Xukai Jiang

发表

Three glycoside hydrolase family 12 enzymes display diversity in substrate specificities and synergistic action between each other

Lushan Wang, Y. Qu, Jingyao Qu, 2019, Molecular Biology Reports.

Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance

F. Schreiber, T. Lithgow, Lushan Wang, 2020, Advanced science.

Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity

J. Li, H. Coleman, H. Parkington, 2022, Cellular and Molecular Life Sciences.

Converting a β-N-acetylhexosaminidase into two trans-β-N-acetylhexosaminidases by domain-targeted mutagenesis

G. Gu, Fengshan Wang, Lili Lu, 2019, Applied Microbiology and Biotechnology.

Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane

Lushan Wang, T. Velkov, Bing Yuan, 2021, Computational and structural biotechnology journal.

Interactions between polymyxin B and various bacterial membrane mimics: A molecular dynamics study.

Bing Yuan, Kai Yang, Xukai Jiang, 2021, Colloids and surfaces. B, Biointerfaces.

Simulations of octapeptin–outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency

F. Schreiber, J. Li, Lushan Wang, 2020, Journal of Biological Chemistry.

Outer Membranes of Polymyxin-Resistant Acinetobacter baumannii with Phosphoethanolamine-modified Lipid A and Lipopolysaccharide Loss Display Different Atomic-Scale Interactions with Polymyxins.

F. Schreiber, J. Li, Lushan Wang, 2020, ACS infectious diseases.

A Novel β-Glucosidase From Chryseobacterium scophthalmum 1433 for Efficient Rubusoside Production From Stevioside

Xiao Yang, M. Xiao, Li Xu, 2021, Frontiers in Microbiology.

Antimicrobial Peptides: An Update on Classifications and Databases

Yan Zhu, Xukai Jiang, Ahmer Bin Hafeez, 2021, International journal of molecular sciences.

Biophysical Impact of Lipid A Modification Caused by Mobile Colistin Resistance Gene on Bacterial Outer Membranes.

Bing Yuan, Jian Li, Zhihong Zhang, 2021, The journal of physical chemistry letters.

Docking-guided rational engineering of a macrolide glycosyltransferase glycodiversifies epothilone B

Zheng Zhang, Yue-zhong Li, Peng Zhang, 2022, Communications biology.

Novel dTDP-l-Rhamnose Synthetic Enzymes (RmlABCD) From Saccharothrix syringae CGMCC 4.1716 for One-Pot Four-Enzyme Synthesis of dTDP-l-Rhamnose

G. Gu, X. An, M. Xiao, 2021, Frontiers in Microbiology.

Biochemical characterization of a new β-glucosidase (Cel3E) from Penicillium piceum and its application in boosting lignocelluloses bioconversion and forming disaccharide inducers: New insights into the role of β-glucosidase

Lushan Wang, Dongyuan Zhang, Le Gao, 2014 .

Converting a β-N-acetylhexosaminidase into two trans-β-N-acetylhexosaminidases by domain-targeted mutagenesis

G. Gu, Fengshan Wang, Lili Lu, 2019, Applied Microbiology and Biotechnology.

Enhancement in catalytic activity of Aspergillus niger XynB by selective site-directed mutagenesis of active site amino acids

Lushan Wang, Xukai Jiang, Xiuyun Wu, 2017, Applied Microbiology and Biotechnology.

Molecular dynamics simulations informed by membrane lipidomics reveal the structure-interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii.

F. Schreiber, R. Hancock, J. Li, 2020, The Journal of antimicrobial chemotherapy.

Structure-Interaction Relationship of Polymyxins with the Membrane of Human Kidney Proximal Tubular Cells.

J. Li, Lushan Wang, Jingliang Li, 2020, ACS infectious diseases.

Substrate binding interferes with active site conformational dynamics in endoglucanase Cel5A from Thermobifida fusca.

Guanjun Chen, Lushan Wang, Limei Xu, 2017, Biochemical and biophysical research communications.

A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

N. Voelcker, J. Li, R. Nation, 2022, Nature Communications.

Molecular Dynamics Simulations Reveal the Conformational Transition of GH33 Sialidases

Xueting Cao, Xukai Jiang, Min Xiao, 2023, International journal of molecular sciences.

Structural and dynamic evolution of the amphipathic N-terminus diversifies enzyme thermostability in the glycoside hydrolase family 12.

Xukai Jiang, Lushan Wang, Guanjun Chen, 2016, Physical chemistry chemical physics : PCCP.

Dynamic Perturbation of the Active Site Determines Reversible Thermal Inactivation in Glycoside Hydrolase Family 12

Wen Li, Xukai Jiang, Lushan Wang, 2017, J. Chem. Inf. Model..

Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity.

J. Li, T. Velkov, P. Thompson, 2023, Journal of medicinal chemistry.

An Intelligent Strategy with All-Atom Molecular Dynamics Simulations for the Design of Lipopeptides against Multidrug-Resistant Pseudomonas aeruginosa.

F. Schreiber, J. Li, K. Tran, 2022, Journal of medicinal chemistry.

Docking-guided rational engineering of a macrolide glycosyltransferase glycodiversifies epothilone B

Zheng Zhang, Peng Zhang, Changsheng Wu, 2022, Communications Biology.

Comparative molecular dynamics simulations identify a salt-sensitive loop responsible for the halotolerant activity of GH5 cellulases

Lushan Wang, Yue Zhao, Xukai Jiang, 2021, Journal of biomolecular structure & dynamics.

A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii

F. Schreiber, Lushan Wang, T. Velkov, 2021, Chemical science.

Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin

Casey C. Fowler, Xiang Gao, Hongan Long, 2022, mBio.

Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase

Ruibo Wu, L. Meng, Yuanyuan Jiang, 2023, Nature Communications.

Lipid A Modification and Metabolic Adaptation in Polymyxin-Resistant, New Delhi Metallo-β-Lactamase–Producing Klebsiella pneumoniae

T. Velkov, Yi-yun Liu, Yan Zhu, 2023, Microbiology spectrum.

Structural and dynamic evolution of the amphipathic N-terminus diversifies enzyme thermostability in the glycoside hydrolase family 12.

Xukai Jiang, Guanjun Chen, Lushan Wang, 2016, Physical chemistry chemical physics : PCCP.

Engineering the Relatively Conserved Residues in Active Site Architecture of Thermophilic Chitinase SsChi18A Enhanced Catalytic Activity.

Xukai Jiang, Xiuyun Wu, Xiaomeng Sun, 2023, Biomacromolecules.

Enhanced Sampling Molecular Dynamics Simulations Reveal Transport Mechanism of Glycoconjugate Drugs through GLUT1

Xukai Jiang, Min Xiao, Lushan Wang, 2024, International journal of molecular sciences.

Molecular Insights to the Structure-Interaction Relationships of Human Proton-Coupled Oligopeptide Transporters (PepTs)

Fanfan Zhou, Q. Zhou, Xukai Jiang, 2023, Pharmaceutics.