P. Ward

发表

Identification and Disruption of Two Discrete Loci Encoding Hyaluronic Acid Capsule Biosynthesis GeneshasA, hasB, and hasC inStreptococcus uberis

E. Maguin, J. Leigh, P. Ward, 2001, Infection and Immunity.

Mutation of a putative ADP‐ribosylation motif in the Pasteurella multocida toxin does not affect mitogenic activity

E. Rozengurt, P. Mullan, A. Lax, 1994, FEBS letters.

Lipoprotein Signal Peptides Are Processed by Lsp and Eep of Streptococcus uberis

E. Denham, J. Leigh, P. Ward, 2008, Journal of bacteriology.

Structural characterisation of a nanobody derived from a naïve library that neutralises SARS-CoV-2

J. Naismith, P. Rijal, Yuguang Zhao, 2020 .

Localization of MtuA, an LraI homologue in Streptococcus uberis

J. Leigh, P. Ward, A. Smith, 2004, Journal of applied microbiology.

Identification of a Differentially Expressed Oligopeptide Binding Protein (OppA2) in Streptococcus uberis by Representational Difference Analysis of cDNA

L. Bowler, J. Leigh, P. Ward, 2003, Journal of bacteriology.

Differential Protein Expression in Streptococcus uberis under Planktonic and Biofilm Growth Conditions

H. Lappin-Scott, L. Bowler, R. C. Crowley, 2010, Applied and Environmental Microbiology.

Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis

B. Barrell, A. Bignell, M. Quail, 2009, BMC Genomics.

Hyperinvasive Neonatal Group B Streptococcus Has Arisen from a Bovine Ancestor

T. Peto, D. Crook, R. Harding, 2004, Journal of Clinical Microbiology.

Vru (Sub0144) controls expression of proven and putative virulence determinants and alters the ability of Streptococcus uberis to cause disease in dairy cattle

M. Watson, S. Egan, J. Leigh, 2012, Microbiology.

Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility

H. Lavender, S. Lea, R. Exley, 2014, eLife.

Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes

R. Owens, M. Vendruscolo, D. Clare, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Cryptic SARS-CoV2-spike-with-sugar interactions revealed by 'universal' saturation transfer analysis — Source link

Panagiotis I. Koukos, R. Owens, Q. Sattentau, 2022 .

Identification of Novel Neisseria gonorrhoeae Lineages Harboring Resistance Plasmids in Coastal Kenya

M. Maiden, S. Graham, E. Sanders, 2018, The Journal of infectious diseases.

Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

Steven W. Johnson, D. Staunton, E. Goicoechea de Jorge, 2012, PLoS pathogens.

Streptococcus agalactiae infection in dairy cows.

J. Hillerton, T. Coffey, J. Leigh, 2004, The Veterinary record.

Sortase anchored proteins of Streptococcus uberis play major roles in the pathogenesis of bovine mastitis in dairy cattle

T. Coffey, S. Egan, J. Leigh, 2010, Veterinary research.

Lack of vessel wall elastolysis in human invasive pulmonary aspergillosis

D. Denning, L. Fenelon, E. Benbow, 1992, Infection and immunity.

The exploitation of the genome in the search for determinants of virulence in Streptococcus uberis.

J. Leigh, P. Ward, T. R. Field, 2004, Veterinary immunology and immunopathology.

MtuA, a Lipoprotein Receptor Antigen from Streptococcus uberis, Is Responsible for Acquisition of Manganese during Growth in Milk and Is Essential for Infection of the Lactating Bovine Mammary Gland

J. Leigh, P. Ward, T. R. Field, 2003, Infection and Immunity.

The Hyaluronic Acid Capsule of Streptococcus uberis Is Not Required for the Development of Infection and Clinical Mastitis

J. Leigh, P. Ward, T. R. Field, 2003, Infection and Immunity.

Activity of the Mitogenic Pasteurella multocida Toxin Requires an Essential C-Terminal Residue

A. Miles, I. Sumner, A. Lax, 1998, Infection and Immunity.

A single base mutation in the gene for type III collagen (COL3A1) converts glycine 847 to glutamic acid in a family with Ehlers-Danlos syndrome type IV. An unaffected family member is mosaic for the mutation

J. Lloyd, P. Narcisi, A. Nicholls, 1992, Human Genetics.

A 27-bp deletion from one allele of the type III collagen gene (COL3A1) in a large family with Ehlers-Danlos syndrome type IV

A. Paepe, J. Lloyd, P. Narcisi, 2004, Human Genetics.

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

R. Owens, D. Stuart, D. Clare, 2020, Nature Structural & Molecular Biology.

In the absence of Lgt, lipoproteins are shed from Streptococcus uberis independently of Lsp.

