B. Zordoky

发表

Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline‐induced cardiac hypertrophy

A. El-Kadi, B. Hammock, H. N. Althurwi, 2013, British journal of pharmacology.

Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart

Anwar Anwar-mohamed, A. El-Kadi, H. N. Althurwi, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats.

Anwar Anwar-mohamed, A. El-Kadi, M. Aboutabl, 2010, Toxicology and applied pharmacology.

Modulation of Cytochrome P450 Gene Expression and Arachidonic Acid Metabolism during Isoproterenol-Induced Cardiac Hypertrophy in Rats

A. El-Kadi, M. Aboutabl, Beshay N. Zordoky, 2008, Drug Metabolism and Disposition.

Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases.

A. El-Kadi, Beshay N. Zordoky, B. Zordoky, 2010, Pharmacology & therapeutics.

Metabolomic Fingerprint of Heart Failure with Preserved Ejection Fraction

David S. Wishart, Beomsoo Han, Rupasri Mandal, 2015, PloS one.

Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction

D. Seelig, Beshay N. Zordoky, B. Zordoky, 2020, PloS one.

Isoproterenol-induced Cardiac Dysfunction in Male and Female C57Bl/6 Mice

D. Seelig, B. Zordoky, M. Grant, 2020, bioRxiv.

Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice

D. Seelig, L. Sharkey, B. Zordoky, 2017, Biology of Sex Differences.

Identification of new candidate biomarkers to support doxorubicin treatments in canine cancer patients

P. Villalta, S. Balbo, A. Bartolomucci, 2021, BMC Veterinary Research.

CYP1B1 as a therapeutic target in cardio-oncology

Beshay N. Zordoky, B. Zordoky, M. Grant, 2020, Clinical science.

Cardiomyocyte specific adipose triglyceride lipase overexpression prevents doxorubicin induced cardiac dysfunction in female mice

Petra C. Kienesberger, J. Dyck, P. Kienesberger, 2013, Heart.

The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

F. Apple, I. Matīse, S. Mccune, 2016, Cardio-Oncology.

3‐Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats

A. El-Kadi, M. Aboutabl, Beshay N. Zordoky, 2009, British journal of pharmacology.

Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice.

V. Dolinsky, J. Dyck, L. Jones, 2013, American journal of physiology. Endocrinology and metabolism.

Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice

D. Seelig, Beshay N. Zordoky, L. Sharkey, 2019, PloS one.

Sexual Dimorphism of Doxorubicin-Induced Cardiotoxicity

Beshay N. Zordoky, L. Sharkey, B. Zordoky, 2015 .

Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation.

Anwar Anwar-mohamed, A. El-Kadi, M. Aboutabl, 2010, Pharmacological research.

Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice.

A. El-Kadi, D. Zeldin, M. Edin, 2013, Prostaglandins & other lipid mediators.

Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice

Anwar Anwar-mohamed, A. El-Kadi, B. Zordoky, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

Chronic Doxorubicin Cardiotoxicity Modulates Cardiac Cytochrome P450-Mediated Arachidonic Acid Metabolism in Rats

A. El-Kadi, Beshay N. Zordoky, B. Zordoky, 2012, Drug Metabolism and Disposition.

Cardiovascular ramifications of therapy-induced endothelial cell senescence in cancer survivors.

Beshay N. Zordoky, B. Zordoky, Kevin Agostinucci, 2022, Biochimica et biophysica acta. Molecular basis of disease.

Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure.

A. El-Kadi, Beshay N. Zordoky, B. Zordoky, 2008, Current drug metabolism.

EA.hy926 Cells and HUVECs Share Similar Senescence Phenotypes but Respond Differently to the Senolytic Drug ABT-263

Beshay N. Zordoky, B. Zordoky, M. Grant, 2022, Cells.

Determination of the Dominant Arachidonic Acid Cytochrome P450 Monooxygenases in Rat Heart, Lung, Kidney, and Liver: Protein Expression and Metabolite Kinetics

Anwar Anwar-mohamed, A. El-Kadi, M. Aboutabl, 2012, The AAPS Journal.

AMPK-Dependent Inhibitory Phosphorylation of ACC Is Not Essential for Maintaining Myocardial Fatty Acid Oxidation

J. Dyck, B. Kemp, P. Kienesberger, 2014, Circulation research.

Juvenile exposure to doxorubicin alters the cardiovascular response to adult-onset psychosocial stress in mice

D. Seelig, A. Bartolomucci, Beshay N. Zordoky, 2022, Stress.

Induction of several cytochrome P450 genes by doxorubicin in H9c2 cells.

A. El-Kadi, B. Zordoky, 2008, Vascular pharmacology.

Response to Schoormans.

A. Blaes, S. Konety, B. Zordoky, 2020, Journal of the National Cancer Institute.

H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart.

A. El-Kadi, B. Zordoky, 2007, Journal of pharmacological and toxicological methods.

Inhibition of Soluble Epoxide Hydrolase Confers Cardioprotection and Prevents Cardiac Cytochrome P450 Induction by Benzo(a)pyrene

A. El-Kadi, B. Hammock, M. Aboutabl, 2011, Journal of cardiovascular pharmacology.

Acute Doxorubicin Toxicity Differentially Alters Cytochrome P450 Expression and Arachidonic Acid Metabolism in Rat Kidney and Liver

A. El-Kadi, M. Aboutabl, Beshay N. Zordoky, 2011, Drug Metabolism and Disposition.

Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice.

