D. Hurst

发表

Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain.

A. Naylor, W. Winchester, A. Hall, 2009, Bioorganic & medicinal chemistry letters.

Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.

David M. Wilson, D. Pemberton, Frank T. Coppo, 2012, Bioorganic & medicinal chemistry letters.

Discovery of sodium 6-[(5-chloro-2-{[(4-chloro-2-fluorophenyl)methyl]oxy}phenyl)methyl]-2-pyridinecarboxylate (GSK269984A) an EP(1) receptor antagonist for the treatment of inflammatory pain.

A. Naylor, W. Winchester, A. Hall, 2009, Bioorganic & medicinal chemistry letters.

Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy.

A. Naylor, A. Hall, A. Billinton, 2008, Bioorganic & medicinal chemistry letters.

Discovery of novel biaryl heterocyclic EP1 receptor antagonists.

I. Chessell, A. Naylor, X. Lewell, 2006, Bioorganic & medicinal chemistry letters.

Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping.

A. Naylor, P. Theobald, A. Hall, 2008, Bioorganic & medicinal chemistry letters.

Beta 1-selective adrenoceptor antagonists. 3. 4-Azolyl-linked phenoxypropanolamines.

P. Machin, D. Hurst, L. Blaber, 1984, Journal of medicinal chemistry.

β1‐SELECTIVE ADRENOCEPTOR ANTAGONISTS. 3. 4‐AZOLYL LINKED PHENOXYPROPANOLAMINES

P. Machin, D. Hurst, L. Blaber, 1984 .

The Design and Synthesis of Potent Inhibitors of Hepatitis C Virus NS3–4A Proteinase

N. Jennings, F. Wilson, M. Carr, 1999, Antiviral chemistry & chemotherapy.

Beta-adrenoceptor activity of the stereoisomers of the bufuralol alcohol and ketone metabolites.

P. Machin, P J Machin, D N Hurst, 1985, Journal of medicinal chemistry.

The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.

I. Chessell, A. Naylor, A. Hall, 2007, Bioorganic & medicinal chemistry letters.

Optimization of sphingosine-1-phosphate-1 receptor agonists: effects of acidic, basic, and zwitterionic chemotypes on pharmacokinetic and pharmacodynamic profiles.

I. Wall, K. Philpott, T. Heightman, 2014, Journal of medicinal chemistry.

β-Adrenoceptor Activity of the Stereoisomers of the Bufuralol Alcohol and Ketone Metabolites.

P. Machin, D. Hurst, J. M. Osbond, 1986 .

Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists.

A. Naylor, P. Theobald, A. Hall, 2011, Bioorganic & medicinal chemistry letters.

The identification of α-ketoamides as potent inhibitors of hepatitis c virus nS3-4a proteinase

N. Jennings, F. Wilson, P. Jones, 2001 .