P. Duchaussoy

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1 INFLUENCE OF HEPARIN MIMETICS ON THE ASSEMBLY OF THE FGF-FGFR 4 SIGNALING COMPLEX

K. Saxena, H. Schwalbe, M. Mohammadi, 2010 .

Synthesis of conformationally locked L-iduronic acid derivatives: direct evidence for a critical role of the skew-boat 2S0 conformer in the activation of antithrombin by heparin.

J. Herbert, J. Hérault, J. Mallet, 2001, Chemistry.

Synthesis of thrombin-inhibiting heparin mimetics without side effects

J. Herbert, M. Petitou, J. Lormeau, 1999, Nature.

Synthesisof thrombin-inhibitingheparinmimetics without sideeffects

J. Herbert, M. Petitou, J. Lormeau, 2022 .

A synthetic heparan sulfate pentasaccharide, exclusively containing L-iduronic acid, displays higher affinity for FGF-2 than its D-glucuronic acid-containing isomers.

J. Herbert, M. Salmivirta, J. Kovensky, 1999, Bioorganic & medicinal chemistry.

Experimental proof for the structure of a thrombin-inhibiting heparin molecule.

S. Pérez, J. Herbert, J. Hérault, 2001, Chemistry.

New synthetic heparin mimetics able to inhibit thrombin and factor Xa.

J. Herbert, J. Hérault, M. Petitou, 1999, Bioorganic & medicinal chemistry letters.

Synthesis of heparin fragments: A methyl α-pentaoside with high affinity for antithrombin III☆

G. Torri, M. Petitou, J. Choay, 1987 .

The first total synthesis of the antithrombin III binding site of porcine mucosa heparin

P. Lei, M. Petitou, J. Choay, 1991 .

Biologically active heparin-like fragments with a “non-glycosamino”glycan structure. Part 3 : o-alkylated-o-sulphated pentasaccharides.

C. V. Boeckel, J. Basten, P. Duchaussoy, 1992 .

Total synthesis of a heparin pentasaccharide fragment having high affinity for antithrombin III

G. Torri, M. Petitou, J. Choay, 1984 .

Synthesis of Conformationally Locked Carbohydrates: A Skew-Boat Conformation of L-Iduronic Acid Governs the Antithrombotic Activity of Heparin.

J. Herbert, S. Das, J. Mallet, 2001, Angewandte Chemie.

Synthesis of a 3-deoxy-L-iduronic acid containing heparin pentasaccharide to probe the conformation of the antithrombin III binding sequence.

P. Lei, J. Mallet, M. Petitou, 1998, Bioorganic & medicinal chemistry.

Synthesis of heparin fragments. A chemical synthesis of the trisaccharide O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-α-d-glucopyranosyl)-(1→4)-O-(2-O-sulfo-α-l-idopyranosyluronic acid)-(1→4)-2-deoxy-2-sulfamido-6-O-sulfo-d-glucopyranose heptasodium salt

G. Torri, M. Petitou, J. Choay, 1984 .

First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin.

J. Herbert, C. V. van Boeckel, M. Petitou, 1998, Angewandte Chemie.

Total synthesis of a heparin pentasaccharide fragment having high affinity for antithrombin III

G. Torri, M. Petitou, J. Choay, 1984 .

The Synthetic Pentasaccharide Fondaparinux: First in the Class of Antithrombotic Agents that Selectively Inhibit Coagulation Factor Xa

J. Herbert, J. Necciari, M. Petitou, 2002, Seminars in thrombosis and hemostasis.

Synthesis of heparin fragments: a methyl alpha-pentaoside with high affinity for antithrombin III.

G. Torri, M. Petitou, J. Choay, 1987, Carbohydrate research.

Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

J. Herbert, L. Millet, J. Hérault, 2008, Journal of thrombosis and haemostasis : JTH.

Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients

J. Herbert, J. Hérault, P. Savi, 2003, Journal of thrombosis and haemostasis : JTH.

Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540).

