E. Maxwell

发表

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

Identification of Neuropsychiatric Copy Number Variants in a Health Care System Population

D. Ledbetter, C. Martin, L. Habegger, 2020, JAMA psychiatry.

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis

Alexander E. Lopez, Grant D. Huang, Yan V. Sun, 2020, Nature Genetics.

Profiling and leveraging relatedness in a precision medicine cohort of 92,455 exomes

Alexander E. Lopez, Tanya M. Teslovich, D. Ledbetter, 2017, bioRxiv.

Profiling and leveraging relatedness in a precision medicine cohort of 92,455 exomes

Alexander E. Lopez, Tanya M. Teslovich, D. Ledbetter, 2017, bioRxiv.

Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease

J. Marchini, S. McCarthy, M. Cantor, 2020, medRxiv.

Genotyping, sequencing and analysis of 140,000 adults from the Mexico City Prospective Study

Alexander E. Lopez, Katherine R. Smith, R. Collins, 2022, bioRxiv.

ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

Alexander E. Lopez, Tanya M. Teslovich, Gaurang C. Patel, 2022, Communications Biology.

Exome sequencing and analysis of 454,787 UK Biobank participants

J. Marchini, G. Abecasis, H. Kang, 2021, Nature.

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Alexander E. Lopez, Alexander Hanbo Li, Andrew L Blumenfeld, 2020, Nature.

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

Medical manifestations and healthcare utilization among adult MyCode participants with neurodevelopmental psychiatric copy number variants

D. Ledbetter, L. Habegger, H. Kirchner, 2021, Genetics in Medicine.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms

Alexander E. Lopez, Dustin N. Hartzel, Andrew L Blumenfeld, 2021, Nature Communications.

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

Alexander E. Lopez, David P. vanMaanen, K. Lunetta, 2022, Nature Genetics.

Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank

Gonçalo Abecasis, Alan R. Shuldiner, Jeffrey Staples, 2019, bioRxiv.

Profiling copy number variation and disease associations from 50,726 DiscovEHR Study exomes

Marylyn D. Ritchie, Alan R. Shuldiner, Jeffrey Staples, 2017, bioRxiv.

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Alexander E. Lopez, Andrew L Blumenfeld, M. McCarthy, 2021, Nature Genetics.

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Alexander E. Lopez, Yan V. Sun, Andrew L Blumenfeld, 2020, Nature Genetics.

Computationally efficient whole-genome regression for quantitative and binary traits

Gonçalo Abecasis, Leland Barnard, Jonathan Marchini, 2020, Nature Genetics.

Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease

Alexander E. Lopez, Eurie L. Hong, G. D. Gatta, 2022, Nature Genetics.

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Tom R. Gaunt, Alexander E. Lopez, Laurent F. Thomas, 2021, Cell.

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Alexander E. Lopez, Andrew L Blumenfeld, J. Marchini, 2020, Nature.

Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes

Alexander E. Lopez, Dustin N. Hartzel, Andrew L Blumenfeld, 2021, Scientific Reports.

Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals

J. Marchini, G. Abecasis, H. Kang, 2021, The American Journal of Human Genetics.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, J. Szustakowski, 2020, medRxiv : the preprint server for health sciences.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, G. Abecasis, 2020, medRxiv.

Advancing Human Genetics Research and Drug Discovery through Exome Sequencing of the UK Biobank

Alexander E. Lopez, Jason A. Grundstad, Sri V. V. Deevi, 2020, medRxiv.

High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease

Alexander E. Lopez, Manuel A. Rivas, Manuel A Rivas, 2022, Nature Genetics.

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

Andrew L Blumenfeld, G. Abecasis, H. Kang, 2020, Nature Communications.

Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease

Alexander Hanbo Li, J. Marchini, S. Balasubramanian, 2020, medRxiv.

CLAMMS: a scalable algorithm for calling common and rare copy number variants from exome sequencing data

Frederick E. Dewey, Alexander E. Lopez, John D. Overton, 2015, Bioinform..

Open-source mapping and variant calling for large-scale NGS data from original base-quality scores

William J. Salerno, Olga Krasheninina, Yih-Chii Hwang, 2020, bioRxiv.

A deep catalog of protein-coding variation in 985,830 individuals

Alexander E. Lopez, R. Collins, G. Abecasis, 2023, bioRxiv.

Thrombotic Risk Determined by STAB 2 Variants in a Population-Based Cohort Study.

Alexander E. Lopez, Andrew L Blumenfeld, G. Abecasis, 2021, Circulation. Genomic and precision medicine.

Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals

Alexander E. Lopez, Andrew L Blumenfeld, G. Abecasis, 2020, Biological Psychiatry.

Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

Yield of genetic association signals from genomes, exomes, and imputation in the UK biobank

G. Abecasis, S. Balasubramanian, W. Salerno, 2023, medRxiv.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, J. Szustakowski, 2020, medRxiv : the preprint server for health sciences.

Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

Sri V. V. Deevi, J. Szustakowski, S. Balasubramanian, 2021, Nature Genetics.

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Tom R. Gaunt, Alexander E. Lopez, Laurent F. Thomas, 2021, Cell.

A deep catalog of protein-coding variation in 985,830 individuals

Alexander E. Lopez, R. Collins, G. Abecasis, 2023, bioRxiv.

Genotyping, sequencing and analysis of 140,000 adults from Mexico City

R. Collins, S. Balasubramanian, A. Hawes, 2023, Nature.