H. Haas

发表

IL-4–Secreting Secondary T Follicular Helper (Tfh) Cells Arise from Memory T Cells, Not Persisting Tfh Cells, through a B Cell–Dependent Mechanism

B. Everts, A. Smith, E. Pearce, 2015, The Journal of Immunology.

In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E‐bound allergen

A. Petersen, W. Becker, M. Stöcker, 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Mapping of IgE-binding epitopes on the recombinant major group I allergen of velvet grass pollen, rHol l 1.

M. Schlaak, A. Petersen, W. Becker, 1997, The Journal of allergy and clinical immunology.

The Potential Allergenicity of Two 2S Albumins from Soybean (Glycine max): A Protein Microarray Approach

P. Shewry, B. Niggemann, Jing Lin, 2006, International Archives of Allergy and Immunology.

Early Interleukin–4: Its Role in the Switch towards a Th2 Response and IgE–Mediated Allergy

M. Schlaak, M. Holland, Franco H Falcone, 1999, International Archives of Allergy and Immunology.

Human basophils release interleukin‐4 after stimulation with Schistosoma mansoni egg antigen

M. Schlaak, Franco H Falcone, B. Gibbs, 1996, European journal of immunology.

A Crystallin Fold in the Interleukin-4-inducing Principle of Schistosoma mansoni Eggs (IPSE/α-1) Mediates IgE Binding for Antigen-independent Basophil Activation*

T. Madl, M. Sattler, K. Tripsianes, 2015, The Journal of Biological Chemistry.

The Live Basophil Allergen Array (LBAA): A Pilot Study

Jing Lin, M. Alcocer, B. Gibbs, 2009 .

A novel tool for the detection of allergic sensitization combining protein microarrays with human basophils

S. Vieths, Franco H Falcone, M. Alcocer, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Interleukin-4-Inducing Principle from Schistosoma mansoni Eggs Contains a Functional C-Terminal Nuclear Localization Signal Necessary for Nuclear Translocation in Mammalian Cells but Not for Its Uptake

B. Everts, A. Jones, S. Stolnik, 2011, Infection and Immunity.

Structural characterization of glycans on omega-1, a major Schistosoma mansoni egg glycoprotein that drives Th2 responses.

A. Deelder, M. Wuhrer, M. Doenhoff, 2010, Journal of proteome research.

Cutting Edge: IPSE/alpha-1, a Glycoprotein from Schistosoma mansoni Eggs, Induces IgE-Dependent, Antigen-Independent IL-4 Production by Murine Basophils In Vivo1

E. Pearce, M. Doenhoff, M. Mohrs, 2007, The Journal of Immunology.

Molecular characterization of omega-1: a hepatotoxic ribonuclease from Schistosoma mansoni eggs.

C. Grevelding, M. Wuhrer, K. Hoffmann, 2005, Molecular and biochemical parasitology.

Targeted Glycoproteomic Analysis Reveals That Kappa-5 is a Major, Uniquely Glycosylated Component of Schistosoma mansoni Egg Antigens*

A. Deelder, M. Wuhrer, M. Doenhoff, 2011, Molecular & Cellular Proteomics.

Characterisation and partial purification of Schistosoma mansoni egg-derived pro-angiogenic factor.

K. Preissner, O. Liang, S. Kanse, 2005, Molecular and biochemical parasitology.

A monoclonal antibody detecting dipeptidylpeptidase IV in human tissue

A. Feller, H. Radzun, M. Parwaresch, 2004, Virchows Archiv A.

Differential mediator release from basophils of allergic and non‐allergic asthmatic patients after stimulation with anti‐IgE and C5a

M. Schlaak, J. Schreiber, H. Haas, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Initial FcɛRI-mediated signal strength plays a key role in regulating basophil signaling and deactivation

D. Zillikens, M. Huber, B. Gibbs, 2006 .

Original articles Initial FceRI-mediated signal strength plays a key role in regulating basophil signaling and deactivation

D. Zillikens, M. Huber, B. Gibbs, 2006 .

Interleukin-4 production from human basophils is critically dependent on the storage conditions employed prior to stimulation

B. Gibbs, H. Haas, A. Gronow, 2003, Inflammation Research.

Rapamycin and omega‐1: mTOR‐dependent and ‐independent Th2 skewing by human dendritic cells

M. Yazdanbakhsh, H. Smits, B. Guigas, 2013, Immunology and cell biology.

Characterization of a human-human hybridoma antibody, C-OU1, directed against a colon tumor-associated antigen.

