N. Hariharan

发表

Fat Oxidation, Fitness and Skeletal Muscle Expression of Oxidative/Lipid Metabolism Genes in South Asians: Implications for Insulin Resistance?

N. Forouhi, J. Gill, N. Sattar, 2010, PloS one.

Expression of Human Hepatic Glucokinase in Transgenic Mice Liver Results in Decreased Glucose Levels and Reduced Body Weight

A. Treloar, C. Arbeeny, K. Mookhtiar, 1997, Diabetes.

Design, synthesis, and structure-activity relationships of piperidine and dehydropiperidine carboxylic acids as novel, potent dual PPARalpha/gamma agonists.

Litao Zhang, K. O'Malley, P. Cheng, 2008, Bioorganic & medicinal chemistry letters.

Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists.

Wei Wang, Jonathan Lippy, Arthur M Doweyko, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of novel pyrrolidine acid analogs as potent dual PPARα/γ agonists.

Weiqi Wang, A. Doweyko, T. Harrity, 2015, Bioorganic & medicinal chemistry letters.

Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor alpha/gamma dual agonist with efficacious glucose and lipid-lowering activities.

Weiqi Wang, A. Doweyko, W. Humphreys, 2005, Journal of medicinal chemistry.

Discovery of tertiary aminoacids as dual PPARα/γ agonists-I

Wei Wang, Wei Sun, Zhengping Ma, 2007 .

The Dual Peroxisome Proliferator-Activated Receptor (cid:1) / (cid:2) Activator Muraglitazar Prevents the Natural Progression of Diabetes in db/db Mice

Simeon I. Taylor, E. Janovitz, E. Tozzo, 2007 .

Design and synthesis of novel spirocyclic carboxylic acids as potent and orally bioavailable DGAT1 inhibitors and their biological evaluation.

Sudhir Ravula, K. Mookhtiar, Atul Tiwari, 2022, Bioorganic & medicinal chemistry letters.

Muraglitazar, a novel dual (alpha/gamma) peroxisome proliferator-activated receptor activator, improves diabetes and other metabolic abnormalities and preserves beta-cell function in db/db mice.

R. Gregg, W. Fenderson, Wen-pin Yang, 2006, Diabetes.

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.

Richard D. Gregg, R. Gregg, S. Lira, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of Potent and Selective A2A Antagonists with Efficacy in Animal Models of Parkinson's Disease and Depression.

A. Chugh, S. Chaudhary, D. Barawkar, 2017, ACS medicinal chemistry letters.

Discovery of azetidinone acids as conformationally-constrained dual PPARalpha/gamma agonists.

A. Doweyko, T. Harrity, Litao Zhang, 2008, Bioorganic & medicinal chemistry letters.

Discovery and evaluation of 1H-pyrrolo[2,3-b]pyridine based selective and reversible small molecule BTK inhibitors for the treatment of rheumatoid arthritis.

A. Nadeem, J. Mavinahalli, B. Kulkarni, 2017, Bioorganic & medicinal chemistry letters.

Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor &ggr; agonists

T. Delmonte, Lester Hui, W. J. Geese, 2008, Pharmacogenetics and genomics.

A rapid, homogeneous, fluorescence polarization binding assay for peroxisome proliferator-activated receptors alpha and gamma using a fluorescein-tagged dual PPARα/γ activator

R. Seethala, Rajasree Golla, Zhengping Ma, 2007 .

Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in db/db Mice

Michael Cap, R. Gregg, W. Fenderson, 2006 .

Comparative Metabolism of Radiolabeled Muraglitazar in Animals and Humans by Quantitative and Qualitative Metabolite Profiling

W. Humphreys, Haiying Zhang, Litao Zhang, 2007, Drug Metabolism and Disposition.

The Dual Peroxisome Proliferator-Activated Receptor α/γ Activator Muraglitazar Prevents the Natural Progression of Diabetes in db/db Mice

Simeon I. Taylor, E. Janovitz, E. Tozzo, 2007, Journal of Pharmacology and Experimental Therapeutics.

The dual peroxisome proliferator-activated receptor alpha/gamma activator muraglitazar prevents the natural progression of diabetes in db/db mice.

Simeon I. Taylor, E. Janovitz, E. Tozzo, 2007, The Journal of pharmacology and experimental therapeutics.

Pharmacokinetics of muraglitazar (BMS-298585), a dual peroxisome proliferator-activated receptors (PPAR) alpha and gamma activator, in mice, rats, dogs, and monkeys.

W. Humphreys, B. Koplowitz, V. Hosagrahara, 2006, Xenobiotica; the fate of foreign compounds in biological systems.