M. Nishikawa

发表

Immunological properties of myosin light-chain kinases.

R. Adelstein, P. de Lanerolle, M. Nishikawa, 1987, Biochimica et biophysica acta.

Increased phosphorylation of myosin light chain kinase after an increase in cyclic AMP in intact smooth muscle.

R. Adelstein, P. de Lanerolle, D. A. Yost, 1984, Science.

Calmodulin and acidic compounds alter basic protein phosphorylation by the protein kinase from human platelets.

H. Hidaka, T. Yamaki, M. Nishikawa, 1982, Biochimica et biophysica acta.

The role of Ca2+-dependent protein phosphorylation in platelet aggregation

H. Hidaka, M. Nishikawa, Y. Sasaki, 1980 .

Hemostatic Abnormalities in Patients With Thrombotic Complications on Maintenance Hemodialysis

E. Gabazza, H. Shiku, H. Wada, 2000, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

1. Molecular Mechanisms and Characteristics of Antiplatelet Drugs

M. Nishikawa, S. Tamaru, 2009 .

Intensive or standard blood pressure control in patients with a history of ischemic stroke: RESPECT post hoc analysis

Tokyo, Kazumichi Yoshida, K. Kario, 2022, Hypertension Research.

Possible involvement of bcl‐2 in regulation of cell‐cycle progression of haemopoietic cells by transforming growth factor‐β1

N. Mahmud, H. Shiku, Y. Komada, 1999, British journal of haematology.

Risk of bleeding and repeated bleeding events in prasugrel-treated patients: a review of data from the Japanese PRASFIT studies

S. Saito, Takeshi Kimura, H. Ogawa, 2017, Cardiovascular Intervention and Therapeutics.

Apixaban for the Treatment of Japanese Subjects With Acute Venous Thromboembolism (AMPLIFY-J Study).

I. Komuro, H. Ogawa, I. Kitajima, 2015, Circulation journal : official journal of the Japanese Circulation Society.

Efficacy and Safety of Adjusted-Dose Prasugrel Compared With Clopidogrel in Japanese Patients With Acute Coronary Syndrome

S. Saito, K. Kitagawa, Takeshi Kimura, 2014 .

Prasugrel, a third-generation P2Y12 receptor antagonist, in patients with coronary artery disease undergoing elective percutaneous coronary intervention.

S. Saito, K. Kitagawa, Takeshi Kimura, 2014, Circulation journal : official journal of the Japanese Circulation Society.

Antialbuminuric effect of eplerenone in comparison to thiazide diuretics in patients with hypertension

Tomomi Yamada, T. Kitamura, Masaaki Ito, 2017, Journal of clinical hypertension.

Down‐regulation by retinoic acid of the catalytic subunit of protein phosphatase type 2A during granulocytic differentiation of HL‐60 cells

T. Kuno, C. Tanaka, M. Nagao, 1993, FEBS letters.

Phosphorylation of mammalian myosin light chain kinases by the catalytic subunit of cyclic AMP-dependent protein kinase and by cyclic GMP-dependent protein kinase.

T. Lincoln, R. Adelstein, P. de Lanerolle, 1984, The Journal of biological chemistry.

Haemostatic abnormalities and thrombotic disorders in malignant lymphoma

Y. Abe, J. Nishioka, H. Shiku, 2004, Thrombosis and Haemostasis.

Alteration of intracellular actin levels induced by phorboldiester in human HL-60 leukemia cells susceptible or resistant to differentiation, and the effects of protein kinase inhibitors.

S. Shirakawa, M. Nishikawa, Y. Uemura, 1989, Leukemia research.

Re-evaluation of Bleeding Events in the Japanese PRASFIT-Elective andPRASFIT-ACS Clinical Trials using the Bleeding Academic ResearchConsortium Criteria

S. Saito, Takeshi Kimura, H. Ogawa, 2015 .

Association between High Platelet Reactivity Following Dual Antiplatelet Therapy and Ischemic Events in Japanese Patients with Coronary Artery Disease Undergoing Stent Implantation

A. Hirayama, H. Yokoi, T. Takayama, 2020, Journal of atherosclerosis and thrombosis.

Effects of CYP2C19 allelic variants on inhibition of platelet aggregation and major adverse cardiovascular events in Japanese patients with acute coronary syndrome: The PRASFIT-ACS study.

