Ž. Svedružić

发表

The Binding of Different Substrate Molecules at the Docking Site and the Active Site of γ-Secretase Can Trigger Toxic Events in Sporadic and Familial Alzheimer’s Disease

Ž. Svedružić, V. S. Jengić, Lucija Ostojić, 2022, bioRxiv.

Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia

I. Jurak, Ž. Svedružić, Noa Čemeljić, 2021, Archives of Virology.

DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition.

N. Reich, Ž. Svedružić, 2005, Biochemistry.

In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1

Ž. Svedružić, V. Miletić, Ivica Odorčić, 2017, PloS one.

Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation.

Ž. Svedružić, 2008, Current medicinal chemistry.

The mechanism of target base attack in DNA cytosine carbon 5 methylation.

N. Reich, Ž. Svedružić, 2004, Biochemistry.

Polyoxometalates as Effective Nano-inhibitors of Amyloid Aggregation of Pro-inflammatory S100A9 Protein Involved in Neurodegenerative Diseases

Himanshu Chaudhary, V. Smirnovas, C. Ohlin, 2021, ACS applied materials & interfaces.

Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase

Christopher H. Chang, Ž. Svedružić, D. Svedružić, 2020, Scientific Reports.

Dnmt1 structure and function.

Ž. Svedružić, 2011, Progress in molecular biology and translational science.

Interaction between mammalian glyceraldehyde‐3‐phosphate dehydrogenase and L‐lactate dehydrogenase from heart and muscle

H. O. Spivey, Ž. Svedružić, H. Spivey, 2006, Proteins.

Accommodation and repair of a UV photoproduct in DNA at different rotational settings on the nucleosome surface.

M. Smerdon, Ž. Svedružić, J. Kosmoski, 2005, The Journal of Biological Chemistry.

Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly

Himanshu Chaudhary, V. Smirnovas, L. Morozova-Roche, 2021, International journal of molecular sciences.

Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer’s Disease

M. Bucciantini, M. Stefani, Jonathan Pansieri, 2021, ACS chemical neuroscience.

Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs.

A. Gräslund, Jonathan Pansieri, M. Magzoub, 2019, ACS chemical biology.

Mechanism of allosteric regulation of Dnmt1's processivity.

N. Reich, Ž. Svedružić, 2005, Biochemistry.

Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein

M. Kozak, A. Gräslund, W. Kwiatek, 2021, Scientific Reports.

Chapter 5 – In Silico Optimization of the First DNA-Independent Mechanism-Based Inhibitor of Mammalian DNA Methyltransferase DNMT1

Ž. Svedružić, V. Miletić, Ivica Odorčić, 2016 .

Decrease in catalytic capacity of γ-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease

V. Šendula-Jengić, Ž. Svedružić, K. Popović, 2015, Molecular and Cellular Neuroscience.

Insilico optimization of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt 1

Ž. Svedružić, V. Miletić, Ivica Odorčić, 2022 .

Dnmt 1 : Structure and Function

Ž. Svedružić, 2011 .

The Prion Protein Octarepeat Domain Forms Transient β-sheet Structures Upon Residue-Specific Cu(II) and Zn(II) Binding

M. Kozak, A. Gräslund, A. Szymańska, 2021, bioRxiv.

High-throughput Virtual Screening Web Service Development for SARS-CoV-2 Drug Design

Martina Asenbrener Katic, Vedran Miletić, Martina Ašenbrener Katić, 2020, 2020 43rd International Convention on Information, Communication and Electronic Technology (MIPRO).

Modulators of γ-Secretase Activity Can Facilitate the Toxic Side-Effects and Pathogenesis of Alzheimer's Disease

V. Šendula-Jengić, Ž. Svedružić, K. Popović, 2013, PloS one.

Structural Analysis of the Simultaneous Activation and Inhibition of γ-Secretase Activity in the Development of Drugs for Alzheimer’s Disease

Ž. Svedružić, V. Miletić, Katarina Vrbnjak, 2021, Pharmaceutics.

Structural Analysis of Simultaneous Activation and Inhibition of γ-Secretase Activity in Development of Drugs for Alzheimer’s disease

Ž. Svedružić, V. Miletić, Katarina Vrbnjak, 2020 .

Accommodation and Repair of a UV Photoproduct in DNA at Different Rotational Settings on the Nucleosome Surface*

M. Smerdon, Ž. Svedružić, J. Kosmoski, 2005, Journal of Biological Chemistry.

Modulation of γ-Secretase Activity by Multiple Enzyme-Substrate Interactions: Implications in Pathogenesis of Alzheimer's Disease

V. Šendula-Jengić, Ž. Svedružić, I. Smoljan, 2012, PloS one.

Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu(II) and Zn(II) Ions

M. Kozak, A. Gräslund, A. Szymańska, 2023, Biochemistry.

Determination of the specific radioactivity of [14C]lactate by enzymatic decarboxylation and 14CO2 collection.

H. O. Spivey, Ž. Svedružić, E. A. Lehoux, 1997, Analytical biochemistry.

Binding Interactions of Fatty Acyl Lipid Mediators Within the Vanilloid Pocket of TRPV1: A Molecular Dynamics Study

C. Reynolds, Ž. Svedružić, D. Visentin, 2023, Prostaglandins & Other Lipid Mediators.

ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9

J. Gilthorpe, V. Smirnovas, S. Jayaweera, 2024, International journal of molecular sciences.

Structural Analysis of Simultaneous Activation and Inhibition of γ-Secretase Activity in Development of Drugs for Alzheimer’s disease

Ž. Svedružić, V. Miletić, Katarina Vrbnjak, 2020, bioRxiv.