, A. Bianco, 1982, Journal of Helminthology.

Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis

A. Hoerauf, R. Altmeyer, S. Specht, 2014, International journal for parasitology. Drugs and drug resistance.

Immunity to onchocerca lienalis microfilariae in mice. I. Resistance induced by the homologous parasite.

S. Townson, M. Doenhoff, R. Muller, 1984, Tropenmedizin und Parasitologie.

Experimental infection of mice with the microfilariae of Onchocerca lienalis

S. Townson, A. Bianco, 1982, Parasitology.

The effects of ivermectin used in combination with other known antiparasitic drugs on adult Onchocerca gutturosa and O. volvulus in vitro.

S. Townson, G. Zea-Flores, J. Townsend, 1990, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Chemotherapy of Onchocerca lienalis microfilariae in mice: a model for the evaluation of novel compounds for the treatment of onchocerciasis

C. Connelly, S. Townson, R. Muller, 1988, Journal of Helminthology.

In vitro cultivation and development of Onchocerca volvulus and Onchocerca lienalis microfilariae.

S. Townson, S. Tagboto, 1996, The American journal of tropical medicine and hygiene.

Protective immunity against Onchocerca volvulus and O. lienalis infective larvae in mice.

M. Taylor, S. Townson, S. Folkard, 1994, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

The further application of MTT-formazan colorimetry to studies on filarial worm viability.

J. Comley, S. Townson, M. Rees, 1989, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

Onchocerca gutturosa and O. volvulus: studies on the viability and drug responses of cryopreserved adult worms in vitro.

C. Connelly, J. Comley, S. Townson, 1989, Transactions of the Royal Society of Tropical Medicine and Hygiene.

The development of a laboratory model for onchocerciasis using Onchocerca gutturosa: in vitro culture, collagenase effects, drug studies and cryopreservation.

S. Townson, 1988, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

A semi-automated system of intrathoracic injection for the large-scale production of Onchocerca lienalis infective larvae.

G. Nelson, S. Townson, P. Ham, 1989, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

Attempts to infect small laboratory animals with the infective larvae of Onchocerca lienalis

D. Owen, S. Townson, A. Bianco, 1981, Journal of Helminthology.

Evidence for the occurrence of respiratory electron transport in adult Brugia pahangi and Dipetalonema viteae.

A. Mendis, S. Townson, 1985, Molecular and biochemical parasitology.

Improved development of Brugia microfilariae following cryopreservation in liquid nitrogen using a technique suitable for field conditions.

S. Townson, P. Ham, Simon Townson, 1986, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Enterprise Architecture and Transformation: The Differences and the Synergy Potential of Enterprise Architecture and Business Transformation Management

Robert Winter, Axel Uhl, Nils Labusch, 2013 .

Challenges in drug discovery for novel antifilarials

S. Nwaka, S. Townson, Bernadette Ramirez, 2007, Expert opinion on drug discovery.