S. Saito, K. Kitagawa, Takeshi Kimura, 2016, Journal of cardiology.

Relationship between CYP2C19 loss-of-function polymorphism and platelet reactivities with clopidogrel treatment in Japanese patients undergoing coronary stent implantation.

T. Tanigawa, K. Nakatani, Masaaki Ito, 2013, Circulation journal : official journal of the Japanese Circulation Society.

Future prospective of phosphodiesterase-3 inhibitors as antithorombotic drug

H. Hidaka, M. Nishikawa, 2011 .

Efficacy and safety of adjusted-dose prasugrel compared with clopidogrel in Japanese patients with acute coronary syndrome: the PRASFIT-ACS study.

S. Saito, K. Kitagawa, Takeshi Kimura, 2014, Circulation journal : official journal of the Japanese Circulation Society.

Plasma sFas and sFas ligand levels in patients with thrombotic thrombocytopenic purpura and in those with disseminated intravascular coagulation

H. Shiku, H. Wada, K. Nishii, 1999, American journal of hematology.

lcw , 25-Dihydroxyvitamin D ,-Induced Upregulation of Calcineurin During Leukemic HL-60 Cell Differentiation

Serdar, T. Kuno, H. Shiku, 2002 .

1 alpha,25-dihydroxyvitamin D3-induced upregulation of calcineurin during leukemic HL-60 cell differentiation.

T. Kuno, H. Shiku, M. Nishikawa, 1996, Blood.

HER2-Specific T-Cell Immune Responses in Patients Vaccinated with Truncated HER2 Protein Complexed with Nanogels of Cholesteryl Pullulan

A. Scott, L. Old, T. Kanematsu, 2006, Clinical Cancer Research.

Impact of Arterial Access Route on Bleeding Complications in Japanese Patients Undergoing Percutaneous Coronary Intervention- Insight From the PRASFIT Trial.

S. Saito, Takeshi Kimura, H. Ogawa, 2015, Circulation journal : official journal of the Japanese Circulation Society.

No association between on-treatment platelet reactivity and bleeding events following percutaneous coronary intervention and antiplatelet therapy: A post hoc analysis.

S. Saito, Takeshi Kimura, H. Ogawa, 2015, Thrombosis research.

Assessments of monitoring and risk stratification for the bleeding complication in the development of a new antiplatelet drug

M. Nishikawa, 2012 .

Regulation of myosin phosphatase through phosphorylation of the myosin-binding subunit in platelet activation.

K. Kaibuchi, H. Shiku, H. Wada, 1997, Blood.

Involvement of Ser/Thr Phosphatase on Tissue Factor Expression in Endothelial Cells

M. Nishikawa, S. Nagaya, 1997 .

PRASFIT-ACS: Prasugrel compared with clopidogrel For Japanese Patients with Acute Coronary Syndrome undergoing Percutaneous Coronary Intervention (PCI); PRASFIT-Elective: Prasugrel For Japanese patients with coronary artery diseases undergoing Elective PCI

S. Saito, H. Yokoi, S. Miyazaki, 2015 .

Efficacy and safety of rituximab in Japanese patients with relapsed chronic immune thrombocytopenia refractory to conventional therapy

Y. Miyakawa, Y. Ikeda, Y. Kanakura, 2015, International Journal of Hematology.

Possible Roles of Protein Ser/Thr Kinases/Phosphatases in Platelet Activation and Their Modulations by Selective Inhibitors

M. Nishikawa, 2000 .

Expressions of four major protein Ser/Thr phosphatases in human primary leukemic cells

M. Nagao, H. Shiku, S. Tamura, 1999, Leukemia.

Translocation of protein phosphatase 1 catalytic subunits during 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL-60 cells.

M. Mumby, M. Nagao, H. Shima, 1995, Cancer research.

Expression of the catalytic and regulatory subunits of protein phosphatase type 2A may be differentially modulated during retinoic acid-induced granulocytic differentiation of HL-60 cells.