V. Dolinsky, J. Dyck, S. Davidge, 2013, Biochimica et biophysica acta.

Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence.

L. Niedernhofer, K. Sadak, Beshay N. Zordoky, 2020, Pharmacology & therapeutics.

Cardiovascular Vulnerability to COVID-19 in Cancer Survivors

B. Zordoky, 2020 .

Leveraging the Cardio-Protective and Anticancer Properties of Resveratrol in Cardio-Oncology

Beshay N. Zordoky, B. Zordoky, M. Grant, 2019, Nutrients.

Resveratrol reduces cardiac NLRP3‐inflammasome activation and systemic inflammation to lessen doxorubicin‐induced cardiotoxicity in juvenile mice

D. Eisenstat, J. Dyck, M. Ferdaoussi, 2021, FEBS letters.

Role of NF-κB in the regulation of cytochrome P450 enzymes

A. El-Kadi, Beshay N. Zordoky, Beshay N.M. Zordoky, 2009 .

Role of NF-kappaB in the regulation of cytochrome P450 enzymes.

A. El-Kadi, Ayman O S El-Kadi, Beshay N. Zordoky, 2009, Current drug metabolism.

Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases.

I. M. Robertson, J. Dyck, Beshay N. Zordoky, 2015, Biochimica et biophysica acta.

Clinical and preclinical evidence of sex-related differences in anthracycline-induced cardiotoxicity

C. Shenoy, Beshay N. Zordoky, B. Zordoky, 2018, Biology of Sex Differences.

Role of cytochrome P450–mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy

A. El-Kadi, Beshay N. Zordoky, Mandy M Y Tse, 2013, Drug metabolism reviews.

AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.

P. Light, J. Dyck, B. Kemp, 2015, Cardiovascular research.

2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism.

A. El-Kadi, Beshay N. Zordoky, B. Zordoky, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

Psychological measures of stress and biomarkers of inflammation, aging, and endothelial dysfunction in breast cancer survivors on aromatase inhibitors

A. Blaes, P. Jewett, Beshay N. Zordoky, 2023, Scientific Reports.

The anti-proliferative effect of metformin in triple-negative MDA-MB-231 breast cancer cells is highly dependent on glucose concentration: implications for cancer therapy and prevention.

J. Dyck, M. Sung, Beshay N. Zordoky, 2014, Biochimica et biophysica acta.

Exposure to Doxorubicin Modulates the Cardiac Response to Isoproterenol in Male and Female Mice

Beshay N. Zordoky, B. Zordoky, M. Grant, 2023, Pharmaceuticals.

PHARMACOLOGY AND TOXICOLOGY Opinion

Beshay N. Zordoky, L. Sharkey, B. Zordoky, 2015 .

Metformin mitigates SASP secretion and LPS-triggered hyper-inflammation in Doxorubicin-induced senescent endothelial cells

Beshay N. Zordoky, B. Zordoky, M. Grant, 2023, Frontiers in Aging.

Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes

I. M. Robertson, J. Dyck, A. Bartolomucci, 2018, Cardiovascular research.

Divergent Cardiac Effects of Angiotensin II and Isoproterenol Following Juvenile Exposure to Doxorubicin

J. Dyck, D. Seelig, A. Bartolomucci, 2022, Frontiers in Cardiovascular Medicine.

Doxorubicin Paradoxically Ameliorates Tumor-Induced Inflammation in Young Mice

Flavia E. Popescu, D. Largaespada, Beshay N. Zordoky, 2021, International journal of molecular sciences.

Clinical and preclinical evidence of sex-related differences in anthracycline-induced cardiotoxicity

C. Shenoy, B. Zordoky, Becky Meiners, 2018, Biology of Sex Differences.

Sexual Dimorphism in Doxorubicin-induced Systemic Inflammation: Implications for Hepatic Cytochrome P450 Regulation

B. Zordoky, M. Grant, Ibrahim Y Abdelgawad, 2020, International journal of molecular sciences.

Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice

D. Seelig, Beshay N. Zordoky, L. Sharkey, 2017, Biology of Sex Differences.

Anticancer effects of resveratrol in canine hemangiosarcoma cell lines

D. Seelig, Beshay N. Zordoky, L. Sharkey, 2018, Veterinary and comparative oncology.

Psychosocial stress unmasks latent doxorubicin-induced cardiotoxicity

A. Bartolomucci, B. Zordoky, M. Grant, 2018, Journal of Molecular and Cellular Cardiology.

Determination of the Dominant Arachidonic Acid Cytochrome P450 Monooxygenases in Rat Heart, Lung, Kidney, and Liver: Protein Expression and Metabolite Kinetics

A. El-Kadi, M. Aboutabl, B. Zordoky, 2012, The AAPS Journal.

Canagliflozin mitigates carfilzomib-induced endothelial apoptosis via an AMPK-dependent pathway.

Beshay N. Zordoky, B. Zordoky, M. Grant, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.