S. B. Singh

发表

Actinoplanic acids A and B as novel inhibitors of farnesyl-protein transferase

G. Garrity, J. Gibbs, O. Genilloud, 1995, Applied Microbiology and Biotechnology.

Kampanols: novel Ras farnesyl-protein transferase inhibitors from Stachybotrys kampalensis.

K. Silverman, D. Zink, R. Lingham, 1998, Bioorganic & medicinal chemistry letters.

Oreganic acid, a potent inhibitor of ras farnesyl-protein transferase.

K. Silverman, G. Bills, C. Cascales, 1997, Biochemical and biophysical research communications.

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.

M. S. Singh, E. Scolnick, N. Kohl, 1993, The Journal of biological chemistry.

Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.

E. Hamel, C. Lin, G. Pettit, 1988, Molecular pharmacology.

Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.

D M Schmatz, M. Bednarek, D. Schmatz, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Structure, histone deacetylase, and antiprotozoal activities of apicidins B and C, congeners of apicidin with proline and valine substitutions.

D. Schmatz, J. Liesch, D. Zink, 2001, Organic letters.

Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.

M. Malamas, D. Kitchen, R. Nilakantan, 2000, Journal of medicinal chemistry.

A novel antiviral agent which inhibits the endonuclease of influenza viruses

J. Tomassini, J. Tkacz, J. Hastings, 1996, Antimicrobial agents and chemotherapy.

Antineoplastic agents, 120. Pancratium littorale.

G. Cragg, D. L. Herald, G. Pettit, 1986, Journal of natural products.

Tetrahydroisoquinoline derivatives containing a benzenesulfonamide moiety as potent, selective human beta3 adrenergic receptor agonists.

M. Fisher, M. Wyvratt, A. Weber, 2000, Bioorganic & medicinal chemistry letters.

Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a)

M. Boyd, R. Pettit, E. Hamel, 1995, Journal of medicinal chemistry.

Structure, histone deacetylase, and antiprotozoal activities of apicidins B and C, congeners of apicidin with proline and valine substitutions.

D. Schmatz, J. Liesch, D. Zink, 2001, Organic letters.

Monoamine Oxidase Inhibitory and Anticonvulsant Activities of Some Substituted Isatin Semicarbazones

Ashok Kumar, S. B. Singh, I. Awheda, 2014 .

Efficient syntheses, human and yeast farnesyl-protein transferase inhibitory activities of chaetomellic acids and analogues.

K. Silverman, J. Williamson, R. Lingham, 2000, Bioorganic & medicinal chemistry.

Kinetic evidence for a charge-transfer mechanism in the interaction of ammonia with 2,4-dinitrophenylhydrazine in dimethylsulphoxide.

S. B. Singh, I. A. Khan, S. Iqbal, 1990, Talanta.

Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.

M. Malamas, D. Kitchen, R. Nilakantan, 2000, Journal of medicinal chemistry.

Phospholipase A(2) with platelet aggregation inhibitor activity from Austrelaps superbus venom: protein purification and cDNA cloning.

R. Kini, A. Armugam, K. Jeyaseelan, 2000, Archives of biochemistry and biophysics.

Effect of bis(acetylacetonato) copper(II) catalyst on the reaction of benzoylphenyldiazomethane with primary amines. A novel example of insertion of benzoylphenylcarbene into N—H bonds of amines

S. B. Singh, K. N. Mehrotra, 1981 .

Spirocyclic Scaffolds in Drug Discovery

Y. Zheng, C. Tice, S. B. Singh, 2017 .

Candelalides A-C: novel diterpenoid pyrones from fermentations of Sesquicillium candelabrum as blockers of the voltage-gated potassium channel Kv1.3.

G. Bills, D. Zink, M. Goetz, 2001, Organic letters.

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

D. Alberts, E. Hamel, Sheo B. Singh, 1989, Experientia.

Syntheses of N-substituted 3,3,4-triphenyl-4-benzoylazetidin-2-ones and 3′,3′-diphenyl spiro(acenaphthen-1-one-2,4′-azetidin-2′-ones); novel examples exhibiting a high reactivity of imino group in ketoimines

S. B. Singh, K. N. Mehrotra, 1982 .

The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid-hydrolysis products of chloropeptin I.

O. Genilloud, K. Silverman, B. Heimbuch, 2001, Journal of natural products.

Isolation, structure, synthesis, and antimitotic properties of combretastatins B-3 and B-4 from Combretum caffrum.

E. Hamel, G R Pettit, S B Singh, 1988, Journal of natural products.

Antineoplastic agents, 122. Constituents of Combretum caffrum.

G. Cragg, G R Pettit, G M Cragg, 1987, Journal of natural products.

Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum.

E. Hamel, G R Pettit, S B Singh, 1987, Journal of natural products.

Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues.

P. Graham, R. Reamer, S. B. Singh, 2001, Bioorganic & medicinal chemistry letters.

Ophiobolin M and analogues, noncompetitive inhibitors of ivermectin binding with nematocidal activity.

J. Schaeffer, J. Tkacz, D. Zink, 1996, Bioorganic & medicinal chemistry.

Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase.

K. Wilson, K. Silverman, D. Zink, 1993, Journal of natural products.

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA.

D. Patel, B. Hingerty, S. Broyde, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Clavaric acid: a triterpenoid inhibitor of farnesyl-protein transferase from Clavariadelphus truncatus.

K. Silverman, F. Peláez, D. Zink, 1998, Journal of natural products.

Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.

N. Kohl, J. Gibbs, S. Graham, 1998, Journal of medicinal chemistry.

Antineoplastic agents, 162. Zephyranthes candida.

G. Cragg, J. Duke, G. Pettit, 1990, Journal of natural products.

Synthesis of natural flutimide and analogous fully substituted pyrazine-2,6-diones, endonuclease inhibitors of influenza virus.

J. Tomassini, S. B. Singh, S. Singh, 2001, The Journal of organic chemistry.

Structures of the (+)- and (-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne adducts to guanine-N2 in a duplex dodecamer.

U. Singh, B. Hingerty, S. Broyde, 1991, Cancer research.

Interactions between DNA polymerase beta and the major covalent adduct of the carcinogen (+)-anti-benzo[a]pyrene diol epoxide with DNA at a primer-template junction.

B. Hingerty, S. Broyde, W. Beard, 1998, Biochemistry.

Chemical and enzymatic modifications of integric acid and HIV-1 integrase inhibitory activity.

D. Hazuda, P. Felock, S. B. Singh, 2000, Bioorganic & medicinal chemistry letters.

Coprophilin: an anticoccidial agent produced by a dung inhabiting fungus.

D. Schmatz, G. Bills, R. Giacobbe, 1998, Bioorganic & medicinal chemistry letters.