M. Mumby, M. Nagao, B. Hemmings, 1994, Cancer research.

Pulsed High-dose Dexamethasone Therapy for Resistant, Chronic Adult Idiopathic Thrombocytopenic Purpura

T. Takubo, S. Nomura, Y. Kurata, 1996 .

Sarpogrelate hydrochloride, a serotonin 5HT2A receptor antagonist, ameliorates the development of chronic hypoxic pulmonary hypertension in rats

H. Sawada, K. Maruyama, Y. Mitani, 2015, Journal of Anesthesia.

Protein kinase C-catalyzed phosphorylation of an inhibitory phosphoprotein of myosin phosphatase is involved in human platelet secretion.

Y. Kataoka, H. Shiku, H. Wada, 2001, Blood.

Elevated levels of leukocyte tissue factor mRNA in patients with venous thromboembolism.

Y. Abe, T. Nakano, J. Nishioka, 2005, Thrombosis research.

Development of a New Method for Endovascular Aortic Repair: Combination Therapy of Cell Transplantation and Stent Grafts With a Drug Delivery System

H. Hirata, H. Shimpo, M. Kajimoto, 2006, Circulation.

Method of Cell Transplantation Promoting the Organization of Intraarterial Thrombus

A. Uchida, I. Yada, H. Hirata, 2005, Circulation.

Inhibition of shear stress-induced platelet aggregation by cilostazol, a specific inhibitor of cGMP-inhibited phosphodiesterase, in vitro and ex vivo.

Yasuo Ikeda, E. Imai, Y. Ikeda, 1997, Life sciences.

Cell-free system studies on the phosphorylation of the 17,000-20,000 dalton protein induced by phorbol ester in human leukemic cells and evidence for a similar event in virally transformed murine fibroblasts.

N. Feuerstein, M. Nishikawa, H. Cooper, 1985, Cancer research.

State-of-the-Art Review : Elevated Tissue Factor Levels in Leukemic Cell Homogenate

E. Gabazza, H. Shiku, H. Wada, 2000 .

Poor outcome in disseminated intravascular coagulation or thrombotic thrombocytopenic purpura patients with severe vascular endothelial cell injuries

H. Shiku, H. Wada, M. Ioka, 1998, American journal of hematology.

Inhibition of platelet aggregation by combined therapy with aspirin and cilostazol after off-pump coronary artery bypass surgery.

M. Okuda, H. Shimpo, T. Shimono, 2008, Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia.

Original Article Inhibition of Platelet Aggregation by Combined Therapy with Aspirin and Cilostazol after Off-Pump Coronary Artery Bypass Surgery

M. Okuda, H. Shimpo, T. Shimono, 2008 .

High plasma fibrinogen level is associated with poor clinical outcome in DIC patients

E. Gabazza, H. Shiku, T. Nobori, 2003, American journal of hematology.

Calyculin A and okadiac acid inhibit human platelet aggregation by blocking protein phosphatases types 1 and 2A.

T. Kuno, M. Nagao, H. Shima, 1994, Cellular signalling.

Low BCL-2 expression in acute leukemia with t(8;21) chromosomal abnormality

N. Kamada, N. Mahmud, M. Shikami, 1999, Leukemia.

Calyculin A retraction of mature megakaryocytes proplatelets from embryonic stem cells.

K. Eto, H. Wada, N. Katayama, 2008, Biochemical and biophysical research communications.

Stimulation of human platelet guanylate cyclase by nitroso compounds.

H. Hidaka, M. Nishikawa, T. Yamakado, 1982, Thrombosis research.

Inhibition of platelet aggregation by a novel coronary vasodilator, molsidomine and its metabolites

H. Hidaka, T. Endo, M. Fujiwara, 1982 .

Effects of Bisphosphonate Administration on the Bone Mass in Immune Thrombocytopenic Purpura Patients Under Treatment With Steroids

T. Takubo, Y. Tomiyama, K. Saigo, 2010, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

H. Hidaka, R. Adelstein, M. Naka, 1983, Nature.

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine(H-7), a potent inhibitor of protein kinases, inhibits the differentiation of HL-60 cells induced by phorbol diester.

H. Hidaka, S. Shirakawa, M. Nishikawa, 1986, Life sciences.

Characterization of the isoenzymes of cyclic nucleotide phosphodiesterase in human platelets and the effects of E4021.

