Jessica Orf

发表

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Deepali V. Sawant, Xueda Hu, J. Egen, 2020, Cell.

Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment

J. Egen, J. DeVoss, Brian Belmontes, 2021, Cancer Immunology, Immunotherapy.

Methylthioadenosine (MTA) Rescues Methylthioadenosine Phosphorylase (MTAP)-Deficient Tumors from Purine Synthesis Inhibition in Vivo via Non-Autonomous Adenine Supply

A. Kamb, M. Rong, Jianxia Shi, 2011 .

Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines.

R. Hungate, M. Rong, W. Zhong, 2010, Bioorganic & medicinal chemistry letters.

Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists.

R. Hungate, M. Rong, W. Zhong, 2010, Bioorganic & medicinal chemistry letters.

Small Molecule Therapeutics Preclinical Evaluation of AMG 925 , a FLT 3 / CDK 4 Dual Kinase Inhibitor for Treating Acute Myeloid Leukemia

A. Kamb, Ji Ma, J. Medina, 2014 .

The optimization of aminooxadiazoles as orally active inhibitors of Cdc7.

T. Bush, M. Rong, K. Sham, 2013, Bioorganic & medicinal chemistry letters.

Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit.

R. Hungate, M. Rong, W. Zhong, 2011, Bioorganic & medicinal chemistry letters.

Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth

Yongchang Shi, Yu-Chien Chou, K. Yamaguchi, 2011, Molecular Cancer Therapeutics.

Preclinical Evaluation of AMG 925, a FLT3/CDK4 Dual Kinase Inhibitor for Treating Acute Myeloid Leukemia

Alexander Kamb, John Eksterowicz, C. Quéva, 2014, Molecular Cancer Therapeutics.

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1.

S. Powers, L. See, K. Nguyen, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Generation of bone marrow chimeras using X-ray irradiation: comparison to cesium irradiation and use in immunotherapy

Deepali V. Sawant, J. DeVoss, J. Eng, 2020, Journal of biological methods.

Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity

J. Egen, J. DeVoss, S. Novitskiy, 2022, Cancer Immunology, Immunotherapy.

Preclinical Development Cabozantinib ( XL 184 ) , a Novel MET and VEGFR 2 Inhibitor , Simultaneously Suppresses Metastasis , Angiogenesis , and Tumor Growth

K. Yamaguchi, J. Lesch, F. Yakes, 2011 .

Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth

K. Yamaguchi, F. Yakes, A. Joly, 2011, Molecular Cancer Therapeutics.

Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit.

R. Hungate, M. Rong, W. Zhong, 2011, Bioorganic & medicinal chemistry letters.