H. Ditzel, J. Jensenius, J. Chemnitz, 1992, Hybridoma.

Staining pattern of seven monoclonal anti-CD26 antibodies in leprosy: implications for the use of CD26 as a surrogate marker of a human Th1-like reaction

J. Gerdes, H. Flad, D. Scheel-Toellner, 1998, Virchows Archiv.

A human in vitro granuloma model for the investigation of multinucleated giant cell and granuloma formation.

J. Gerdes, U. Seitzer, H. Haas, 2001, Histology and histopathology.

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

B. Everts, E. Pearce, M. Yazdanbakhsh, 2012, The Journal of experimental medicine.

Different cytokine patterns correlate with the extension of disease in pulmonary tuberculosis.

P. Zipfel, M. Schlaak, G. Zissel, 1999, European cytokine network.

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).

C. Mueller-Dieckmann, G. Hatzopoulos, G. Schramm, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purified human peripheral blood basophils release interleukin‐13 and preformed interleukin‐4 following immunological activation

Franco H Falcone, B. Gibbs, H. Wolff, 1996, European journal of immunology.

A three-step procedure for the purification of human basophils from buffy coat blood

E. Vollmer, Franco H Falcone, B. Gibbs, 1997, Inflammation Research.

The S. mansoni glycoprotein ω‐1 induces Foxp3 expression in NOD mouse CD4+ T cells

S. Gibbs, A. Cooke, P. Zaccone, 2011, European journal of immunology.

Microbial Biology Surface expression patterns of de fi ned glycan antigens change during Schistosoma mansoni cercarial transformation and development of schistosomula

C. Hokke, A. V. Diepen, A. Homann, 2015 .

Purification of morphologically and functionally intact human basophils to near homogeneity.

M. Ernst, M. Schlaak, H. Körber, 1999, Journal of immunological methods.

Initial Fc epsilon RI-mediated signal strength plays a key role in regulating basophil signaling and deactivation.

D. Zillikens, M. Huber, B. Gibbs, 2006, The Journal of allergy and clinical immunology.

Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13

M. Doenhoff, G. Schramm, H. Haas, 2018, Front. Immunol..

Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model

J. Keiser, Nada Abla, H. Haas, 2017, PLoS neglected tropical diseases.

Human basophils are a source of ‐ and are differentially activated by ‐ IL‐31

B. Eiz-Vesper, B. Gibbs, A. Kapp, 2017, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses

B. Everts, M. Yazdanbakhsh, H. Smits, 2009, The Journal of experimental medicine.

Antibody responses induced by Trichobilharzia regenti antigens in murine and human hosts exhibiting cercarial dermatitis

M. Kašný, P. Horák, L. Kolářová, 2008, Parasite immunology.

Basic Mechanisms in Allergic Disease Title : Human Basophils are Differentially Activated by and are a Source of IL-31 Running title : IL-31 activates human basophils

B. Eiz-Vesper, B. Gibbs, A. Kapp, 2016 .

The Schistosoma mansoni T2 ribonuclease omega-1 modulates inflammasome-dependent IL-1β secretion in macrophages.

S. Gibbs, A. Cooke, P. Zaccone, 2015, International journal for parasitology.

Th2 immune response against Schistosoma mansoni infection.

