C. Pilbeam

发表

Prostaglandin E2 as a Therapeutic Target in Bladder Cancer: From Basic Science to Clinical Trials.

John A. Taylor, B. Woolbright, C. Pilbeam, 2020, Prostaglandins & other lipid mediators.

Prostaglandin-mediated inhibition of PTH-stimulated β-catenin signaling in osteoblasts by bone marrow macrophages.

C. Pilbeam, Thomas Estus, S. Choudhary, 2016, Bone.

Extracellular Calcium Is a Potent Inducer of Cyclo‐oxygenase‐2 in Murine Osteoblasts Through an ERK Signaling Pathway

S. Wadhwa, L. Raisz, C. Pilbeam, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Inhibition by 17 beta-estradiol of PTH stimulated resorption and prostaglandin production in cultured neonatal mouse calvariae.

J. Klein-Nulend, L. Raisz, C. Pilbeam, 1989, Biochemical and biophysical research communications.

Overexpression of COX-2 in human osteosarcoma cells decreases proliferation and increases apoptosis.

M. Hansen, H. Herschman, O. Voznesensky, 2006, Cancer research.

Deep‐earthquake initiation by phase transformations

J. Vaisnys, C. Pilbeam, 1976 .

R. Breyer, C. Kennedy, L. Raisz, 2022 .

Effects of selective prostaglandin EP4 receptor antagonist on osteoclast formation and bone resorption in vitro.

R. Young, Xiaodong Li, L. Raisz, 2002, Bone.

Involvement of CCAAT Enhancer Binding Protein Transcription Factors in the Regulation of Prostaglandin G/H Synthase 2 Expression by Interleukin‐1 in Osteoblastic MC3T3‐E1 Cells

C. Pilbeam, J. Harrison, P. L. Kelly, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The short term effects of tamoxifen on bone turnover in older women.

A. Kenny, L. Raisz, K. Prestwood, 1995, The Journal of clinical endocrinology and metabolism.

Regulation of Fibroblast Growth Factor 2 and Fibroblast Growth Factor Receptors by Transforming Growth Factor β in Human Osteoblastic MG‐63 Cells

M. Hurley, A. Hand, R. Florkiewicz, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Prostaglandin E2 acts via bone marrow macrophages to block PTH-stimulated osteoblast differentiation in vitro

O. Voznesensky, C. Pilbeam, S. Choudhary, 2013, Bone.

Low dose estrogen and calcium have an additive effect on bone resorption in older women.

D. Thompson, M. Seibel, A. Kenny, 1999, The Journal of clinical endocrinology and metabolism.

Randomized double-blind placebo-controlled trial of celecoxib for oral mucositis in patients receiving radiation therapy for head and neck cancer.

R. Feinn, A. Salner, U. Hegde, 2014, Oral oncology.

Role of cyclooxygenase-2 in bone resorption.

Yoshiya Tanaka, L. Raisz, Y. Okada, 2003, Journal of UOEH.

The effect of a short course of calcium and vitamin d on bone turnover in older women

A. Kenny, L. Raisz, K. Prestwood, 2005, Osteoporosis International.

The short-term effects of conjugated estrogen on bone turnover in older women.

P. Delmas, L. Deftos, J. Burleson, 1994, The Journal of clinical endocrinology and metabolism.

Prostaglandins: Mechanisms of action and regulation of production in bone

L. Raisz, C. Pilbeam, P. Fall, 2005, Osteoporosis International.

Basal bone phenotype and increased anabolic responses to intermittent parathyroid hormone in healthy male COX-2 knockout mice.

Q. Gao, D. Goltzman, Manshan Xu, 2010, Bone.

Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice.

Q. Gao, C. Hao, M. Breyer, 2009, Bone.

Do cyclooxygenase-2 knockout mice have primary hyperparathyroidism?

D. Goltzman, G. Gronowicz, Manshan Xu, 2005, Endocrinology.

Role of the prostaglandin pathway and the use of NSAIDs in genitourinary malignancies

A. Nisbet, C. Pilbeam, John A. Taylor III, 2008, Expert review of anticancer therapy.

Lack of evidence for an increase in interleukin‐6 expression in adult murine bone, bone marrow, and marrow stromal cell cultures after ovariectomy

L. Raisz, J. Kalinowski, C. Pilbeam, 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae.

H. Kawaguchi, L. Raisz, C. Pilbeam, 1995, The Journal of clinical investigation.

Anabolic effects of 3,3',5-triiodothyronine and triiodothyroacetic acid in cultured neonatal mouse parietal bones.