E. Denham, J. Leigh, P. Ward, 2009, Microbiology.

Characterisation of a glycine to valine substitution at amino acid position 910 of the triple helical region of type III collagen in a patient with Ehlers-Danlos syndrome type IV.

A. De Paepe, J. Lloyd, P. Narcisi, 1991, Journal of medical genetics.

The molecular basis of regulation of bacterial capsule assembly by Wzc

C. Robinson, Peijun Zhang, C. Whitfield, 2021, Nature Communications.

A Comparative Structure/Function Analysis of Two Type IV Pilin DNA Receptors Defines a Novel Mode of DNA Binding

S. Matthews, S. Lea, J. Berry, 2016, Structure.

Richard D Emes, Ray Wilson, Maqsud Hossain, 2015, BMC Genomics.

Correction: Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

Steven W. Johnson, D. Staunton, E. Goicoechea de Jorge, 2013, PLoS Pathogens.

Rapid Evolution of Virulence and Drug Resistance in the Emerging Zoonotic Pathogen Streptococcus suis

I. Goodhead, M. Quail, K. Mungall, 2009, PloS one.

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

R. Owens, D. Stuart, D. Clare, 2020, Nature Structural & Molecular Biology.

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

Jordan J. Clark, R. Owens, J. Stewart, 2021, Nature Communications.

Structural consideration of the formation of the activation complex between the staphylokinase-like streptococcal plasminogen activator PadA and bovine plasminogen.

A. Abu-Median, J. Leigh, P. Ward, 2008, Journal of molecular biology.

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

R. Owens, D. Stuart, D. Clare, 2020, Nature Structural & Molecular Biology.

Identification of sortase A (SrtA) substrates in Streptococcus uberis: evidence for an additional hexapeptide (LPXXXD) sorting motif.

L. Hunt, S. Egan, J. Leigh, 2010, Journal of proteome research.

Complex interactions between bovine plasminogen and streptococcal plasminogen activator PauA.

A. Abu-Median, J. Leigh, P. Ward, 2004, Journal of molecular biology.

Cryptic pathogen-sugar interactions revealed by universal saturation transfer analysis

R. Owens, Q. Sattentau, J. Naismith, 2021, bioRxiv.

Epithelial invasion and cell lysis by virulent strains of Streptococcus suis is enhanced by the presence of suilysin.

R. W. Bentley, C. Rolph, J. Leigh, 1999, FEMS immunology and medical microbiology.

The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex

C. Whitfield, J. Naismith, D. Bhella, 2023, Open Biology.

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

R. Owens, D. Stuart, D. Clare, 2020, Nature Structural & Molecular Biology.

Genetic analysis of Streptococcus uberis plasminogen activators.

J. Leigh, P. Ward, 2004, The Indian journal of medical research.

Isolation and characterization of a mutant strain of Streptococcus uberis, which fails to utilize a plasmin derived β‐casein peptide for the acquisition of methionine

J. Leigh, P. Ward, A. Kitt, 2002, Journal of applied microbiology.

The Activation of Bovine Plasminogen by PauA Is Not Required for Virulence of Streptococcus uberis

J. Leigh, P. Ward, T. R. Field, 2003, Infection and Immunity.

Generation and Characterization of a Defined Mutant of Streptococcus suis Lacking Suilysin

D. Maskell, H. Lindsay, J. Leigh, 2001, Infection and Immunity.

Characterization of PauB, a Novel Broad-Spectrum Plasminogen Activator from Streptococcus uberis

J. Leigh, P. Ward, 2002, Journal of bacteriology.

Identification of multiple linear epitopes of the plasminogen activator A (PauA) of Streptococcus uberis with murine monoclonal antibodies.

D. S. McVey, Jishu Shi, J. Leigh, 2005, Veterinary immunology and immunopathology.

PauA: a novel plasminogen activator from Streptococcus uberis.

J. Leigh, R. Yancey, P. Ward, 1999, FEMS microbiology letters.

Richard D Emes, Ray Wilson, Maqsud Hossain, 2015, BMC Genomics.

A Paradox in Bacterial Pathogenesis: Activation of the Local Macrophage Inflammasome Is Required for Virulence of Streptococcus uberis

Richard D Emes, M. F. Addis, Nathan Archer, 2020, Pathogens.

Pathogen-sugar interactions revealed by universal saturation transfer analysis

Panagiotis I. Koukos, R. Owens, Q. Sattentau, 2022, Science.

A Comparative Structure/Function Analysis of Two Type IV Pilin DNA Receptors Defines a Novel Mode of DNA Binding

S. Matthews, S. Lea, J. Berry, 2016, Structure.