H. Shiku, M. Ito, T. Nakano, 1996, Cellular signalling.

Forskolin potentiates G-CSF-induced proliferation of a murine myeloblastic leukemia cell line.

S. Shirakawa, M. Nishikawa, S. B. Omay, 1994, Leukemia research.

Augmentation of retinoic acid‐induced granulocytic differentiation in HL‐60 leukemia cells by serine/threonine protein phosphatase inhibitors

T. Kuno, C. Tanaka, M. Nagao, 1992, FEBS letters.

Possible involvement of calcineurin in retinoic acid-induced inhibition of leukemic HL-60 cell proliferation.

T. Kuno, H. Shiku, N. Katayama, 1998, International journal of oncology.

Shinsuke Nomura, K. Nakatani, T. Nobori, 2008, Thrombosis research.

Dephosphorylation of distinct sites on the 20 kDa myosin light chain by smooth muscle myosin phosphatase

D. Hartshorne, M. Ito, T. Nakano, 1999, FEBS letters.

Activity and antigen levels of thrombin-activatable fibrinolysis inhibitor in plasma of patients with disseminated intravascular coagulation.

E. Gabazza, H. Shiku, T. Nobori, 2001, Thrombosis research.

Elevated plasma levels of soluble platelet glycoprotein VI (GPVI) in patients with thrombotic microangiopathy.

M. Ikejiri, H. Wada, N. Katayama, 2014, Thrombosis research.

Changes in plasma tissue factor pathway inhibitor levels during the clinical course of disseminated intravascular coagulation

E. Gabazza, H. Shiku, H. Kato, 1998, Blood Coagulation and Fibrinolysis.

Increased truncated form of plasma tissue factor pathway inhibitor levels in patients with disseminated intravascular coagulation

E. Gabazza, H. Shiku, H. Wada, 1999, American journal of hematology/oncology.

Spa bathing activates fibrinolysis in patients with cerebral infarction.

H. Wada, S. Shirakawa, M. Nishikawa, 1993, Internal medicine.

Decreased tissue factor and tissue‐plasminogen activator antigen in relapsed acute promyelocytic leukemia

E. Gabazza, H. Shiku, H. Kato, 2000, American journal of hematology.

Ca2+ -calmodulin-dependent phosphorylation and platelet secretion

H. Hidaka, M. Nishikawa, Toshio Tanaka, 1980, Nature.

Inhibitory Phosphorylation Site for Rho-associated Kinase on Smooth Muscle Myosin Phosphatase*

D. Hartshorne, Jianhua Feng, M. Ito, 1999, The Journal of Biological Chemistry.

Phosphorylation of smooth muscle heavy meromyosin by calcium-activated, phospholipid-dependent protein kinase. The effect on actin-activated MgATPase activity.

H. Hidaka, R. Adelstein, M. Nishikawa, 1983, The Journal of biological chemistry.

Effect of Polymyxin B on platelet aggregation induced by arachidonate

H. Wada, S. Shirakawa, M. Nishikawa, 1988 .

Effects of Lipid Abnormalities on Arteriosclerosis and Hemostatic Markers in Patients under Hemodialysis

E. Gabazza, T. Nobori, H. Wada, 2003, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Expression of three major protein kinase C isozymes in various types of human leukemic cells.

H. Hidaka, S. Shirakawa, M. Nishikawa, 1991, Cancer research.

Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase.

Y Suzuki, S. Narumiya, H. Shiku, 1999, Blood.

Regulation of embryonic smooth muscle myosin by protein kinase C.

P. de Lanerolle, M. Nishikawa, 1988, The Journal of biological chemistry.

Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.

J. Sellers, H. Hidaka, R. Adelstein, 1984, The Journal of biological chemistry.

Plasma Levels of Total Plasminogen Activator Inhibitor-I (PAI-I) and tPA/PAI-1 Complex in Patients With Disseminated Intravascular Coagulation and Thrombotic Thrombocytopenic Purpura

E. Gabazza, H. Shiku, Y. Okugawa, 2001, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Atherosclerotic and Hemostatic Abnormalities in Patients Undergoing Hemodialysis

E. Gabazza, T. Nobori, H. Wada, 2003, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Hemostatic markers in Japanese patients undergoing anticoagulant therapy under thrombo-test monitoring.