H. Kawaguchi, L. Raisz, C. Pilbeam, 1994, Endocrinology.

The effect of deletion of cyclooxygenase-2, prostaglandin receptor EP2, or EP4 in bone marrow cells on osteoclasts induced by mouse mammary cancer cell lines.

N. Kugai, L. Raisz, T. Akatsu, 2003, Bone.

Identification of multiple cis‐acting elements mediating the induction of prostaglandin G/H synthase‐2 by phorbol ester in murine osteoblastic cells

H. Herschman, O. Voznesensky, C. Pilbeam, 2000, Journal of cellular biochemistry.

Production of both 92- and 72-kDa gelatinases by bone cells.

J. Kalinowski, C. Pilbeam, J. Lorenzo, 1992, Matrix.

Prostaglandins in bone: bad cop, good cop?

L. Raisz, C. Pilbeam, K. Blackwell, 2010, Trends in Endocrinology & Metabolism.

Regulation of the prostaglandin pathway during development of invasive bladder cancer in mice.

G. Kuchel, John A. Taylor, B. Ristau, 2009, Prostaglandins & other lipid mediators.

Null mutation for Macrophage Migration Inhibitory Factor (MIF) is associated with less aggressive bladder cancer in mice

G. Kuchel, L. Leng, R. Bucala, 2007, BMC Cancer.

Cyclooxygenase-2 gene disruption promotes proliferation of murine calvarial osteoblasts in vitro.

L. Raisz, O. Voznesensky, C. Pilbeam, 2007, Bone.

Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture.

S. Morham, L. Raisz, C. Pilbeam, 2000, The Journal of clinical investigation.

Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor.

M. Hurley, H. Herschman, H. Kawaguchi, 1995, The Journal of clinical investigation.

Regulation of the two prostaglandin G/H synthases by parathyroid hormone, interleukin-1, cortisol, and prostaglandin E2 in cultured neonatal mouse calvariae.

H. Kawaguchi, L. Raisz, O. Voznesensky, 1994, Endocrinology.

Stimulation of prostaglandin e2 production by interleukin‐1α and transforming growth factor α in osteoblastic MC3T3‐E1 cells

H. Kawaguchi, L. Raisz, C. Pilbeam, 1994 .

Prostaglandins and Bone.

C. Pilbeam, 2019, Handbook of experimental pharmacology.

Effect of 1,25‐dihydroxyvitamin D3 on prostaglandin E2 production in cultured mouse parietal bones

J. Klein-Nulend, L. Raisz, C. Pilbeam, 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Effects of androgens on parathyroid hormone and interleukin‐1‐stimulated prostaglandin production in cultured neonatal mouse calvariae

L. Raisz, C. Pilbeam, 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3',5'-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells.

H. Herschman, S. Tetradis, B. Kream, 1997, Endocrinology.

Autoregulation of inducible prostaglandin G/H synthase in osteoblastic cells by prostaglandins

L. Raisz, O. Voznesensky, C. Pilbeam, 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Measurement of interleukin-1 stimulated constitutive prostaglandin G/H synthase (cyclooxygenase) mRNA levels in osteoblastic MC3T3-E1 cells using competitive reverse transcriptase polymerase chain reaction.

D. Rowe, H. Kawaguchi, R. Yavari, 1994, Endocrine research.

Regulation of Prostaglandin G/H Synthase‐2 Expression by Interleukin‐1 in Human Osteoblast‐like Cells

Y. Min, L. Raisz, C. Pilbeam, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mice lacking the type I interleukin-1 receptor do not lose bone mass after ovariectomy.

G. Gronowicz, J. Kalinowski, M. Glaccum, 1998, Endocrinology.

Effects of prostaglandin E2 on bone in mice in vivo.

Q. Gao, Manshan Xu, L. Raisz, 2009, Prostaglandins & other lipid mediators.

Anabolic effects of PTH in cyclooxygenase-2 knockout osteoblasts in vitro.

