S. Wein

发表

β-Hydroxy- and β-Aminophosphonate Acyclonucleosides as Potent Inhibitors of Plasmodium falciparum Growth.

S. Peyrottes, C. Périgaud, Thomas Cheviet, 2020, Journal of medicinal chemistry.

Exploration of potential prodrug approach of the bis-thiazolium salts T3 and T4 for orally delivered antimalarials.

H. Vial, S. Peyrottes, M. Boisbrun, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and antimalarial activity of new 1,12-bis(N,N'-acetamidinyl)dodecane derivatives.

H. Vial, S. Wein, M. Ouattara, 2007, Bioorganic & medicinal chemistry letters.

Antiplasmodial Properties of Acyl-Lysyl Oligomers in Culture and Animal Models of Malaria

H. Vial, H. Ginsburg, M. Krugliak, 2011, Antimicrobial Agents and Chemotherapy.

Quantitation of SAR97276 in mouse tissues by rapid resolution liquid chromatography-mass spectrometry.

H. Vial, F. Bressolle, Florence Gattacceca, 2009, Journal of separation science.

Quantitative analysis of a bis-thiazolium antimalarial compound, SAR97276, in mouse plasma and red blood cell samples, using liquid chromatography mass spectrometry.

H. Vial, F. Bressolle, D. Margout, 2008, Journal of pharmaceutical and biomedical analysis.

Pharmacological Properties of a New Antimalarial Bisthiazolium Salt, T3, and a Corresponding Prodrug, TE3

H. Vial, F. Bressolle, O. Nicolas, 2005, Antimicrobial Agents and Chemotherapy.

Mediation of annexin 1 secretion by a probenecid-sensitive ABC-transporter in rat inflamed mucosa.

F. Pons, S. Wein, J. Laffitte, 2004, Biochemical pharmacology.

Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites

J. Mergny, Jose-Juan Lopez-Rubio, E. Gazanion, 2020, PLoS genetics.

Mono- and bis-thiazolium salts have potent antimalarial activity.

H. Vial, E. Rubi, P. Arnal, 2005, Journal of medicinal chemistry.

Synthesis and Evaluation of Hybrid Bis‐cationic Salts as Antimalarial Drugs

H. Vial, T. Durand, S. Denoyelle, 2010, ChemMedChem.

Choline Analogues in Malaria Chemotherapy

H. Vial, S. Peyrottes, C. Périgaud, 2012, Current pharmaceutical design.

Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.

S. Peyrottes, I. Lefebvre-Tournier, Thomas Cheviet, 2019, Journal of medicinal chemistry.

Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials.

H. Vial, F. Bressolle, T. Durand, 2019, Bioorganic & medicinal chemistry letters.

Disulfide prodrugs of albitiazolium (T3/SAR97276): synthesis and biological activities.

H. Vial, M. Hamel, S. Peyrottes, 2012, Journal of medicinal chemistry.

Uncovering new structural insights for antimalarial activity from cost-effective aculeatin-like derivatives.

A. Miele, H. Vial, Y. Wong, 2015, Organic & biomolecular chemistry.

Synthesis of an Uncharged Tetra-cyclopeptide Acting as a Transmembrane Carrier: Enhanced Cellular and Nuclear Uptake.

H. Vial, Y. Wong, M. Cuendet, 2017, Organic letters.

Development of the First Oral Bioprecursors of Bis‐alkylguanidine Antimalarial Drugs

H. Vial, T. Durand, M. Maynadier, 2014, ChemMedChem.

Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways[S]

Eric Maréchal, H. Vial, E. Maréchal, 2010, Journal of Lipid Research.

Statistical Model To Evaluate In Vivo Activities of Antimalarial Drugs in a Plasmodium cynomolgi-Macaque Model for Plasmodium vivax Malaria

H. Vial, A. Thomas, E. Remarque, 2008, Antimicrobial Agents and Chemotherapy.

Plasmodium cynomolgi-macaque model for Plasmodium vivax malaria

H. Vial, A. Thomas, E. Remarque, 2008 .

Prevalence of mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, and association with ex vivo susceptibility to common anti-malarial drugs against African Plasmodium falciparum isolates

S. Ranque, P. Bastien, M. Drancourt, 2020, Malaria Journal.

Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny

J. Dubremetz, Y. Bordat, W. Daher, 2018, Cellular and Molecular Life Sciences.

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite[S]

H. Vial, K. Wengelnik, M. Maynadier, 2018, Journal of Lipid Research.

Potent Antihematozoan Activity of Novel Bisthiazolium Drug T16: Evidence for Inhibition of Phosphatidylcholine Metabolism in Erythrocytes Infected with Babesia and Plasmodium spp

H. Vial, J. Dubremetz, G. Biagini, 2006, Antimicrobial Agents and Chemotherapy.

Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.

H. Vial, P. Denti, J. Breytenbach, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6

H. Vial, Y. Wong, M. Cuendet, 2017, ACS omega.

Evaluation of Bis‐Alkylamidoxime O‐Alkylsulfonates as Orally Available Antimalarials

H. Vial, T. Durand, S. Wein, 2012, ChemMedChem.

Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate

H. Vial, Y. Bordat, S. Maheshwari, 2012, British journal of pharmacology.

New Insight into the Mechanism of Accumulation and Intraerythrocytic Compartmentation of Albitiazolium, a New Type of Antimalarial

H. Vial, Y. Bordat, L. Fraisse, 2014, Antimicrobial Agents and Chemotherapy.

Type of Antimalarial Compartmentation of Albitiazolium , a New Accumulation and Intraerythrocytic New Insight into the Mechanism of

H. Vial, Y. Bordat, S. Peyrottes, 2014 .

New bis-thiazolium analogues as potential antimalarial agents: design, synthesis, and biological evaluation.

H. Vial, S. Peyrottes, C. Périgaud, 2013, Journal of medicinal chemistry.

Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids

H. Vial, L. Wiesner, J. Norman, 2013, Malaria Journal.

Lipids as drug targets for malaria therapy.

H. Vial, L. Fraisse, S. Peyrottes, 2011 .

Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors.

H. Vial, F. Bressolle, Florence Gattacceca, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis and Evaluation of Bis‐Thiazolium Salts as Potential Antimalarial Drugs

H. Vial, S. Peyrottes, C. Périgaud, 2010, ChemMedChem.

Reliability of Antimalarial Sensitivity Tests Depends on Drug Mechanisms of Action

H. Vial, L. Fraisse, S. Peyrottes, 2010, Journal of Clinical Microbiology.

Prodrugs of bisthiazolium salts are orally potent antimalarials.

H. Vial, F. Bressolle, O. Nicolas, 2004, Proceedings of the National Academy of Sciences of the United States of America.

N-substituted bis-C-alkyloxadiazolones as dual effectors: efficient intermediates to amidoximes or amidines and prodrug candidates of potent antimalarials.

T. Durand, S. Wein, M. Degardin, 2009, Bioorganic & medicinal chemistry letters.

Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny

J. Dubremetz, Y. Bordat, W. Daher, 2018, Cellular and Molecular Life Sciences.