J. Nishioka, E. Gabazza, H. Shiku, 1999, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

A role for calmodulin in the growth of human hematopoietic progenitor cells.

N. Katayama, S. Shirakawa, M. Nishikawa, 1990, Blood.

Putative involvement of protein kinase C in proliferation of human myeloid progenitor cells.

N. Katayama, S. Shirakawa, M. Nishikawa, 1989, Blood.

Increased serum levels of thrombopoietin in patients with thrombotic thrombocytopenic purpura, idiopathic thrombocytopenic purpura, or disseminated intravascular coagulation

H. Shiku, T. Kato, H. Wada, 1997, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The expression and possible roles of protein kinase C in haematopoietic cells.

S. Shirakawa, M. Nishikawa, 1992, Leukemia & lymphoma.

A role for protein kinase C in the growth of human erythroid progenitor cells.

N. Katayama, N. Shimizu, T. Sekine, 1992, Leukemia research.

Phosphorylation of smooth muscle myosin light chain kinase by protein kinase C. Comparative study of the phosphorylated sites.

R. Adelstein, S. Shirakawa, M. Nishikawa, 1985, The Journal of biological chemistry.

Role of calmodulin in platelet aggregation. Structure-activity relationship of calmodulin antagonists.

H. Hidaka, M. Nishikawa, 1982, The Journal of clinical investigation.

Increased thrombopoietin levels in idiopathic thrombocytopenic purpura patients with a poor response to steroid therapy.

H. Shiku, T. Kato, H. Wada, 1998, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Incidence of stroke, systemic embolism and bleeding events in patients without anticoagulation based on real-world data in Japan: a retrospective cohort study

M. Nishikawa, S. Tamaru, Akira Okada, 2022, BMJ Open.

DA-EPOCH-R combined with high-dose methotrexate in patients with newly diagnosed stage II-IV CD5-positive diffuse large B-cell lymphoma: a single-arm, open-label, phase 2 study.

K. Ohshima, Tomomi Yamada, T. Kinoshita, 2020, Haematologica.

Elevated soluble platelet glycoprotein VI is a useful marker for DVT in postoperative patients treated with edoxaban

A. Sudo, A. Uchida, K. Asanuma, 2014, International Journal of Hematology.

An adult case of acute lymphoblastic leukemia with necrotizing leukoencephalopathy.

N. Katayama, S. Shirakawa, T. Kobayashi, 1990, Japanese journal of medicine.

Increased plasma levels of tissue factor pathway inhibitor‐activated factor X complex in patients with disseminated intravascular coagulation

E. Gabazza, H. Shiku, Y. Okugawa, 2000, American journal of hematology.

Inhibition of platelet aggregation by the cAMP-phosphodiesterase inhibitor, cilostamide, may not be associated with activation of cAMP-dependent protein kinase.

S. Shirakawa, M. Nishikawa, K. Deguchi, 1992, Cellular signalling.

A new system to detect native microaggregates of platelets in vivo, with a novel platelet aggregometer employing laser light scattering.

H. Hidaka, S. Iino, M. Nishikawa, 1998, Thrombosis research.

[Spontaneous transient remission in adult acute myeloid leukemia].

N. Katayama, S. Shirakawa, T. Kobayashi, 1989, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Differential Association of Protein Ser/Thr Phosphatase Types 1 and 2A with the Cytoskeleton upon Platelet Activation

H. Shima, H. Shiku, M. Nishikawa, 1996, Thrombosis and Haemostasis.

Inhibition by combined therapy with ticlopidine and aspirin of enhanced platelet aggregation during physical exercise in patients with coronary artery disease.

T. Nakano, T. Tanigawa, Y. Ikeda, 2001, American heart journal.

Cardiovascular events occur independently of high on-aspirin platelet reactivity and residual COX-1 activity in stable cardiovascular patients

K. Kario, N. Yonemoto, K. Kitagawa, 2016, Thrombosis and Haemostasis.

Novel acoustic evaluation system for scratching behavior in itching dermatitis: Rapid and accurate analysis for nocturnal scratching of atopic dermatitis patients

Hitoshi Mizutani, Tomomi Yamada, Yuichi Noro, 2014, The Journal of dermatology.

