C. J. Pyle

Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis

A. Gaggar, J. Blalock, A. Bush, 2020, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection

M. Birrell, J. Harker, S. Akthar, 2017, Thorax.

Targeting the ICOS/ICOS‐L pathway in a mouse model of established allergic asthma disrupts T follicular helper cell responses and ameliorates disease

J. Harker, C. Lloyd, C. J. Pyle, 2018, Allergy.

Therapeutic ICOS blockade reduces T follicular helper cells and improves allergic airway disease

J. Harker, C. J. Pyle, S. Walker, 2018, bioRxiv.

Enhanced IL-2 in early life limits the development of TFH and protective antiviral immunity

J. Tregoning, J. Harker, C. Lloyd, 2021, The Journal of experimental medicine.

Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology

J. Harker, C. J. Pyle, F. Uwadiae, 2017, PLoS pathogens.

Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte–dendritic cell antigen presentation

L. Carlin, J. Vuononvirta, S. Akthar, 2019, Science Immunology.

Matrix Metalloproteinase-12 Supports Pulmonary B Cell Follicle Formation and Local Antibody Responses During Asthma

J. Harker, T. Hussell, C. Lloyd, 2022, American journal of respiratory and critical care medicine.