L. Raisz, C. Pilbeam, H. Huang, 2008, Biochemical and biophysical research communications.

Prostaglandin receptor EP2 mediates PGE2 stimulated hypercalcemia in mice in vivo.

R. Breyer, Xiaodong Li, L. Raisz, 2002, Prostaglandins & other lipid mediators.

Transforming growth factor-beta1 regulation of prostaglandin G/H synthase-2 expression in osteoblastic MC3T3-E1 cells.

H. Herschman, H. Kawaguchi, L. Raisz, 1997, Endocrinology.

Transforming growth factor-beta1 regulation of prostaglandin G/H synthase-2 expression in osteoblastic MC3T3-E1 cells.

H. Herschman, H. Kawaguchi, L. Raisz, 1997, Endocrinology.

Interleukin‐4 inhibits prostaglandin G/H synthase‐2 and cytosolic phospholipase A2 induction in neonatal mouse parietal bone cultures

L. Raisz, O. Voznesensky, C. Pilbeam, 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Anabolic Effects of Progesterone on Fetal Rat Calvaria in Tissue Culture

L. Raisz, C. Pilbeam, D. Manzi, 1994, The Journal of the Society for Gynecologic Investigation: JSGI.

Intact insulin‐like growth factor binding protein‐5 (IGFBP‐5) associates with bone matrix and the soluble fragments of IGFBP‐5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2‐treatment

S. Mohan, M. Hurley, M. Kumegawa, 1996, Journal of cellular physiology.

Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-stimulated cAMP Signaling in Murine Osteoblasts*

H. Aguila, C. Pilbeam, J. Lorenzo, 2015, The Journal of Biological Chemistry.

Bone Morphogenetic Protein 2 Induces Cyclo‐oxygenase 2 in Osteoblasts via a Cbfa1 Binding Site: Role in Effects of Bone Morphogenetic Protein 2 In Vitro and In Vivo

H. Herschman, H. Kawaguchi, V. Katavic, 2005 .

Bone Morphogenetic Protein 2 Induces Cyclo‐oxygenase 2 in Osteoblasts via a Cbfa1 Binding Site: Role in Effects of Bone Morphogenetic Protein 2 In Vitro and In Vivo

H. Herschman, H. Kawaguchi, V. Katavic, 2002 .

Parathyroid Hormone Induction of Cyclooxygenase-2 in Murine Osteoblasts: Role of the Calcium-Calcineurin-NFAT Pathway

H. Drissi, H. Herschman, B. Kream, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The role of prostaglandins in the regulation of bone metabolism.

H. Kawaguchi, L. Raisz, C. Pilbeam, 1995, Clinical orthopaedics and related research.

LOW DOSE ESTROGEN AND CALCIUM HAVE AN ADDITIVE EFFECT ON BONE RESORPTION IN OLDER WOMEN

D. Thompson, M. Seibel, A. Kenny, 1999 .

Comparison of the effects of 3,5,3′‐triiodothyroacetic acid and triiodothyronine on bone resorption in cultured fetal rat long bones and neonatal mouse calvariae

H. Kawaguchi, L. Raisz, C. Pilbeam, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Take two aspirin: for osteoporosis?

L. Raisz, C. Pilbeam, K. Blackwell, 2008 .

Cyclooxygenase-2 Suppresses the Anabolic Response to PTH Infusion in Mice

E. Canalis, D. Adams, C. Pilbeam, 2015, PloS one.

Effect of deletion of the prostaglandin EP4 receptor on stimulation of calcium release from cultured mouse calvariae: impaired responsiveness in heterozygotes.

M. Breyer, Y. Guan, L. Raisz, 2005, Prostaglandins & other lipid mediators.

Prostaglandins and bone metabolism

L. Raisz, C. Pilbeam, S. Choudhary, 2020, Principles of Bone Biology.

Chapter 54 – Prostaglandins and Bone Metabolism

L. Raisz, C. Pilbeam, J. Harrison, 2002 .

H. Kawaguchi, Y. Koishihara, Y. Ohsugi, 2022 .

Continuous PTH in Male Mice Causes Bone Loss Because It Induces Serum Amyloid A.