Safety and Efficacy of Prasugrel in Elderly/Low Body Weight Japanese Patients with Ischemic Stroke: Randomized PRASTRO-II

A. Ogawa, K. Kitagawa, T. Kitazono, 2020, Cerebrovascular Diseases.

Increased platelet aggregability in response to shear stress in acute myocardial infarction and its inhibition by combined therapy with aspirin and cilostazol after coronary intervention.

T. Nakano, T. Tanigawa, Y. Ikeda, 2000, The American journal of cardiology.

Effect of combination therapy of ezetimibe and rosuvastatin on regression of coronary atherosclerosis in patients with coronary artery disease.

Tomomi Yamada, T. Tanigawa, Masaaki Ito, 2015, International heart journal.

Decreased expression of type II protein kinase C in HL-60 variant cells resistant to induction of cell differentiation by phorbol diester.

H. Hidaka, S. Shirakawa, M. Nishikawa, 1990, Cancer research.

Influence of cytochrome P450 polymorphisms on the antiplatelet effects of prasugrel in patients with non-cardioembolic stroke previously treated with clopidogrel

A. Ogawa, T. Kitazono, Y. Ikeda, 2018, Journal of Thrombosis and Thrombolysis.

[Acute myelogenous leukemia (M4) occurring during chronic lymphocytic leukemia].

H. Shiku, H. Suzuki, K. Kita, 1997, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Increased Soluble Fibrin in Plasma of Patients with Disseminated Intravascular Coagulation

E. Gabazza, H. Shiku, K. Nakatani, 2003, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Good or Poor Responses of Hemostatic Molecular Markers in Patients with Hematopoietic Disorders After Treatment of Disseminated Intravascular Coagulation

E. Gabazza, H. Shiku, Y. Okugawa, 2003, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Diagnosis of Disseminated Intravascular Coagulation by Hemostatic Molecular Markers

E. Gabazza, H. Shiku, H. Wada, 2000, Seminars in thrombosis and hemostasis.

Elevated Plasma Levels of Fibrin Degradation Productsby Granulocyte-Derived Elastase in Patients with Disseminated Intravascular Coagulation

H. Shiku, K. Nakatani, K. Onishi, 2005 .

Phosphorylation of phospholamban by calcium-activated, phospholipid-dependent protein kinase. Stimulation of cardiac sarcoplasmic reticulum calcium uptake.

R. Adelstein, M. Movsesian, M. Nishikawa, 1984, The Journal of biological chemistry.

Inhibition of platelet aggregation and stimulation of guanylate cyclase by an antianginal agent molsidomine and its metabolites.

H. Hidaka, M. Nishikawa, M. Kanamori, 1982, The Journal of pharmacology and experimental therapeutics.

Blood Pressure Level and Variability During Long-Term Prasugrel or Clopidogrel Medication After Stroke

A. Ogawa, K. Kitagawa, T. Kitazono, 2021, Stroke.

Rho-kinase induces association of adducin with the cytoskeleton in platelet activation.

K. Kaibuchi, H. Shiku, M. Nishikawa, 2005, Biochemical and biophysical research communications.

Pharmacologic platelet anesthesia by glycoprotein IIb/IIIa complex antagonist and argatroban during in vitro extracorporeal circulation.

H. Shiku, I. Yada, H. Shimpo, 2003, The Journal of thoracic and cardiovascular surgery.

A Heparin-coated Circuit Maintains Platelet Aggregability in Response to Shear Stress in an In Vitro Model of Cardiopulmonary Bypass

Y. Ikeda, H. Shiku, I. Yada, 1998, Thrombosis and Haemostasis.

and argatroban during in vitro extracorporeal circulation Pharmacologic platelet anesthesia by glycoprotein IIb/IIIa complex antagonist

H. Shiku, I. Yada, T. Shimono, 2013 .

Comparison of prasugrel and clopidogrel in patients with non-cardioembolic ischaemic stroke: a phase 3, randomised, non-inferiority trial (PRASTRO-I)

A. Ogawa, K. Kitagawa, T. Kitazono, 2019, The Lancet Neurology.

Possible involvement of direct stimulation of protein kinase C by unsaturated fatty acids in platelet activation.