G. Schramm, H. Haas, 2010, Microbes and infection.

Dietary lectins can induce in vitro release of IL‐4 and IL‐13 from human basophils

M. Schlaak, W. Becker, H. Gabius, 1999, European journal of immunology.

In vitro synthesis of human IgE is suppressed by human IgG

M. Schlaak, H. Haas, 1995, Journal of Clinical Immunology.

Modulation of basophil activity: a novel function of the neuropeptide α-melanocyte-stimulating hormone.

R. Paus, T. Luger, E. Ponimaskin, 2012, The Journal of allergy and clinical immunology.

Echinococcus multilocularis metacestode extract triggers human basophils to release interleukin‐4

K. Brehm, B. Gibbs, M. Doenhoff, 2004, Parasite immunology.

Specific glycan elements determine differential binding of individual egg glycoproteins of the human parasite Schistosoma mansoni by host C-type lectin receptors.

R. Versteegh, A. Deelder, M. Yazdanbakhsh, 2012, International journal for parasitology.

The human basophil: a new appreciation of its role in immune responses.

Franco H Falcone, B. Gibbs, H. Haas, 2000, Blood.

Primary Identification, Biochemical Characterization, and Immunologic Properties of the Allergenic Pollen Cyclophilin Cat r 1*

A. Petersen, R. London, G. Mueller, 2014, The Journal of Biological Chemistry.

Schistosoma mansoni infection reduces the incidence of murine cerebral malaria

J. Golenser, E. Flescher, M. Doenhoff, 2010, Malaria Journal.

Surface expression patterns of defined glycan antigens change during Schistosoma mansoni cercarial transformation and development of schistosomula.

A. van Diepen, C. Hokke, Vincent P. van Hensbergen, 2015, Glycobiology.

Molecular Characterization of an Interleukin-4-inducing Factor from Schistosoma mansoni Eggs*

Franco H Falcone, U. Mamat, M. Doenhoff, 2003, The Journal of Biological Chemistry.

A glycoprotein from Schistosoma mansoni eggs binds non‐antigen‐specific immunoglobulin E and releases interleukin‐4 from human basophils

M. Schlaak, Franco H Falcone, G. Schramm, 2001, Parasite immunology.

Immunoblotting techniques for the detection of low level homogeneous immunoglobulin components in serum.

A. J. van der Sluijs-Gelling, M. V. van Tol, J. Radl, 1990, Journal of immunological methods.

IPSE/alpha‐1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core‐difucosylated N‐glycans

A. Deelder, M. Wuhrer, M. Doenhoff, 2006, The FEBS journal.

IPSE/alpha-1: a major immunogenic component secreted from Schistosoma mansoni eggs.

P. Chiodini, C. Grevelding, J. Knobloch, 2006, Molecular and biochemical parasitology.

In vitro cultivation of third-stage larvae of Brugia malayi to the young adult stage.

M. Schlaak, Franco H Falcone, H. Zahner, 1995, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

Drug-Induced Exposure of Schistosoma mansoni Antigens SmCD59a and SmKK7

C. Grevelding, M. Yazdanbakhsh, R. Wilson, 2015, PLoS neglected tropical diseases.

Early IgE-dependent release of IL-4 and IL-13 from leukocytes is restricted to basophils: a comparison with other granulocytes and mononuclear cells

B. Gibbs, H. Wolff, H. Haas, 2000, Inflammation Research.

Do infections induce monoclonal immunoglobulin components?

M. Schlaak, H. Schmitz, J. Radl, 1990, Clinical and experimental immunology.

Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs.

T. Goldmann, S. Beckmann, C. Grevelding, 2009, Molecular and biochemical parasitology.

Calcium-dependent and calcium-independent signals in the conglutinin-binding assay (KgBa) for immune complexes. Influence of anti-collagen-antibodies.

J. Jensenius, U. Holmskov, B. Teisner, 1992, Journal of immunological methods.

Discontinuous IgE‐binding epitopes contain multiple continuous epitope regions: results of an epitope mapping on recombinant Hol l 5, a major allergen from velvet grass pollen

M. Schlaak, A. Petersen, W. Becker, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.