A. Mazzocca, D. Adams, M. Mccarthy, 2018, Endocrinology.

Strontium Ranelate Promotes Osteoblastic Differentiation and Mineralization of Murine Bone Marrow Stromal Cells: Involvement of Prostaglandins

P. Halbout, L. Raisz, Shilpa Choudhary, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells.

H. Kawaguchi, L. Raisz, O. Voznesensky, 1993, The Journal of biological chemistry.

Macrophage migratory inhibitory factor promotes bladder cancer progression via increasing proliferation and angiogenesis.

John A. Taylor, D. Choudhary, T. Sielecki, 2013, Carcinogenesis.

For Peer Review Macrophage Migratory Inhibitory Factor (MIF) promotes bladder cancer progression via increasing proliferation and angiogenesis

John A. Taylor, C. Pilbeam, K. Scarpato, 2013 .

Prostaglandins, Leukotrienes and Bone

L. Raisz, C. Pilbeam, 2004 .

Role of the cyclooxygenase pathway in chemotherapy-induced oral mucositis: a pilot study

S. Sonis, D. Peterson, R. Lalla, 2009, Supportive Care in Cancer.

The Role of Pyruvate Dehydrogenase Kinase-4 (PDK4) in Bladder Cancer and Chemoresistance

John A. Taylor, D. Choudhary, Erika Abbott, 2018, Molecular Cancer Therapeutics.

Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts

V. Rodionov, T. Yin, Yi I. Wu, 2017, Nature Communications.

Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons

Jingxue Shi, J. Hewett, S. Hewett, 2016, The Journal of Biological Chemistry.

Null mutation in macrophage migration inhibitory factor prevents muscle cell loss and fibrosis in partial bladder outlet obstruction.

G. Kuchel, L. Leng, R. Bucala, 2006, American journal of physiology. Renal physiology.

Extracellular calcium induces COX-2 in osteoblasts via a PKA pathway.

Ashok Kumar, L. Raisz, R. Kale, 2004, Biochemical and biophysical research communications.

Fluid flow induces COX-2 expression in MC3T3-E1 osteoblasts via a PKA signaling pathway.

Sunil Wadhwa, S. Wadhwa, L. Raisz, 2002, Biochemical and biophysical research communications.

Effects and regulation of prostaglandins in bone: Possible implications for the pathogenesis of osteoporosis

J. Klein-Nulend, L. Raisz, C. Pilbeam, 1991, Journal of Bone and Mineral Metabolism.

Biphasic Effect of Prostaglandin E2 on Osteoclast Formation in Spleen Cell Cultures: Role of the EP2 Receptor

N. Kugai, L. Raisz, T. Akatsu, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

SATB1 and bladder cancer: Is there a functional link?

John A. Taylor, D. Choudhary, B. Woolbright, 2017, Urologic oncology.

Increased expression of L-selectin (CD62L) in high-grade urothelial carcinoma: A potential marker for metastatic disease.

K. Claffey, John A. Taylor, D. Choudhary, 2015, Urologic oncology.

Effects of prostaglandin E2 and lipopolysaccharide on osteoclastogenesis in RAW 264.7 cells.

U. Lerner, L. Raisz, C. Pilbeam, 2007, Prostaglandins, leukotrienes, and essential fatty acids.

Pulsating Fluid Flow Stimulates Prostaglandin Release and Inducible Prostaglandin G/H Synthase mRNA Expression in Primary Mouse Bone Cells

E H Burger, J. Klein-Nulend, E. Burger, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Measurement of muscle disease by quantitative second-harmonic generation imaging.

William A Mohler, Douglas J Adams, Robert P Dougherty, 2008, Journal of biomedical optics.

Differential regulation of platelet‐derived growth factor stimulated migration and proliferation in osteoblastic cells

S. Krane, C. Pilbeam, M. Mehrotra, 2004, Journal of cellular biochemistry.

Molecular cloning and expression of a rat prostaglandin E2 receptor of the EP2 subtype.

L. Raisz, C. Pilbeam, K. Nemoto, 1997, Prostaglandins.

Mechanical Properties of Granular Media

C. Pilbeam, Andrius Vaišnys, 1975 .

Stimulation of cAMP production and cyclooxygenase-2 by prostaglandin E(2) and selective prostaglandin receptor agonists in murine osteoblastic cells.