H. Hidaka, S. Shirakawa, M. Nishikawa, 1988, Biochemical pharmacology.

Purification and characterization of Ca2+·phospholipid dependent protein kinase (C kinase) from human platelets

H. Hidaka, R. Adelstein, S. Shirakawa, 1985 .

Echocardiographic Assessment of Cardiac Structural and Functional Abnormalities in Patients With End-Stage Renal Disease Receiving Chronic Hemodialysis.

Tomomi Yamada, H. Matsuo, Tomohiro Murata, 2017, Circulation journal : official journal of the Japanese Circulation Society.

A noninferiority confirmatory trial of prasugrel versus clopidogrel in Japanese patients with non-cardioembolic stroke: rationale and study design for a randomized controlled trial – PRASTRO-I trial

A. Ogawa, K. Kitagawa, T. Kitazono, 2018, Expert opinion on pharmacotherapy.

Efficacy and Safety of Prasugrel by Stroke Subtype: A Sub-Analysis of the PRASTRO-I Randomized Controlled Trial

A. Ogawa, K. Kitagawa, T. Kitazono, 2020, Journal of atherosclerosis and thrombosis.

Direct stimulation of protein kinase C by arachidonate is associated with platelet activation

H. Wada, S. Shirakawa, M. Nishikawa, 1987 .

Optimal duration of dual antiplatelet therapy following treatment with the endeavor zotarolimus‐eluting stent in real‐world Japanese patients with coronary artery disease (OPERA): Study design and rationale

A. Hirayama, S. Morita, Masato Nakamura, 2014, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

Decreased expression of protein phosphatase type 2A in HL-60 variant (HL-60RAr) cells resistant to induction of cell differentiation by all-trans retinoic acid.

M. Nagao, H. Shima, H. Shiku, 1995, Experimental hematology.

Adult respiratory distress syndrome complicating hematological diseases

H. Wada, N. Katayama, K. Kita, 1993, European journal of haematology.

Dose-adjusted (DA)-EPOCH-R with high-dose methotrexate (HD-MTX) for newly diagnosed stage II-IV CD5-positive diffuse large B-cell Iymphoma (CD5+ DLBCL): Primary analysis of PEARL5 study.

K. Ohshima, Tomomi Yamada, T. Kinoshita, 2018 .

TADAFER II: Tadalafil treatment for fetal growth restriction - a study protocol for a multicenter randomised controlled phase II trial

T. Ikeda, A. Sekizawa, Hiroaki Tanaka, 2018, BMJ Open.

[High shear stress induced platelet aggregation (h-SIPA) and effects of antiplatelet therapy].

T. Nakano, T. Tanigawa, N. Isaka, 1998, Nihon rinsho. Japanese journal of clinical medicine.

Antialbuminuric effect of eplerenone in comparison to thiazide diuretics in patients with hypertension

Tomomi Yamada, T. Kitamura, Masaaki Ito, 2017, Journal of clinical hypertension.

Fibrinolysis in patients with lupus anticoagulant

H. Wada, S. Shirakawa, M. Nishikawa, 1986 .

Shear stress-induced myosin association with cytoskeleton and phosphorylation in human platelets.

Y. Ikeda, H. Shiku, T. Hayashi, 1997, Life sciences.

Selective inhibitors of calmodulin-dependent phosphodiesterase and other enzymes.

H. Hidaka, M. Inagaki, M. Nishikawa, 1988, Methods in enzymology.

Prognostic Impact of Aortic Calcification Index and Ankle-Arm Blood Pressure Indexin Patients under Hemodialysis

E. Gabazza, H. Shiku, T. Nobori, 2005, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Comparative studies of glycoprotein Ib in heparin coated and nonheparin coated extracorporeal circulation circuits.

Y. Shomura, I. Yada, B. P. Cruz, 1998, ASAIO journal.

Pharmacological properties of platelet strips.

H. Hidaka, M. Nishikawa, T. Yamakado, 1983, European journal of pharmacology.

[Studies on C1 inactivator resistant fibrinolytic activity].

H. Wada, M. Tanigawa, S. Tamaki, 1991, Rinsho byori. The Japanese journal of clinical pathology.