J. Herbert, J. Hérault, M. Petitou, 1997, Journal of medicinal chemistry.

The Structure of Synthetic Oligosaccharides in Relation to Factor IXa Inhibition

J. Herbert, J. Hérault, F. Bono, 2002, Thrombosis and Haemostasis.

Identification of a hexasaccharide sequence able to inhibit thrombin and suitable for 'polymerisation'.

J. Herbert, M. Petitou, P. Duchaussoy, 1999, Carbohydrate research.

Assessment through chemical synthesis of the size of the heparin sequence involved in thrombin inhibition.

J. Herbert, M. Petitou, M. Ceccato, 1999, Carbohydrate research.

Synthetic oligosaccharides having various functional domains: potent and potentially safe heparin mimetics.

J. Herbert, J. Hérault, M. Petitou, 1999, Bioorganic & medicinal chemistry letters.

Synthesis and anti-thrombin activity of a hexasaccharide corresponding to the binding site of dermatan sulfate to heparin cofactor II

J. Herbert, J. Hérault, J. Mallet, 1997 .

L-iduronic acid derivatives as glycosyl donors.

J. Mallet, M. Petitou, P. Duchaussoy, 1996, Carbohydrate research.

Binding of heparin to antithrombin III: a chemical proof of the critical role played by a 3-sulfated 2-amino-2-deoxy-D-glucose residue.

M. Petitou, J. Choay, P. Duchaussoy, 1988, Carbohydrate research.

p-Anisyl ethers in carbohydrate chemistry: Selective protection of the primary alcohol function

M. Petitou, J. Choay, P. Duchaussoy, 1988 .

A synthetic heparin/heparan sulfate-like decasaccharide releases lipase activity in vivo. Chemical synthesis and biological activity

J. Herbert, P. Hoffmann, M. Petitou, 1997 .

Synthesis of Conformationally Locked L-Iduronic Acid Derivatives. Direct Evidence for a Critical Role of the Skew-Boat 2S0 Conformer in the Activation of Antithrombin by Heparin.

J. Herbert, S. Das, J. Mallet, 2002 .

Synthesis of heparin fragments. A chemical synthesis of the pentasaccharide O-(2-deoxy-2-sulfamido-6-O-sulfo-alpha-D-glucopyranosyl)-(1-4 )-O-(beta-D-glucopyranosyluronic acid)-(1-4)-O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-alpha-D-glu copyranosyl)-(1-4)-O-(2-O-sulfo-alpha-L-idopyranosyluronic acid)-(1

G. Torri, M. Petitou, J. Choay, 1986, Carbohydrate research.

A new, highly potent, heparin-like pentasaccharide fragment containing a glucose residue instead of a glucosamine

M. Petitou, J. Choay, P. Duchaussoy, 1991 .

SR123781A, a Synthetic Heparin Mimetic

J. Herbert, J. Hérault, P. Savi, 2001, Thrombosis and Haemostasis.

First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin.

J. Herbert, C. V. van Boeckel, M. Petitou, 1998, Angewandte Chemie.

Synthesis of Heparin Fragments. A Chemical Synthesis of the Pentasaccharide O-(2-Deoxy-2-sulfamido-6-O-sulfo-α-D-glucopyranosyl)-(l->4)-O-(β-glucopyranosyluronic acid)-(1->4)-O-(2-deoxy-2-sulfamido-3,6-di-O- sulfo-α-D-glucopyranosyl)-

G. Torri, M. Petitou, J. Choay, 1986 .

Influence of Heparin Mimetics on Assembly of the FGF·FGFR4 Signaling Complex

K. Saxena, H. Schwalbe, M. Mohammadi, 2010, The Journal of Biological Chemistry.

Influence of Heparin Mimetics on Assembly of the FGF·FGFR4 Signaling Complex

K. Saxena, H. Schwalbe, M. Mohammadi, 2010, The Journal of Biological Chemistry.

Binding of heparan sulfate to fibroblast growth factor-2 total synthesis of a putative pentasaccharide binding site

J. Kovensky, M. Petitou, P. Duchaussoy, 1996 .