Hiroshi Kawaguchi, Daichi Chikazu, Yoko Sakuma, 2004, Bone.

Fracture incidence in postmenopausal women with primary hyperparathyroidism.

H. Crombie, A. Kenny, L. Raisz, 1995, Surgery.

Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice.

R. Breyer, L. Raisz, C. Pilbeam, 2002, Bone.

Bone morphogenetic protein 2 enhances PGE(2)-stimulated osteoclast formation in murine bone marrow cultures.

P. Hortschansky, L. Raisz, C. Pilbeam, 2009, Prostaglandins & other lipid mediators.

Fluid flow induces Rankl expression in primary murine calvarial osteoblasts

Sunil Wadhwa, S. Wadhwa, O. Voznesensky, 2006, Journal of cellular biochemistry.

Bone morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfal binding site: role in effects of bone morphogenetic protein 2 in vitro and in vivo.

H. Herschman, H. Kawaguchi, Manshan Xu, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Effect of deletion of the prostaglandin EP2 receptor on the anabolic response to prostaglandin E2 and a selective EP2 receptor agonist.

Q. Gao, Qi Gao, L. Raisz, 2008, Prostaglandins & other lipid mediators.

Role of Cbfa1/Runx2 in the fluid shear stress induction of COX-2 in osteoblasts.

O. Voznesensky, C. Pilbeam, M. Mehrotra, 2006, Biochemical and biophysical research communications.

Neuropeptide Y is expressed by osteocytes and can inhibit osteoblastic activity

Xi Jiang, I. Kalajzic, P. Baldock, 2009, Journal of cellular biochemistry.

CHAPTER 26 – Mechanotransduction of Orthodontic Forces

R. Nanda, S. Wadhwa, C. Pilbeam, 2010 .

Contact thermal conductivity in lunar aggregates.

J. Vaisnys, C. Pilbeam, 1973 .

Fluid Flow Induction of Cyclo‐Oxygenase 2 Gene Expression in Osteoblasts Is Dependent on an Extracellular Signal‐Regulated Kinase Signaling Pathway

Sunil Wadhwa, S. Wadhwa, L. Raisz, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Acoustic velocities and energy losses in granular aggregates

J. Vaisnys, C. Pilbeam, 1973 .

Prostaglandins and Other Lipid Mediators Effects of prostaglandin E 2 on bone in mice in vivo

Q. Gao, Manshan Xu, L. Raisz, 2009 .

Differential Effects of Nonsteroidal Anti‐Inflammatory Drugs on Constitutive and Inducible Prostaglandin G/H Synthase in Cultured Bone Cells

L. Raisz, C. Pilbeam, C. Alander, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Expression and regulation of prostaglandin F receptor mRNA in rodent osteoblastic cells.

L. Raisz, C. Pilbeam, K. Nemoto, 1995, Prostaglandins.

Mechanism of regulation of prostaglandin production by parathyroid hormone, interleukin-1, and cortisol in cultured mouse parietal bones.

J. Klein-Nulend, L. Raisz, C. Pilbeam, 1991, Endocrinology.

Cell-to-Cell adhesion via intercellular adhesion molecule-1 and leukocyte function-associated antigen-1 pathway is involved in 1alpha,25(OH)2D3, PTH and IL-1alpha-induced osteoclast differentiation and bone resorption.

Kenichi Watanabe, Yoshiya Tanaka, S. Eto, 2002, Endocrine journal.

Stimulation of prostaglandin E2 production by interleukin-1 alpha and transforming growth factor alpha in osteoblastic MC3T3-E1 cells.

H. Kawaguchi, L. Raisz, C. Pilbeam, 1994, Journal of Bone and Mineral Research.

Parathyroid hormone induces prostaglandin G/H synthase-2 expression by a cyclic adenosine 3',5'-monophosphate-mediated pathway in the murine osteoblastic cell line MC3T3-E1.

S. Tetradis, B. Kream, C. Pilbeam, 1996, Endocrinology.

Transcriptional induction of cyclooxygenase-2 in osteoblasts is involved in interleukin-6-induced osteoclast formation.

C. Miyaura, Y. Koishihara, L. Raisz, 1997, Endocrinology.