R. Edom

发表

Recent advances in application of hydrophilic interaction chromatography for quantitative bioanalysis.

Naidong Weng, Wenying Jian, R. Edom, 2010, Journal of separation science.

LC‐MS in Drug Metabolism and Pharmacokinetics: A Pharmaceutical Industry Perspective

Mingshe Zhu, Naidong Weng, Wenying Jian, 2012 .

Potential bias and mitigations when using stable isotope labeled parent drug as internal standard for LC-MS/MS quantitation of metabolites.

Naidong Weng, Wenying Jian, R. Edom, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

LC‐MS Bioanalysis of Endogenous Compounds as Biomarkers

Naidong Weng, Wenying Jian, R. Edom, 2013 .

Quantitation of leukotriene B(4) in human sputum as a biomarker using UPLC-MS/MS.

A. Fourie, Naidong Weng, Wenying Jian, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Method qualification for tissue bioanalysis

Shefali R Patel, Naidong Weng, R. Edom, 2013 .

Development and validation of an LC-MS/MS based method for quantification of 25 hydroxyvitamin D2 and 25 hydroxyvitamin D3 in human serum and plasma.

Naidong Weng, Wenying Jian, R. Edom, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Separation and quantification of two diastereomers of a Drug Candidate in rat plasma by ultra-high pressure liquid chromatography/mass spectrometry.

Sanjeev Kumar, R. Edom, S. Vincent, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Chromatographic Separation Methods

Naidong Weng, Wenying Jian, R. Edom, 2012 .

Analysis of polar metabolites by hydrophilic interaction chromatography--MS/MS.

Naidong Weng, Wenying Jian, R. Edom, 2011, Bioanalysis.

An electron-capture dienophile derivatization agent for increasing sensitivity: determination of a vitamin D analog (Ro 24-2090) in plasma samples with liquid chromatography/mass spectrometry.

R. Edom, L. Gabriel, T. Crews, 1996, Analytical biochemistry.

Bio-generation of stable isotope labeled internal standards for absolute and relative quantitation of drug metabolites in plasma samples by LC-MS/MS.

Naidong Weng, Wenying Jian, Rhys Salter, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Important considerations for quantitation of small-molecule biomarkers using LC-MS.

Naidong Weng, Wenying Jian, R. Edom, 2012, Bioanalysis.

Validation and application of an LC-MS/MS method for quantitation of three fatty acid ethanolamides as biomarkers for fatty acid hydrolase inhibition in human plasma.

Hao Wang, Naidong Weng, Hao Wang, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Mini FocuS iSSue : tieRed appRoach to BioanalySiS

Naidong Weng, Wenying Jian, R. Edom, 2014 .

Problems and Solutions in Quantitative Determination of Drugs and Metabolites in Physiological Specimens by LC-MS/MS

R. Foltz, R. Edom, 1998 .

Kinetics of oral fluphenazine disposition in humans by GC-MS

K. Midha, G. Mckay, R. Edom, 2004, European Journal of Clinical Pharmacology.

Dehalogenation reactions in the fast atom bombardment mass spectrometry of phenothiazine‐related drugs

K. Midha, J. Hubbard, G. Mckay, 1991 .

Identification of a hydroxy metabolite of diflunisal in rat and human urine.

R. Verbeeck, R. Dickinson, R. Edom, 1991, Xenobiotica; the fate of foreign compounds in biological systems.

LC-ESI-MS/MS quantification of 4β-hydroxycholesterol and cholesterol in plasma samples of limited volume.

Yang Yuan, Naidong Weng, David C. Evans, 2013, Journal of pharmaceutical and biomedical analysis.

Simultaneous measurement of fluphenazine and [2H4]fluphenazine in plasma using solids probe tandem mass spectrometry

K. Midha, G. Mckay, R. Edom, 1995 .

Subnanogram determination of fluphenazine in human plasma by gas chromatography mass spectrometry.

K. Midha, G. Mckay, R. Edom, 1983, Biomedical mass spectrometry.

Determination of Ro 19-6327 (Lazabemide) in human plasma and urine by gas chromatography-negative chemical ionization mass spectrometry.

R. Edom, T. Crews, P. P. Davis, 1995, Journal of chromatography. B, Biomedical applications.

Determination of norgestimate and its metabolites in human serum using high-performance liquid chromatography with tandem mass spectrometric detection.

F. Wong, R. Edom, S. Juzwin, 1999, Journal of chromatography. B, Biomedical sciences and applications.

Quantitative determination of Orlistat (tetrahydrolipostatin, Ro 18-0647) in human plasma by high-performance liquid chromatography coupled with ion spray tandem mass spectrometry.

J. Henion, P. Bennett, R. Edom, 1997, Journal of mass spectrometry : JMS.

Relative quantitation of glycoisoforms of intact apolipoprotein C3 in human plasma by liquid chromatography-high-resolution mass spectrometry.

Naidong Weng, Wenying Jian, R. Edom, 2013, Analytical chemistry.

Quantitation of the enantiomers of rimantadine and its hydroxylated metabolites in human plasma by gas chromatography/mass spectrometry.

R. Edom, N. Choma, E. Fukuda, 1992, Biomedical chromatography : BMC.

Evaluation of a high-throughput online solid phase extraction-tandem mass spectrometry system for in vivo bioanalytical studies.

Naidong Weng, Wenying Jian, R. Edom, 2011, Analytical chemistry.

Bioanalysis of chiral compounds during drug development using a tiered approach.

Naidong Weng, Wenying Jian, R. Edom, 2014, Bioanalysis.

Validation of (-)-N-3-benzyl-phenobarbital as a selective inhibitor of CYP2C19 in human liver microsomes.

A. D. Rodrigues, T. Baillie, D. Dean, 2004, Drug metabolism and disposition: the biological fate of chemicals.